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DvirGJ13537 DvirGJ13537 DvirGJ11957 DvirGJ11957 DvirGJ12824 DvirGJ12824 DvirGJ24495 DvirGJ24495 DvirGJ24091 DvirGJ24091 DvirGJ18875 DvirGJ18875 DvirGJ22301 DvirGJ22301 DvirGJ12755 DvirGJ12755 DvirGJ22286 DvirGJ22286 DvirGJ22212 DvirGJ22212 DvirGJ15580 DvirGJ15580 DvirGJ15962 DvirGJ15962 DvirGJ23546 DvirGJ23546 DvirGJ22091 DvirGJ22091 DvirGJ21536 DvirGJ21536 DvirGJ14973 DvirGJ14973 DvirGJ19602 DvirGJ19602 DvirGJ21658 DvirGJ21658 DvirGJ14876 DvirGJ14876 DvirGJ17556 DvirGJ17556 DvirGJ17887 DvirGJ17887 DvirGJ15357 DvirGJ15357 DvirGJ15264 DvirGJ15264 DvirGJ19676 DvirGJ19676 DvirGJ11156 DvirGJ11156 DvirGJ15559 DvirGJ15559 DvirGJ16013 DvirGJ16013 DvirGJ16012 DvirGJ16012 DvirGJ18257 DvirGJ18257 DvirGJ17988 DvirGJ17988 DvirGJ18016 DvirGJ18016 DvirGJ16931 DvirGJ16931 DvirGJ16566 DvirGJ16566 DvirGJ10465 DvirGJ10465 DvirGJ11110 DvirGJ11110 DvirGJ10964 DvirGJ10964 DvirGJ10958 DvirGJ10958 mRRF2 mRRF2 DvirGJ18919 DvirGJ18919 DvirGJ19155 DvirGJ19155 DvirGJ19096 DvirGJ19096 DvirGJ18652 DvirGJ18652 DvirGJ18826 DvirGJ18826 DvirGJ24163 DvirGJ24163 DvirGJ23103 DvirGJ23103 DvirGJ17947 DvirGJ17947 DvirGJ24092 DvirGJ24092 DvirGJ22573 DvirGJ22573 DvirGJ23156 DvirGJ23156 DvirGJ24575 DvirGJ24575 DvirGJ24568 DvirGJ24568 DvirGJ24556 DvirGJ24556 DvirGJ23270 DvirGJ23270 DvirGJ22744 DvirGJ22744 DvirGJ24514 DvirGJ24514 DvirGJ23879 DvirGJ23879 DvirGJ23847 DvirGJ23847 Ras85D Ras85D DvirGJ23413 DvirGJ23413 DvirGJ24357 DvirGJ24357 DvirGJ24294 DvirGJ24294 GJ24271 GJ24271 DvirGJ23644 DvirGJ23644 DvirGJ23573 DvirGJ23573 DvirGJ17776 DvirGJ17776 mEFG1 mEFG1 DvirGJ17614 DvirGJ17614 DvirGJ16007 DvirGJ16007 DvirGJ20899 DvirGJ20899 DvirGJ20446 DvirGJ20446 DvirGJ21886 DvirGJ21886 DvirGJ20466 DvirGJ20466 DvirGJ20468 DvirGJ20468 DvirGJ22341 DvirGJ22341 DvirGJ22328 DvirGJ22328 DvirGJ22327 DvirGJ22327 DvirGJ20064 DvirGJ20064 DvirGJ21698 DvirGJ21698 DvirGJ20079 DvirGJ20079 DvirGJ21592 DvirGJ21592 DvirGJ12031 DvirGJ12031 DvirGJ13838 DvirGJ13838 DvirGJ13209 DvirGJ13209 DvirGJ12166 DvirGJ12166 DvirGJ13160 DvirGJ13160 DvirGJ12241 DvirGJ12241 DvirGJ12256 DvirGJ12256 DvirGJ13575 DvirGJ13575 DvirGJ12360 DvirGJ12360 DvirGJ13559 DvirGJ13559 DvirGJ12943 DvirGJ12943 DvirGJ12878 DvirGJ12878
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
DvirGJ13537Uncharacterized protein. (787 aa)
DvirGJ11957Succinate--CoA ligase [GDP-forming] subunit beta, mitochondrial; GTP-specific succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. (420 aa)
DvirGJ12824Uncharacterized protein. (192 aa)
DvirGJ24495Tubulin beta chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (456 aa)
DvirGJ24091Uncharacterized protein, isoform B; Belongs to the small GTPase superfamily. Arf family. (199 aa)
DvirGJ18875Uncharacterized protein. (648 aa)
DvirGJ22301Uncharacterized protein, isoform D; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (971 aa)
DvirGJ12755Uncharacterized protein, isoform B. (266 aa)
DvirGJ22286Uncharacterized protein, isoform C. (210 aa)
DvirGJ22212Uncharacterized protein, isoform C. (354 aa)
DvirGJ15580Uncharacterized protein, isoform C; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (908 aa)
DvirGJ15962Uncharacterized protein, isoform B. (256 aa)
DvirGJ23546Uncharacterized protein, isoform B; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (747 aa)
