(78 nodes) Motor neuron axon guidance network (Drosophila willistoni)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	DwilGK26929	Uncharacterized protein. (364 aa)
	DwilGK15199	Uncharacterized protein, isoform C. (989 aa)
	DwilGK27921	Uncharacterized protein. (102 aa)
	DwilGK27666	Uncharacterized protein. (349 aa)
	DwilGK27490	Ig-like domain-containing protein. (478 aa)
	DwilGK10614	Uncharacterized protein. (1072 aa)
	DwilGK20783	Uncharacterized protein. (1119 aa)
	DwilGK20743	Syndecan; Cell surface proteoglycan; Belongs to the syndecan proteoglycan family. (577 aa)
	DwilGK16805	Uncharacterized protein. (192 aa)
	DwilGK17431	LRRCT domain-containing protein. (751 aa)
	DwilGK17433	LRRCT domain-containing protein. (787 aa)
	DwilGK17453	Uncharacterized protein. (2753 aa)
	DwilGK16744	Uncharacterized protein; Cell surface proteoglycan that bears heparan sulfate. Belongs to the glypican family. (616 aa)
	DwilGK16646	Uncharacterized protein. (802 aa)
	DwilGK16645	LAM_G_DOMAIN domain-containing protein. (223 aa)
	DwilNT1	Neurotrophin 1. (1010 aa)
	DwilGK17627	Spaetzle domain-containing protein. (399 aa)
	DwilGK17117	PID domain-containing protein. (2484 aa)
	DwilGK19679	Uncharacterized protein. (701 aa)
	Dwileve	Eve. (364 aa)
	DwilGK21638	GK21638. (652 aa)
	DwilGK21847	GK21847. (1406 aa)
	DwilGK21950	GK21950; Belongs to the protein kinase superfamily. (294 aa)
	DwilGK15811	Uncharacterized protein. (1452 aa)
	DwilGK15621	ZnMc domain-containing protein. (571 aa)
	DwilGK19778	Uncharacterized protein. (1623 aa)
	DwilGK23873	Uncharacterized protein. (410 aa)
	DwilGK23799	Ig-like domain-containing protein. (286 aa)
	DwilGK23894	Uncharacterized protein. (544 aa)
	DwilGK15473	Uncharacterized protein. (1097 aa)
	DwilGK14922	Uncharacterized protein. (1875 aa)
	DwilGK20085	Uncharacterized protein. (1688 aa)
	DwilGK20236	NUC205 domain-containing protein. (653 aa)
	DwilGK18164	BHLH domain-containing protein. (246 aa)
	DwilGK18108	Ig-like domain-containing protein. (423 aa)
	DwilGK24728	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (497 aa)
	DwilGK24261	Uncharacterized protein. (548 aa)
	DwilGK24768	Ig-like domain-containing protein. (504 aa)
	DwilGK24239	Uncharacterized protein. (404 aa)
	DwilGK16488	Uncharacterized protein. (3076 aa)
	DwilGK12556	POU domain protein. (745 aa)
	DwilGK25717	Guanylate cyclase. (1547 aa)
	DwilGK12461	Uncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family. (826 aa)
	DwilGK20502	GK20502. (192 aa)
	DwilGK12317	Stork_head domain-containing protein. (1096 aa)
	DwilGK12287	Carboxylic ester hydrolase; Belongs to the type-B carboxylesterase/lipase family. (560 aa)
	DwilGK18750	Sema domain-containing protein; Belongs to the semaphorin family. (1105 aa)
	DwilGK18671	Uncharacterized protein. (772 aa)
	DwilGK18669	COesterase domain-containing protein. (1043 aa)
	DwilGK11980	Uncharacterized protein. (787 aa)
	DwilGK12058	Uncharacterized protein. (1232 aa)
	DwilGK12094	Ig-like domain-containing protein. (328 aa)
	DwilGK10886	Uncharacterized protein, isoform D. (2396 aa)
	DwilGK11458	Uncharacterized protein. (403 aa)
	DwilGK11457	Uncharacterized protein. (469 aa)
	DwilGK10866	Ig-like domain-containing protein. (356 aa)
	DwilGK10863	Ig-like domain-containing protein. (300 aa)
	DwilGK12214	Ig-like domain-containing protein. (346 aa)
	DwilGK11337	Uncharacterized protein. (900 aa)
	DwilGK25195	Uncharacterized protein. (2007 aa)
	DwilGK25863	Uncharacterized protein, isoform A. (1304 aa)
	DwilGK10088	Uncharacterized protein. (302 aa)
	DwilGK24915	Uncharacterized protein. (3117 aa)
	DwilGK25610	Uncharacterized protein. (626 aa)
	DwilGK13667	Sema domain-containing protein. (2061 aa)
	DwilGK13512	Uncharacterized protein. (1148 aa)
	DwilGK12883	Uncharacterized protein. (728 aa)
	DwilGK13873	Ig-like domain-containing protein. (447 aa)
	DwilGK12791	Uncharacterized protein. (500 aa)
	DwilGK14033	Metalloendopeptidase. (947 aa)
	DwilGK23137	Uncharacterized protein. (192 aa)
	DwilGK23041	PDZ domain-containing protein. (352 aa)
	DwilGK17610	Uncharacterized protein. (865 aa)
	DwilGK15168	Uncharacterized protein. (1001 aa)
	DwilGK18468	Uncharacterized protein. (834 aa)
	DwilGK18481	Uncharacterized protein. (743 aa)
	DwilGK17279	Uncharacterized protein. (2653 aa)
	DwilGK17312	Uncharacterized protein. (191 aa)

