(117 nodes) Digestive tract development network (Drosophila willistoni)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	DwilGK27417	Homeobox domain-containing protein. (295 aa)
	DwilGK27594	Uncharacterized protein. (166 aa)
	DwilGK12202	Uncharacterized protein, isoform B. (718 aa)
	DwilGK10742	Uncharacterized protein, isoform B. (1155 aa)
	DwilGK24334	Uncharacterized protein, isoform C. (1220 aa)
	DwilGK27299	Uncharacterized protein. (331 aa)
	DwilGK12243	Uncharacterized protein, isoform B. (778 aa)
	DwilGK11226	Uncharacterized protein, isoform C. (1617 aa)
	DwilGK12150	Uncharacterized protein, isoform B. (2394 aa)
	DwilGK17716	ULD domain-containing protein. (100 aa)
	DwilGK10721	Uncharacterized protein. (1075 aa)
	DwilGK10731	Uncharacterized protein; Belongs to the protein kinase superfamily. Tyr protein kinase family. (1759 aa)
	DwilGK10632	Uncharacterized protein. (844 aa)
	DwilGK10766	Receptor protein-tyrosine kinase. (1386 aa)
	DwilGK23597	Uncharacterized protein. (544 aa)
	DwilGK20806	Uncharacterized protein. (805 aa)
	DwilGK20672	Uncharacterized protein. (722 aa)
	DwilGK20953	Uncharacterized protein. (2456 aa)
	DwilGK17143	HMG box domain-containing protein. (420 aa)
	DwilGK17145	HMG box domain-containing protein. (368 aa)
	DwilGK16939	Uncharacterized protein, isoform A. (162 aa)
	DwilGK17519	BHLH domain-containing protein. (213 aa)
	Dwilrho	Rhomboid; Belongs to the peptidase S54 family. (361 aa)
	DwilGK17308	Uncharacterized protein. (597 aa)
	Dwilvn	Vein. (481 aa)
	DwilGK16620	Uncharacterized protein. (1645 aa)
	DwilGK19547	BHLH domain-containing protein. (515 aa)
	DwilGK19542	Uncharacterized protein. (2185 aa)
	DwilGK21719	GK21719. (510 aa)
	DwilGK21996	GK21996. (840 aa)
	DwilGK15831	MADS-box domain-containing protein. (549 aa)
	DwilGK15709	TGF_BETA_2 domain-containing protein. (457 aa)
	DwilGK15972	Uncharacterized protein. (886 aa)
	DwilGK19868	Uncharacterized protein. (470 aa)
	DwilGK23859	Receptor protein-tyrosine kinase. (1496 aa)
	DwilGK14650	Uncharacterized protein. (794 aa)
	DwilGK15475	Uncharacterized protein. (416 aa)
	DwilGK15478	Uncharacterized protein. (526 aa)
	DwilGK14638	Uncharacterized protein. (74 aa)
	DwilGK14633	Rhomboid domain-containing protein. (201 aa)
	DwilGK15035	Uncharacterized protein. (3390 aa)
	DwilGK15225	RING-type domain-containing protein. (429 aa)
	DwilGK14914	Homeobox domain-containing protein. (415 aa)
	DwilGK14834	Uncharacterized protein. (707 aa)
	DwilGK20151	Uncharacterized protein. (1014 aa)
	DwilGK20296	Uncharacterized protein. (4641 aa)
	DwilGK22071	Uncharacterized protein. (1400 aa)
	DwilGK22046	PAW domain-containing protein. (639 aa)
	DwilGK18251	Uncharacterized protein. (408 aa)
	DwilGK24332	Uncharacterized protein. (578 aa)
	Dwilwg	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (477 aa)
	DwilGK24152	Collagen IV NC1 domain-containing protein. (1893 aa)
	DwilGK24856	Collagen IV NC1 domain-containing protein. (1784 aa)
	DwilGK16333	Uncharacterized protein. (693 aa)
	DwilGK16157	Uncharacterized protein. (1952 aa)
	DwilGK16477	Uncharacterized protein. (1283 aa)
	DwilGK16516	Uncharacterized protein. (176 aa)
	DwilGK16524	PDGF_2 domain-containing protein; Belongs to the PDGF/VEGF growth factor family. (329 aa)
	DwilGK10771	ULD domain-containing protein. (197 aa)
