58 items (Drosophila virilis) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	DvirGJ20577	C2 domain-containing protein. (1335 aa)
	DvirGJ21820	Uncharacterized protein. (1065 aa)
	DvirGJ21016	Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (682 aa)
	DvirGJ11619	Uncharacterized protein, isoform A. (600 aa)
	DvirGJ21015	Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (698 aa)
	DvirGJ17702	Uncharacterized protein. (501 aa)
	DvirGJ17415	Uncharacterized protein, isoform A. (467 aa)
	DvirGJ23366	Uncharacterized protein, isoform D. (857 aa)
	DvirGJ12273	Uncharacterized protein, isoform A. (962 aa)
	DvirGJ11688	Uncharacterized protein. (1213 aa)
	DvirGJ11781	Uncharacterized protein. (2142 aa)
	DvirGJ12993	J domain-containing protein. (764 aa)
	DvirGJ23976	Uncharacterized protein, isoform E. (2785 aa)
	DvirGJ12527	Uncharacterized protein, isoform A. (1357 aa)
	DvirGJ13392	Uncharacterized protein, isoform A. (1349 aa)
	DvirGJ24460	Uncharacterized protein, isoform C. (1864 aa)
	DvirGJ24290	Uncharacterized protein, isoform A; Belongs to the PI3/PI4-kinase family. (1076 aa)
	DvirGJ24168	Uncharacterized protein; Belongs to the DOCK family. (2197 aa)
	DvirGJ22970	Uncharacterized protein, isoform C. (4104 aa)
	DvirGJ22930	Uncharacterized protein, isoform A. (962 aa)
	DvirGJ26586	C2 domain-containing protein. (98 aa)
	DvirGJ11253	Uncharacterized protein, isoform F; Belongs to the PI3/PI4-kinase family. (1936 aa)
	DvirGJ16211	Uncharacterized protein, isoform A; Belongs to the DOCK family. (2055 aa)
	DvirGJ12217	Uncharacterized protein, isoform A. (1545 aa)
	DvirGJ12969	Uncharacterized protein. (416 aa)
	DVIR88_6g0043	Uncharacterized protein. (3494 aa)
	small-wing	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1231 aa)
	DvirGJ18433	Uncharacterized protein, isoform F. (3497 aa)
	DvirGJ17528	Uncharacterized protein, isoform C. (597 aa)
	DvirGJ11527	Uncharacterized protein, isoform B. (1113 aa)
	DvirGJ17604	Uncharacterized protein, isoform O; Belongs to the DOCK family. (2279 aa)
	DvirGJ16725	Uncharacterized protein, isoform C. (1458 aa)
	DvirGJ14122	Uncharacterized protein, isoform B. (1146 aa)
	DvirGJ14870	Uncharacterized protein, isoform B. (676 aa)
	DvirGJ22588	Uncharacterized protein, isoform B; Belongs to the DOCK family. (2009 aa)
	DvirGJ10428	Uncharacterized protein. (628 aa)
	DvirGJ15757	Uncharacterized protein. (751 aa)
	DvirGJ16831	Uncharacterized protein, isoform C. (2079 aa)
	DvirGJ15727	Uncharacterized protein. (954 aa)
	DvirGJ14155	Uncharacterized protein. (1212 aa)
	DvirGJ22884	Uncharacterized protein. (2179 aa)
	DvirGJ18887	Uncharacterized protein, isoform B. (830 aa)
	DvirGJ10533	Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (740 aa)
	DvirGJ23620	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1279 aa)
	DvirGJ10553	Uncharacterized protein, isoform B. (839 aa)
	DvirGJ17032	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1094 aa)
	DvirGJ16823	Uncharacterized protein, isoform B. (2843 aa)
	DvirGJ19770	Uncharacterized protein. (923 aa)
	DvirGJ20275	Uncharacterized protein, isoform D. (1370 aa)
	DvirGJ23414	C2 domain-containing protein. (1597 aa)
	DvirGJ10932	Uncharacterized protein, isoform A. (471 aa)
	DvirGJ19018	PH domain-containing protein. (1274 aa)
	Kibra	Protein kibra; Regulator of the Hippo/SWH (Sav/Wts/Hpo) signaling pathway, a signaling pathway that plays a pivotal role in organ size control and tumor suppression by restricting proliferation and promoting apoptosis. The core of this pathway is composed of a kinase cascade wherein Hippo (Hpo), in complex with its regulatory protein Salvador (Sav), phosphorylates and activates Warts (Wts) in complex with its regulatory protein Mats, which in turn phosphorylates and inactivates the Yorkie (Yki) oncoprotein. Kibra acts synergistically along with Ex and Mer to regulate the Hippo signalin [...] (1276 aa)
	DvirGJ13263	Uncharacterized protein, isoform A. (485 aa)
	DvirGJ23476	DUF3668 domain-containing protein. (1471 aa)
	DvirGJ20296	Uncharacterized protein. (976 aa)
	DvirGJ12291	Uncharacterized protein, isoform B. (1635 aa)
	DvirGJ22348	Phosphatidylinositol 3-kinase catalytic subunit type 3. (943 aa)

