127 items (Drosophila virilis) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	Rpd3	Histone deacetylase; Belongs to the histone deacetylase family. HD Type 1 subfamily. (527 aa)
	DvirGJ20377	Uncharacterized protein. (84 aa)
	aop	Aop. (787 aa)
	DvirGJ17232	Serine/threonine-protein phosphatase. (309 aa)
	DvirGJ24548	Uncharacterized protein. (1330 aa)
	DvirGJ23203	Uncharacterized protein. (568 aa)
	DvirGJ23644	Uncharacterized protein, isoform A. (546 aa)
	DvirGJ23560	Uncharacterized protein, isoform A. (666 aa)
	DvirGJ22984	Uncharacterized protein. (1139 aa)
	DvirGJ22945	Uncharacterized protein, isoform C. (2454 aa)
	DvirGJ23510	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (397 aa)
	DvirGJ22869	Uncharacterized protein, isoform A. (712 aa)
	pros	Pros. (1911 aa)
	DvirGJ24420	Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B; Belongs to the phosphatase 2A regulatory subunit B family. (493 aa)
	DvirGJ22775	Uncharacterized protein. (1281 aa)
	DvirGJ23902	Uncharacterized protein. (188 aa)
	DvirGJ23903	Uncharacterized protein. (217 aa)
	DvirGJ23323	Uncharacterized protein. (209 aa)
	DvirGJ23906	Uncharacterized protein. (220 aa)
	DvirGJ23909	Uncharacterized protein. (197 aa)
	DvirGJ23910	Uncharacterized protein. (182 aa)
	DvirGJ23304	Uncharacterized protein. (331 aa)
	DvirGJ24543	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (898 aa)
	DvirGJ23294	Uncharacterized protein. (2105 aa)
	DvirGJ23285	Uncharacterized protein. (566 aa)
	DvirGJ24556	Uncharacterized protein. (182 aa)
	DvirGJ24563	Histone deacetylase; Belongs to the histone deacetylase family. HD Type 1 subfamily. (436 aa)
	DvirGJ22699	Uncharacterized protein. (370 aa)
	DvirGJ22688	MAGE domain-containing protein. (265 aa)
	DvirGJ24001	RIO domain-containing protein. (550 aa)
	DvirGJ23156	Uncharacterized protein, isoform A; Belongs to the small GTPase superfamily. SAR1 family. (193 aa)
	spas	Spastin; ATP-dependent microtubule severing protein. Stimulates microtubule minus-end depolymerization and poleward microtubule flux in the mitotic spindle. Regulates microtubule stability in the neuromuscular junction synapse. Involved in lipid metabolism by regulating the size and distribution of lipid droplets. Involved in axon regeneration by regulating microtubule severing. Belongs to the AAA ATPase family. Spastin subfamily. (769 aa)
	DvirGJ22545	Homeobox domain-containing protein. (641 aa)
	DvirGJ18762	Mothers against decapentaplegic homolog. (489 aa)
	DvirGJ19539	Uncharacterized protein, isoform A. (441 aa)
	DvirGJ18995	BHLH domain-containing protein. (146 aa)
	DvirGJ18967	Uncharacterized protein. (364 aa)
	DvirGJ10657	C2H2-type domain-containing protein. (289 aa)
	DvirGJ10720	Uncharacterized protein. (663 aa)
	DvirGJ10763	Headcase domain-containing protein. (1105 aa)
	DvirGJ16609	RBR-type E3 ubiquitin transferase. (507 aa)
	DvirGJ16443	Uncharacterized protein. (1939 aa)
	DvirGJ16750	SWIB domain-containing protein. (505 aa)
	DvirGJ18207	Uncharacterized protein, isoform B. (566 aa)
	DvirGJ18246	Uncharacterized protein, isoform A. (1046 aa)
	DvirGJ17916	GCM domain-containing protein. (534 aa)
	DvirGJ17906	Uncharacterized protein, isoform A. (572 aa)
	DvirGJ18351	HMG box domain-containing protein. (790 aa)
	DvirGJ15824	DHHA2 domain-containing protein. (429 aa)
	DvirGJ15883	Uncharacterized protein. (2645 aa)
	DvirGJ15920	Uncharacterized protein. (1490 aa)
	DvirGJ15618	FERM domain-containing protein. (638 aa)
	DvirGJ15598	BHLH domain-containing protein. (602 aa)
	DvirGJ15597	Uncharacterized protein, isoform A. (284 aa)
	sc	Scute. (351 aa)
	ac	Achaete. (208 aa)
	DvirGJ15299	Uncharacterized protein. (2757 aa)
	DvirGJ15310	Sulfotransfer_1 domain-containing protein. (373 aa)
	DvirGJ15240	Uncharacterized protein. (603 aa)
	DvirGJ16273	POU domain protein. (597 aa)
	DvirGJ16278	Uncharacterized protein. (383 aa)
	DvirGJ18462	Uncharacterized protein. (615 aa)
	DvirGJ14817	Uncharacterized protein. (1262 aa)
	DvirGJ20569	Uncharacterized protein, isoform C. (1969 aa)
	DvirGJ20145	Uncharacterized protein, isoform A. (936 aa)
	DvirGJ14688	Uncharacterized protein. (2069 aa)
