71 items (Drosophila virilis) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	CtBP	C-terminal binding protein, isoform C. (507 aa)
	DvirGJ17032	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1094 aa)
	DvirGJ23620	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1279 aa)
	DvirGJ18069	Uncharacterized protein, isoform B. (1396 aa)
	DvirGJ16546	Uncharacterized protein, isoform B. (448 aa)
	DvirGJ27036	Uncharacterized protein. (773 aa)
	DvirGJ22286	Uncharacterized protein, isoform C. (210 aa)
	DvirGJ16637	Casein kinase II subunit beta; Plays a complex role in regulating the basal catalytic activity of the alpha subunit; Belongs to the casein kinase 2 subunit beta family. (237 aa)
	DvirGJ11519	Presenilin; Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors. Belongs to the peptidase A22A family. (546 aa)
	DvirGJ12485	RING-type domain-containing protein. (131 aa)
	DvirGJ11825	Uncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family. (806 aa)
	DvirGJ12360	Uncharacterized protein. (192 aa)
	DvirGJ12343	E3 ubiquitin-protein ligase; E3 ubiquitin-protein ligase that mediates ubiquitination and subsequent proteasomal degradation of target proteins. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates. (313 aa)
	sina	E3 ubiquitin-protein ligase; E3 ubiquitin-protein ligase that mediates ubiquitination and subsequent proteasomal degradation of target proteins. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates. (314 aa)
	DvirGJ13077	Uncharacterized protein; Cell surface proteoglycan that bears heparan sulfate. Belongs to the glypican family. (642 aa)
	DvirGJ13689	Uncharacterized protein; Cell surface proteoglycan that bears heparan sulfate. Belongs to the glypican family. (785 aa)
	DvirGJ13209	Uncharacterized protein. (192 aa)
	DvirGJ20688	Uncharacterized protein, isoform A; Belongs to the SKP1 family. (162 aa)
	DvirGJ20064	Uncharacterized protein. (198 aa)
	DvirGJ22384	BZIP domain-containing protein. (292 aa)
	DvirGJ21239	Uncharacterized protein. (170 aa)
	DvirGJ20529	Casein kinase II subunit beta; Plays a complex role in regulating the basal catalytic activity of the alpha subunit; Belongs to the casein kinase 2 subunit beta family. (212 aa)
	DvirGJ22419	RING-type domain-containing protein. (117 aa)
	DvirGJ21295	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (379 aa)
	DvirGJ21016	Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (682 aa)
	DvirGJ21907	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (1014 aa)
	DvirGJ21884	Mitogen-activated protein kinase. (369 aa)
	DvirGJ20870	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (471 aa)
	DvirGJ20859	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (415 aa)
	wg	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (472 aa)
	DvirGJ17774	Uncharacterized protein. (710 aa)
	DvirGJ22991	Uncharacterized protein, isoform A; Belongs to the protein kinase superfamily. (354 aa)
	DvirGJ23553	RuvB-like helicase; Proposed core component of the chromatin remodeling Ino80 complex which is involved in transcriptional regulation, DNA replication and probably DNA repair. (456 aa)
	DvirGJ24306	Uncharacterized protein, isoform A. (110 aa)
	DvirGJ23847	Uncharacterized protein. (185 aa)
	DvirGJ23911	Uncharacterized protein, isoform B. (731 aa)
	DvirGJ23285	Uncharacterized protein. (566 aa)
	DvirGJ23092	Mothers against decapentaplegic homolog. (769 aa)
	DvirGJ24175	Uncharacterized protein. (2531 aa)
	DvirGJ18762	Mothers against decapentaplegic homolog. (489 aa)
	DvirGJ19060	Uncharacterized protein, isoform A. (3142 aa)
	DvirGJ19053	Uncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family. (619 aa)
	DvirGJ19138	Uncharacterized protein, isoform A. (836 aa)
	DvirGJ19194	Protein kinase domain-containing protein. (675 aa)
	DvirGJ18891	Uncharacterized protein; Belongs to the SKP1 family. (162 aa)
	DvirGJ10658	Uncharacterized protein, isoform A; Belongs to the protein kinase superfamily. (467 aa)
	DvirGJ10500	Serine/threonine-protein phosphatase. (630 aa)
	DvirGJ10465	Uncharacterized protein. (195 aa)
	DvirGJ10750	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (311 aa)
	DvirGJ10774	Uncharacterized protein, isoform A. (746 aa)
	DvirGJ16455	Uncharacterized protein. (228 aa)
	DvirGJ17044	Uncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family. (702 aa)
	DvirGJ18109	Uncharacterized protein, isoform C; Belongs to the protein kinase superfamily. Tyr protein kinase family. (686 aa)
	DvirGJ18248	Uncharacterized protein. (661 aa)
	DvirGJ17984	Uncharacterized protein. (583 aa)
	DvirGJ17913	Uncharacterized protein; Belongs to the protein kinase superfamily. (353 aa)
	DvirGJ15825	RING-type domain-containing protein. (108 aa)
	DvirGJ15916	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (343 aa)
	DvirGJ15665	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (343 aa)
	DvirGJ14208	Uncharacterized protein. (1063 aa)
	DvirGJ11189	Uncharacterized protein, isoform A; Belongs to the protein kinase superfamily. (336 aa)
	DvirGJ19682	Uncharacterized protein. (1671 aa)
	DvirGJ15240	Uncharacterized protein. (603 aa)
	DvirGJ16241	RING-type domain-containing protein. (149 aa)
	DvirGJ17750	Uncharacterized protein, isoform A; Belongs to the cullin family. (773 aa)
	DvirGJ18462	Uncharacterized protein. (615 aa)
	DvirGJ14779	Uncharacterized protein. (170 aa)
	DvirGJ15157	Uncharacterized protein. (1012 aa)
	DvirGJ15051	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (343 aa)
	DvirGJ20463	Uncharacterized protein, isoform B. (531 aa)
	fz	Frizzled; Receptor for Wnt proteins. Most of frizzled receptors are coupled to the beta-catenin canonical signaling pathway, which leads to the activation of disheveled proteins, inhibition of GSK-3 kinase, nuclear accumulation of beta-catenin and activation of Wnt target genes. A second signaling pathway involving PKC and calcium fluxes has been seen for some family members, but it is not yet clear if it represents a distinct pathway or if it can be integrated in the canonical pathway, as PKC seems to be required for Wnt-mediated inactivation of GSK-3 kinase. Both pathways seem to inv [...] (580 aa)