	DwilGK21236	Uncharacterized protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1011 aa)
	DwilGK12519	Uncharacterized protein. (710 aa)
	DwilGK12696	Uncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family. (423 aa)
	DwilGK25266	Uncharacterized protein. (717 aa)
	DwilGK12461	Uncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family. (826 aa)
	DwilGK20502	GK20502. (192 aa)
	DwilGK20555	GK20555. (812 aa)
	DwilGK24109	Uncharacterized protein. (455 aa)
	DwilGK17923	ETF domain-containing protein. (330 aa)
	DwilGK17776	Uncharacterized protein; Belongs to the cytochrome P450 family. (492 aa)
	DwilGK18055	DH domain-containing protein. (628 aa)
	DwilGK18056	Uncharacterized protein. (909 aa)
	DwilGK24122	Uncharacterized protein. (767 aa)
	DwilGK21105	Uncharacterized protein; Belongs to the intermediate filament family. (623 aa)
	DwilGK18714	Uncharacterized protein. (964 aa)
	DwilGK18686	Condensin complex subunit 2; Regulatory subunit of the condensin complex, a complex required for conversion of interphase chromatin into mitotic-like condense chromosomes. (773 aa)
	DwilGK18663	Uncharacterized protein. (910 aa)
	DwilGK16538	Uncharacterized protein. (255 aa)
	DwilGK10997	Fork-head domain-containing protein. (672 aa)
	DwilGK11542	Uncharacterized protein. (552 aa)
	DwilGK11606	Uncharacterized protein. (346 aa)
	DwilGK10836	Homeobox domain-containing protein. (650 aa)
	DwilGK10826	Homeobox domain-containing protein. (413 aa)
	DwilGK10824	Homeobox domain-containing protein. (395 aa)
	DwilGK25800	Uncharacterized protein; Belongs to the protein kinase superfamily. Tyr protein kinase family. (1046 aa)
	DwilGK25609	Uncharacterized protein. (1221 aa)
	inx	Innexin; Structural component of the gap junctions. Belongs to the pannexin family. (367 aa)
	DwilGK25655	Integrin beta; Belongs to the integrin beta chain family. (855 aa)
	DwilGK25272	BHLH domain-containing protein. (571 aa)
	DwilGK25271	BHLH domain-containing protein. (280 aa)
	DwilGK25269	BHLH domain-containing protein. (236 aa)
	DwilGK21291	Homeobox domain-containing protein. (415 aa)
	DwilGK22329	Uncharacterized protein. (2134 aa)
	DwilGK22843	GATA-type domain-containing protein. (758 aa)
	DwilGK22636	HATPase_c domain-containing protein. (790 aa)
	DwilGK22722	Signal transducer and activator of transcription. (845 aa)
	DwilGK12444	Mitogen-activated protein kinase. (371 aa)
	DwilGK12476	BHLH domain-containing protein. (696 aa)
	DwilGK13619	Uncharacterized protein, isoform A. (775 aa)
	DwilGK12979	Uncharacterized protein. (2781 aa)
	DwilGK13743	SPARC_Ca_bdg domain-containing protein. (302 aa)
	DwilGK14377	Uncharacterized protein. (502 aa)
	DwilGK13851	Homeobox domain-containing protein. (528 aa)
	DwilGK13853	Uncharacterized protein, isoform A. (590 aa)
	DwilGK13383	Mothers against decapentaplegic homolog. (634 aa)
	DwilGK14450	Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (511 aa)
	DwilGK12791	Uncharacterized protein. (500 aa)
	DwilGK14502	Homeobox domain-containing protein. (424 aa)
	DwilGK13254	GATA-type domain-containing protein. (732 aa)
	DwilGK13239	Uncharacterized protein. (674 aa)
	DwilGK13231	BZIP domain-containing protein. (1463 aa)
	DwilGK10527	Uncharacterized protein; Belongs to the cytochrome P450 family. (534 aa)
	DwilGK23137	Uncharacterized protein. (192 aa)
	DwilGK22947	Uncharacterized protein; Cadherins are calcium-dependent cell adhesion proteins. (1505 aa)
