63 items (Drosophila virilis) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	DvirGJ18778	AP-3 complex subunit delta; Belongs to the adaptor complexes large subunit family. (1063 aa)
	DvirGJ23045	Uncharacterized protein. (3618 aa)
	DvirGJ24657	Uncharacterized protein, isoform A. (229 aa)
	DvirGJ24655	Uncharacterized protein. (207 aa)
	DvirGJ18433	Uncharacterized protein, isoform F. (3497 aa)
	DvirGJ23157	Uncharacterized protein. (181 aa)
	DvirGJ17377	Hepatocyte growth factor-regulated tyrosine kinase substrate; Essential role in endosome membrane invagination and formation of multivesicular bodies, MVBs. Required during gastrulation and appears to regulate early embryonic signaling pathways. Inhibits tyrosine kinase receptor signaling by promoting degradation of the tyrosine-phosphorylated, active receptor, potentially by sorting activated receptors into MVBs. The MVBs are then trafficked to the lysosome where their contents are degraded. (734 aa)
	DvirGJ19497	Uncharacterized protein, isoform A. (690 aa)
	DvirGJ10423	Uncharacterized protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1013 aa)
	DvirGJ17657	Exocyst complex component 2; Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane. Belongs to the SEC5 family. (895 aa)
	DvirGJ12463	Uncharacterized protein. (1207 aa)
	DvirGJ20338	Spatacsin_C domain-containing protein. (1817 aa)
	DvirGJ21351	Uncharacterized protein, isoform C; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (1685 aa)
	DvirGJ19868	Uncharacterized protein, isoform C; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (1936 aa)
	DvirGJ21207	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (294 aa)
	DvirGJ20611	Uncharacterized protein. (147 aa)
	DvirGJ22297	Uncharacterized protein, isoform A; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1809 aa)
	DvirGJ20694	Synaptogyrin. (239 aa)
	DvirGJ22214	Uncharacterized protein. (199 aa)
	DvirGJ20248	Uncharacterized protein, isoform A. (590 aa)
	DvirGJ22020	Kinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (979 aa)
	DvirGJ12627	Uncharacterized protein. (787 aa)
	DvirGJ12149	Uncharacterized protein, isoform A; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1036 aa)
	DvirGJ13704	Uncharacterized protein, isoform A. (561 aa)
	DvirGJ12974	Exocyst complex component 7; Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane. (703 aa)
	DvirGJ12432	Uncharacterized protein. (176 aa)
	DvirGJ14082	Uncharacterized protein, isoform A. (600 aa)
	DvirGJ14081	Uncharacterized protein, isoform A. (1247 aa)
	DvirGJ14036	Uncharacterized protein. (933 aa)
	DvirGJ22626	Uncharacterized protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (1251 aa)
	DvirGJ23318	PH domain-containing protein. (676 aa)
	DvirGJ23727	Exocyst complex component; Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane. (762 aa)
	DvirGJ23499	Uncharacterized protein, isoform A. (214 aa)
	DvirGJ22973	Uncharacterized protein. (135 aa)
	DvirGJ18018	Uncharacterized protein, isoform C. (1254 aa)
	DvirGJ26007	Uncharacterized protein. (198 aa)
	DvirGJ18028	Uncharacterized protein, isoform B; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1442 aa)
	DvirGJ26878	Uncharacterized protein. (228 aa)
	DvirGJ10920	Uncharacterized protein, isoform H. (803 aa)
	DvirGJ15580	Uncharacterized protein, isoform C; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (908 aa)
	DvirGJ15999	Uncharacterized protein, isoform B; Belongs to the STXBP/unc-18/SEC1 family. (602 aa)
	DvirGJ12726	Uncharacterized protein, isoform B. (508 aa)
	DVIR88_6g0043	Uncharacterized protein. (3494 aa)
	DvirGJ15472	Uncharacterized protein, isoform C. (4643 aa)
	DvirGJ15060	Uncharacterized protein. (738 aa)
	DvirGJ16193	Uncharacterized protein, isoform A; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (2126 aa)
	DvirGJ15287	Uncharacterized protein. (618 aa)
	DvirGJ14160	Uncharacterized protein, isoform D; Belongs to the MAGUK family. (906 aa)
	DvirGJ14202	Uncharacterized protein. (710 aa)
	DvirGJ14530	Uncharacterized protein, isoform A; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1296 aa)
	DvirGJ16030	Uncharacterized protein. (226 aa)
	DvirGJ13251	Uncharacterized protein, isoform B. (381 aa)
	DvirGJ23024	Uncharacterized protein, isoform D; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1280 aa)
	DvirGJ23889	Uncharacterized protein, isoform B. (1372 aa)
	DvirGJ15631	Uncharacterized protein, isoform C; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (3061 aa)
	DvirGJ15856	Uncharacterized protein. (348 aa)
	DvirGJ15782	Uncharacterized protein, isoform A; Belongs to the mitochondrial carrier (TC 2.A.29) family. (299 aa)
	DvirGJ16550	Uncharacterized protein; Belongs to the PI3/PI4-kinase family. (3218 aa)
	DvirGJ10720	Uncharacterized protein. (663 aa)
	DvirGJ10684	BRO1 domain-containing protein. (835 aa)
	DvirGJ18921	Uncharacterized protein, isoform A. (845 aa)
	DvirGJ18922	Uncharacterized protein; Belongs to the Stoned B family. (1274 aa)
	DvirGJ19473	Uncharacterized protein, isoform A. (201 aa)

