66 items (Drosophila virilis) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	DvirGJ15487	Tyrosine-protein kinase. (555 aa)
	DvirGJ17854	Tyrosine-protein kinase. (528 aa)
	DvirGJ21281	Uncharacterized protein, isoform B. (393 aa)
	bi	Bi, isoform C. (977 aa)
	dpp	Decapentaplegic, isoform B. (659 aa)
	DvirGJ10996	Uncharacterized protein, isoform B. (1345 aa)
	dos	Dos, isoform C. (911 aa)
	DvirGJ12360	Uncharacterized protein. (192 aa)
	DvirGJ12343	E3 ubiquitin-protein ligase; E3 ubiquitin-protein ligase that mediates ubiquitination and subsequent proteasomal degradation of target proteins. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates. (313 aa)
	sina	E3 ubiquitin-protein ligase; E3 ubiquitin-protein ligase that mediates ubiquitination and subsequent proteasomal degradation of target proteins. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates. (314 aa)
	DvirGJ11688	Uncharacterized protein. (1213 aa)
	DvirGJ13094	EGF-like domain-containing protein. (215 aa)
	DvirGJ13209	Uncharacterized protein. (192 aa)
	DvirGJ12092	Importin N-terminal domain-containing protein. (1049 aa)
	DvirGJ13345	Uncharacterized protein. (418 aa)
	argos	Argos. (482 aa)
	DvirGJ22079	PNT domain-containing protein. (172 aa)
	DvirGJ21569	Tyrosine-protein kinase. (947 aa)
	DvirGJ20054	Receptor protein-tyrosine kinase. (1438 aa)
	DvirGJ22384	BZIP domain-containing protein. (292 aa)
	DvirGJ22386	Uncharacterized protein, isoform A; Belongs to the 14-3-3 family. (248 aa)
	DvirGJ21098	Uncharacterized protein. (1373 aa)
	DvirGJ21350	Superoxide dismutase; Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the iron/manganese superoxide dismutase family. (217 aa)
	DvirGJ17518	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (375 aa)
	DvirGJ21884	Mitogen-activated protein kinase. (369 aa)
	DvirGJ12548	Profilin; Binds to actin and affects the structure of the cytoskeleton. At high concentrations, profilin prevents the polymerization of actin, whereas it enhances it at low concentrations. (126 aa)
	DvirGJ20581	Tyrosine-protein kinase. (801 aa)
	DvirGJ17687	Uncharacterized protein, isoform B. (738 aa)
	DvirGJ11119	Ig-like domain-containing protein. (912 aa)
	DvirGJ17774	Uncharacterized protein. (710 aa)
	DvirGJ17232	Serine/threonine-protein phosphatase. (309 aa)
	DvirGJ22971	UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family. (147 aa)
	DvirGJ22869	Uncharacterized protein, isoform A. (712 aa)
	DvirGJ23448	HMG box domain-containing protein. (1961 aa)
	pros	Pros. (1911 aa)
	DvirGJ23847	Uncharacterized protein. (185 aa)
	boss	Bride of sevenless, isoform A. (893 aa)
	DvirGJ23911	Uncharacterized protein, isoform B. (731 aa)
	ksr	Kinase suppressor of ras. (1003 aa)
	DvirGJ24161	Uncharacterized protein, isoform A. (513 aa)
	DvirGJ18839	Uncharacterized protein, isoform A; Belongs to the protein kinase superfamily. (397 aa)
	DvirGJ18758	Uncharacterized protein. (453 aa)
	DvirGJ18753	Uncharacterized protein, isoform B. (1204 aa)
	DvirGJ19194	Protein kinase domain-containing protein. (675 aa)
	DvirGJ11038	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (431 aa)
	DvirGJ10608	Uncharacterized protein, isoform A. (371 aa)
	kay	Transcription factor kayak; Developmentally regulated transcription factor AP-1 binds and recognizes the enhancer DNA sequence: 5'-TGA[CG]TCA-3'. May play a role in the function or determination of a particular subset of cells in the developing embryo. It is able to carry out its function either independently of or in conjunction with Jra (By similarity). (792 aa)
	DvirGJ10465	Uncharacterized protein. (195 aa)
	DvirGJ16598	Uncharacterized protein. (772 aa)
	DvirGJ16530	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (335 aa)
	csw	Corkscrew. (847 aa)
	DvirGJ18115	Uncharacterized protein. (235 aa)
	DvirGJ18140	Mitogen-activated protein kinase. (361 aa)
	DvirGJ18146	Uncharacterized protein. (1597 aa)
	DvirGJ18009	EGF-like domain-containing protein. (251 aa)
	DvirGJ18235	Uncharacterized protein, isoform A. (1062 aa)
	DvirGJ17880	Uncharacterized protein, isoform A. (935 aa)
	DvirGJ15727	Uncharacterized protein. (954 aa)
	DvirGJ14314	Uncharacterized protein, isoform A. (1580 aa)
	DvirGJ14531	Mitogen-activated protein kinase. (366 aa)
	DvirGJ14181	Uncharacterized protein. (295 aa)
	DvirGJ14161	MACPF domain-containing protein. (367 aa)
	DvirGJ15183	Uncharacterized protein. (405 aa)
	DvirGJ14851	Uncharacterized protein. (648 aa)
	DvirGJ15112	Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (551 aa)
	tll	Protein tailless; Orphan receptor that binds DNA as a monomer to hormone response elements (HRE) containing an extended core motif half-site sequence 5'-AAGTCA-3' in which the 5' flanking nucleotides participate in determining receptor specificity. This receptor binds to the consensus sequence [AG][AG]AAGTCAA. Plays a key role in the establishment of non-metameric domains at the anterior and posterior poles of the embryo. It may also play a role in the nervous system. The maternal terminal pathway activates the tll gene in the termini; TLL activity then represses segmentation and activ [...] (450 aa)

