(152 nodes) PH-like domain superfamily network (Drosophila willistoni)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	DwilGK14196	PH domain-containing protein. (3285 aa)
	DwilGK13206	Uncharacterized protein, isoform B. (1611 aa)
	DwilGK22444	Oxysterol-binding protein; Belongs to the OSBP family. (995 aa)
	DwilGK11146	Uncharacterized protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1901 aa)
	DwilGK16212	DH domain-containing protein. (1395 aa)
	DwilGK16548	Uncharacterized protein. (3131 aa)
	DwilGK17141	Uncharacterized protein. (2007 aa)
	DwilGK10621	Uncharacterized protein. (1148 aa)
	DwilGK23278	RanBD1 domain-containing protein. (536 aa)
	DwilGK17679	Uncharacterized protein. (1176 aa)
	DwilGK14774	DUF1681 domain-containing protein. (243 aa)
	DwilGK14542	Myotubularin phosphatase domain-containing protein. (852 aa)
	DwilGK16883	Uncharacterized protein, isoform A. (644 aa)
	DwilGK16122	Uncharacterized protein. (971 aa)
	DwilGK16096	Uncharacterized protein. (330 aa)
	DwilGK23060	Uncharacterized protein. (762 aa)
	DwilGK23171	PH domain-containing protein. (1493 aa)
	DwilGK23159	Uncharacterized protein. (1141 aa)
	DwilGK24070	FERM domain-containing protein. (574 aa)
	DwilGK18353	Uncharacterized protein, isoform C. (1112 aa)
	DwilGK18383	IRS-type PTB domain-containing protein. (492 aa)
	DwilGK18387	PX domain-containing protein. (529 aa)
	DwilGK13260	Non-specific serine/threonine protein kinase. (674 aa)
	DwilGK13262	Non-specific serine/threonine protein kinase. (531 aa)
	Art4	Histone-arginine methyltransferase CARMER; Methylates (mono- and asymmetric dimethylation) the guanidino nitrogens of arginyl residues in proteins. May methylate histone H3 at 'Arg-17' and activate transcription via chromatin remodeling (By similarity). (533 aa)
	DwilGK13341	Uncharacterized protein, isoform C. (978 aa)
	DwilGK12803	PH domain-containing protein. (685 aa)
	DwilGK13889	FERM domain-containing protein. (780 aa)
	DwilGK12823	Uncharacterized protein. (385 aa)
	DwilGK14415	Uncharacterized protein. (823 aa)
	DwilGK13445	SH3 domain-containing protein. (707 aa)
	DwilGK12864	Uncharacterized protein. (769 aa)
	DwilGK12879	Uncharacterized protein. (2795 aa)
	DwilGK13836	SH2 domain-containing protein. (729 aa)
	DwilGK14310	Uncharacterized protein. (2000 aa)
	DwilGK13517	PH domain-containing protein. (1391 aa)
	DwilGK12974	Uncharacterized protein. (864 aa)
	DwilGK14269	Oxysterol-binding protein; Belongs to the OSBP family. (793 aa)
	DwilGK14191	SMK-1 domain-containing protein. (1029 aa)
	DwilGK13161	Uncharacterized protein. (1373 aa)
	DwilGK22759	FERM domain-containing protein. (1508 aa)
	DwilGK22503	DH domain-containing protein. (1938 aa)
	DwilGK22540	PH domain-containing protein. (336 aa)
	DwilGK25713	Uncharacterized protein, isoform A; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. (1379 aa)
	DwilGK25241	Uncharacterized protein, isoform A; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (876 aa)
	DwilGK25279	Uncharacterized protein. (1074 aa)
	DwilGK25559	Rho-GAP domain-containing protein. (1597 aa)
	DwilGK25538	PH domain-containing protein. (1250 aa)
	DwilGK10179	Uncharacterized protein. (1401 aa)
	DwilGK25059	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1281 aa)
	DwilGK25866	FERM domain-containing protein. (636 aa)
	DwilGK25852	Uncharacterized protein. (1194 aa)
	DwilGK25174	PH domain-containing protein. (1247 aa)
	DwilGK11221	PID domain-containing protein. (858 aa)
	DwilGK11229	Uncharacterized protein. (2783 aa)
	DwilGK11304	Uncharacterized protein. (1575 aa)
	DwilGK11781	Uncharacterized protein. (1598 aa)
	DwilGK10849	RanBD1 domain-containing protein. (459 aa)
	DwilGK11499	Serine/threonine-protein kinase; Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. (842 aa)
	DwilGK10982	Uncharacterized protein. (548 aa)
	DwilGK12067	PID domain-containing protein. (667 aa)
	DwilGK18706	Uncharacterized protein. (408 aa)
	DwilGK21087	ELMO domain-containing protein. (728 aa)
	DwilGK12345	Myotubularin phosphatase domain-containing protein. (623 aa)
	DwilGK18056	Uncharacterized protein. (909 aa)
	DwilGK18055	DH domain-containing protein. (628 aa)
	DwilGK17754	Rab-GAP TBC domain-containing protein. (1225 aa)
	DwilGK17997	Uncharacterized protein. (1471 aa)
	DwilGK17966	WH1 domain-containing protein. (713 aa)
