STRINGSTRING
DvirGJ25985 DvirGJ25985 DvirGJ10492 DvirGJ10492 DvirGJ25832 DvirGJ25832 DvirGJ14509 DvirGJ14509 DvirGJ14183 DvirGJ14183 DvirGJ15195 DvirGJ15195 DvirGJ16220 DvirGJ16220 DvirGJ16241 DvirGJ16241 DvirGJ18358 DvirGJ18358 DvirGJ17750 DvirGJ17750 DvirGJ18434 DvirGJ18434 DvirGJ14777 DvirGJ14777 DvirGJ15428 DvirGJ15428 Pros28.1 Pros28.1 DvirGJ18483 DvirGJ18483 DvirGJ16065 DvirGJ16065 DvirGJ16068 DvirGJ16068 DvirGJ15529 DvirGJ15529 DvirGJ14342 DvirGJ14342 DvirGJ15572 DvirGJ15572 DvirGJ16000 DvirGJ16000 DvirGJ15627 DvirGJ15627 DvirGJ15904 DvirGJ15904 DvirGJ15827 DvirGJ15827 DvirGJ15825 DvirGJ15825 GJ15767 GJ15767 DvirGJ17903 DvirGJ17903 DvirGJ18148 DvirGJ18148 DvirGJ16628 DvirGJ16628 DvirGJ16670 DvirGJ16670 DvirGJ16380 DvirGJ16380 DvirGJ16986 DvirGJ16986 DvirGJ16979 DvirGJ16979 DvirGJ16557 DvirGJ16557 DvirGJ16567 DvirGJ16567 DvirGJ16572 DvirGJ16572 DvirGJ16817 DvirGJ16817 DvirGJ10583 DvirGJ10583 DvirGJ10047 DvirGJ10047 DvirGJ10914 DvirGJ10914 DvirGJ10880 DvirGJ10880 DvirGJ18891 DvirGJ18891 DvirGJ19003 DvirGJ19003 DvirGJ19383 DvirGJ19383 Pros28.1B Pros28.1B DvirGJ18822 DvirGJ18822 DvirGJ24151 DvirGJ24151 DvirGJ23109 DvirGJ23109 DvirGJ24651 DvirGJ24651 DvirGJ22583 DvirGJ22583 DvirGJ24070 DvirGJ24070 DvirGJ24517 DvirGJ24517 DvirGJ23330 DvirGJ23330 DvirGJ24473 DvirGJ24473 DvirGJ24373 DvirGJ24373 DvirGJ23747 DvirGJ23747 DvirGJ22971 DvirGJ22971 DvirGJ23001 DvirGJ23001 DvirGJ24206 DvirGJ24206 DvirGJ17369 DvirGJ17369 DvirGJ17367 DvirGJ17367 DvirGJ17300 DvirGJ17300 DvirGJ10111 DvirGJ10111 DvirGJ20073 DvirGJ20073 DvirGJ11636 DvirGJ11636 DvirGJ15897 DvirGJ15897 DvirGJ17542 DvirGJ17542 DvirGJ21841 DvirGJ21841 DvirGJ22314 DvirGJ22314 DvirGJ21990 DvirGJ21990 DvirGJ20367 DvirGJ20367 DvirGJ21948 DvirGJ21948 DvirGJ20967 DvirGJ20967 DvirGJ20973 DvirGJ20973 DvirGJ21921 DvirGJ21921 DvirGJ19871 DvirGJ19871 DvirGJ21890 DvirGJ21890 DvirGJ20480 DvirGJ20480 DvirGJ20481 DvirGJ20481 DvirGJ21075 DvirGJ21075 DvirGJ22419 DvirGJ22419 DvirGJ21772 DvirGJ21772 DvirGJ20070 DvirGJ20070 DvirGJ20076 DvirGJ20076 DvirGJ20086 DvirGJ20086 DvirGJ20688 DvirGJ20688 DvirGJ20704 DvirGJ20704 DvirGJ20726 DvirGJ20726 DvirGJ22197 DvirGJ22197 DvirGJ20175 DvirGJ20175 DvirGJ21597 DvirGJ21597 DvirGJ21473 DvirGJ21473 DvirGJ13326 DvirGJ13326 DvirGJ11487 DvirGJ11487 DvirGJ11488 DvirGJ11488 DvirGJ13183 DvirGJ13183 DvirGJ11606 DvirGJ11606 DvirGJ11618 DvirGJ11618 DvirGJ13078 DvirGJ13078 DvirGJ12309 DvirGJ12309 DvirGJ11813 DvirGJ11813 DvirGJ14389 DvirGJ14389 DvirGJ11829 DvirGJ11829 DvirGJ12411 DvirGJ12411 DvirGJ12485 DvirGJ12485 DvirGJ11331 DvirGJ11331 DvirGJ12802 DvirGJ12802 DvirGJ25993 DvirGJ25993 DvirGJ26088 DvirGJ26088
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
DvirGJ25985Proteasome subunit beta; Belongs to the peptidase T1B family. (247 aa)
DvirGJ10492Uncharacterized protein. (813 aa)
DvirGJ25832AAA domain-containing protein; Belongs to the AAA ATPase family. (433 aa)
DvirGJ1450926S proteasome non-ATPase regulatory subunit 1; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair; Belongs to the proteasome subunit S1 family. (1042 aa)
DvirGJ14183F-box domain-containing protein. (584 aa)
DvirGJ15195PI31_Prot_N domain-containing protein. (262 aa)
DvirGJ16220Ubiquitin-like domain-containing protein. (128 aa)
DvirGJ16241RING-type domain-containing protein. (149 aa)
DvirGJ18358Uncharacterized protein, isoform A. (270 aa)
DvirGJ17750Uncharacterized protein, isoform A; Belongs to the cullin family. (773 aa)
DvirGJ18434Proteasome subunit alpha type; The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH; Belongs to the peptidase T1A family. (244 aa)
DvirGJ14777DNA helicase; Belongs to the MCM family. (831 aa)
DvirGJ15428Proteasome subunit alpha type; The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH; Belongs to the peptidase T1A family. (286 aa)
Pros28.1Proteasome subunit alpha type; The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH; Belongs to the peptidase T1A family. (249 aa)
