STRINGSTRING
DvirGJ21945 DvirGJ21945 DvirGJ20161 DvirGJ20161 bi bi DvirGJ10569 DvirGJ10569 DvirGJ24712 DvirGJ24712 DvirGJ24191 DvirGJ24191 DvirGJ12482 DvirGJ12482 DvirGJ13914 DvirGJ13914 DvirGJ19553 DvirGJ19553 DvirGJ13880 DvirGJ13880 DvirGJ11427 DvirGJ11427 DvirGJ12583 DvirGJ12583 DvirGJ14003 DvirGJ14003 DvirGJ12845 DvirGJ12845 DvirGJ12889 DvirGJ12889 DvirGJ13482 DvirGJ13482 DvirGJ11245 DvirGJ11245 DvirGJ12916 DvirGJ12916 DvirGJ14097 DvirGJ14097 DvirGJ11229 DvirGJ11229 Sgf11 Sgf11 DvirGJ11798 DvirGJ11798 DvirGJ11697 DvirGJ11697 DvirGJ11695 DvirGJ11695 DvirGJ13700 DvirGJ13700 mael mael DvirGJ13182 DvirGJ13182 DvirGJ12176 DvirGJ12176 DvirGJ13743 DvirGJ13743 DvirGJ11572 DvirGJ11572 kni kni DvirGJ13774 DvirGJ13774 DvirGJ13789 DvirGJ13789 DvirGJ13265 DvirGJ13265 DvirGJ13266 DvirGJ13266 DvirGJ11446 DvirGJ11446 DvirGJ12760 DvirGJ12760 DvirGJ13943 DvirGJ13943 DvirGJ11363 DvirGJ11363 DvirGJ20887 DvirGJ20887 DvirGJ21457 DvirGJ21457 DvirGJ20236 DvirGJ20236 DvirGJ21595 DvirGJ21595 DvirGJ20165 DvirGJ20165 DvirGJ20128 DvirGJ20128 DvirGJ20653 DvirGJ20653 DvirGJ19993 DvirGJ19993 DvirGJ21774 DvirGJ21774 Eaf Eaf DvirGJ20546 DvirGJ20546 DvirGJ21803 DvirGJ21803 DvirGJ19861 DvirGJ19861 DvirGJ21022 DvirGJ21022 DvirGJ21339 DvirGJ21339 DvirGJ20989 DvirGJ20989 DvirGJ20360 DvirGJ20360 DvirGJ21993 DvirGJ21993 DvirGJ15408 DvirGJ15408 DvirGJ16129 DvirGJ16129 DvirGJ20018 DvirGJ20018 DvirGJ17780 DvirGJ17780 DvirGJ19568 DvirGJ19568 DvirGJ19565 DvirGJ19565 DvirGJ23973 DvirGJ23973 DvirGJ23440 DvirGJ23440 DvirGJ14461 DvirGJ14461 lilli lilli DvirGJ17428 DvirGJ17428 DvirGJ14644 DvirGJ14644 Art4 Art4 DvirGJ23591 DvirGJ23591 DvirGJ23560 DvirGJ23560 DvirGJ23553 DvirGJ23553 DvirGJ23490 DvirGJ23490 DvirGJ24344 DvirGJ24344 DvirGJ23830 DvirGJ23830 DvirGJ22794 DvirGJ22794 DvirGJ22751 DvirGJ22751 DvirGJ23902 DvirGJ23902 DvirGJ23903 DvirGJ23903 DvirGJ23323 DvirGJ23323 DvirGJ23906 DvirGJ23906 DvirGJ23319 DvirGJ23319 DvirGJ23909 DvirGJ23909 DvirGJ23910 DvirGJ23910 DvirGJ23312 DvirGJ23312 DvirGJ24525 DvirGJ24525 DvirGJ23948 DvirGJ23948 DvirGJ23949 DvirGJ23949 DvirGJ23280 DvirGJ23280 DvirGJ24563 DvirGJ24563 DvirGJ22699 DvirGJ22699 e(y)2 e(y)2 DvirGJ23985 DvirGJ23985 DvirGJ22654 DvirGJ22654 DvirGJ24604 DvirGJ24604 DvirGJ23231 DvirGJ23231 trx trx DvirGJ24638 DvirGJ24638 DvirGJ23189 DvirGJ23189 DvirGJ24700 DvirGJ24700 DvirGJ23092 DvirGJ23092 DvirGJ23060 DvirGJ23060 DvirGJ18844 DvirGJ18844 DvirGJ18762 DvirGJ18762 Met Met DvirGJ18625 DvirGJ18625 DvirGJ19539 DvirGJ19539 DvirGJ19114 DvirGJ19114 DvirGJ19212 DvirGJ19212 DvirGJ10876 DvirGJ10876 DvirGJ10888 DvirGJ10888 DvirGJ11090 DvirGJ11090 kay kay Kibra Kibra DvirGJ10785 DvirGJ10785 sim sim e(y)2-2 e(y)2-2 DvirGJ16814 DvirGJ16814 DvirGJ16946 DvirGJ16946 ATbp ATbp GJ17031 GJ17031 DvirGJ16392 DvirGJ16392 DvirGJ16389 DvirGJ16389 DvirGJ18132 DvirGJ18132 GJ17921 GJ17921 DvirGJ18326 DvirGJ18326 DvirGJ17882 DvirGJ17882 DvirGJ15683 DvirGJ15683 DvirGJ15893 DvirGJ15893 DvirGJ15579 DvirGJ15579 foxo foxo DvirGJ16180 DvirGJ16180 DvirGJ16286 DvirGJ16286 DvirGJ18164 DvirGJ18164 DvirGJ17266 DvirGJ17266 DvirGJ21334 DvirGJ21334 DvirGJ13300 DvirGJ13300 DvirGJ13730 DvirGJ13730 DvirGJ19930 DvirGJ19930 ey ey DvirGJ14974 DvirGJ14974 Rpd3 Rpd3 e(y)2-3 e(y)2-3 DvirGJ22512 DvirGJ22512 DVIR88_6g0076 DVIR88_6g0076 DVIR88_6g0011 DVIR88_6g0011 DVIR88_6g0065 DVIR88_6g0065 DVIR88_6g0032 DVIR88_6g0032 tll tll HP1A HP1A h h gl gl ix ix
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
DvirGJ21945Uncharacterized protein, isoform B. (570 aa)