Your Current Organism:

Drosophila virilis

NCBI taxonomy Id: 7244
Other names: D. virilis

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structured XML interaction data, according to the 'PSI-MI' data standard

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
DVIR88_6g0043	DvirGJ12463	D0Z7E8	B4LR86	Uncharacterized protein.	Uncharacterized protein.	0.771
DVIR88_6g0043	DvirGJ14160	D0Z7E8	B4MC57	Uncharacterized protein.	Uncharacterized protein, isoform D; Belongs to the MAGUK family.	0.945
DVIR88_6g0043	DvirGJ15999	D0Z7E8	A0A0Q9WEV9	Uncharacterized protein.	Uncharacterized protein, isoform B; Belongs to the STXBP/unc-18/SEC1 family.	0.770
DvirGJ10684	DvirGJ17377	B4M616	B4LUT9	BRO1 domain-containing protein.	Hepatocyte growth factor-regulated tyrosine kinase substrate; Essential role in endosome membrane invagination and formation of multivesicular bodies, MVBs. Required during gastrulation and appears to regulate early embryonic signaling pathways. Inhibits tyrosine kinase receptor signaling by promoting degradation of the tyrosine-phosphorylated, active receptor, potentially by sorting activated receptors into MVBs. The MVBs are then trafficked to the lysosome where their contents are degraded.	0.403
DvirGJ10684	DvirGJ22214	B4M616	B4LKM1	BRO1 domain-containing protein.	Uncharacterized protein.	0.661
DvirGJ10920	DvirGJ15580	A0A0Q9WC16	A0A0Q9WDF8	Uncharacterized protein, isoform H.	Uncharacterized protein, isoform C; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family.	0.597
DvirGJ10920	DvirGJ18778	A0A0Q9WC16	B4M1W3	Uncharacterized protein, isoform H.	AP-3 complex subunit delta; Belongs to the adaptor complexes large subunit family.	0.632
DvirGJ10920	DvirGJ18922	A0A0Q9WC16	B4M3M6	Uncharacterized protein, isoform H.	Uncharacterized protein; Belongs to the Stoned B family.	0.807
DvirGJ12149	DvirGJ14160	B4LG69	B4MC57	Uncharacterized protein, isoform A; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.	Uncharacterized protein, isoform D; Belongs to the MAGUK family.	0.558
DvirGJ12463	DVIR88_6g0043	B4LR86	D0Z7E8	Uncharacterized protein.	Uncharacterized protein.	0.771
DvirGJ12463	DvirGJ14160	B4LR86	B4MC57	Uncharacterized protein.	Uncharacterized protein, isoform D; Belongs to the MAGUK family.	0.989
DvirGJ12463	DvirGJ15999	B4LR86	A0A0Q9WEV9	Uncharacterized protein.	Uncharacterized protein, isoform B; Belongs to the STXBP/unc-18/SEC1 family.	0.668
DvirGJ12463	DvirGJ18433	B4LR86	A0A0Q9WL55	Uncharacterized protein.	Uncharacterized protein, isoform F.	0.771
DvirGJ12463	DvirGJ21351	B4LR86	B4LP90	Uncharacterized protein.	Uncharacterized protein, isoform C; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.	0.448
DvirGJ12974	DvirGJ14202	B4LDS3	B4MBY6	Exocyst complex component 7; Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane.	Uncharacterized protein.	0.998
DvirGJ12974	DvirGJ15060	B4LDS3	B4MFJ1	Exocyst complex component 7; Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane.	Uncharacterized protein.	0.999
DvirGJ12974	DvirGJ15999	B4LDS3	A0A0Q9WEV9	Exocyst complex component 7; Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane.	Uncharacterized protein, isoform B; Belongs to the STXBP/unc-18/SEC1 family.	0.793
DvirGJ12974	DvirGJ17657	B4LDS3	B4LSG5	Exocyst complex component 7; Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane.	Exocyst complex component 2; Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane. Belongs to the SEC5 family.	0.999
DvirGJ12974	DvirGJ18028	B4LDS3	A0A0Q9WA14	Exocyst complex component 7; Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane.	Uncharacterized protein, isoform B; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.	0.429
DvirGJ12974	DvirGJ22297	B4LDS3	B4LLC5	Exocyst complex component 7; Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane.	Uncharacterized protein, isoform A; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.	0.448