(18 nodes) Positive regulation of ERK1 and ERK2 cascade network (Drosophila willistoni)

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

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co-expression

protein homology

Your Input:
	DwilGK17655	Uncharacterized protein, isoform B. (996 aa)
	DwilGK23066	Uncharacterized protein; Belongs to the cyclic nucleotide phosphodiesterase family. (960 aa)
	DwilGK13307	Uncharacterized protein; Belongs to the DOCK family. (2024 aa)
	DwilGK12864	Uncharacterized protein. (769 aa)
	DwilGK25150	Uncharacterized protein. (774 aa)
	DwilGK11853	Uncharacterized protein. (988 aa)
	DwilGK18706	Uncharacterized protein. (408 aa)
	DwilGK20561	GK20561. (184 aa)
	DwilGK20531	GK20531. (392 aa)
	DwilGK23859	Receptor protein-tyrosine kinase. (1496 aa)
	DwilGK21890	GK21890. (1591 aa)
	DwilGK19633	SAM domain-containing protein. (105 aa)
	Dwilvn	Vein. (481 aa)
	DwilGK17305	USP domain-containing protein; Belongs to the peptidase C19 family. (1345 aa)
	DwilGK17048	G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family. (626 aa)
	DwilGK10766	Receptor protein-tyrosine kinase. (1386 aa)
	DwilGK10731	Uncharacterized protein; Belongs to the protein kinase superfamily. Tyr protein kinase family. (1759 aa)
	DwilGK10660	Uncharacterized protein. (211 aa)

Your Current Organism:

Drosophila willistoni

NCBI taxonomy Id: 7260
Other names: D. willistoni

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
DwilGK10660	DwilGK10731	B4MIT0	B4MIU7	Uncharacterized protein.	Uncharacterized protein; Belongs to the protein kinase superfamily. Tyr protein kinase family.	0.905
DwilGK10660	DwilGK10766	B4MIT0	B4MJ19	Uncharacterized protein.	Receptor protein-tyrosine kinase.	0.998
DwilGK10660	DwilGK11853	B4MIT0	B4NB95	Uncharacterized protein.	Uncharacterized protein.	0.562
DwilGK10660	DwilGK12864	B4MIT0	B4NJB3	Uncharacterized protein.	Uncharacterized protein.	0.713
DwilGK10660	DwilGK17655	B4MIT0	A0A0Q9X8V1	Uncharacterized protein.	Uncharacterized protein, isoform B.	0.944
DwilGK10660	DwilGK20561	B4MIT0	B4N5E9	Uncharacterized protein.	GK20561.	0.720
DwilGK10660	DwilGK23859	B4MIT0	B4MTK0	Uncharacterized protein.	Receptor protein-tyrosine kinase.	0.893
DwilGK10660	DwilGK25150	B4MIT0	B4NC38	Uncharacterized protein.	Uncharacterized protein.	0.697
DwilGK10660	Dwilvn	B4MIT0	B4MMK9	Uncharacterized protein.	Vein.	0.563
DwilGK10731	DwilGK10660	B4MIU7	B4MIT0	Uncharacterized protein; Belongs to the protein kinase superfamily. Tyr protein kinase family.	Uncharacterized protein.	0.905
DwilGK10731	DwilGK10766	B4MIU7	B4MJ19	Uncharacterized protein; Belongs to the protein kinase superfamily. Tyr protein kinase family.	Receptor protein-tyrosine kinase.	0.719
DwilGK10731	DwilGK20561	B4MIU7	B4N5E9	Uncharacterized protein; Belongs to the protein kinase superfamily. Tyr protein kinase family.	GK20561.	0.404
DwilGK10766	DwilGK10660	B4MJ19	B4MIT0	Receptor protein-tyrosine kinase.	Uncharacterized protein.	0.998
DwilGK10766	DwilGK10731	B4MJ19	B4MIU7	Receptor protein-tyrosine kinase.	Uncharacterized protein; Belongs to the protein kinase superfamily. Tyr protein kinase family.	0.719
DwilGK10766	DwilGK11853	B4MJ19	B4NB95	Receptor protein-tyrosine kinase.	Uncharacterized protein.	0.475
DwilGK10766	DwilGK17655	B4MJ19	A0A0Q9X8V1	Receptor protein-tyrosine kinase.	Uncharacterized protein, isoform B.	0.808
DwilGK10766	DwilGK20531	B4MJ19	B4N596	Receptor protein-tyrosine kinase.	GK20531.	0.686
DwilGK10766	DwilGK20561	B4MJ19	B4N5E9	Receptor protein-tyrosine kinase.	GK20561.	0.550
DwilGK10766	DwilGK23859	B4MJ19	B4MTK0	Receptor protein-tyrosine kinase.	Receptor protein-tyrosine kinase.	0.739
DwilGK10766	DwilGK25150	B4MJ19	B4NC38	Receptor protein-tyrosine kinase.	Uncharacterized protein.	0.667