STRINGSTRING
DvirGJ11779 DvirGJ11779 DvirGJ14710 DvirGJ14710 DvirGJ13289 DvirGJ13289 DvirGJ23828 DvirGJ23828 DvirGJ22809 DvirGJ22809 DvirGJ23056 DvirGJ23056 DvirGJ19496 DvirGJ19496 DvirGJ18611 DvirGJ18611 DvirGJ10048 DvirGJ10048 DvirGJ10382 DvirGJ10382 okr okr DvirGJ15664 DvirGJ15664 DvirGJ15211 DvirGJ15211 DvirGJ16256 DvirGJ16256 DvirGJ16059 DvirGJ16059
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
DvirGJ11779DNA polymerase. (1092 aa)
DvirGJ14710RPA_C domain-containing protein. (242 aa)
DvirGJ13289Double-strand break repair protein; Involved in DNA double-strand break repair (DSBR). Possesses single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity. Also involved in meiotic DSB processing. (623 aa)
DvirGJ23828Uncharacterized protein. (146 aa)
DvirGJ22809RECA_2 domain-containing protein. (349 aa)
DvirGJ23056Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage. (609 aa)
DvirGJ19496Uncharacterized protein. (113 aa)
DvirGJ18611Uncharacterized protein. (1416 aa)
DvirGJ10048Uncharacterized protein, isoform A. (1395 aa)
DvirGJ10382DNA repair protein RAD51 homolog; Binds to single and double-stranded DNA and exhibits DNA- dependent ATPase activity. Underwinds duplex DNA. Belongs to the RecA family. RAD51 subfamily. (351 aa)
okrDNA repair and recombination protein RAD54-like; Involved in mitotic DNA repair and meiotic recombination. Functions in the recombinational DNA repair pathway. Essential for interhomolog gene conversion (GC), but may have a less important role in intersister GC than spn-A/Rad51. In the presence of DNA, spn-A/Rad51 enhances the ATPase activity of okr/Rad54 (By similarity). (786 aa)
DvirGJ15664DNA topoisomerase; Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. Belongs to the type IA topoisomerase family. (858 aa)
DvirGJ15211Uncharacterized protein, isoform A. (431 aa)
DvirGJ16256Uncharacterized protein. (79 aa)
DvirGJ16059Uncharacterized protein. (432 aa)
Your Current Organism:
Drosophila virilis
NCBI taxonomy Id: 7244
Other names: D. virilis
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