103 items (Drosophila virilis) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	DvirGJ21532	Uncharacterized protein. (8884 aa)
	DvirGJ15244	Uncharacterized protein, isoform AA; Belongs to the MAGUK family. (1334 aa)
	DvirGJ18028	Uncharacterized protein, isoform B; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1442 aa)
	DvirGJ19131	Uncharacterized protein, isoform B. (704 aa)
	DvirGJ18738	Uncharacterized protein, isoform U. (1952 aa)
	DvirGJ21177	Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (599 aa)
	DvirGJ23383	Non-specific serine/threonine protein kinase. (695 aa)
	DvirGJ21241	Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (582 aa)
	DvirGJ22953	Uncharacterized protein, isoform C. (542 aa)
	DvirGJ16405	Uncharacterized protein, isoform B. (737 aa)
	DvirGJ12319	Uncharacterized protein, isoform B. (469 aa)
	DvirGJ25775	Uncharacterized protein; Belongs to the protein kinase superfamily. Tyr protein kinase family. (1086 aa)
	DvirGJ13828	Death domain-containing protein. (4880 aa)
	DvirGJ13827	Uncharacterized protein, isoform B. (1089 aa)
	DvirGJ16275	Uncharacterized protein, isoform C. (566 aa)
	DvirGJ26067	Uncharacterized protein. (2317 aa)
	DvirGJ19553	Mothers against decapentaplegic homolog. (510 aa)
	DvirGJ23889	Uncharacterized protein, isoform B. (1372 aa)
	DvirGJ19344	Actin-related protein 2; ATP-binding component of the Arp2/3 complex, a multiprotein complex that mediates actin polymerization upon stimulation by nucleation-promoting factor (NPF). The Arp2/3 complex mediates the formation of branched actin networks in the cytoplasm, providing the force for cell motility. Seems to contact the pointed end of the daughter actin filament. (399 aa)
	DvirGJ26812	Protein kinase domain-containing protein. (223 aa)
	DvirGJ11623	Uncharacterized protein, isoform B. (526 aa)
	DvirGJ12606	Tudor domain-containing protein. (233 aa)
	DvirGJ12809	P66_CC domain-containing protein. (936 aa)
	DvirGJ11345	Uncharacterized protein, isoform A. (470 aa)
	DvirGJ12497	Protein kinase domain-containing protein. (807 aa)
	DvirGJ12912	Protein kinase domain-containing protein. (1129 aa)
	DvirGJ11870	Uncharacterized protein, isoform A. (996 aa)
	DvirGJ12406	Uncharacterized protein. (775 aa)
	DvirGJ13545	PKD_channel domain-containing protein. (661 aa)
	DvirGJ13615	Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (928 aa)
	DvirGJ12210	Protein kinase domain-containing protein. (227 aa)
	DvirGJ11567	Uncharacterized protein, isoform A; Belongs to the G-protein coupled receptor 1 family. (600 aa)
	DvirGJ12169	Uncharacterized protein. (266 aa)
	DvirGJ13209	Uncharacterized protein. (192 aa)
	DvirGJ12130	IlGF domain-containing protein. (135 aa)
	DvirGJ12704	Uncharacterized protein. (2290 aa)
	DvirGJ13271	Uncharacterized protein; Belongs to the actin family. (418 aa)
	DvirGJ13897	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (434 aa)
	stau	Stau. (1063 aa)
	DvirGJ22222	Uncharacterized protein; Belongs to the G-protein coupled receptor 2 family. (3654 aa)
	DvirGJ21698	Septin-type G domain-containing protein; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family. (538 aa)
	DvirGJ20054	Receptor protein-tyrosine kinase. (1438 aa)
	DvirGJ22317	Syndecan; Cell surface proteoglycan; Belongs to the syndecan proteoglycan family. (433 aa)
	gbb	Gbb. (436 aa)
	DvirGJ20440	Uncharacterized protein, isoform C. (364 aa)
	DvirGJ22485	PX domain-containing protein. (401 aa)
	DvirGJ21907	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (1014 aa)
