100 items (Drosophila virilis) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	DvirGJ22623	G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family. (422 aa)
	DvirGJ23131	Uncharacterized protein. (213 aa)
	DvirGJ18884	RHD domain-containing protein. (1254 aa)
	DvirGJ19315	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (1073 aa)
	DvirGJ19169	Uncharacterized protein. (529 aa)
	DvirGJ19175	Uncharacterized protein. (148 aa)
	DvirGJ19176	Uncharacterized protein, isoform A. (187 aa)
	DvirGJ10932	Uncharacterized protein, isoform A. (471 aa)
	DvirGJ10998	Rho-GAP domain-containing protein. (766 aa)
	DvirGJ11108	Uncharacterized protein. (279 aa)
	DvirGJ10658	Uncharacterized protein, isoform A; Belongs to the protein kinase superfamily. (467 aa)
	DvirGJ16821	Uncharacterized protein. (356 aa)
	DvirGJ16615	Uncharacterized protein, isoform A; Belongs to the band 7/mec-2 family. Flotillin subfamily. (405 aa)
	DvirGJ18054	Uncharacterized protein. (238 aa)
	DvirGJ17849	BHLH domain-containing protein. (339 aa)
	DvirGJ15815	Uncharacterized protein. (204 aa)
	DvirGJ15757	Uncharacterized protein. (751 aa)
	DvirGJ15915	LLGL domain-containing protein. (1109 aa)
	DvirGJ16012	Uncharacterized protein, isoform A; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family. (379 aa)
	DvirGJ16030	Uncharacterized protein. (226 aa)
	DvirGJ16039	Uncharacterized protein, isoform A. (983 aa)
	DVIR88_6g0053	Rhomboid domain-containing protein. (1531 aa)
	DVIR88_6g0001	MHD1 domain-containing protein. (425 aa)
	DvirGJ14117	Uncharacterized protein; Belongs to the band 7/mec-2 family. Flotillin subfamily. (110 aa)
	DvirGJ15086	Uncharacterized protein, isoform A. (287 aa)
	DvirGJ15037	Uncharacterized protein, isoform D. (792 aa)
	DvirGJ12969	Uncharacterized protein. (416 aa)
	DvirGJ12217	Uncharacterized protein, isoform A. (1545 aa)
	DvirGJ14874	Uncharacterized protein. (202 aa)
	DvirGJ14846	C2H2-type domain-containing protein. (365 aa)
	DvirGJ18949	Uncharacterized protein. (258 aa)
	DvirGJ16115	Uncharacterized protein. (635 aa)
	DvirGJ15264	Septin-type G domain-containing protein; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family. (447 aa)
	DvirGJ14149	PX domain-containing protein. (167 aa)
	DvirGJ14160	Uncharacterized protein, isoform D; Belongs to the MAGUK family. (906 aa)
	DvirGJ14207	Rab-GAP TBC domain-containing protein. (294 aa)
	DvirGJ14443	Uncharacterized protein. (205 aa)
	DvirGJ20043	Uncharacterized protein, isoform B. (170 aa)
	DvirGJ16823	Uncharacterized protein, isoform B. (2843 aa)
	DvirGJ14459	Uncharacterized protein, isoform F. (143 aa)
	DvirGJ18738	Uncharacterized protein, isoform U. (1952 aa)
	DvirGJ10360	Protein transport protein SEC23; Component of the coat protein complex II (COPII) which promotes the formation of transport vesicles from the endoplasmic reticulum (ER). The coat has two main functions, the physical deformation of the endoplasmic reticulum membrane into vesicles and the selection of cargo molecules; Belongs to the SEC23/SEC24 family. SEC23 subfamily. (805 aa)
	DvirGJ15962	Uncharacterized protein, isoform B. (256 aa)
	DvirGJ23383	Non-specific serine/threonine protein kinase. (695 aa)
	DvirGJ20097	Uncharacterized protein, isoform B. (276 aa)
	DvirGJ22727	Uncharacterized protein, isoform P. (3636 aa)
	DvirGJ13629	MFS domain-containing protein; Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. (1642 aa)
	DvirGJ14870	Uncharacterized protein, isoform B. (676 aa)
	DvirGJ14122	Uncharacterized protein, isoform B. (1146 aa)
	DvirGJ12042	Uncharacterized protein. (2049 aa)
	DvirGJ26194	Rhomboid domain-containing protein. (1531 aa)
	DvirGJ17721	Uncharacterized protein, isoform C. (437 aa)
	DvirGJ16275	Uncharacterized protein, isoform C. (566 aa)
	DvirGJ17344	Uncharacterized protein, isoform K. (606 aa)
	DvirGJ22702	Uncharacterized protein, isoform B. (2849 aa)
	DvirGJ23024	Uncharacterized protein, isoform D; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1280 aa)
	DvirGJ24302	Uncharacterized protein, isoform B. (1248 aa)
	DvirGJ18403	Uncharacterized protein, isoform F. (152 aa)
	DvirGJ12600	Uncharacterized protein; Belongs to the peptidase S1 family. (2186 aa)
	DvirGJ12825	Uncharacterized protein. (84 aa)