DvirGJ20161Uncharacterized protein, isoform C. (515 aa)
biBi, isoform C. (977 aa)
DvirGJ10569Mothers against decapentaplegic homolog. (594 aa)
DvirGJ24712Uncharacterized protein, isoform D. (2600 aa)
DvirGJ24191Signal transducer and activator of transcription. (848 aa)
DvirGJ12482Uncharacterized protein, isoform G. (1041 aa)
DvirGJ13914Uncharacterized protein, isoform B. (1505 aa)
DvirGJ19553Mothers against decapentaplegic homolog. (510 aa)
DvirGJ13880Uncharacterized protein. (876 aa)
DvirGJ11427Uncharacterized protein, isoform B. (992 aa)
DvirGJ12583Mediator of RNA polymerase II transcription subunit 13; Component of the Mediator complex, a coactivator involved in regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (2698 aa)
DvirGJ14003Uncharacterized protein. (406 aa)
DvirGJ12845Transcription initiation factor IIE subunit beta; Recruits TFIIH to the initiation complex and stimulates the RNA polymerase II C-terminal domain kinase and DNA-dependent ATPase activities of TFIIH. Both TFIIH and TFIIE are required for promoter clearance by RNA polymerase. (292 aa)
DvirGJ12889Uncharacterized protein. (503 aa)
DvirGJ13482RuvB-like helicase; Proposed core component of the chromatin remodeling Ino80 complex which is involved in transcriptional regulation, DNA replication and probably DNA repair. (482 aa)
DvirGJ11245Nuclear receptor domain-containing protein. (367 aa)
DvirGJ12916Mediator of RNA polymerase II transcription subunit 14; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (1537 aa)
DvirGJ14097Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (1069 aa)
DvirGJ11229Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (1466 aa)
Sgf11SAGA-associated factor 11 homolog; Component of the transcription regulatory histone acetylation (HAT) complex SAGA, a multiprotein complex that activates transcription by remodeling chromatin and mediating histone acetylation and deubiquitination. Within the SAGA complex, participates in a subcomplex that specifically deubiquitinates histone H2B. The SAGA complex is recruited to specific gene promoters by activators, where it is required for transcription. Required for nuclear receptor-mediated transactivation. Binds independently on SAGA to promoters in an RNA- dependent manner. Bind [...] (189 aa)
DvirGJ11798General transcription factor IIH subunit. (442 aa)
DvirGJ11697Uncharacterized protein. (386 aa)
DvirGJ11695Uncharacterized protein. (420 aa)
DvirGJ13700Uncharacterized protein, isoform A. (683 aa)
maelProtein maelstrom; Involved both in the piRNA and miRNA metabolic processes. As a component of the meiotic nuage, plays a central role during oogenesis by repressing transposable elements and preventing their mobilization, which is essential for the germline integrity. Repression of transposable elements is mediated via the piRNA metabolic process, which mediates the repression of transposable elements during meiosis by forming complexes composed of piRNAs and Piwi proteins and governs the repression of transposons. As a nuclear component, it is required for proper differentiation in t [...] (444 aa)
DvirGJ13182Mediator of RNA polymerase II transcription subunit 4; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (261 aa)
DvirGJ12176Uncharacterized protein. (2378 aa)
DvirGJ13743Uncharacterized protein. (774 aa)
DvirGJ11572Mediator of RNA polymerase II transcription subunit 11; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (214 aa)