Your Current Organism:

Drosophila virilis

NCBI taxonomy Id: 7244
Other names: D. virilis

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structured XML interaction data, according to the 'PSI-MI' data standard

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a flat-file format describing the coordinates and colors of nodes in the network

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

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a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
DVIR88_6g0043	DvirGJ10932	D0Z7E8	B4M4G2	Uncharacterized protein.	Uncharacterized protein, isoform A.	0.511
DVIR88_6g0043	DvirGJ12969	D0Z7E8	B4MEY0	Uncharacterized protein.	Uncharacterized protein.	0.420
DVIR88_6g0043	DvirGJ13392	D0Z7E8	B4LBB1	Uncharacterized protein.	Uncharacterized protein, isoform A.	0.988
DVIR88_6g0043	DvirGJ15757	D0Z7E8	B4MA15	Uncharacterized protein.	Uncharacterized protein.	0.464
DVIR88_6g0043	DvirGJ16823	D0Z7E8	A0A0Q9W7P8	Uncharacterized protein.	Uncharacterized protein, isoform B.	0.487
DVIR88_6g0043	DvirGJ17415	D0Z7E8	B4LV77	Uncharacterized protein.	Uncharacterized protein, isoform A.	0.763
DVIR88_6g0043	DvirGJ23976	D0Z7E8	B4LZH2	Uncharacterized protein.	Uncharacterized protein, isoform E.	0.999
DvirGJ10428	DvirGJ13392	B4M6A0	B4LBB1	Uncharacterized protein.	Uncharacterized protein, isoform A.	0.457
DvirGJ10428	DvirGJ23366	B4M6A0	A0A0Q9WRW3	Uncharacterized protein.	Uncharacterized protein, isoform D.	0.405
DvirGJ10428	DvirGJ23976	B4M6A0	B4LZH2	Uncharacterized protein.	Uncharacterized protein, isoform E.	0.715
DvirGJ10533	DvirGJ15727	A0A0Q9W9V5	B4MA59	Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily.	Uncharacterized protein.	0.545
DvirGJ10533	DvirGJ17032	A0A0Q9W9V5	A0A0Q9W852	Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily.	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes.	0.558
DvirGJ10533	DvirGJ21015	A0A0Q9W9V5	B4LP69	Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily.	Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily.	0.577
DvirGJ10533	DvirGJ21016	A0A0Q9W9V5	B4LP68	Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily.	Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily.	0.572
DvirGJ10533	small-wing	A0A0Q9W9V5	Q86RA6	Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily.	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades.	0.704
DvirGJ10932	DVIR88_6g0043	B4M4G2	D0Z7E8	Uncharacterized protein, isoform A.	Uncharacterized protein.	0.511
DvirGJ10932	DvirGJ11619	B4M4G2	B4LFJ5	Uncharacterized protein, isoform A.	Uncharacterized protein, isoform A.	0.496
DvirGJ10932	DvirGJ12291	B4M4G2	A0A0Q9WTK5	Uncharacterized protein, isoform A.	Uncharacterized protein, isoform B.	0.571
DvirGJ10932	DvirGJ13392	B4M4G2	B4LBB1	Uncharacterized protein, isoform A.	Uncharacterized protein, isoform A.	0.412
DvirGJ10932	DvirGJ17415	B4M4G2	B4LV77	Uncharacterized protein, isoform A.	Uncharacterized protein, isoform A.	0.869