DvirGJ18483Uncharacterized protein; Belongs to the SKP1 family. (150 aa)
DvirGJ16065Uncharacterized protein, isoform A. (746 aa)
DvirGJ16068Uncharacterized protein. (307 aa)
DvirGJ15529Uncharacterized protein. (127 aa)
DvirGJ14342Uncharacterized protein. (622 aa)
DvirGJ15572AAA domain-containing protein; Belongs to the AAA ATPase family. (408 aa)
DvirGJ16000Uncharacterized protein, isoform A. (457 aa)
DvirGJ15627Proteasome subunit alpha type; The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH; Belongs to the peptidase T1A family. (247 aa)
DvirGJ15904Zf-rbx1 domain-containing protein. (104 aa)
DvirGJ15827AAA domain-containing protein; Belongs to the AAA ATPase family. (397 aa)
DvirGJ15825RING-type domain-containing protein. (108 aa)
GJ15767Ubiquitin-conjugating enzyme E2 S; Catalyzes the covalent attachment of ubiquitin to other proteins. Acts as an essential factor of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated ubiquitin ligase that controls progression through mitosis. Acts by specifically elongating polyubiquitin chains initiated by the E2 enzyme vih/UbcH10 on APC/C substrates, enhancing the degradation of APC/C substrates by the proteasome and promoting mitotic exit. (208 aa)
DvirGJ17903Uncharacterized protein, isoform B; Belongs to the cyclin family. (698 aa)
DvirGJ18148AAA domain-containing protein. (460 aa)
DvirGJ16628Proteasome subunit beta. (304 aa)
DvirGJ16670Uncharacterized protein. (501 aa)
DvirGJ16380WD_REPEATS_REGION domain-containing protein. (478 aa)
DvirGJ16986DNA helicase; Belongs to the MCM family. (824 aa)
DvirGJ16979Uncharacterized protein. (607 aa)
DvirGJ16557Proteasome endopeptidase complex; Belongs to the peptidase T1A family. (234 aa)
DvirGJ16567Uncharacterized protein. (328 aa)
DvirGJ16572Uncharacterized protein. (2014 aa)
DvirGJ16817Uncharacterized protein. (248 aa)
DvirGJ10583DNA helicase; Belongs to the MCM family. (734 aa)
DvirGJ10047Proteasome subunit beta; Belongs to the peptidase T1B family. (265 aa)
DvirGJ10914MCM domain-containing protein; Belongs to the MCM family. (876 aa)
DvirGJ10880Proteasome subunit beta. (205 aa)
DvirGJ18891Uncharacterized protein; Belongs to the SKP1 family. (162 aa)
DvirGJ19003Anaphase-promoting complex subunit 4; Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. Belongs to the APC4 family. (798 aa)
DvirGJ19383AAA domain-containing protein; Belongs to the AAA ATPase family. (405 aa)
Pros28.1BProteasome subunit alpha type; The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH; Belongs to the peptidase T1A family. (251 aa)
DvirGJ18822Skp1_POZ domain-containing protein; Belongs to the SKP1 family. (145 aa)
DvirGJ24151AAA domain-containing protein; Belongs to the AAA ATPase family. (399 aa)
DvirGJ23109PDZ domain-containing protein. (219 aa)
DvirGJ24651PCI domain-containing protein. (382 aa)
DvirGJ22583Uncharacterized protein, isoform A; Belongs to the AAA ATPase family. (428 aa)
DvirGJ24070AAA domain-containing protein; Belongs to the AAA ATPase family. (439 aa)
DvirGJ24517AAA domain-containing protein; Belongs to the AAA ATPase family. (400 aa)
DvirGJ23330PCI domain-containing protein. (497 aa)
DvirGJ24473Proteasome subunit alpha type; The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH; Belongs to the peptidase T1A family. (234 aa)
DvirGJ24373TPR_REGION domain-containing protein. (720 aa)
DvirGJ23747Uncharacterized protein. (208 aa)
DvirGJ22971UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family. (147 aa)
DvirGJ23001Uncharacterized protein, isoform B; Belongs to the AAA ATPase family. (404 aa)
DvirGJ24206DNA helicase; Belongs to the MCM family. (885 aa)
DvirGJ17369Proteasome subunit beta. (193 aa)
DvirGJ17367Proteasome subunit beta. (231 aa)
DvirGJ17300Proteasome subunit beta. (206 aa)
DvirGJ10111MPN domain-containing protein. (308 aa)
DvirGJ20073Uncharacterized protein, isoform A. (691 aa)
DvirGJ11636PCI domain-containing protein. (495 aa)