kniKnirps. (481 aa)
DvirGJ13774Uncharacterized protein, isoform A. (654 aa)
DvirGJ13789Uncharacterized protein. (635 aa)
DvirGJ13265Uncharacterized protein. (643 aa)
DvirGJ13266Uncharacterized protein, isoform A. (594 aa)
DvirGJ11446General transcription factor IIH subunit 4; Component of the general transcription and DNA repair factor IIH (TFIIH) core complex which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA. Belongs to the TFB2 family. (492 aa)
DvirGJ12760Mediator of RNA polymerase II transcription subunit 10; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (133 aa)
DvirGJ13943Mediator of RNA polymerase II transcription subunit 19; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (338 aa)
DvirGJ11363Transcription elongation factor 1 homolog; Transcription elongation factor implicated in the maintenance of proper chromatin structure in actively transcribed regions. Belongs to the ELOF1 family. (82 aa)
DvirGJ20887Uncharacterized protein, isoform A. (851 aa)
DvirGJ21457Uncharacterized protein. (1779 aa)
DvirGJ20236Uncharacterized protein. (389 aa)
DvirGJ21595MADS-box domain-containing protein. (468 aa)
DvirGJ20165Mediator of RNA polymerase II transcription subunit 9; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (223 aa)
DvirGJ20128CDK-activating kinase assembly factor MAT1; Stabilizes the cyclin H-CDK7 complex to form a functional CDK-activating kinase (CAK) enzymatic complex. (320 aa)
DvirGJ20653Uncharacterized protein. (413 aa)
DvirGJ19993Uncharacterized protein. (985 aa)
DvirGJ21774FACT complex subunit SSRP1; Component of the FACT complex, a general chromatin factor that acts to reorganize nucleosomes. The FACT complex is involved in multiple processes that require DNA as a template such as mRNA elongation, DNA replication and DNA repair. During transcription elongation the FACT complex acts as a histone chaperone that both destabilizes and restores nucleosomal structure. It facilitates the passage of RNA polymerase II and transcription by promoting the dissociation of one histone H2A-H2B dimer from the nucleosome, then subsequently promotes the reestablishment o [...] (729 aa)
EafEll-associated factor Eaf; Promotes transcriptional elongation by Su(Tpl)/ELL. Essential for development (By similarity); Belongs to the EAF family. (494 aa)
DvirGJ20546Transcription factor. (447 aa)
DvirGJ21803Mediator of RNA polymerase II transcription subunit 8; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (256 aa)
DvirGJ19861MADS-box domain-containing protein. (552 aa)
DvirGJ21022Uncharacterized protein. (442 aa)
DvirGJ21339Uncharacterized protein. (464 aa)
DvirGJ20989Mediator of RNA polymerase II transcription subunit 16; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (804 aa)
DvirGJ20360Enhancer of polycomb-like protein. (2134 aa)
DvirGJ21993Repressor of RNA polymerase III transcription MAF1; Element of the TORC1 signaling pathway that acts as a mediator of diverse signals and that represses RNA polymerase III transcription. Inhibits the de novo assembly of TFIIIB onto DNA. Belongs to the MAF1 family. (226 aa)
DvirGJ15408Uncharacterized protein. (726 aa)
DvirGJ16129Uncharacterized protein. (514 aa)
DvirGJ20018Elongator complex protein 3; Catalytic tRNA acetyltransferase subunit of the RNA polymerase II elongator complex, which is a component of the RNA polymerase II (Pol II) holoenzyme and is involved in transcriptional elongation. (556 aa)