	DvirGJ21970	TCTP domain-containing protein; Belongs to the TCTP family. (172 aa)
	DvirGJ22011	Uncharacterized protein. (608 aa)
	DvirGJ15404	Uncharacterized protein, isoform A. (3480 aa)
	DvirGJ12548	Profilin; Binds to actin and affects the structure of the cytoskeleton. At high concentrations, profilin prevents the polymerization of actin, whereas it enhances it at low concentrations. (126 aa)
	wg	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (472 aa)
	DvirGJ16824	Serine/threonine-protein kinase TOR; Belongs to the PI3/PI4-kinase family. (2471 aa)
	DvirGJ17098	F-actin-capping protein subunit beta; F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments. (276 aa)
	DvirGJ17774	Uncharacterized protein. (710 aa)
	DvirGJ17250	Uncharacterized protein. (5521 aa)
	DvirGJ24208	MFS domain-containing protein. (564 aa)
	DvirGJ23644	Uncharacterized protein, isoform A. (546 aa)
	DvirGJ22970	Uncharacterized protein, isoform C. (4104 aa)
	DvirGJ24290	Uncharacterized protein, isoform A; Belongs to the PI3/PI4-kinase family. (1076 aa)
	DvirGJ23901	Uncharacterized protein. (2626 aa)
	DvirGJ23294	Uncharacterized protein. (2105 aa)
	DvirGJ23974	Fibroblast growth factor receptor. (737 aa)
	DvirGJ24556	Uncharacterized protein. (182 aa)
	DvirGJ23979	AH domain-containing protein. (346 aa)
	DvirGJ24601	Non-specific serine/threonine protein kinase. (705 aa)
	DvirGJ22644	Uncharacterized protein. (839 aa)
	spas	Spastin; ATP-dependent microtubule severing protein. Stimulates microtubule minus-end depolymerization and poleward microtubule flux in the mitotic spindle. Regulates microtubule stability in the neuromuscular junction synapse. Involved in lipid metabolism by regulating the size and distribution of lipid droplets. Involved in axon regeneration by regulating microtubule severing. Belongs to the AAA ATPase family. Spastin subfamily. (769 aa)
	DvirGJ23092	Mothers against decapentaplegic homolog. (769 aa)
	DvirGJ18762	Mothers against decapentaplegic homolog. (489 aa)
	DvirGJ18731	Uncharacterized protein. (1969 aa)
	DvirGJ19008	Uncharacterized protein, isoform A. (343 aa)
	DvirGJ18992	Uncharacterized protein. (401 aa)
	DvirGJ18967	Uncharacterized protein. (364 aa)
	DvirGJ10886	TCTP domain-containing protein; Belongs to the TCTP family. (172 aa)
	DvirGJ10998	Rho-GAP domain-containing protein. (766 aa)
	DvirGJ10601	G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family. (627 aa)
	DvirGJ16530	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (335 aa)
	DvirGJ16462	Uncharacterized protein. (114 aa)
	DvirGJ18140	Mitogen-activated protein kinase. (361 aa)
	DvirGJ15840	5'-3' exoribonuclease 1. (1657 aa)
	DvirGJ15681	Protein kinase domain-containing protein. (681 aa)
	DvirGJ15625	Non-specific serine/threonine protein kinase. (628 aa)
	DvirGJ14364	Uncharacterized protein. (393 aa)
	DvirGJ14161	MACPF domain-containing protein. (367 aa)
	DvirGJ15240	Uncharacterized protein. (603 aa)
	DvirGJ16278	Uncharacterized protein. (383 aa)
	DvirGJ18462	Uncharacterized protein. (615 aa)
	DvirGJ14815	Uncharacterized protein, isoform B. (1091 aa)
	DvirGJ20357	Uncharacterized protein. (621 aa)
	DvirGJ20145	Uncharacterized protein, isoform A. (936 aa)
	DvirGJ19634	Uncharacterized protein, isoform A. (404 aa)
	DvirGJ19213	Uncharacterized protein, isoform B. (1708 aa)
	ey	Eyeless, isoform A. (906 aa)
	DvirGJ15112	Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (551 aa)
	DvirGJ14974	Uncharacterized protein. (577 aa)
	DvirGJ14922	Uncharacterized protein, isoform B. (931 aa)
	DvirGJ18507	Uncharacterized protein. (394 aa)