DvirGJ22091Uncharacterized protein, isoform B. (445 aa)
DvirGJ21536Uncharacterized protein, isoform B. (769 aa)
DvirGJ14973Uncharacterized protein, isoform A; Belongs to the small GTPase superfamily. Arf family. (175 aa)
DvirGJ19602Uncharacterized protein; Belongs to the small GTPase superfamily. Arf family. (180 aa)
DvirGJ21658Uncharacterized protein, isoform A. (307 aa)
DvirGJ14876Uncharacterized protein. (200 aa)
DvirGJ17556Uncharacterized protein. (273 aa)
DvirGJ17887Elongation factor 1-alpha; This protein promotes the GTP-dependent binding of aminoacyl- tRNA to the A-site of ribosomes during protein biosynthesis. (463 aa)
DvirGJ15357GPN-loop GTPase; Small GTPase required for proper nuclear import of RNA polymerase II (RNAPII). May act at an RNAP assembly step prior to nuclear import. (399 aa)
DvirGJ15264Septin-type G domain-containing protein; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family. (447 aa)
DvirGJ19676Elongation factor Tu; This protein promotes the GTP-dependent binding of aminoacyl- tRNA to the A-site of ribosomes during protein biosynthesis. (487 aa)
DvirGJ11156Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (449 aa)
DvirGJ15559Uncharacterized protein. (1288 aa)
DvirGJ16013Translation factor waclaw, mitochondrial; Promotes mitochondrial protein synthesis. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Binds to mitochondrial ribosomes in a GTP-dependent manner. (662 aa)
DvirGJ16012Uncharacterized protein, isoform A; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family. (379 aa)
DvirGJ18257RNA-splicing ligase RtcB homolog; Catalytic subunit of the tRNA-splicing ligase complex that acts by directly joining spliced tRNA halves to mature-sized tRNAs by incorporating the precursor-derived splice junction phosphate into the mature tRNA as a canonical 3',5'-phosphodiester. May act as an RNA ligase with broad substrate specificity, and may function toward other RNAs; Belongs to the RtcB family. (506 aa)
DvirGJ17988Tubulin gamma chain; Tubulin is the major constituent of microtubules. The gamma chain is found at microtubule organizing centers (MTOC) such as the spindle poles or the centrosome. (455 aa)
DvirGJ18016Uncharacterized protein. (454 aa)
DvirGJ16931GTP-binding nuclear protein; GTP-binding protein involved in nucleocytoplasmic transport. Required for the import of protein into the nucleus and also for RNA export. Involved in chromatin condensation and control of cell cycle. Belongs to the small GTPase superfamily. Ran family. (216 aa)
DvirGJ16566Uncharacterized protein. (282 aa)
DvirGJ10465Uncharacterized protein. (195 aa)
DvirGJ11110Uncharacterized protein. (305 aa)
DvirGJ10964Hflx-type G domain-containing protein. (525 aa)
DvirGJ10958GTP-binding nuclear protein; GTP-binding protein involved in nucleocytoplasmic transport. Required for the import of protein into the nucleus and also for RNA export. Involved in chromatin condensation and control of cell cycle. Belongs to the small GTPase superfamily. Ran family. (216 aa)
mRRF2Ribosome-releasing factor 2, mitochondrial; Mitochondrial GTPase that mediates the disassembly of ribosomes from messenger RNA at the termination of mitochondrial protein biosynthesis. Not involved in the GTP-dependent ribosomal translocation step during translation elongation; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily. (712 aa)