DvirGJ17780Mediator of RNA polymerase II transcription subunit 15; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (713 aa)
DvirGJ19568Uncharacterized protein. (605 aa)
DvirGJ19565Uncharacterized protein. (687 aa)
DvirGJ23973Uncharacterized protein. (619 aa)
DvirGJ23440Transcription initiation factor TFIID subunit 10; TFIID is a multimeric protein complex that plays a central role in mediating promoter responses to various activators and repressors; Belongs to the TAF10 family. (158 aa)
DvirGJ14461Uncharacterized protein. (2149 aa)
lilliAF4/FMR2 family member lilli; Has a role in transcriptional regulation. Acts in parallel with the Ras/MAPK and the PI3K/PKB pathways in the control of cell identity and cellular growth. Essential for regulation of the cytoskeleton and cell growth but not for cell proliferation or growth rate. Required specifically for the microtubule-based basal transport of lipid droplets. Plays a partially redundant function downstream of Raf in cell fate specification in the developing eye. Pair-rule protein that regulates embryonic cellularization, gastrulation and segmentation (By similarity); Bel [...] (1823 aa)
DvirGJ17428Uncharacterized protein. (865 aa)
DvirGJ14644Eyes absent homolog; Belongs to the HAD-like hydrolase superfamily. EYA family. (785 aa)
Art4Histone-arginine methyltransferase CARMER; Methylates (mono- and asymmetric dimethylation) the guanidino nitrogens of arginyl residues in proteins. May methylate histone H3 at 'Arg-17' and activate transcription via chromatin remodeling (By similarity). (538 aa)
DvirGJ23591Mediator of RNA polymerase II transcription subunit 21; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (142 aa)
DvirGJ23560Uncharacterized protein, isoform A. (666 aa)
DvirGJ23553RuvB-like helicase; Proposed core component of the chromatin remodeling Ino80 complex which is involved in transcriptional regulation, DNA replication and probably DNA repair. (456 aa)
DvirGJ23490Uncharacterized protein. (934 aa)
DvirGJ24344Uncharacterized protein. (772 aa)
DvirGJ23830Histone deacetylase complex subunit SAP18; Involved in the tethering of the SIN3 complex to core histone proteins. (149 aa)
DvirGJ22794ARID domain-containing protein. (278 aa)
DvirGJ22751Paired domain-containing protein. (339 aa)
DvirGJ23902Uncharacterized protein. (188 aa)
DvirGJ23903Uncharacterized protein. (217 aa)
DvirGJ23323Uncharacterized protein. (209 aa)
DvirGJ23906Uncharacterized protein. (220 aa)
DvirGJ23319Uncharacterized protein. (184 aa)
DvirGJ23909Uncharacterized protein. (197 aa)
DvirGJ23910Uncharacterized protein. (182 aa)
DvirGJ23312Uncharacterized protein. (899 aa)
DvirGJ24525Mediator of RNA polymerase II transcription subunit 6; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (258 aa)
DvirGJ23948Uncharacterized protein, isoform A. (826 aa)
DvirGJ23949Mediator of RNA polymerase II transcription subunit 31; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (248 aa)
DvirGJ23280Mediator of RNA polymerase II transcription subunit 17; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (646 aa)
DvirGJ24563Histone deacetylase; Belongs to the histone deacetylase family. HD Type 1 subfamily. (436 aa)
DvirGJ22699Uncharacterized protein. (370 aa)
