STRINGSTRING
DvirGJ14342 DvirGJ14342 DvirGJ14777 DvirGJ14777 DvirGJ25993 DvirGJ25993 DvirGJ12966 DvirGJ12966 DvirGJ12309 DvirGJ12309 DvirGJ13078 DvirGJ13078 DvirGJ13794 DvirGJ13794 DvirGJ13306 DvirGJ13306 DvirGJ21473 DvirGJ21473 DvirGJ20704 DvirGJ20704 DvirGJ20076 DvirGJ20076 DvirGJ20070 DvirGJ20070 DvirGJ22414 DvirGJ22414 DvirGJ21075 DvirGJ21075 DvirGJ20481 DvirGJ20481 DvirGJ19871 DvirGJ19871 DvirGJ14710 DvirGJ14710 DvirGJ17755 DvirGJ17755 DvirGJ17814 DvirGJ17814 DvirGJ17456 DvirGJ17456 DvirGJ24206 DvirGJ24206 DvirGJ24376 DvirGJ24376 DvirGJ22560 DvirGJ22560 DvirGJ23056 DvirGJ23056 DvirGJ19496 DvirGJ19496 DvirGJ10914 DvirGJ10914 DvirGJ11070 DvirGJ11070 DvirGJ15347 DvirGJ15347 DvirGJ10583 DvirGJ10583 DvirGJ10668 DvirGJ10668 DvirGJ16984 DvirGJ16984 DvirGJ16986 DvirGJ16986 DvirGJ18148 DvirGJ18148 DvirGJ18023 DvirGJ18023 DvirGJ15884 DvirGJ15884
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
DvirGJ14342Uncharacterized protein. (622 aa)
DvirGJ14777DNA helicase; Belongs to the MCM family. (831 aa)
DvirGJ25993Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (314 aa)
DvirGJ12966DNA primase; Belongs to the eukaryotic-type primase small subunit family. (434 aa)
DvirGJ12309Cell division control protein; Involved in the initiation of DNA replication. Also participates in checkpoint controls that ensure DNA replication is completed before mitosis is initiated; Belongs to the CDC6/cdc18 family. (613 aa)
DvirGJ13078DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...] (720 aa)
DvirGJ13794DNA primase large subunit; Regulatory subunit of the DNA primase complex and component of the DNA polymerase alpha complex (also known as the alpha DNA polymerase-primase complex) which play an essential role in the initiation of DNA synthesis. The primase subunit of the polymerase alpha complex initiates DNA synthesis by oligomerising short RNA primers on both leading and lagging strands. (533 aa)
DvirGJ13306DNA polymerase epsilon subunit; Participates in DNA repair and in chromosomal DNA replication; Belongs to the DNA polymerase epsilon subunit B family. (526 aa)
DvirGJ21473ORC_WH_C domain-containing protein. (717 aa)
DvirGJ20704Uncharacterized protein. (188 aa)
DvirGJ20076DNA helicase; Belongs to the MCM family. (864 aa)
DvirGJ20070Origin recognition complex subunit 1; Component of the origin recognition complex (ORC) that binds origins of replication. DNA-binding is ATP-dependent, however specific DNA sequences that define origins of replication have not been identified so far. ORC is required to assemble the pre-replication complex necessary to initiate DNA replication. (923 aa)
DvirGJ22414CBFD_NFYB_HMF domain-containing protein. (162 aa)
DvirGJ21075Origin recognition complex subunit 4; Component of the origin recognition complex (ORC) that binds origins of replication; Belongs to the ORC4 family. (456 aa)
DvirGJ20481Uncharacterized protein. (247 aa)
DvirGJ19871CDT1 domain-containing protein. (721 aa)
DvirGJ14710RPA_C domain-containing protein. (242 aa)
DvirGJ17755Protein kinase domain-containing protein. (643 aa)
DvirGJ17814Mcm10 domain-containing protein. (784 aa)
DvirGJ17456DBF4-type domain-containing protein. (1836 aa)
DvirGJ24206DNA helicase; Belongs to the MCM family. (885 aa)
DvirGJ24376DNA polymerase epsilon catalytic subunit; DNA polymerase II participates in chromosomal DNA replication; Belongs to the DNA polymerase type-B family. (2259 aa)
DvirGJ22560J domain-containing protein. (295 aa)
DvirGJ23056Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage. (609 aa)
DvirGJ19496Uncharacterized protein. (113 aa)
DvirGJ10914MCM domain-containing protein; Belongs to the MCM family. (876 aa)
DvirGJ11070DNA polymerase. (1481 aa)
DvirGJ15347Uncharacterized protein. (577 aa)
DvirGJ10583DNA helicase; Belongs to the MCM family. (734 aa)
DvirGJ10668DNA polymerase alpha subunit B; Accessory subunit of the DNA polymerase alpha complex (also known as the alpha DNA polymerase-primase complex) which plays an essential role in the initiation of DNA synthesis. (600 aa)
DvirGJ16984Protein kinase domain-containing protein. (749 aa)
DvirGJ16986DNA helicase; Belongs to the MCM family. (824 aa)
DvirGJ18148AAA domain-containing protein. (460 aa)
DvirGJ18023CBFD_NFYB_HMF domain-containing protein. (130 aa)
DvirGJ15884Uncharacterized protein. (497 aa)
Your Current Organism:
Drosophila virilis
NCBI taxonomy Id: 7244
Other names: D. virilis
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