DvirGJ18919Uncharacterized protein. (229 aa)
DvirGJ19155Tubulin beta chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (461 aa)
DvirGJ19096Polynucleotide 5'-triphosphatase; Bifunctional mRNA-capping enzyme exhibiting RNA 5'- triphosphatase activity in the N-terminal part and mRNA guanylyltransferase activity in the C-terminal part. Catalyzes the first two steps of cap formation: by removing the gamma-phosphate from the 5'-triphosphate end of nascent mRNA to yield a diphosphate end, and by transferring the gmp moiety of GTP to the 5'-diphosphate terminus. (637 aa)
DvirGJ18652Uncharacterized protein. (309 aa)
DvirGJ18826Uncharacterized protein, isoform B. (201 aa)
DvirGJ24163Uncharacterized protein; Belongs to the small GTPase superfamily. Arf family. (186 aa)
DvirGJ23103Elongation factor 1-alpha; This protein promotes the GTP-dependent binding of aminoacyl- tRNA to the A-site of ribosomes during protein biosynthesis. (462 aa)
DvirGJ17947Tubulin gamma chain; Tubulin is the major constituent of microtubules. The gamma chain is found at microtubule organizing centers (MTOC) such as the spindle poles or the centrosome. (486 aa)
DvirGJ24092Uncharacterized protein; Belongs to the small GTPase superfamily. Arf family. (220 aa)
DvirGJ22573Mitochondrial Rho GTPase; Mitochondrial GTPase involved in mitochondrial trafficking. Belongs to the mitochondrial Rho GTPase family. (663 aa)
DvirGJ23156Uncharacterized protein, isoform A; Belongs to the small GTPase superfamily. SAR1 family. (193 aa)
DvirGJ24575GPN-loop GTPase 3; Small GTPase required for proper nuclear import of RNA polymerase II and III (RNAPII and RNAPIII). May act at an RNAP assembly step prior to nuclear import; Belongs to the GPN-loop GTPase family. (287 aa)
DvirGJ24568Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (450 aa)
DvirGJ24556Uncharacterized protein. (182 aa)
DvirGJ23270Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (450 aa)
DvirGJ22744Uncharacterized protein. (231 aa)
DvirGJ24514Uncharacterized protein; Belongs to the small GTPase superfamily. Arf family. (184 aa)
DvirGJ23879GTP:AMP phosphotransferase, mitochondrial; Involved in maintaining the homeostasis of cellular nucleotides by catalyzing the interconversion of nucleoside phosphates. Has GTP:AMP phosphotransferase and ITP:AMP phosphotransferase activities. (217 aa)
DvirGJ23847Uncharacterized protein. (185 aa)
Ras85DRas-like protein 1; Ras proteins bind GDP/GTP and possess intrinsic GTPase activity. Plays a role in eye development by regulating cell growth, survival of postmitotic ommatidial cells and differentiation of photoreceptor cells. During larval development, mediates Ptth/tor signaling leading to the production of ecdysone, a hormone required for the initiation of metamorphosis. (189 aa)
DvirGJ23413TrmE-type G domain-containing protein; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family. (494 aa)
DvirGJ24357Mitochondrial GTPase 1; Plays a role in the regulation of the mitochondrial ribosome assembly and of translational activity. Displays mitochondrial GTPase activity; Belongs to the TRAFAC class YlqF/YawG GTPase family. MTG1 subfamily. (324 aa)
