(9 nodes) Wound healing, spreading of cells network (Drosophila willistoni)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	DwilGK16738	Uncharacterized protein. (1787 aa)
	DwilGK23859	Receptor protein-tyrosine kinase. (1496 aa)
	DwilGK16524	PDGF_2 domain-containing protein; Belongs to the PDGF/VEGF growth factor family. (329 aa)
	DwilGK11389	Uncharacterized protein. (4031 aa)
	DwilGK25517	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (337 aa)
	DwilGK25671	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (336 aa)
	DwilGK12444	Mitogen-activated protein kinase. (371 aa)
	DwilGK13262	Non-specific serine/threonine protein kinase. (531 aa)
	DwilGK13260	Non-specific serine/threonine protein kinase. (674 aa)

Your Current Organism:

Drosophila willistoni

NCBI taxonomy Id: 7260
Other names: D. willistoni

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
DwilGK12444	DwilGK25671	B4NGJ8	B4NEN3	Mitogen-activated protein kinase.	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	0.742
DwilGK13260	DwilGK13262	B4NL10	B4NL09	Non-specific serine/threonine protein kinase.	Non-specific serine/threonine protein kinase.	0.900
DwilGK13262	DwilGK13260	B4NL09	B4NL10	Non-specific serine/threonine protein kinase.	Non-specific serine/threonine protein kinase.	0.900
DwilGK13262	DwilGK25671	B4NL09	B4NEN3	Non-specific serine/threonine protein kinase.	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	0.400
DwilGK16524	DwilGK23859	B4N2K6	B4MTK0	PDGF_2 domain-containing protein; Belongs to the PDGF/VEGF growth factor family.	Receptor protein-tyrosine kinase.	0.979
DwilGK23859	DwilGK16524	B4MTK0	B4N2K6	Receptor protein-tyrosine kinase.	PDGF_2 domain-containing protein; Belongs to the PDGF/VEGF growth factor family.	0.979
DwilGK25671	DwilGK12444	B4NEN3	B4NGJ8	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	Mitogen-activated protein kinase.	0.742
DwilGK25671	DwilGK13262	B4NEN3	B4NL09	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	Non-specific serine/threonine protein kinase.	0.400