	DwilGK14819	Kinesin motor domain-containing protein; Belongs to the integrin alpha chain family. (1967 aa)
	DwilGK18412	Integrin_alpha2 domain-containing protein; Belongs to the integrin alpha chain family. (1355 aa)
	DwilGK17279	Uncharacterized protein. (2653 aa)
	DwilGK10790	Homeobox domain-containing protein. (314 aa)

Your Current Organism:

Drosophila willistoni

NCBI taxonomy Id: 7260
Other names: D. willistoni

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
DwilGK10527	DwilGK12791	B4NM34	B4NK58	Uncharacterized protein; Belongs to the cytochrome P450 family.	Uncharacterized protein.	0.943
DwilGK10721	DwilGK10766	B4MIS4	B4MJ19	Uncharacterized protein.	Receptor protein-tyrosine kinase.	0.847
DwilGK10721	DwilGK11606	B4MIS4	B4N9F0	Uncharacterized protein.	Uncharacterized protein.	0.454
DwilGK10721	DwilGK13383	B4MIS4	B4NJZ6	Uncharacterized protein.	Mothers against decapentaplegic homolog.	0.980
DwilGK10721	DwilGK14450	B4MIS4	B4NK20	Uncharacterized protein.	Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.	0.663
DwilGK10721	DwilGK23137	B4MIS4	B4NMF8	Uncharacterized protein.	Uncharacterized protein.	0.706
DwilGK10731	DwilGK10766	B4MIU7	B4MJ19	Uncharacterized protein; Belongs to the protein kinase superfamily. Tyr protein kinase family.	Receptor protein-tyrosine kinase.	0.719
DwilGK10731	DwilGK12444	B4MIU7	B4NGJ8	Uncharacterized protein; Belongs to the protein kinase superfamily. Tyr protein kinase family.	Mitogen-activated protein kinase.	0.406
DwilGK10731	DwilGK15709	B4MIU7	B4MRQ3	Uncharacterized protein; Belongs to the protein kinase superfamily. Tyr protein kinase family.	TGF_BETA_2 domain-containing protein.	0.436
DwilGK10731	DwilGK22722	B4MIU7	B4NFX0	Uncharacterized protein; Belongs to the protein kinase superfamily. Tyr protein kinase family.	Signal transducer and activator of transcription.	0.541
DwilGK10731	DwilGK25609	B4MIU7	B4NE99	Uncharacterized protein; Belongs to the protein kinase superfamily. Tyr protein kinase family.	Uncharacterized protein.	0.513
DwilGK10731	DwilGK25655	B4MIU7	B4NEJ2	Uncharacterized protein; Belongs to the protein kinase superfamily. Tyr protein kinase family.	Integrin beta; Belongs to the integrin beta chain family.	0.494
DwilGK10731	DwilGK25800	B4MIU7	B4NC66	Uncharacterized protein; Belongs to the protein kinase superfamily. Tyr protein kinase family.	Uncharacterized protein; Belongs to the protein kinase superfamily. Tyr protein kinase family.	0.553
DwilGK10742	DwilGK10766	A0A0Q9WXB0	B4MJ19	Uncharacterized protein, isoform B.	Receptor protein-tyrosine kinase.	0.402
DwilGK10766	DwilGK10721	B4MJ19	B4MIS4	Receptor protein-tyrosine kinase.	Uncharacterized protein.	0.847
DwilGK10766	DwilGK10731	B4MJ19	B4MIU7	Receptor protein-tyrosine kinase.	Uncharacterized protein; Belongs to the protein kinase superfamily. Tyr protein kinase family.	0.719
DwilGK10766	DwilGK10742	B4MJ19	A0A0Q9WXB0	Receptor protein-tyrosine kinase.	Uncharacterized protein, isoform B.	0.402
DwilGK10766	DwilGK11542	B4MJ19	B4N8Y0	Receptor protein-tyrosine kinase.	Uncharacterized protein.	0.483
DwilGK10766	DwilGK13619	B4MJ19	B4NHI3	Receptor protein-tyrosine kinase.	Uncharacterized protein, isoform A.	0.459
DwilGK10766	DwilGK15035	B4MJ19	B4MVL9	Receptor protein-tyrosine kinase.	Uncharacterized protein.	0.402