Your Current Organism:

Drosophila willistoni

NCBI taxonomy Id: 7260
Other names: D. willistoni

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structured XML interaction data, according to the 'PSI-MI' data standard

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node degree of proteins in your network (given the current score cut-off)

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a flat-file format describing the coordinates and colors of nodes in the network

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MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
DwilGK10614	DwilGK15168	B4MJ18	B4NPH8	Uncharacterized protein.	Uncharacterized protein.	0.807
DwilGK10614	DwilGK16744	B4MJ18	B4MMD2	Uncharacterized protein.	Uncharacterized protein; Cell surface proteoglycan that bears heparan sulfate. Belongs to the glypican family.	0.857
DwilGK10614	DwilGK18468	B4MJ18	B4NPQ4	Uncharacterized protein.	Uncharacterized protein.	0.835
DwilGK10614	DwilGK18481	B4MJ18	B4NPQ6	Uncharacterized protein.	Uncharacterized protein.	0.751
DwilGK10886	DwilGK17312	B4N9K6	B4NQ65	Uncharacterized protein, isoform D.	Uncharacterized protein.	0.459
DwilGK11337	DwilGK12094	B4NAP3	B4N8N3	Uncharacterized protein.	Ig-like domain-containing protein.	0.457
DwilGK12058	DwilGK25863	B4N8H3	B4NCI8	Uncharacterized protein.	Uncharacterized protein, isoform A.	0.518
DwilGK12094	DwilGK11337	B4N8N3	B4NAP3	Ig-like domain-containing protein.	Uncharacterized protein.	0.457
DwilGK12461	DwilGK21638	B4N4Q2	B4MPB5	Uncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family.	GK21638.	0.918
DwilGK12461	DwilGK24728	B4N4Q2	B4MZW5	Uncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family.	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	0.919
DwilGK12461	DwilGK25610	B4N4Q2	B4NEA1	Uncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family.	Uncharacterized protein.	0.985
DwilGK12883	DwilGK23894	B4NJ90	B4MTS3	Uncharacterized protein.	Uncharacterized protein.	0.477
DwilGK12883	Dwileve	B4NJ90	B4MP83	Uncharacterized protein.	Eve.	0.403
DwilGK13512	DwilGK16744	B4NIN2	B4MMD2	Uncharacterized protein.	Uncharacterized protein; Cell surface proteoglycan that bears heparan sulfate. Belongs to the glypican family.	0.513
DwilGK13667	DwilGK15811	B4NHI8	B4MRD7	Sema domain-containing protein.	Uncharacterized protein.	0.491
DwilGK13667	DwilGK16805	B4NHI8	B4ML79	Sema domain-containing protein.	Uncharacterized protein.	0.533
DwilGK13667	DwilGK17312	B4NHI8	B4NQ65	Sema domain-containing protein.	Uncharacterized protein.	0.533
DwilGK13667	DwilGK18750	B4NHI8	B4N7S2	Sema domain-containing protein.	Sema domain-containing protein; Belongs to the semaphorin family.	0.869
DwilGK13667	DwilGK19778	B4NHI8	B4MT44	Sema domain-containing protein.	Uncharacterized protein.	0.491
DwilGK13667	DwilGK20502	B4NHI8	B4N547	Sema domain-containing protein.	GK20502.	0.533