	DvirGJ14974	Uncharacterized protein. (577 aa)
	DvirGJ17687	Uncharacterized protein, isoform B. (738 aa)
	DvirGJ14120	YTH domain-containing protein. (707 aa)
	DvirGJ19651	Uncharacterized protein. (635 aa)
	DVIR88_6g0067	TGF_BETA_2 domain-containing protein. (928 aa)
	Cdc37	Hsp90 co-chaperone Cdc37; Co-chaperone that binds to numerous kinases and promotes their interaction with the Hsp90 complex, resulting in stabilization and promotion of their activity. (399 aa)
	Antp	Antennapedia, isoform B. (380 aa)
	DvirGJ21532	Uncharacterized protein. (8884 aa)
	DvirGJ10360	Protein transport protein SEC23; Component of the coat protein complex II (COPII) which promotes the formation of transport vesicles from the endoplasmic reticulum (ER). The coat has two main functions, the physical deformation of the endoplasmic reticulum membrane into vesicles and the selection of cargo molecules; Belongs to the SEC23/SEC24 family. SEC23 subfamily. (805 aa)
	DvirGJ24712	Uncharacterized protein, isoform D. (2600 aa)
	DvirGJ21177	Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (599 aa)
	DvirGJ23456	Uncharacterized protein, isoform C. (1207 aa)
	DvirGJ20189	Uncharacterized protein, isoform B. (229 aa)
	DvirGJ20621	Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (1107 aa)
	DvirGJ23329	Katanin p60 ATPase-containing subunit A1; Catalytic subunit of a complex which severs microtubules in an ATP-dependent manner. Microtubule severing may promote rapid reorganization of cellular microtubule arrays and the release of microtubules from the centrosome following nucleation. (665 aa)
	DvirGJ19855	Uncharacterized protein, isoform B. (487 aa)
	DvirGJ25775	Uncharacterized protein; Belongs to the protein kinase superfamily. Tyr protein kinase family. (1086 aa)
	DvirGJ16640	Uncharacterized protein, isoform N. (4667 aa)
	DvirGJ20220	Uncharacterized protein, isoform C; Cadherins are calcium-dependent cell adhesion proteins. (3133 aa)
	DvirGJ26454	Uncharacterized protein. (90 aa)
	DvirGJ13251	Uncharacterized protein, isoform B. (381 aa)
	DvirGJ13416	Uncharacterized protein. (2095 aa)
	DvirGJ22639	Uncharacterized protein, isoform E. (681 aa)
	DvirGJ12399	Uncharacterized protein, isoform B. (748 aa)
	DvirGJ14011	Uncharacterized protein, isoform B. (1101 aa)
	DvirGJ11623	Uncharacterized protein, isoform B. (526 aa)
	DvirGJ16288	Uncharacterized protein, isoform B. (1237 aa)
	DvirGJ12563	Uncharacterized protein, isoform A. (1354 aa)
	DvirGJ11263	Serine/threonine-protein kinase RIO1; Belongs to the protein kinase superfamily. RIO-type Ser/Thr kinase family. (586 aa)
	DvirGJ14081	Uncharacterized protein, isoform A. (1247 aa)
	DvirGJ12406	Uncharacterized protein. (775 aa)
	DvirGJ11780	Uncharacterized protein. (1674 aa)
	DvirGJ12331	BHLH domain-containing protein. (390 aa)
	DvirGJ11729	Uncharacterized protein. (713 aa)
	DvirGJ11579	Uncharacterized protein. (575 aa)
	Hsp83	Heat shock protein 83. (716 aa)
	DvirGJ13202	CS domain-containing protein. (334 aa)
	DvirGJ12147	TPR_REGION domain-containing protein. (1187 aa)
	DvirGJ13209	Uncharacterized protein. (192 aa)
	DvirGJ12075	Uncharacterized protein. (589 aa)
	DvirGJ13299	Uncharacterized protein. (485 aa)
	argos	Argos. (482 aa)
	DvirGJ20874	Uncharacterized protein. (764 aa)
	DvirGJ22083	Uncharacterized protein, isoform A. (310 aa)
	DvirGJ20236	Uncharacterized protein. (389 aa)
	DvirGJ22222	Uncharacterized protein; Belongs to the G-protein coupled receptor 2 family. (3654 aa)
	DvirGJ22249	CP2 domain-containing protein. (1257 aa)
	DvirGJ20653	Uncharacterized protein. (413 aa)
	DvirGJ21727	Uncharacterized protein. (231 aa)
	DvirGJ21763	Uncharacterized protein, isoform A; Belongs to the semaphorin family. (778 aa)
	DvirGJ22373	Sema domain-containing protein; Belongs to the semaphorin family. (782 aa)
	DvirGJ22377	Uncharacterized protein, isoform A; Belongs to the semaphorin family. (732 aa)
	DvirGJ20488	Uncharacterized protein. (761 aa)
	Kr	Kruppel. (542 aa)
	DvirGJ20440	Uncharacterized protein, isoform C. (364 aa)
	DvirGJ21907	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (1014 aa)