	DvirGJ13392	Uncharacterized protein, isoform A. (1349 aa)
	DvirGJ13999	Uncharacterized protein. (207 aa)
	DvirGJ12849	Sorting nexin; Belongs to the sorting nexin family. (563 aa)
	wls	Protein wntless; A segment polarity gene required for wingless (wg)-dependent patterning processes, acting in both wg-sending cells and wg-target cells. In non-neuronal cells wls directs wg secretion. The wls traffic loop encompasses the Golgi, the cell surface, an endocytic compartment and a retrograde route leading back to the Golgi, and involves clathrin-mediated endocytosis and the retromer complex (a conserved protein complex consisting of Vps35 and Vps26). In neuronal cells (the larval motorneuron NMJ), the wg signal moves across the synapse via the release of wls-containing exos [...] (562 aa)
	DvirGJ12917	Rhomboid domain-containing protein; Belongs to the peptidase S54 family. (314 aa)
	DvirGJ12943	Uncharacterized protein. (184 aa)
	DvirGJ11811	Uncharacterized protein. (1718 aa)
	DvirGJ13576	Palmitoyltransferase; Belongs to the DHHC palmitoyltransferase family. (657 aa)
	DvirGJ11619	Uncharacterized protein, isoform A. (600 aa)
	DvirGJ12178	Fmp27_GFWDK domain-containing protein. (2291 aa)
	DvirGJ13772	Uncharacterized protein, isoform A. (308 aa)
	DvirGJ13283	Uncharacterized protein. (358 aa)
	DvirGJ13314	Uncharacterized protein, isoform A. (1158 aa)
	DvirGJ21446	Uncharacterized protein. (261 aa)
	DvirGJ21482	t-SNARE coiled-coil homology domain-containing protein. (280 aa)
	DvirGJ20296	Uncharacterized protein. (976 aa)
	DvirGJ22344	Vacuolar protein sorting-associated protein 35; Plays a role in vesicular protein sorting. (818 aa)
	DvirGJ21776	Uncharacterized protein, isoform C. (1197 aa)
	DvirGJ22394	Cyclic nucleotide-binding domain-containing protein. (1361 aa)
	DvirGJ21051	tRNA-binding domain-containing protein. (311 aa)
	gbb	Gbb. (436 aa)
	DvirGJ22481	DUF3456 domain-containing protein. (193 aa)
	DvirGJ21900	ADF-H domain-containing protein; Belongs to the actin-binding proteins ADF family. (148 aa)
	DvirGJ22369	Uncharacterized protein. (1207 aa)
	DvirGJ17702	Uncharacterized protein. (501 aa)
	DvirGJ10738	Uncharacterized protein. (387 aa)
	DvirGJ10705	Uncharacterized protein. (919 aa)
	DvirGJ17271	Uncharacterized protein. (800 aa)
	DvirGJ24006	Uncharacterized protein. (502 aa)
	DvirGJ23686	Uncharacterized protein. (160 aa)
	DvirGJ17377	Hepatocyte growth factor-regulated tyrosine kinase substrate; Essential role in endosome membrane invagination and formation of multivesicular bodies, MVBs. Required during gastrulation and appears to regulate early embryonic signaling pathways. Inhibits tyrosine kinase receptor signaling by promoting degradation of the tyrosine-phosphorylated, active receptor, potentially by sorting activated receptors into MVBs. The MVBs are then trafficked to the lysosome where their contents are degraded. (734 aa)
	DvirGJ23460	SNAPIN protein homolog; Component of the biogenesis of lysosome-related organelles complex-1 (BLOC-1) involved in pigment granule biogenesis. (136 aa)
	DvirGJ17415	Uncharacterized protein, isoform A. (467 aa)
	DvirGJ17416	Uncharacterized protein, isoform A. (248 aa)
	DvirGJ24267	Uncharacterized protein. (858 aa)
	DvirGJ22861	Uncharacterized protein. (584 aa)
	DvirGJ22763	Uncharacterized protein. (335 aa)
	DvirGJ23294	Uncharacterized protein. (2105 aa)
	DvirGJ23289	Uncharacterized protein, isoform A. (276 aa)
	DvirGJ24663	Uncharacterized protein, isoform A. (429 aa)

Your Current Organism:

Drosophila virilis

NCBI taxonomy Id: 7244
Other names: D. virilis

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
DvirGJ10360	DvirGJ10658	A0A0Q9WD23	B4M5W6	Protein transport protein SEC23; Component of the coat protein complex II (COPII) which promotes the formation of transport vesicles from the endoplasmic reticulum (ER). The coat has two main functions, the physical deformation of the endoplasmic reticulum membrane into vesicles and the selection of cargo molecules; Belongs to the SEC23/SEC24 family. SEC23 subfamily.	Uncharacterized protein, isoform A; Belongs to the protein kinase superfamily.	0.422
