(27 nodes) Stem cell differentiation network (Drosophila willistoni)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	DwilGK24332	Uncharacterized protein. (578 aa)
	DwilGK19792	Tudor domain-containing protein. (226 aa)
	Dwilrho	Rhomboid; Belongs to the peptidase S54 family. (361 aa)
	DwilGK21996	GK21996. (840 aa)
	DwilGK15972	Uncharacterized protein. (886 aa)
	DwilGK14633	Rhomboid domain-containing protein. (201 aa)
	DwilGK14947	Uncharacterized protein. (1551 aa)
	DwilGK15084	Uncharacterized protein. (688 aa)
	DwilGK15086	Uncharacterized protein. (596 aa)
	DwilGK10715	Uncharacterized protein. (200 aa)
	DwilGK10766	Receptor protein-tyrosine kinase. (1386 aa)
	DwilGK20901	Zinc finger FYVE domain-containing protein. (1296 aa)
	DwilGK13480	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (863 aa)
	Dwilsav	Sav. (580 aa)
	DwilGK11836	Fibroblast growth factor receptor. (758 aa)
	DwilGK11542	Uncharacterized protein. (552 aa)
	DwilGK17279	Uncharacterized protein. (2653 aa)
	DwilGK18347	Uncharacterized protein. (512 aa)
	DwilGK13255	Uncharacterized protein. (553 aa)
	DwilGK13318	Uncharacterized protein, isoform B. (2625 aa)
	DwilGK13853	Uncharacterized protein, isoform A. (590 aa)
	DwilGK14502	Homeobox domain-containing protein. (424 aa)
	Dwilwg	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (477 aa)
	DwilGK12696	Uncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family. (423 aa)
	DwilGK12461	Uncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family. (826 aa)
	DwilGK17881	Uncharacterized protein; Belongs to the heparin-binding growth factors family. (647 aa)
	DwilGK18043	Uncharacterized protein. (380 aa)

Your Current Organism:

Drosophila willistoni

NCBI taxonomy Id: 7260
Other names: D. willistoni

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structured XML interaction data, according to the 'PSI-MI' data standard

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a flat-file format describing the coordinates and colors of nodes in the network

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
DwilGK10766	DwilGK11542	B4MJ19	B4N8Y0	Receptor protein-tyrosine kinase.	Uncharacterized protein.	0.483
DwilGK10766	DwilGK13318	B4MJ19	B4NKQ3	Receptor protein-tyrosine kinase.	Uncharacterized protein, isoform B.	0.554
DwilGK10766	DwilGK17279	B4MJ19	B4NQ59	Receptor protein-tyrosine kinase.	Uncharacterized protein.	0.532
DwilGK10766	DwilGK21996	B4MJ19	B4MR44	Receptor protein-tyrosine kinase.	GK21996.	0.467
DwilGK10766	DwilGK24332	B4MJ19	B4MZQ0	Receptor protein-tyrosine kinase.	Uncharacterized protein.	0.420
DwilGK10766	Dwilrho	B4MJ19	B4MLF4	Receptor protein-tyrosine kinase.	Rhomboid; Belongs to the peptidase S54 family.	0.653
DwilGK10766	Dwilwg	B4MJ19	B4MZW4	Receptor protein-tyrosine kinase.	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	0.461
DwilGK11542	DwilGK10766	B4N8Y0	B4MJ19	Uncharacterized protein.	Receptor protein-tyrosine kinase.	0.483
DwilGK11542	DwilGK14502	B4N8Y0	B4NKI5	Uncharacterized protein.	Homeobox domain-containing protein.	0.547
DwilGK11836	DwilGK17881	B4NB61	B4N5Q7	Fibroblast growth factor receptor.	Uncharacterized protein; Belongs to the heparin-binding growth factors family.	0.778
DwilGK12461	DwilGK12696	B4N4Q2	B4N3F9	Uncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family.	Uncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family.	0.920
DwilGK12461	Dwilwg	B4N4Q2	B4MZW4	Uncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family.	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	0.977
DwilGK12696	DwilGK12461	B4N3F9	B4N4Q2	Uncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family.	Uncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family.	0.920
DwilGK12696	Dwilwg	B4N3F9	B4MZW4	Uncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family.	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	0.973
DwilGK13255	DwilGK14502	B4NL23	B4NKI5	Uncharacterized protein.	Homeobox domain-containing protein.	0.760
DwilGK13318	DwilGK10766	B4NKQ3	B4MJ19	Uncharacterized protein, isoform B.	Receptor protein-tyrosine kinase.	0.554
DwilGK13480	DwilGK17279	B4NIU4	B4NQ59	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling.	Uncharacterized protein.	0.992
DwilGK14502	DwilGK11542	B4NKI5	B4N8Y0	Homeobox domain-containing protein.	Uncharacterized protein.	0.547
DwilGK14502	DwilGK13255	B4NKI5	B4NL23	Homeobox domain-containing protein.	Uncharacterized protein.	0.760
DwilGK14502	DwilGK15084	B4NKI5	B4MVI6	Homeobox domain-containing protein.	Uncharacterized protein.	0.574