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DvirGJ19974 DvirGJ19974 DvirGJ11248 DvirGJ11248 DvirGJ11957 DvirGJ11957 DvirGJ22862 DvirGJ22862 DvirGJ23792 DvirGJ23792 DvirGJ10817 DvirGJ10817 DvirGJ17070 DvirGJ17070 DvirGJ12416 DvirGJ12416 DvirGJ12370 DvirGJ12370 DvirGJ11663 DvirGJ11663 DvirGJ12039 DvirGJ12039 DvirGJ11371 DvirGJ11371 DvirGJ22018 DvirGJ22018 DvirGJ22111 DvirGJ22111 DvirGJ21546 DvirGJ21546 DvirGJ20729 DvirGJ20729 DvirGJ15342 DvirGJ15342 DvirGJ15311 DvirGJ15311 DvirGJ15838 DvirGJ15838 DvirGJ16988 DvirGJ16988 DvirGJ16987 DvirGJ16987 DvirGJ10975 DvirGJ10975 DvirGJ19287 DvirGJ19287 DvirGJ22544 DvirGJ22544 DvirGJ24090 DvirGJ24090 DvirGJ24648 DvirGJ24648 DvirGJ23961 DvirGJ23961 DvirGJ23876 DvirGJ23876 DvirGJ23339 DvirGJ23339 DvirGJ23871 DvirGJ23871 DvirGJ23421 DvirGJ23421 DvirGJ23422 DvirGJ23422 DvirGJ17812 DvirGJ17812 DvirGJ20393 DvirGJ20393 DvirGJ20394 DvirGJ20394 DvirGJ21343 DvirGJ21343 DvirGJ19975 DvirGJ19975 DvirGJ22180 DvirGJ22180 DvirGJ11233 DvirGJ11233 DvirGJ11232 DvirGJ11232
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
DvirGJ19974Uncharacterized protein. (610 aa)
DvirGJ11248Isocitrate dehydrogenase [NAD] subunit, mitochondrial. (367 aa)
DvirGJ11957Succinate--CoA ligase [GDP-forming] subunit beta, mitochondrial; GTP-specific succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. (420 aa)
DvirGJ22862Malic enzyme. (630 aa)
DvirGJ23792Succinate--CoA ligase [ADP-forming] subunit beta, mitochondrial; ATP-specific succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of ATP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. (473 aa)
DvirGJ10817Malic enzyme; Belongs to the malic enzymes family. (824 aa)
DvirGJ17070Citrate synthase; Belongs to the citrate synthase family. (508 aa)
DvirGJ12416Succinate--CoA ligase [ADP/GDP-forming] subunit alpha, mitochondrial; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and specificity for either ATP or GTP is provided by different beta subunits. (328 aa)
DvirGJ12370Transket_pyr domain-containing protein. (1235 aa)
DvirGJ11663Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial; Flavoprotein (FP) subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q). (651 aa)
DvirGJ12039Uncharacterized protein, isoform A. (1115 aa)
DvirGJ11371Dihydrolipoyl dehydrogenase. (504 aa)
DvirGJ22018Iso_dh domain-containing protein. (392 aa)
DvirGJ22111Ubiquinone biosynthesis protein; Lipid-binding protein involved in the biosynthesis of coenzyme Q, also named ubiquinone, an essential lipid-soluble electron transporter for aerobic cellular respiration. (343 aa)
DvirGJ21546Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial; Flavoprotein (FP) subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q). (665 aa)
DvirGJ20729Iso_dh domain-containing protein. (383 aa)
DvirGJ15342Succinate--CoA ligase [ADP/GDP-forming] subunit alpha, mitochondrial; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and specificity for either ATP or GTP is provided by different beta subunits. (344 aa)
DvirGJ15311Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial; Iron-sulfur protein (IP) subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q). (382 aa)
DvirGJ15838Isocitrate dehydrogenase [NAD] subunit, mitochondrial. (381 aa)
DvirGJ16988Uncharacterized protein. (500 aa)
DvirGJ16987Uncharacterized protein, isoform A. (496 aa)
DvirGJ10975Uncharacterized protein, isoform C. (393 aa)
DvirGJ19287Malate dehydrogenase. (343 aa)
DvirGJ22544Uncharacterized protein; Belongs to the LDH/MDH superfamily. (336 aa)
DvirGJ24090Uncharacterized protein, isoform A. (371 aa)
DvirGJ24648Succinate dehydrogenase [ubiquinone] cytochrome b small subunit; Membrane-anchoring subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q); Belongs to the CybS family. (184 aa)
DvirGJ23961FAA_hydrolase domain-containing protein. (230 aa)
DvirGJ23876Uncharacterized protein. (269 aa)
DvirGJ23339Aconitate hydratase, mitochondrial; Belongs to the aconitase/IPM isomerase family. (787 aa)
DvirGJ23871Uncharacterized protein. (171 aa)
DvirGJ23421Lipoyl-binding domain-containing protein. (481 aa)
DvirGJ23422Lipoyl-binding domain-containing protein. (474 aa)
DvirGJ17812Aconitate hydratase, mitochondrial; Belongs to the aconitase/IPM isomerase family. (785 aa)
DvirGJ20393Uncharacterized protein; Belongs to the LDH/MDH superfamily. (380 aa)
DvirGJ20394Uncharacterized protein; Belongs to the LDH/MDH superfamily. (346 aa)
DvirGJ21343Uncharacterized protein, isoform B. (613 aa)
DvirGJ19975Uncharacterized protein. (607 aa)
DvirGJ22180Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial; Iron-sulfur protein (IP) subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q). (296 aa)
DvirGJ11233Uncharacterized protein. (476 aa)
DvirGJ11232Uncharacterized protein. (484 aa)
Your Current Organism:
Drosophila virilis
NCBI taxonomy Id: 7244
Other names: D. virilis
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