STRINGSTRING
DvirGJ24563 DvirGJ24563 fru fru dsx dsx DvirGJ16814 DvirGJ16814 elav elav Rpd3 Rpd3 HP1A HP1A
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
DvirGJ24563Histone deacetylase; Belongs to the histone deacetylase family. HD Type 1 subfamily. (436 aa)
fruFru, isoform C. (865 aa)
dsxDsx. (417 aa)
DvirGJ16814Histone deacetylase; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. (1232 aa)
elavEmbryonic lethal, abnormal vision. (482 aa)
Rpd3Histone deacetylase; Belongs to the histone deacetylase family. HD Type 1 subfamily. (527 aa)
HP1AHeterochromatin protein 1; Structural component of heterochromatin, involved in gene repression and the modification of position-effect-variegation. Recognizes and binds histone H3 tails methylated at 'Lys-9', leading to epigenetic repression (By similarity). (213 aa)
Your Current Organism:
Drosophila virilis
NCBI taxonomy Id: 7244
Other names: D. virilis
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