STRINGSTRING
DvirGJ21177 DvirGJ21177 DvirGJ23383 DvirGJ23383 DvirGJ23359 DvirGJ23359 DvirGJ17528 DvirGJ17528 DvirGJ25993 DvirGJ25993 DvirGJ12497 DvirGJ12497 DvirGJ11260 DvirGJ11260 SAK SAK DvirGJ12318 DvirGJ12318 DvirGJ11579 DvirGJ11579 DvirGJ11574 DvirGJ11574 DvirGJ13780 DvirGJ13780 DvirGJ20298 DvirGJ20298 DvirGJ21534 DvirGJ21534 DvirGJ21535 DvirGJ21535 DvirGJ20054 DvirGJ20054 DvirGJ21062 DvirGJ21062 DvirGJ21350 DvirGJ21350 DvirGJ17518 DvirGJ17518 DvirGJ21884 DvirGJ21884 DvirGJ15454 DvirGJ15454 DvirGJ16866 DvirGJ16866 DvirGJ24689 DvirGJ24689 DvirGJ14148 DvirGJ14148 DvirGJ24290 DvirGJ24290 DvirGJ24313 DvirGJ24313 DvirGJ23839 DvirGJ23839 DvirGJ24114 DvirGJ24114 DvirGJ23092 DvirGJ23092 DvirGJ24128 DvirGJ24128 DvirGJ18839 DvirGJ18839 DvirGJ18762 DvirGJ18762 DvirGJ19060 DvirGJ19060 DvirGJ24711 DvirGJ24711 DvirGJ10573 DvirGJ10573 DvirGJ10658 DvirGJ10658 DvirGJ16598 DvirGJ16598 DvirGJ18140 DvirGJ18140 DvirGJ18146 DvirGJ18146 DvirGJ17881 DvirGJ17881 DvirGJ15670 DvirGJ15670 foxo foxo DvirGJ14531 DvirGJ14531 DvirGJ14183 DvirGJ14183 DvirGJ16300 DvirGJ16300 DvirGJ16301 DvirGJ16301 DvirGJ14868 DvirGJ14868 DvirGJ15118 DvirGJ15118 DvirGJ18513 DvirGJ18513
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
DvirGJ21177Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (599 aa)
DvirGJ23383Non-specific serine/threonine protein kinase. (695 aa)
DvirGJ23359Uncharacterized protein. (1415 aa)
DvirGJ17528Uncharacterized protein, isoform C. (597 aa)
DvirGJ25993Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (314 aa)
DvirGJ12497Protein kinase domain-containing protein. (807 aa)
DvirGJ11260Uncharacterized protein, isoform A. (354 aa)
SAKSerine/threonine-protein kinase PLK4; Serine/threonine-protein kinase that plays a central role in centriole duplication. Able to trigger procentriole formation on the surface of the mother centriole cylinder, using mother centriole as a platform, leading to the recruitment of centriole biogenesis proteins such as sas-6. When overexpressed, it is able to induce centrosome amplification through the simultaneous generation of multiple procentrioles adjoining each parental centriole during S phase. Centrosome amplification following overexpression can initiate tumorigenesis, highlighting [...] (781 aa)
DvirGJ12318Ubiquitin-like protein ATG12; Ubiquitin-like protein involved in autophagic vesicle formation; Belongs to the ATG12 family. (113 aa)
DvirGJ11579Uncharacterized protein. (575 aa)
DvirGJ11574Catalase; Occurs in almost all aerobically respiring organisms and serves to protect cells from the toxic effects of hydrogen peroxide. (506 aa)
DvirGJ13780Uncharacterized protein, isoform A. (202 aa)
DvirGJ20298Cyclin N-terminal domain-containing protein; Belongs to the cyclin family. (557 aa)
DvirGJ21534Uncharacterized protein. (639 aa)
DvirGJ21535Uncharacterized protein. (647 aa)
DvirGJ20054Receptor protein-tyrosine kinase. (1438 aa)
DvirGJ21062Ribosomal_L7Ae domain-containing protein. (160 aa)
DvirGJ21350Superoxide dismutase; Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the iron/manganese superoxide dismutase family. (217 aa)
DvirGJ17518Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (375 aa)
DvirGJ21884Mitogen-activated protein kinase. (369 aa)
DvirGJ15454WH1 domain-containing protein. (551 aa)
DvirGJ16866Deacetylase sirtuin-type domain-containing protein. (883 aa)
DvirGJ24689Uncharacterized protein. (513 aa)
DvirGJ14148Uncharacterized protein, isoform A. (347 aa)
DvirGJ24290Uncharacterized protein, isoform A; Belongs to the PI3/PI4-kinase family. (1076 aa)
DvirGJ24313Uncharacterized protein; Belongs to the cyclin family. (575 aa)
DvirGJ23839Protein kinase domain-containing protein. (735 aa)
DvirGJ24114Protein kinase domain-containing protein. (586 aa)
DvirGJ23092Mothers against decapentaplegic homolog. (769 aa)
DvirGJ24128Uncharacterized protein, isoform A; Belongs to the cyclin family. (578 aa)
DvirGJ18839Uncharacterized protein, isoform A; Belongs to the protein kinase superfamily. (397 aa)
DvirGJ18762Mothers against decapentaplegic homolog. (489 aa)
DvirGJ19060Uncharacterized protein, isoform A. (3142 aa)
DvirGJ24711Uncharacterized protein. (125 aa)
DvirGJ10573Methyltransf_25 domain-containing protein; Belongs to the class I-like SAM-binding methyltransferase superfamily. Protein arginine N-methyltransferase family. (388 aa)
DvirGJ10658Uncharacterized protein, isoform A; Belongs to the protein kinase superfamily. (467 aa)
DvirGJ16598Uncharacterized protein. (772 aa)
DvirGJ18140Mitogen-activated protein kinase. (361 aa)
DvirGJ18146Uncharacterized protein. (1597 aa)
DvirGJ17881Catalase domain-containing protein. (506 aa)
DvirGJ15670Non-specific serine/threonine protein kinase. (593 aa)
foxoForkhead box protein O; Transcription factor involved in the regulation of the insulin signaling pathway. Consistently activates both the downstream target Thord4EBP and the feedback control target InR. Involved in negative regulation of the cell cycle, modulating cell growth and proliferation. In response to cellular stresses, such as nutrient deprivation or increased levels of reactive oxygen species, foxo is activated and inhibits growth through the action of target genes such as Thor. Foxo activated in the adult fat body can regulate lifespan in adults; an insulin peptide itself m [...] (609 aa)
DvirGJ14531Mitogen-activated protein kinase. (366 aa)
DvirGJ14183F-box domain-containing protein. (584 aa)
DvirGJ16300Fork-head domain-containing protein. (343 aa)
DvirGJ16301Fork-head domain-containing protein. (466 aa)
DvirGJ14868Uncharacterized protein. (119 aa)
DvirGJ15118AMPKBI domain-containing protein. (334 aa)
DvirGJ18513Uncharacterized protein; Belongs to the peptidase C19 family. (1151 aa)
Your Current Organism:
Drosophila virilis
NCBI taxonomy Id: 7244
Other names: D. virilis
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