25 items (Drosophila virilis) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	DvirGJ13106	Uncharacterized protein, isoform A. (611 aa)
	DvirGJ13345	Uncharacterized protein. (418 aa)
	DvirGJ20054	Receptor protein-tyrosine kinase. (1438 aa)
	DvirGJ21083	Uncharacterized protein, isoform B. (1251 aa)
	DvirGJ21841	Uncharacterized protein, isoform A. (156 aa)
	DvirGJ20786	Uncharacterized protein. (721 aa)
	DvirGJ17377	Hepatocyte growth factor-regulated tyrosine kinase substrate; Essential role in endosome membrane invagination and formation of multivesicular bodies, MVBs. Required during gastrulation and appears to regulate early embryonic signaling pathways. Inhibits tyrosine kinase receptor signaling by promoting degradation of the tyrosine-phosphorylated, active receptor, potentially by sorting activated receptors into MVBs. The MVBs are then trafficked to the lysosome where their contents are degraded. (734 aa)
	DvirGJ22725	Uncharacterized protein, isoform A. (1712 aa)
	Ras85D	Ras-like protein 1; Ras proteins bind GDP/GTP and possess intrinsic GTPase activity. Plays a role in eye development by regulating cell growth, survival of postmitotic ommatidial cells and differentiation of photoreceptor cells. During larval development, mediates Ptth/tor signaling leading to the production of ecdysone, a hormone required for the initiation of metamorphosis. (189 aa)
	DvirGJ18826	Uncharacterized protein, isoform B. (201 aa)
	DvirGJ18146	Uncharacterized protein. (1597 aa)
	DvirGJ16000	Uncharacterized protein, isoform A. (457 aa)
	DvirGJ19679	Uncharacterized protein. (211 aa)
	DvirGJ16220	Ubiquitin-like domain-containing protein. (128 aa)
	DvirGJ16068	Uncharacterized protein. (307 aa)
	EndoA	Endophilin-A; Required presynaptically at the neuromuscular junction. Implicated in synaptic vesicle endocytosis. Belongs to the endophilin family. (369 aa)
	DvirGJ20041	Uncharacterized protein, isoform B. (1337 aa)
	DvirGJ15962	Uncharacterized protein, isoform B. (256 aa)
	DvirGJ24244	Uncharacterized protein, isoform B. (983 aa)
	dos	Dos, isoform C. (911 aa)
	DvirGJ13012	Uncharacterized protein, isoform G. (809 aa)
	DvirGJ12484	Tyrosine-protein phosphatase; Belongs to the protein-tyrosine phosphatase family. Non- receptor class subfamily. (973 aa)
	DvirGJ12975	Uncharacterized protein. (893 aa)
	DvirGJ12391	Uncharacterized protein. (1057 aa)
	DvirGJ11602	WD_REPEATS_REGION domain-containing protein. (432 aa)

Your Current Organism:

Drosophila virilis

NCBI taxonomy Id: 7244
Other names: D. virilis

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
DvirGJ12391	DvirGJ13345	B4LDS6	B4LHQ2	Uncharacterized protein.	Uncharacterized protein.	0.520
DvirGJ12391	DvirGJ16000	B4LDS6	B4MAX6	Uncharacterized protein.	Uncharacterized protein, isoform A.	0.471
DvirGJ12391	DvirGJ16068	B4LDS6	B4MGL9	Uncharacterized protein.	Uncharacterized protein.	0.471
DvirGJ12391	DvirGJ16220	B4LDS6	B4MDC8	Uncharacterized protein.	Ubiquitin-like domain-containing protein.	0.507
DvirGJ12391	DvirGJ18146	B4LDS6	B4M8L2	Uncharacterized protein.	Uncharacterized protein.	0.790
DvirGJ12391	DvirGJ19679	B4LDS6	B4MCL9	Uncharacterized protein.	Uncharacterized protein.	0.704
DvirGJ12391	DvirGJ20054	B4LDS6	B4LLF8	Uncharacterized protein.	Receptor protein-tyrosine kinase.	0.788
DvirGJ12391	DvirGJ21841	B4LDS6	B4LR26	Uncharacterized protein.	Uncharacterized protein, isoform A.	0.504
DvirGJ12484	DvirGJ12975	B4LCU6	B4LDS5	Tyrosine-protein phosphatase; Belongs to the protein-tyrosine phosphatase family. Non- receptor class subfamily.	Uncharacterized protein.	0.650
DvirGJ12484	DvirGJ17377	B4LCU6	B4LUT9	Tyrosine-protein phosphatase; Belongs to the protein-tyrosine phosphatase family. Non- receptor class subfamily.	Hepatocyte growth factor-regulated tyrosine kinase substrate; Essential role in endosome membrane invagination and formation of multivesicular bodies, MVBs. Required during gastrulation and appears to regulate early embryonic signaling pathways. Inhibits tyrosine kinase receptor signaling by promoting degradation of the tyrosine-phosphorylated, active receptor, potentially by sorting activated receptors into MVBs. The MVBs are then trafficked to the lysosome where their contents are degraded.	0.636
DvirGJ12484	DvirGJ19679	B4LCU6	B4MCL9	Tyrosine-protein phosphatase; Belongs to the protein-tyrosine phosphatase family. Non- receptor class subfamily.	Uncharacterized protein.	0.695
DvirGJ12484	DvirGJ20054	B4LCU6	B4LLF8	Tyrosine-protein phosphatase; Belongs to the protein-tyrosine phosphatase family. Non- receptor class subfamily.	Receptor protein-tyrosine kinase.	0.667
DvirGJ12484	DvirGJ20786	B4LCU6	B4LS62	Tyrosine-protein phosphatase; Belongs to the protein-tyrosine phosphatase family. Non- receptor class subfamily.	Uncharacterized protein.	0.639
DvirGJ12484	DvirGJ21083	B4LCU6	B4LN51	Tyrosine-protein phosphatase; Belongs to the protein-tyrosine phosphatase family. Non- receptor class subfamily.	Uncharacterized protein, isoform B.	0.637
DvirGJ12484	DvirGJ24244	B4LCU6	A0A0Q9WFV0	Tyrosine-protein phosphatase; Belongs to the protein-tyrosine phosphatase family. Non- receptor class subfamily.	Uncharacterized protein, isoform B.	0.596
DvirGJ12484	EndoA	B4LCU6	Q8I190	Tyrosine-protein phosphatase; Belongs to the protein-tyrosine phosphatase family. Non- receptor class subfamily.	Endophilin-A; Required presynaptically at the neuromuscular junction. Implicated in synaptic vesicle endocytosis. Belongs to the endophilin family.	0.575
DvirGJ12484	dos	B4LCU6	A0A0Q9WHY7	Tyrosine-protein phosphatase; Belongs to the protein-tyrosine phosphatase family. Non- receptor class subfamily.	Dos, isoform C.	0.649
DvirGJ12975	DvirGJ12484	B4LDS5	B4LCU6	Uncharacterized protein.	Tyrosine-protein phosphatase; Belongs to the protein-tyrosine phosphatase family. Non- receptor class subfamily.	0.650
DvirGJ12975	DvirGJ13012	B4LDS5	A0A0Q9WI38	Uncharacterized protein.	Uncharacterized protein, isoform G.	0.925
DvirGJ12975	DvirGJ13106	B4LDS5	B4LF08	Uncharacterized protein.	Uncharacterized protein, isoform A.	0.989