DvirGJ10360	DvirGJ14149	A0A0Q9WD23	B4MC73	Protein transport protein SEC23; Component of the coat protein complex II (COPII) which promotes the formation of transport vesicles from the endoplasmic reticulum (ER). The coat has two main functions, the physical deformation of the endoplasmic reticulum membrane into vesicles and the selection of cargo molecules; Belongs to the SEC23/SEC24 family. SEC23 subfamily.	PX domain-containing protein.	0.443
DvirGJ10360	DvirGJ14443	A0A0Q9WD23	B4MBH0	Protein transport protein SEC23; Component of the coat protein complex II (COPII) which promotes the formation of transport vesicles from the endoplasmic reticulum (ER). The coat has two main functions, the physical deformation of the endoplasmic reticulum membrane into vesicles and the selection of cargo molecules; Belongs to the SEC23/SEC24 family. SEC23 subfamily.	Uncharacterized protein.	0.726
DvirGJ10360	DvirGJ14874	A0A0Q9WD23	B4MES9	Protein transport protein SEC23; Component of the coat protein complex II (COPII) which promotes the formation of transport vesicles from the endoplasmic reticulum (ER). The coat has two main functions, the physical deformation of the endoplasmic reticulum membrane into vesicles and the selection of cargo molecules; Belongs to the SEC23/SEC24 family. SEC23 subfamily.	Uncharacterized protein.	0.726
DvirGJ10360	DvirGJ21446	A0A0Q9WD23	B4LIL1	Protein transport protein SEC23; Component of the coat protein complex II (COPII) which promotes the formation of transport vesicles from the endoplasmic reticulum (ER). The coat has two main functions, the physical deformation of the endoplasmic reticulum membrane into vesicles and the selection of cargo molecules; Belongs to the SEC23/SEC24 family. SEC23 subfamily.	Uncharacterized protein.	0.422
DvirGJ10360	DvirGJ22369	A0A0Q9WD23	B4LQM1	Protein transport protein SEC23; Component of the coat protein complex II (COPII) which promotes the formation of transport vesicles from the endoplasmic reticulum (ER). The coat has two main functions, the physical deformation of the endoplasmic reticulum membrane into vesicles and the selection of cargo molecules; Belongs to the SEC23/SEC24 family. SEC23 subfamily.	Uncharacterized protein.	0.999
DvirGJ10658	DvirGJ10360	B4M5W6	A0A0Q9WD23	Uncharacterized protein, isoform A; Belongs to the protein kinase superfamily.	Protein transport protein SEC23; Component of the coat protein complex II (COPII) which promotes the formation of transport vesicles from the endoplasmic reticulum (ER). The coat has two main functions, the physical deformation of the endoplasmic reticulum membrane into vesicles and the selection of cargo molecules; Belongs to the SEC23/SEC24 family. SEC23 subfamily.	0.422
DvirGJ10705	DvirGJ16823	B4LT51	A0A0Q9W7P8	Uncharacterized protein.	Uncharacterized protein, isoform B.	0.455
DvirGJ10932	DvirGJ11619	B4M4G2	B4LFJ5	Uncharacterized protein, isoform A.	Uncharacterized protein, isoform A.	0.496
DvirGJ10932	DvirGJ13392	B4M4G2	B4LBB1	Uncharacterized protein, isoform A.	Uncharacterized protein, isoform A.	0.412
DvirGJ10932	DvirGJ14160	B4M4G2	B4MC57	Uncharacterized protein, isoform A.	Uncharacterized protein, isoform D; Belongs to the MAGUK family.	0.624
DvirGJ10932	DvirGJ15915	B4M4G2	B4MAH5	Uncharacterized protein, isoform A.	LLGL domain-containing protein.	0.443
DvirGJ10932	DvirGJ17415	B4M4G2	B4LV77	Uncharacterized protein, isoform A.	Uncharacterized protein, isoform A.	0.869
DvirGJ10998	DvirGJ15962	B4M4S7	A0A0Q9WDC0	Rho-GAP domain-containing protein.	Uncharacterized protein, isoform B.	0.427
DvirGJ11619	DvirGJ10932	B4LFJ5	B4M4G2	Uncharacterized protein, isoform A.	Uncharacterized protein, isoform A.	0.496
DvirGJ11619	DvirGJ13392	B4LFJ5	B4LBB1	Uncharacterized protein, isoform A.	Uncharacterized protein, isoform A.	0.432
DvirGJ11619	DvirGJ14160	B4LFJ5	B4MC57	Uncharacterized protein, isoform A.	Uncharacterized protein, isoform D; Belongs to the MAGUK family.	0.624
DvirGJ11619	DvirGJ17415	B4LFJ5	B4LV77	Uncharacterized protein, isoform A.	Uncharacterized protein, isoform A.	0.543
DvirGJ11811	DvirGJ12943	B4LDN0	B4LDE8	Uncharacterized protein.	Uncharacterized protein.	0.449
DvirGJ11811	DvirGJ15962	B4LDN0	A0A0Q9WDC0	Uncharacterized protein.	Uncharacterized protein, isoform B.	0.482