DvirGJ15897Proteasome subunit alpha type; The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH; Belongs to the peptidase T1A family. (273 aa)
DvirGJ17542Uncharacterized protein. (373 aa)
DvirGJ21841Uncharacterized protein, isoform A. (156 aa)
DvirGJ22314Uncharacterized protein, isoform A; Belongs to the SKP1 family. (140 aa)
DvirGJ21990Proteasome subunit alpha type; The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH; Belongs to the peptidase T1A family. (263 aa)
DvirGJ20367Proteasome subunit alpha type; The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH; Belongs to the peptidase T1A family. (245 aa)
DvirGJ21948Anaphase-promoting complex subunit 10; Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin-protein ligase complex that controls progression through mitosis and the G1 phase of the cell cycle. (197 aa)
DvirGJ20967Proteasome subunit beta. (312 aa)
DvirGJ20973Uncharacterized protein, isoform A. (211 aa)
DvirGJ21921Proteasome subunit beta. (279 aa)
DvirGJ19871CDT1 domain-containing protein. (721 aa)
DvirGJ21890Uncharacterized protein, isoform A; Belongs to the cullin family. (789 aa)
DvirGJ20480Proteasome subunit alpha type; The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH; Belongs to the peptidase T1A family. (252 aa)
DvirGJ20481Uncharacterized protein. (247 aa)
DvirGJ21075Origin recognition complex subunit 4; Component of the origin recognition complex (ORC) that binds origins of replication; Belongs to the ORC4 family. (456 aa)
DvirGJ22419RING-type domain-containing protein. (117 aa)
DvirGJ21772PCI domain-containing protein. (441 aa)
DvirGJ20070Origin recognition complex subunit 1; Component of the origin recognition complex (ORC) that binds origins of replication. DNA-binding is ATP-dependent, however specific DNA sequences that define origins of replication have not been identified so far. ORC is required to assemble the pre-replication complex necessary to initiate DNA replication. (923 aa)
DvirGJ20076DNA helicase; Belongs to the MCM family. (864 aa)
DvirGJ20086Proteasome subunit beta. (222 aa)
DvirGJ20688Uncharacterized protein, isoform A; Belongs to the SKP1 family. (162 aa)
DvirGJ20704Uncharacterized protein. (188 aa)
DvirGJ20726Proteasome subunit alpha type; The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH; Belongs to the peptidase T1A family. (252 aa)
DvirGJ22197Uncharacterized protein. (221 aa)
DvirGJ20175Uncharacterized protein. (115 aa)
DvirGJ21597MPN domain-containing protein. (363 aa)
DvirGJ21473ORC_WH_C domain-containing protein. (717 aa)
DvirGJ13326Uncharacterized protein. (328 aa)
DvirGJ11487KxDL domain-containing protein. (231 aa)
DvirGJ11488UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family. (176 aa)
DvirGJ13183Uncharacterized protein. (926 aa)
DvirGJ11606Proteasome subunit beta. (270 aa)
DvirGJ11618PCI domain-containing protein. (264 aa)
DvirGJ13078DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...] (720 aa)
DvirGJ12309Cell division control protein; Involved in the initiation of DNA replication. Also participates in checkpoint controls that ensure DNA replication is completed before mitosis is initiated; Belongs to the CDC6/cdc18 family. (613 aa)
DvirGJ11813Cyclin N-terminal domain-containing protein; Belongs to the cyclin family. (511 aa)
DvirGJ14389PCI domain-containing protein. (389 aa)
DvirGJ11829VWFA domain-containing protein. (391 aa)
DvirGJ12411Uncharacterized protein; Belongs to the SKP1 family. (159 aa)
DvirGJ12485RING-type domain-containing protein. (131 aa)
DvirGJ1133126S proteasome non-ATPase regulatory subunit 2; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair; Belongs to the proteasome subunit S2 family. (915 aa)
DvirGJ12802PCI domain-containing protein. (264 aa)
DvirGJ25993Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (314 aa)
DvirGJ26088RING-type domain-containing protein. (85 aa)
Your Current Organism:
Drosophila virilis
NCBI taxonomy Id: 7244
Other names: D. virilis
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