Your Current Organism:

Drosophila virilis

NCBI taxonomy Id: 7244
Other names: D. virilis

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CtBP	DvirGJ14208	A0A0Q9W1T3	B4MBX7	C-terminal binding protein, isoform C.	Uncharacterized protein.	0.735
CtBP	DvirGJ15240	A0A0Q9W1T3	B4MCY6	C-terminal binding protein, isoform C.	Uncharacterized protein.	0.544
CtBP	DvirGJ19060	A0A0Q9W1T3	B4M2X2	C-terminal binding protein, isoform C.	Uncharacterized protein, isoform A.	0.636
CtBP	DvirGJ19138	A0A0Q9W1T3	B4M333	C-terminal binding protein, isoform C.	Uncharacterized protein, isoform A.	0.814
CtBP	DvirGJ23285	A0A0Q9W1T3	B4LZ71	C-terminal binding protein, isoform C.	Uncharacterized protein.	0.463
CtBP	DvirGJ23911	A0A0Q9W1T3	B4LYS6	C-terminal binding protein, isoform C.	Uncharacterized protein, isoform B.	0.913
CtBP	DvirGJ24175	A0A0Q9W1T3	B4M181	C-terminal binding protein, isoform C.	Uncharacterized protein.	0.735
DvirGJ10465	DvirGJ15240	B4M627	B4MCY6	Uncharacterized protein.	Uncharacterized protein.	0.546
DvirGJ10465	DvirGJ17750	B4M627	B4ME02	Uncharacterized protein.	Uncharacterized protein, isoform A; Belongs to the cullin family.	0.411
DvirGJ10465	DvirGJ18462	B4M627	B4ME30	Uncharacterized protein.	Uncharacterized protein.	0.503
DvirGJ10465	DvirGJ19138	B4M627	B4M333	Uncharacterized protein.	Uncharacterized protein, isoform A.	0.458
DvirGJ10465	DvirGJ20064	B4M627	B4LLE0	Uncharacterized protein.	Uncharacterized protein.	0.616
DvirGJ10465	DvirGJ21884	B4M627	B4LR19	Uncharacterized protein.	Mitogen-activated protein kinase.	0.958
DvirGJ10465	DvirGJ22286	B4M627	A0A0Q9WFZ7	Uncharacterized protein.	Uncharacterized protein, isoform C.	0.613
DvirGJ10465	DvirGJ27036	B4M627	A0A0Q9WFP2	Uncharacterized protein.	Uncharacterized protein.	0.492
DvirGJ10500	DvirGJ14779	B4M5W9	B4MEG6	Serine/threonine-protein phosphatase.	Uncharacterized protein.	0.996
DvirGJ10500	DvirGJ17032	B4M5W9	A0A0Q9W852	Serine/threonine-protein phosphatase.	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes.	0.913
DvirGJ10500	DvirGJ21239	B4M5W9	B4LMJ8	Serine/threonine-protein phosphatase.	Uncharacterized protein.	0.975
DvirGJ10500	DvirGJ23620	B4M5W9	A0A0Q9W9U6	Serine/threonine-protein phosphatase.	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes.	0.903
DvirGJ10658	DvirGJ10774	B4M5W6	B4M6H3	Uncharacterized protein, isoform A; Belongs to the protein kinase superfamily.	Uncharacterized protein, isoform A.	0.959