(49 nodes) Regulation of BMP signaling pathway network (Drosophila willistoni)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	DwilGK19733	Uncharacterized protein. (1193 aa)
	DwilGK27889	Uncharacterized protein. (311 aa)
	DwilGK26979	Senescence domain-containing protein. (284 aa)
	DwilGK27177	CULLIN_2 domain-containing protein; Belongs to the cullin family. (763 aa)
	DwilGK18688	Uncharacterized protein. (90 aa)
	DwilGK27666	Uncharacterized protein. (349 aa)
	DwilGK10721	Uncharacterized protein. (1075 aa)
	DwilGK20745	Uncharacterized protein. (664 aa)
	DwilGK17391	Uncharacterized protein. (827 aa)
	DwilGK17392	Uncharacterized protein, isoform B. (873 aa)
	DwilGK16744	Uncharacterized protein; Cell surface proteoglycan that bears heparan sulfate. Belongs to the glypican family. (616 aa)
	DwilGK16632	HECT domain-containing protein. (1064 aa)
	DwilGK21539	GK21539. (809 aa)
	DwilGK21866	GK21866. (699 aa)
	DwilGK21928	GK21928. (662 aa)
	DwilGK21959	GK21959. (631 aa)
	DwilGK19972	Uncharacterized protein. (251 aa)
	DwilGK23962	c-SKI_SMAD_bind domain-containing protein. (670 aa)
	DwilGK23980	VWFC domain-containing protein. (695 aa)
	DwilGK14711	Uncharacterized protein; Belongs to the DEAD box helicase family. (403 aa)
	DwilGK14661	Uncharacterized protein. (385 aa)
	DwilGK15486	Uncharacterized protein. (1136 aa)
	DwilGK22046	PAW domain-containing protein. (639 aa)
	DwilGK18192	Mitogen-activated protein kinase. (368 aa)
	DwilGK24272	COesterase domain-containing protein. (962 aa)
	Dwilcbt	Cabut. (444 aa)
	DwilGK16309	Uncharacterized protein, isoform A. (243 aa)
	Dwilbrk	Brinker. (740 aa)
	DwilGK25717	Guanylate cyclase. (1547 aa)
	DwilGK12021	DEP domain-containing protein. (969 aa)
	DwilGK10539	IGFBP N-terminal domain-containing protein. (276 aa)
	DwilGK11509	MIT domain-containing protein. (555 aa)
	DwilGK11861	Uncharacterized protein. (1467 aa)
	DwilGK10058	Uncharacterized protein, isoform A. (1035 aa)
	DwilGK10185	LEM domain-containing protein. (321 aa)
	DwilGK10190	Protein kinase domain-containing protein. (802 aa)
	Dwilsog	Short gastrulation. (950 aa)
	DwilGK17722	Uncharacterized protein. (285 aa)
	DwilGK13167	Uncharacterized protein; Belongs to the LIMR family. (528 aa)
	DwilGK13606	c-SKI_SMAD_bind domain-containing protein. (853 aa)
	DwilGK12979	Uncharacterized protein. (2781 aa)
	DwilGK13383	Mothers against decapentaplegic homolog. (634 aa)
	DwilGK12790	LEM domain-containing protein. (408 aa)
	DwilGK12789	LEM domain-containing protein. (479 aa)
	DwilGK14033	Metalloendopeptidase. (947 aa)
	DwilGK14034	Metalloendopeptidase. (912 aa)
	DwilGK23042	Uncharacterized protein, isoform C. (1069 aa)
	DwilGK23240	LEM domain-containing protein. (419 aa)
	DwilGK15070	Ig-like domain-containing protein. (915 aa)

Your Current Organism:

Drosophila willistoni

NCBI taxonomy Id: 7260
Other names: D. willistoni

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
DwilGK10721	DwilGK13383	B4MIS4	B4NJZ6	Uncharacterized protein.	Mothers against decapentaplegic homolog.	0.980
DwilGK11509	DwilGK14661	B4N9B4	B4MV91	MIT domain-containing protein.	Uncharacterized protein.	0.488
DwilGK11861	DwilGK15070	B4NBA8	B4NPJ3	Uncharacterized protein.	Ig-like domain-containing protein.	0.427
DwilGK11861	DwilGK21539	B4NBA8	B4MPU0	Uncharacterized protein.	GK21539.	0.457
DwilGK13383	DwilGK10721	B4NJZ6	B4MIS4	Mothers against decapentaplegic homolog.	Uncharacterized protein.	0.980
DwilGK13383	DwilGK23962	B4NJZ6	B4MU33	Mothers against decapentaplegic homolog.	c-SKI_SMAD_bind domain-containing protein.	0.518
DwilGK13383	DwilGK27889	B4NJZ6	A0A0Q9WRR2	Mothers against decapentaplegic homolog.	Uncharacterized protein.	0.518
DwilGK13383	Dwilsog	B4NJZ6	B4NEC5	Mothers against decapentaplegic homolog.	Short gastrulation.	0.540
DwilGK14033	Dwilsog	B4NL40	B4NEC5	Metalloendopeptidase.	Short gastrulation.	0.742
DwilGK14034	DwilGK20745	B4NL41	B4MJU7	Metalloendopeptidase.	Uncharacterized protein.	0.463
DwilGK14034	DwilGK27666	B4NL41	A0A0Q9X5B9	Metalloendopeptidase.	Uncharacterized protein.	0.400
DwilGK14034	Dwilsog	B4NL41	B4NEC5	Metalloendopeptidase.	Short gastrulation.	0.850
DwilGK14661	DwilGK11509	B4MV91	B4N9B4	Uncharacterized protein.	MIT domain-containing protein.	0.488
DwilGK14661	DwilGK26979	B4MV91	A0A0Q9WUP0	Uncharacterized protein.	Senescence domain-containing protein.	0.488
DwilGK15070	DwilGK11861	B4NPJ3	B4NBA8	Ig-like domain-containing protein.	Uncharacterized protein.	0.427
DwilGK16309	DwilGK23042	B4N1H8	B4NMR4	Uncharacterized protein, isoform A.	Uncharacterized protein, isoform C.	0.919
DwilGK19972	DwilGK20745	B4MSH1	B4MJU7	Uncharacterized protein.	Uncharacterized protein.	0.573
DwilGK19972	Dwilsog	B4MSH1	B4NEC5	Uncharacterized protein.	Short gastrulation.	0.737
DwilGK20745	DwilGK14034	B4MJU7	B4NL41	Uncharacterized protein.	Metalloendopeptidase.	0.463
DwilGK20745	DwilGK19972	B4MJU7	B4MSH1	Uncharacterized protein.	Uncharacterized protein.	0.573