57 items (Drosophila virilis) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	DvirGJ18195	Uncharacterized protein. (210 aa)
	DvirGJ25754	Plus3 domain-containing protein. (576 aa)
	DvirGJ26626	Uncharacterized protein. (898 aa)
	DvirGJ11246	CYCLIN domain-containing protein; Belongs to the cyclin family. (325 aa)
	DvirGJ14092	DNA-directed RNA polymerases I, II, and III subunit RPABC3; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Common component of RNA polymerases I, II and III which synthesize ribosomal RNA precursors, mRNA precursors and many functional non- coding RNAs, and small RNAs, such as 5S rRNA and tRNAs, respectively. (149 aa)
	DvirGJ12941	Uncharacterized protein, isoform A. (1121 aa)
	DvirGJ11798	General transcription factor IIH subunit. (442 aa)
	Nelf-E	Nelf-E. (281 aa)
	DvirGJ13670	Uncharacterized protein. (809 aa)
	DvirGJ13100	Uncharacterized protein; Belongs to the cyclin family. (1142 aa)
	DvirGJ12147	TPR_REGION domain-containing protein. (1187 aa)
	DvirGJ11446	General transcription factor IIH subunit 4; Component of the general transcription and DNA repair factor IIH (TFIIH) core complex which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA. Belongs to the TFB2 family. (492 aa)
	DvirGJ22116	BRCT domain-containing protein. (703 aa)
	DvirGJ20128	CDK-activating kinase assembly factor MAT1; Stabilizes the cyclin H-CDK7 complex to form a functional CDK-activating kinase (CAK) enzymatic complex. (320 aa)
	DvirGJ20617	Uncharacterized protein. (57 aa)
	DvirGJ22329	Transcription elongation factor SPT4; Component of the DRB sensitivity-inducing factor complex (DSIF complex), which regulates transcription elongation by RNA polymerase II; Belongs to the SPT4 family. (116 aa)
	DvirGJ21774	FACT complex subunit SSRP1; Component of the FACT complex, a general chromatin factor that acts to reorganize nucleosomes. The FACT complex is involved in multiple processes that require DNA as a template such as mRNA elongation, DNA replication and DNA repair. During transcription elongation the FACT complex acts as a histone chaperone that both destabilizes and restores nucleosomal structure. It facilitates the passage of RNA polymerase II and transcription by promoting the dissociation of one histone H2A-H2B dimer from the nucleosome, then subsequently promotes the reestablishment o [...] (729 aa)
	Eaf	Ell-associated factor Eaf; Promotes transcriptional elongation by Su(Tpl)/ELL. Essential for development (By similarity); Belongs to the EAF family. (494 aa)
	DvirGJ21256	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (403 aa)
	DvirGJ20544	Helicase ATP-binding domain-containing protein. (769 aa)
	DvirGJ22408	Uncharacterized protein, isoform A. (778 aa)
	DvirGJ20467	Skp1_POZ domain-containing protein; Belongs to the SKP1 family. (117 aa)
	DvirGJ20465	Transcription elongation factor SPT5. (1085 aa)
	DvirGJ21372	TPR_REGION domain-containing protein. (1274 aa)
	DvirGJ21374	Uncharacterized protein, isoform A. (247 aa)
	DvirGJ18524	Plus3 domain-containing protein. (311 aa)
	DvirGJ22005	Uncharacterized protein, isoform A. (581 aa)
	DvirGJ16048	WD_REPEATS_REGION domain-containing protein. (332 aa)
	DvirGJ15154	Uncharacterized protein; Belongs to the cyclin family. (425 aa)
	TfIIS	TfIIS. (324 aa)
	DvirGJ17109	Uncharacterized protein. (73 aa)
	DvirGJ17829	Uncharacterized protein, isoform A. (615 aa)
	lilli	AF4/FMR2 family member lilli; Has a role in transcriptional regulation. Acts in parallel with the Ras/MAPK and the PI3K/PKB pathways in the control of cell identity and cellular growth. Essential for regulation of the cytoskeleton and cell growth but not for cell proliferation or growth rate. Required specifically for the microtubule-based basal transport of lipid droplets. Plays a partially redundant function downstream of Raf in cell fate specification in the developing eye. Pair-rule protein that regulates embryonic cellularization, gastrulation and segmentation (By similarity); Bel [...] (1823 aa)
	DvirGJ23650	Uncharacterized protein. (67 aa)
	DvirGJ24297	Ubiquitin-like domain-containing protein. (118 aa)
	DvirGJ24371	TFIIS N-terminal domain-containing protein. (677 aa)
	DvirGJ23439	Uncharacterized protein. (480 aa)
	DvirGJ23373	Uncharacterized protein. (173 aa)
	DvirGJ24604	Transcription initiation factor IIF subunit alpha; TFIIF is a general transcription initiation factor that binds to RNA polymerase II and helps to recruit it to the initiation complex in collaboration with TFIIB. It promotes transcription elongation. Belongs to the TFIIF alpha subunit family. (569 aa)
	DvirGJ23231	General transcription factor IIF subunit 2; TFIIF is a general transcription initiation factor that binds to RNA polymerase II and helps to recruit it to the initiation complex in collaboration with TFIIB. It promotes transcription elongation. This subunit shows ATP-dependent DNA-helicase activity. (286 aa)
	DvirGJ23215	AHD domain-containing protein. (966 aa)
	RpII140	DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1176 aa)
	DvirGJ24126	Uncharacterized protein. (592 aa)
	DvirGJ19362	Uncharacterized protein. (578 aa)
	DvirGJ10306	Uncharacterized protein. (540 aa)
	DvirGJ11042	Uncharacterized protein. (683 aa)
	DvirGJ11046	Uncharacterized protein. (567 aa)
	DvirGJ11106	Uncharacterized protein. (131 aa)
	DvirGJ10433	WD_REPEATS_REGION domain-containing protein. (331 aa)
	DvirGJ16576	Uncharacterized protein, isoform A; Belongs to the protein kinase superfamily. (352 aa)
	DvirGJ18149	RPOLD domain-containing protein. (275 aa)
	DvirGJ15676	Uncharacterized protein. (570 aa)
	DvirGJ15949	DNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1889 aa)
	DvirGJ15579	Transcription elongation factor spt6; Transcription elongation factor that enhances transcription elongation by RNA polymerase II (RNAPII). Belongs to the SPT6 family. (1871 aa)
	DvirGJ14413	DNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the archaeal rpoM/eukaryotic RPA12/RPB9/RPC11 RNA polymerase family. (129 aa)
	DvirGJ14299	HDAg domain-containing protein. (1323 aa)
	DvirGJ16235	RNA_pol_L_2 domain-containing protein. (117 aa)