DvirGJ24294Septin-type G domain-containing protein; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family. (419 aa)
GJ24271Adenylosuccinate synthetase; Plays an important role in the de novo pathway and in the salvage pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP (By similarity). Belongs to the adenylosuccinate synthetase family. (448 aa)
DvirGJ23644Uncharacterized protein, isoform A. (546 aa)
DvirGJ23573Tubulin beta chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (446 aa)
DvirGJ17776Uncharacterized protein. (196 aa)
mEFG1Elongation factor G, mitochondrial; Mitochondrial GTPase that catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome. Essential during development as it acts as a retrograde signal from mitochondria to the nuc [...] (747 aa)
DvirGJ17614Uncharacterized protein, isoform A. (330 aa)
DvirGJ16007tRNA(His) guanylyltransferase; Adds a GMP to the 5'-end of tRNA(His) after transcription and RNase P cleavage. (305 aa)
DvirGJ20899Nucleolar GTP-binding protein 2; GTPase that associates with pre-60S ribosomal subunits in the nucleolus and is required for their nuclear export and maturation. Belongs to the TRAFAC class YlqF/YawG GTPase family. NOG2 subfamily. (682 aa)
DvirGJ20446Uncharacterized protein. (182 aa)
DvirGJ21886Uncharacterized protein, isoform A. (382 aa)
DvirGJ20466Tubulin beta chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (447 aa)
DvirGJ20468Uncharacterized protein; Belongs to the small GTPase superfamily. Arf family. (203 aa)
DvirGJ22341Uncharacterized protein. (521 aa)
DvirGJ22328Uncharacterized protein, isoform A. (353 aa)
DvirGJ22327Uncharacterized protein, isoform A. (353 aa)
DvirGJ20064Uncharacterized protein. (198 aa)
DvirGJ21698Septin-type G domain-containing protein; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family. (538 aa)
DvirGJ20079Uncharacterized protein. (270 aa)
DvirGJ21592Tubulin beta chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (454 aa)
DvirGJ12031Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (460 aa)
DvirGJ13838GPN-loop GTPase 2; Small GTPase required for proper localization of RNA polymerase II and III (RNAPII and RNAPIII). May act at an RNAP assembly step prior to nuclear import; Belongs to the GPN-loop GTPase family. (307 aa)
DvirGJ13209Uncharacterized protein. (192 aa)
DvirGJ12166Uncharacterized protein. (397 aa)
DvirGJ13160Signal recognition particle 54 kDa protein; Binds to the signal sequence of presecretory protein when they emerge from the ribosomes and transfers them to TRAM (translocating chain-associating membrane protein). Belongs to the GTP-binding SRP family. SRP54 subfamily. (508 aa)
DvirGJ12241Uncharacterized protein, isoform A. (430 aa)
DvirGJ12256Uncharacterized protein. (355 aa)
DvirGJ13575Uncharacterized protein; Belongs to the small GTPase superfamily. Arf family. (180 aa)
DvirGJ12360Uncharacterized protein. (192 aa)
DvirGJ13559Uncharacterized protein, isoform A; Belongs to the small GTPase superfamily. Arf family. (182 aa)
DvirGJ12943Uncharacterized protein. (184 aa)
DvirGJ12878Uncharacterized protein; Belongs to the small GTPase superfamily. Arf family. (179 aa)
Your Current Organism:
Drosophila virilis
NCBI taxonomy Id: 7244
Other names: D. virilis
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