Your Current Organism:

Drosophila virilis

NCBI taxonomy Id: 7244
Other names: D. virilis

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
DvirGJ10465	DvirGJ12548	B4M627	B4LR73	Uncharacterized protein.	Profilin; Binds to actin and affects the structure of the cytoskeleton. At high concentrations, profilin prevents the polymerization of actin, whereas it enhances it at low concentrations.	0.503
DvirGJ10465	DvirGJ14531	B4M627	B4MBY2	Uncharacterized protein.	Mitogen-activated protein kinase.	0.489
DvirGJ10465	DvirGJ15487	B4M627	A0A0Q9VZD8	Uncharacterized protein.	Tyrosine-protein kinase.	0.473
DvirGJ10465	DvirGJ17854	B4M627	A0A0Q9W0V1	Uncharacterized protein.	Tyrosine-protein kinase.	0.473
DvirGJ10465	DvirGJ18140	B4M627	B4M8K4	Uncharacterized protein.	Mitogen-activated protein kinase.	0.489
DvirGJ10465	DvirGJ18146	B4M627	B4M8L2	Uncharacterized protein.	Uncharacterized protein.	0.564
DvirGJ10465	DvirGJ18753	B4M627	B4M207	Uncharacterized protein.	Uncharacterized protein, isoform B.	0.948
DvirGJ10465	DvirGJ18839	B4M627	B4M1J3	Uncharacterized protein.	Uncharacterized protein, isoform A; Belongs to the protein kinase superfamily.	0.465
DvirGJ10465	DvirGJ20054	B4M627	B4LLF8	Uncharacterized protein.	Receptor protein-tyrosine kinase.	0.539
DvirGJ10465	DvirGJ21884	B4M627	B4LR19	Uncharacterized protein.	Mitogen-activated protein kinase.	0.958
DvirGJ10608	DvirGJ14531	B4M5M7	B4MBY2	Uncharacterized protein, isoform A.	Mitogen-activated protein kinase.	0.443
DvirGJ10608	DvirGJ18140	B4M5M7	B4M8K4	Uncharacterized protein, isoform A.	Mitogen-activated protein kinase.	0.443
DvirGJ10608	DvirGJ18753	B4M5M7	B4M207	Uncharacterized protein, isoform A.	Uncharacterized protein, isoform B.	0.922
DvirGJ10608	DvirGJ19194	B4M5M7	B4M3D5	Uncharacterized protein, isoform A.	Protein kinase domain-containing protein.	0.922
DvirGJ10996	DvirGJ11038	A0A0Q9WAY0	B4M509	Uncharacterized protein, isoform B.	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	0.839
DvirGJ10996	DvirGJ16530	A0A0Q9WAY0	B4M728	Uncharacterized protein, isoform B.	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	0.988
DvirGJ10996	DvirGJ18758	A0A0Q9WAY0	B4M202	Uncharacterized protein, isoform B.	Uncharacterized protein.	0.729
DvirGJ10996	DvirGJ22384	A0A0Q9WAY0	B4LMG0	Uncharacterized protein, isoform B.	BZIP domain-containing protein.	0.424
DvirGJ10996	DvirGJ24161	A0A0Q9WAY0	B4M154	Uncharacterized protein, isoform B.	Uncharacterized protein, isoform A.	0.550
DvirGJ11038	DvirGJ10996	B4M509	A0A0Q9WAY0	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	Uncharacterized protein, isoform B.	0.839