e(y)2Enhancer of yellow 2 transcription factor; Involved in mRNA export coupled transcription activation by association with both the AMEX and the SAGA complexes. The SAGA complex is a multiprotein complex that activates transcription by remodeling chromatin and mediating histone acetylation and deubiquitination. Within the SAGA complex, participates to a subcomplex that specifically deubiquitinates histone H2B. The SAGA complex is recruited to specific gene promoters by activators, where it is required for transcription. Required for nuclear receptor-mediated transactivation. Involved in t [...] (105 aa)
DvirGJ23985Mediator of RNA polymerase II transcription subunit 7; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. (220 aa)
DvirGJ22654Nuclear receptor domain-containing protein. (280 aa)
DvirGJ24604Transcription initiation factor IIF subunit alpha; TFIIF is a general transcription initiation factor that binds to RNA polymerase II and helps to recruit it to the initiation complex in collaboration with TFIIB. It promotes transcription elongation. Belongs to the TFIIF alpha subunit family. (569 aa)
DvirGJ23231General transcription factor IIF subunit 2; TFIIF is a general transcription initiation factor that binds to RNA polymerase II and helps to recruit it to the initiation complex in collaboration with TFIIB. It promotes transcription elongation. This subunit shows ATP-dependent DNA-helicase activity. (286 aa)
trxHistone-lysine N-methyltransferase trithorax; Histone methyltransferase. Methylates 'Lys-4' of histone H3. H3 'Lys-4' methylation represents a specific tag for epigenetic transcriptional activation. Functions in segment determination through interaction with genes of bithorax (BX-C) and antennapedia (ANT-C) complexes. Acts as an activator of BX-C. Involved in the very early regulation of homeotic genes expressed only in the posterior region of the embryo. (3801 aa)
DvirGJ24638Transcription initiation factor IIA subunit 2; TFIIA is a component of the transcription machinery of RNA polymerase II and plays an important role in transcriptional activation; Belongs to the TFIIA subunit 2 family. (129 aa)
DvirGJ23189Uncharacterized protein, isoform B. (1407 aa)
DvirGJ24700Transcriptional adapter. (527 aa)
DvirGJ23092Mothers against decapentaplegic homolog. (769 aa)
DvirGJ23060Transcriptional adapter. (579 aa)
DvirGJ18844Mediator of RNA polymerase II transcription subunit 20; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (246 aa)
DvirGJ18762Mothers against decapentaplegic homolog. (489 aa)
MetMethoprene-tolerant, isoform A. (843 aa)
DvirGJ18625Uncharacterized protein. (627 aa)
DvirGJ19539Uncharacterized protein, isoform A. (441 aa)
DvirGJ19114ARID domain-containing protein. (2417 aa)
DvirGJ19212Homeobox protein cut-like. (2376 aa)
DvirGJ10876Uncharacterized protein. (649 aa)
DvirGJ10888Elongator complex protein 1; Component of the RNA polymerase II elongator complex, a multiprotein complex associated with the RNA polymerase II (Pol II) holoenzyme, and which is involved in transcriptional elongation. Belongs to the ELP1/IKA1 family. (1241 aa)
DvirGJ11090Uncharacterized protein. (549 aa)
kayTranscription factor kayak; Developmentally regulated transcription factor AP-1 binds and recognizes the enhancer DNA sequence: 5'-TGA[CG]TCA-3'. May play a role in the function or determination of a particular subset of cells in the developing embryo. It is able to carry out its function either independently of or in conjunction with Jra (By similarity). (792 aa)
