(56 nodes) Developmental cell growth network (Drosophila willistoni)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	DwilGK10424	Uncharacterized protein, isoform A. (1284 aa)
	DwilGK12696	Uncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family. (423 aa)
	DwilGK25814	Mitogen-activated protein kinase kinase kinase. (1017 aa)
	DwilGK11726	Uncharacterized protein. (146 aa)
	DwilGK11933	RING-type domain-containing protein. (283 aa)
	DwilGK10461	Uncharacterized protein, isoform A. (465 aa)
	DwilGK12570	RING-type domain-containing protein. (301 aa)
	DwilGK24804	Uncharacterized protein. (1226 aa)
	DwilGK24612	Uncharacterized protein. (735 aa)
	DwilGK18219	Uncharacterized protein; Cadherins are calcium-dependent cell adhesion proteins. (1709 aa)
	DwilGK18218	Uncharacterized protein; Cadherins are calcium-dependent cell adhesion proteins. (1755 aa)
	DwilGK17312	Uncharacterized protein. (191 aa)
	DwilGK13061	Tyrosine-protein phosphatase; Belongs to the protein-tyrosine phosphatase family. Non- receptor class subfamily. (972 aa)
	DwilGK15519	Uncharacterized protein. (720 aa)
	DwilGK14922	Uncharacterized protein. (1875 aa)
	DwilGK14984	Uncharacterized protein. (219 aa)
	DwilGK15458	Uncharacterized protein; Belongs to the protein kinase superfamily. (353 aa)
	DwilGK14803	UBR-type domain-containing protein. (5425 aa)
	DwilGK15250	Uncharacterized protein. (1387 aa)
	DwilGK14890	WH2 domain-containing protein. (656 aa)
	DwilGK23923	Transporter; Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family. (1007 aa)
	DwilGK20120	Uncharacterized protein. (1248 aa)
	DwilGK19766	Uncharacterized protein, isoform C. (1472 aa)
	DwilGK19910	Uncharacterized protein. (1167 aa)
	DwilGK15749	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (356 aa)
	DwilGK22019	GK22019. (2234 aa)
	DwilGK18424	Uncharacterized protein, isoform A; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (2214 aa)
	DwilGK17943	BTB domain-containing protein; Belongs to the potassium channel family. (639 aa)
	DwilGK23207	CDT1 domain-containing protein. (721 aa)
	DwilGK14027	Uncharacterized protein. (527 aa)
	DwilGK13429	Uncharacterized protein. (197 aa)
	DwilGK12879	Uncharacterized protein. (2795 aa)
	DwilGK13612	Uncharacterized protein. (1761 aa)
	DwilGK12444	Mitogen-activated protein kinase. (371 aa)
	DwilGK25249	Protein kinase domain-containing protein. (1146 aa)
	DwilGK25610	Uncharacterized protein. (626 aa)
	DwilGK25863	Uncharacterized protein, isoform A. (1304 aa)
	kay	Transcription factor kayak; Developmentally regulated transcription factor AP-1 binds and recognizes the enhancer DNA sequence: 5'-TGA[CG]TCA-3'. May play a role in the function or determination of a particular subset of cells in the developing embryo. It is able to carry out its function either independently of or in conjunction with Jra (By similarity). (620 aa)
	DwilGK11836	Fibroblast growth factor receptor. (758 aa)
	DwilGK12078	Uncharacterized protein. (1910 aa)
	DwilGK24225	Uncharacterized protein. (1331 aa)
	DwilGK20380	GK20380. (907 aa)
	DwilGK20502	GK20502. (192 aa)
	DwilGK12461	Uncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family. (826 aa)
	DwilGK21945	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (997 aa)
	DwilGK21839	GK21839. (1812 aa)
	DwilGK21754	GK21754. (1401 aa)
	DwilGK17359	Protein kinase domain-containing protein. (861 aa)
	DwilGK17037	Uncharacterized protein. (1171 aa)
	DwilGK20889	Integrin_alpha2 domain-containing protein; Belongs to the integrin alpha chain family. (1114 aa)
	DwilGK10354	Uncharacterized protein. (585 aa)
	DwilGK10907	Uncharacterized protein, isoform B. (467 aa)
	DwilGK24236	Death domain-containing protein. (1676 aa)
	DwilGK12160	Uncharacterized protein, isoform C. (1874 aa)
	DwilGK27494	Uncharacterized protein, isoform B. (2244 aa)
	DwilGK10356	Phosphodiesterase. (1089 aa)