Your Current Organism:

Drosophila virilis

NCBI taxonomy Id: 7244
Other names: D. virilis

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
DvirGJ10306	DvirGJ10433	B4M451	B4M690	Uncharacterized protein.	WD_REPEATS_REGION domain-containing protein.	0.956
DvirGJ10306	DvirGJ11042	B4M451	B4M517	Uncharacterized protein.	Uncharacterized protein.	0.976
DvirGJ10306	DvirGJ11046	B4M451	B4M529	Uncharacterized protein.	Uncharacterized protein.	0.999
DvirGJ10306	DvirGJ11106	B4M451	B4M5E9	Uncharacterized protein.	Uncharacterized protein.	0.889
DvirGJ10306	DvirGJ12147	B4M451	B4LG73	Uncharacterized protein.	TPR_REGION domain-containing protein.	0.965
DvirGJ10306	DvirGJ12941	B4M451	B4LDE4	Uncharacterized protein.	Uncharacterized protein, isoform A.	0.996
DvirGJ10306	DvirGJ13100	B4M451	B4LEZ8	Uncharacterized protein.	Uncharacterized protein; Belongs to the cyclin family.	0.621
DvirGJ10306	DvirGJ14092	B4M451	B4LD87	Uncharacterized protein.	DNA-directed RNA polymerases I, II, and III subunit RPABC3; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Common component of RNA polymerases I, II and III which synthesize ribosomal RNA precursors, mRNA precursors and many functional non- coding RNAs, and small RNAs, such as 5S rRNA and tRNAs, respectively.	0.906
DvirGJ10306	DvirGJ14413	B4M451	B4MBD3	Uncharacterized protein.	DNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the archaeal rpoM/eukaryotic RPA12/RPB9/RPC11 RNA polymerase family.	0.886
DvirGJ10306	DvirGJ15154	B4M451	B4LQT2	Uncharacterized protein.	Uncharacterized protein; Belongs to the cyclin family.	0.683
DvirGJ10306	DvirGJ15579	B4M451	B4MAX8	Uncharacterized protein.	Transcription elongation factor spt6; Transcription elongation factor that enhances transcription elongation by RNA polymerase II (RNAPII). Belongs to the SPT6 family.	0.960
DvirGJ10306	DvirGJ15949	B4M451	B4MAN9	Uncharacterized protein.	DNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.	0.982
DvirGJ10306	DvirGJ16048	B4M451	B4MGP9	Uncharacterized protein.	WD_REPEATS_REGION domain-containing protein.	0.956
DvirGJ10306	DvirGJ16235	B4M451	B4MDE7	Uncharacterized protein.	RNA_pol_L_2 domain-containing protein.	0.879
DvirGJ10306	DvirGJ18149	B4M451	B4M8L9	Uncharacterized protein.	RPOLD domain-containing protein.	0.892
DvirGJ10306	DvirGJ18195	B4M451	B4MDT8	Uncharacterized protein.	Uncharacterized protein.	0.914
DvirGJ10306	DvirGJ18524	B4M451	B4MG60	Uncharacterized protein.	Plus3 domain-containing protein.	0.891
DvirGJ10306	DvirGJ20465	B4M451	B4LNW9	Uncharacterized protein.	Transcription elongation factor SPT5.	0.985
DvirGJ10306	DvirGJ20467	B4M451	B4LNW7	Uncharacterized protein.	Skp1_POZ domain-containing protein; Belongs to the SKP1 family.	0.769
DvirGJ10306	DvirGJ20617	B4M451	B4LLL8	Uncharacterized protein.	Uncharacterized protein.	0.856