KibraProtein kibra; Regulator of the Hippo/SWH (Sav/Wts/Hpo) signaling pathway, a signaling pathway that plays a pivotal role in organ size control and tumor suppression by restricting proliferation and promoting apoptosis. The core of this pathway is composed of a kinase cascade wherein Hippo (Hpo), in complex with its regulatory protein Salvador (Sav), phosphorylates and activates Warts (Wts) in complex with its regulatory protein Mats, which in turn phosphorylates and inactivates the Yorkie (Yki) oncoprotein. Kibra acts synergistically along with Ex and Mer to regulate the Hippo signalin [...] (1276 aa)
DvirGJ10785Uncharacterized protein. (1622 aa)
simSingle-minded. (699 aa)
e(y)2-2Enhancer of yellow 2 transcription factor; Involved in mRNA export coupled transcription activation by association with both the AMEX and the SAGA complexes. The SAGA complex is a multiprotein complex that activates transcription by remodeling chromatin and mediating histone acetylation and deubiquitination. Within the SAGA complex, participates in a subcomplex that specifically deubiquitinates histone H2B. The SAGA complex is recruited to specific gene promoters by activators, where it is required for transcription. Required for nuclear receptor-mediated transactivation. Involved in t [...] (95 aa)
DvirGJ16814Histone deacetylase; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. (1232 aa)
DvirGJ16946Uncharacterized protein. (984 aa)
ATbpAT-rich binding protein; May be a transcription factor for genes having (A+T) stretches in their promoter and/or enhancer regions. Binds to AT rich DNA (By similarity). (376 aa)
GJ17031Bifunctional lysine-specific demethylase and histidyl-hydroxylase NO66; Oxygenase that can act as both a histone lysine demethylase and a ribosomal histidine hydroxylase. Specifically demethylates 'Lys- 4' (H3K4me) and 'Lys-36' (H3K36me) of histone H3, thereby playing a central role in histone code (By similarity); Belongs to the ROX family. NO66 subfamily. (907 aa)
DvirGJ16392Mediator of RNA polymerase II transcription subunit 18; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (216 aa)
DvirGJ16389Uncharacterized protein. (499 aa)
DvirGJ18132BZIP domain-containing protein. (555 aa)
GJ17921Zinc finger CCCH-type with G patch domain-containing protein; Transcription repressor. (508 aa)
DvirGJ18326Uncharacterized protein, isoform A. (851 aa)
DvirGJ17882Uncharacterized protein. (660 aa)
DvirGJ15683Actin-related protein 8; Plays an important role in the functional organization of mitotic chromosomes. Exhibits low basal ATPase activity, and unable to polymerize; Belongs to the actin family. ARP8 subfamily. (610 aa)
DvirGJ15893Protein HIRA; Required for replication-independent chromatin assembly and for the periodic repression of histone gene transcription during the cell cycle; Belongs to the WD repeat HIR1 family. (991 aa)
DvirGJ15579Transcription elongation factor spt6; Transcription elongation factor that enhances transcription elongation by RNA polymerase II (RNAPII). Belongs to the SPT6 family. (1871 aa)
foxoForkhead box protein O; Transcription factor involved in the regulation of the insulin signaling pathway. Consistently activates both the downstream target Thord4EBP and the feedback control target InR. Involved in negative regulation of the cell cycle, modulating cell growth and proliferation. In response to cellular stresses, such as nutrient deprivation or increased levels of reactive oxygen species, foxo is activated and inhibits growth through the action of target genes such as Thor. Foxo activated in the adult fat body can regulate lifespan in adults; an insulin peptide itself m [...] (609 aa)