Your Current Organism:

Drosophila willistoni

NCBI taxonomy Id: 7260
Other names: D. willistoni

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
DwilGK10354	DwilGK12879	B4MJA6	B4NJ97	Uncharacterized protein.	Uncharacterized protein.	0.404
DwilGK10354	DwilGK15458	B4MJA6	B4MVA0	Uncharacterized protein.	Uncharacterized protein; Belongs to the protein kinase superfamily.	0.616
DwilGK10354	DwilGK18424	B4MJA6	B4NPP7	Uncharacterized protein.	Uncharacterized protein, isoform A; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.	0.487
DwilGK10356	DwilGK12879	A0A0Q9WZA2	B4NJ97	Phosphodiesterase.	Uncharacterized protein.	0.404
DwilGK10356	DwilGK15458	A0A0Q9WZA2	B4MVA0	Phosphodiesterase.	Uncharacterized protein; Belongs to the protein kinase superfamily.	0.616
DwilGK10356	DwilGK18424	A0A0Q9WZA2	B4NPP7	Phosphodiesterase.	Uncharacterized protein, isoform A; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.	0.946
DwilGK10907	DwilGK14890	A0A0Q9X5M6	B4MU95	Uncharacterized protein, isoform B.	WH2 domain-containing protein.	0.982
DwilGK10907	DwilGK17312	A0A0Q9X5M6	B4NQ65	Uncharacterized protein, isoform B.	Uncharacterized protein.	0.614
DwilGK10907	DwilGK20502	A0A0Q9X5M6	B4N547	Uncharacterized protein, isoform B.	GK20502.	0.614
DwilGK11933	DwilGK12570	B4N4B9	B4N2V2	RING-type domain-containing protein.	RING-type domain-containing protein.	0.966
DwilGK12078	DwilGK14922	B4N8K5	B4MWA1	Uncharacterized protein.	Uncharacterized protein.	0.432
DwilGK12160	DwilGK24804	A0A0Q9X1S6	B4N176	Uncharacterized protein, isoform C.	Uncharacterized protein.	0.482
DwilGK12444	DwilGK17312	B4NGJ8	B4NQ65	Mitogen-activated protein kinase.	Uncharacterized protein.	0.613
DwilGK12444	DwilGK20502	B4NGJ8	B4N547	Mitogen-activated protein kinase.	GK20502.	0.962
DwilGK12444	DwilGK25249	B4NGJ8	B4NEN2	Mitogen-activated protein kinase.	Protein kinase domain-containing protein.	0.996
DwilGK12444	DwilGK25610	B4NGJ8	B4NEA1	Mitogen-activated protein kinase.	Uncharacterized protein.	0.430
DwilGK12444	kay	B4NGJ8	B4NBL5	Mitogen-activated protein kinase.	Transcription factor kayak; Developmentally regulated transcription factor AP-1 binds and recognizes the enhancer DNA sequence: 5'-TGA[CG]TCA-3'. May play a role in the function or determination of a particular subset of cells in the developing embryo. It is able to carry out its function either independently of or in conjunction with Jra (By similarity).	0.989
DwilGK12461	DwilGK12696	B4N4Q2	B4N3F9	Uncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family.	Uncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family.	0.920
DwilGK12461	DwilGK15749	B4N4Q2	B4MRH6	Uncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family.	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	0.885
DwilGK12461	DwilGK19910	B4N4Q2	B4MSF8	Uncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family.	Uncharacterized protein.	0.423