	DvirGJ21419	Uncharacterized protein. (681 aa)
	DvirGJ12548	Profilin; Binds to actin and affects the structure of the cytoskeleton. At high concentrations, profilin prevents the polymerization of actin, whereas it enhances it at low concentrations. (126 aa)
	DvirGJ16129	Uncharacterized protein. (514 aa)
	DvirGJ16185	Uncharacterized protein. (392 aa)
	DvirGJ11247	Sema domain-containing protein; Belongs to the semaphorin family. (1143 aa)

Your Current Organism:

Drosophila virilis

NCBI taxonomy Id: 7244
Other names: D. virilis

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
Cdc37	DvirGJ22945	Q24740	B4LWM2	Hsp90 co-chaperone Cdc37; Co-chaperone that binds to numerous kinases and promotes their interaction with the Hsp90 complex, resulting in stabilization and promotion of their activity.	Uncharacterized protein, isoform C.	0.696
Cdc37	Hsp83	Q24740	B4LFU3	Hsp90 co-chaperone Cdc37; Co-chaperone that binds to numerous kinases and promotes their interaction with the Hsp90 complex, resulting in stabilization and promotion of their activity.	Heat shock protein 83.	0.991
DVIR88_6g0067	DvirGJ18762	D0Z798	B4M1Z3	TGF_BETA_2 domain-containing protein.	Mothers against decapentaplegic homolog.	0.503
DVIR88_6g0067	DvirGJ20621	D0Z798	A0A0Q9WFW4	TGF_BETA_2 domain-containing protein.	Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily.	0.440
DVIR88_6g0067	DvirGJ21177	D0Z798	A0A0Q9WDW8	TGF_BETA_2 domain-containing protein.	Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.	0.719
DVIR88_6g0067	DvirGJ22945	D0Z798	B4LWM2	TGF_BETA_2 domain-containing protein.	Uncharacterized protein, isoform C.	0.470
DvirGJ10360	DvirGJ20488	A0A0Q9WD23	B4LNF0	Protein transport protein SEC23; Component of the coat protein complex II (COPII) which promotes the formation of transport vesicles from the endoplasmic reticulum (ER). The coat has two main functions, the physical deformation of the endoplasmic reticulum membrane into vesicles and the selection of cargo molecules; Belongs to the SEC23/SEC24 family. SEC23 subfamily.	Uncharacterized protein.	0.734
DvirGJ10360	DvirGJ23156	A0A0Q9WD23	B4M0D6	Protein transport protein SEC23; Component of the coat protein complex II (COPII) which promotes the formation of transport vesicles from the endoplasmic reticulum (ER). The coat has two main functions, the physical deformation of the endoplasmic reticulum membrane into vesicles and the selection of cargo molecules; Belongs to the SEC23/SEC24 family. SEC23 subfamily.	Uncharacterized protein, isoform A; Belongs to the small GTPase superfamily. SAR1 family.	0.996
DvirGJ10657	DvirGJ11579	B4M5W4	B4LFP6	C2H2-type domain-containing protein.	Uncharacterized protein.	0.467
DvirGJ10657	DvirGJ22945	B4M5W4	B4LWM2	C2H2-type domain-containing protein.	Uncharacterized protein, isoform C.	0.427
DvirGJ10763	DvirGJ22639	B4M6F0	A0A0Q9WUB1	Headcase domain-containing protein.	Uncharacterized protein, isoform E.	0.645
DvirGJ11247	DvirGJ14688	B4LSF2	B4MF19	Sema domain-containing protein; Belongs to the semaphorin family.	Uncharacterized protein.	0.843
DvirGJ11247	DvirGJ20569	B4LSF2	B4MEY9	Sema domain-containing protein; Belongs to the semaphorin family.	Uncharacterized protein, isoform C.	0.921
DvirGJ11247	DvirGJ22377	B4LSF2	B4LME9	Sema domain-containing protein; Belongs to the semaphorin family.	Uncharacterized protein, isoform A; Belongs to the semaphorin family.	0.429
DvirGJ11263	DvirGJ24001	B4LCQ2	B4LZL0	Serine/threonine-protein kinase RIO1; Belongs to the protein kinase superfamily. RIO-type Ser/Thr kinase family.	RIO domain-containing protein.	0.934
DvirGJ11579	DvirGJ10657	B4LFP6	B4M5W4	Uncharacterized protein.	C2H2-type domain-containing protein.	0.467
DvirGJ11579	DvirGJ13202	B4LFP6	B4LG60	Uncharacterized protein.	CS domain-containing protein.	0.951
DvirGJ11579	DvirGJ13251	B4LFP6	A0A0Q9WS71	Uncharacterized protein.	Uncharacterized protein, isoform B.	0.648
DvirGJ11579	DvirGJ13299	B4LFP6	B4LH40	Uncharacterized protein.	Uncharacterized protein.	0.467
DvirGJ11579	DvirGJ14081	B4LFP6	B4LCT4	Uncharacterized protein.	Uncharacterized protein, isoform A.	0.645