DvirGJ16180Transcription initiation factor TFIID subunit 10; TFIID is a multimeric protein complex that plays a central role in mediating promoter responses to various activators and repressors; Belongs to the TAF10 family. (165 aa)
DvirGJ16286E2F_TDP domain-containing protein. (369 aa)
DvirGJ18164Paired domain-containing protein. (440 aa)
DvirGJ17266bZIP_Maf domain-containing protein. (132 aa)
DvirGJ21334Uncharacterized protein, isoform B. (798 aa)
DvirGJ13300Uncharacterized protein, isoform A. (549 aa)
DvirGJ13730Uncharacterized protein, isoform A. (863 aa)
DvirGJ19930One cut domain family member. (1074 aa)
eyEyeless, isoform A. (906 aa)
DvirGJ14974Uncharacterized protein. (577 aa)
Rpd3Histone deacetylase; Belongs to the histone deacetylase family. HD Type 1 subfamily. (527 aa)
e(y)2-3Enhancer of yellow 2 transcription factor; Involved in mRNA export coupled transcription activation by association with both the AMEX and the SAGA complexes. The SAGA complex is a multiprotein complex that activates transcription by remodeling chromatin and mediating histone acetylation and deubiquitination. Within the SAGA complex, participates to a subcomplex that specifically deubiquitinates histone H2B. The SAGA complex is recruited to specific gene promoters by activators, where it is required for transcription. Required for nuclear receptor-mediated transactivation. Involved in t [...] (102 aa)
DvirGJ22512Transcription elongation factor 1 homolog; Transcription elongation factor implicated in the maintenance of proper chromatin structure in actively transcribed regions. Belongs to the ELOF1 family. (82 aa)
DVIR88_6g0076CTF/NF-I domain-containing protein. (798 aa)
DVIR88_6g0011Paired domain-containing protein. (832 aa)
DVIR88_6g0065One cut domain family member. (1076 aa)
DVIR88_6g0032Uncharacterized protein. (909 aa)
tllProtein tailless; Orphan receptor that binds DNA as a monomer to hormone response elements (HRE) containing an extended core motif half-site sequence 5'-AAGTCA-3' in which the 5' flanking nucleotides participate in determining receptor specificity. This receptor binds to the consensus sequence [AG][AG]AAGTCAA. Plays a key role in the establishment of non-metameric domains at the anterior and posterior poles of the embryo. It may also play a role in the nervous system. The maternal terminal pathway activates the tll gene in the termini; TLL activity then represses segmentation and activ [...] (450 aa)
HP1AHeterochromatin protein 1; Structural component of heterochromatin, involved in gene repression and the modification of position-effect-variegation. Recognizes and binds histone H3 tails methylated at 'Lys-9', leading to epigenetic repression (By similarity). (213 aa)
hProtein hairy; Pair-rule protein that regulates embryonic segmentation and adult bristle patterning. Transcriptional repressor of genes that require a bHLH protein for their transcription (e.g. ftz). (379 aa)
glProtein glass; Transcription factor required for gene expression specific to photoreceptor cells. (598 aa)
ixMediator of RNA polymerase II transcription subunit 29; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors (By similarity). (205 aa)
Your Current Organism:
Drosophila virilis
NCBI taxonomy Id: 7244
Other names: D. virilis
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