	DvirGJ18569	PH domain-containing protein. (130 aa)
	DVIR88_6g0069	Uncharacterized protein. (626 aa)
	DVIR88_6g0067	TGF_BETA_2 domain-containing protein. (928 aa)
	DVIR88_6g0054	Uncharacterized protein. (1632 aa)
	DVIR88_6g0032	Uncharacterized protein. (909 aa)

Your Current Organism:

Drosophila virilis

NCBI taxonomy Id: 7244
Other names: D. virilis

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
DVIR88_6g0067	DvirGJ13615	D0Z798	B4LED2	TGF_BETA_2 domain-containing protein.	Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.	0.670
DVIR88_6g0067	DvirGJ15112	D0Z798	B4MF93	TGF_BETA_2 domain-containing protein.	Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.	0.596
DVIR88_6g0067	DvirGJ18762	D0Z798	B4M1Z3	TGF_BETA_2 domain-containing protein.	Mothers against decapentaplegic homolog.	0.503
DVIR88_6g0067	DvirGJ19553	D0Z798	A0A0Q9WLQ5	TGF_BETA_2 domain-containing protein.	Mothers against decapentaplegic homolog.	0.407
DVIR88_6g0067	DvirGJ21177	D0Z798	A0A0Q9WDW8	TGF_BETA_2 domain-containing protein.	Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.	0.719
DVIR88_6g0067	DvirGJ21241	D0Z798	A0A0Q9WFH1	TGF_BETA_2 domain-containing protein.	Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.	0.596
DVIR88_6g0067	DvirGJ23092	D0Z798	B4M0Z7	TGF_BETA_2 domain-containing protein.	Mothers against decapentaplegic homolog.	0.466
DvirGJ10886	DvirGJ24556	B4M470	B4LZB0	TCTP domain-containing protein; Belongs to the TCTP family.	Uncharacterized protein.	0.526
DvirGJ10998	DvirGJ13209	B4M4S7	B4LG76	Rho-GAP domain-containing protein.	Uncharacterized protein.	0.427
DvirGJ11345	DvirGJ20440	B4LBI9	B4LP14	Uncharacterized protein, isoform A.	Uncharacterized protein, isoform C.	0.766
DvirGJ11623	DvirGJ12548	A0A0Q9WWV9	B4LR73	Uncharacterized protein, isoform B.	Profilin; Binds to actin and affects the structure of the cytoskeleton. At high concentrations, profilin prevents the polymerization of actin, whereas it enhances it at low concentrations.	0.672
DvirGJ11623	DvirGJ13271	A0A0Q9WWV9	B4LGZ8	Uncharacterized protein, isoform B.	Uncharacterized protein; Belongs to the actin family.	0.640
DvirGJ11623	DvirGJ17098	A0A0Q9WWV9	B4LT59	Uncharacterized protein, isoform B.	F-actin-capping protein subunit beta; F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments.	0.856
DvirGJ11623	DvirGJ19344	A0A0Q9WWV9	A0A0Q9WN72	Uncharacterized protein, isoform B.	Actin-related protein 2; ATP-binding component of the Arp2/3 complex, a multiprotein complex that mediates actin polymerization upon stimulation by nucleation-promoting factor (NPF). The Arp2/3 complex mediates the formation of branched actin networks in the cytoplasm, providing the force for cell motility. Seems to contact the pointed end of the daughter actin filament.	0.800
DvirGJ12130	DvirGJ16462	B4LG99	B4M7F0	IlGF domain-containing protein.	Uncharacterized protein.	0.582
DvirGJ12130	DvirGJ23294	B4LG99	B4LZ52	IlGF domain-containing protein.	Uncharacterized protein.	0.497
DvirGJ12319	DvirGJ13209	A0A0Q9WI61	B4LG76	Uncharacterized protein, isoform B.	Uncharacterized protein.	0.668
DvirGJ12319	DvirGJ13271	A0A0Q9WI61	B4LGZ8	Uncharacterized protein, isoform B.	Uncharacterized protein; Belongs to the actin family.	0.417
DvirGJ12319	DvirGJ15625	A0A0Q9WI61	B4MAP7	Uncharacterized protein, isoform B.	Non-specific serine/threonine protein kinase.	0.570
DvirGJ12319	DvirGJ17098	A0A0Q9WI61	B4LT59	Uncharacterized protein, isoform B.	F-actin-capping protein subunit beta; F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments.	0.624