	DwilGK17870	DH domain-containing protein. (675 aa)
	DwilGK17871	DH domain-containing protein. (520 aa)
	DwilGK20379	GK20379. (4389 aa)
	DwilGK20422	GK20422. (1286 aa)
	DwilGK10599	Uncharacterized protein, isoform A. (1124 aa)
	DwilGK11417	PH domain-containing protein. (717 aa)
	DwilGK25417	SEC7 domain-containing protein. (1287 aa)
	DwilGK13336	Uncharacterized protein. (2855 aa)
	DwilGK12724	Uncharacterized protein. (2663 aa)
	DwilGK12674	Uncharacterized protein. (1170 aa)
	DwilGK12654	PH domain-containing protein. (945 aa)
	DwilGK12611	Uncharacterized protein. (3668 aa)
	DwilGK16143	IRS-type PTB domain-containing protein. (635 aa)
	DwilGK16343	Uncharacterized protein. (1100 aa)
	DwilGK24208	Uncharacterized protein, isoform A. (561 aa)
	DwilGK24217	WH1 domain-containing protein. (565 aa)
	DwilGK24390	Uncharacterized protein. (1586 aa)
	DwilGK24617	SH3 domain-containing protein. (758 aa)
	DwilGK24720	Uncharacterized protein; Belongs to the DOCK family. (2278 aa)
	DwilGK18067	Uncharacterized protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (2167 aa)
	DwilGK18264	Uncharacterized protein, isoform C. (991 aa)
	DwilGK18083	PH domain-containing protein. (926 aa)
	DwilGK18200	Uncharacterized protein. (1355 aa)
	DwilGK22092	FACT complex subunit SSRP1; Component of the FACT complex, a general chromatin factor that acts to reorganize nucleosomes. The FACT complex is involved in multiple processes that require DNA as a template such as mRNA elongation, DNA replication and DNA repair. During transcription elongation the FACT complex acts as a histone chaperone that both destabilizes and restores nucleosomal structure. It facilitates the passage of RNA polymerase II and transcription by promoting the dissociation of one histone H2A-H2B dimer from the nucleosome, then subsequently promotes the reestablishment o [...] (730 aa)
	DwilGK21025	Protein kinase domain-containing protein. (886 aa)
	DwilGK13061	Tyrosine-protein phosphatase; Belongs to the protein-tyrosine phosphatase family. Non- receptor class subfamily. (972 aa)
	DwilGK14892	PID domain-containing protein. (224 aa)
	DwilGK15018	Uncharacterized protein. (860 aa)
	DwilGK15068	PH domain-containing protein. (742 aa)
	DwilGK15455	FERM domain-containing protein. (1514 aa)
	DwilGK14704	Uncharacterized protein. (3501 aa)
	DwilGK15399	Myotubularin phosphatase domain-containing protein. (620 aa)
	DwilGK14717	PH domain-containing protein. (314 aa)
	DwilGK15369	Uncharacterized protein. (1306 aa)
	DwilGK23726	Uncharacterized protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (2129 aa)
	DwilGK23891	Uncharacterized protein. (296 aa)
	DwilGK20115	Uncharacterized protein, isoform A. (956 aa)
	DwilGK20104	Uncharacterized protein. (2052 aa)
	DwilGK19980	Uncharacterized protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (3074 aa)
	DwilGK19920	DH domain-containing protein. (1597 aa)
	DwilGK15708	Uncharacterized protein. (1490 aa)
	DwilGK15859	mRNA_decap_C domain-containing protein. (380 aa)
	DwilGK15827	Uncharacterized protein, isoform A. (543 aa)
	DwilGK21377	G protein-coupled receptor kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. GPRK subfamily. (666 aa)
	DwilGK21935	GK21935. (4238 aa)
	DwilGK21918	GK21918. (2615 aa)
	DwilGK21890	GK21890. (1591 aa)
	DwilGK21855	GK21855. (269 aa)
	DwilGK21470	GK21470. (585 aa)
	DwilGK21478	GK21478. (591 aa)
	DwilGK21520	GK21520. (691 aa)
	DwilGK21704	GK21704. (515 aa)
	DwilGK19499	Phospholipase. (1368 aa)
	DwilGK19514	WH1 domain-containing protein. (436 aa)
	DwilGK19539	Uncharacterized protein, isoform C. (1549 aa)
	DwilGK17120	PDZ domain-containing protein. (652 aa)
	DwilGK17117	PID domain-containing protein. (2484 aa)
	DwilGK17104	GLUE N-terminal domain-containing protein. (400 aa)
	DwilGK16607	PID domain-containing protein. (213 aa)
	DwilGK17582	PH domain-containing protein. (721 aa)
	DwilGK16615	Uncharacterized protein. (960 aa)
	DwilGK17568	Uncharacterized protein. (454 aa)
	DwilGK16654	PH domain-containing protein. (1028 aa)
	DwilGK17331	Uncharacterized protein. (528 aa)
	DwilGK17329	PH domain-containing protein. (228 aa)
	DwilGK16864	Uncharacterized protein, isoform C. (2303 aa)
	DwilGK17395	Uncharacterized protein. (2020 aa)
	DwilGK17304	Uncharacterized protein. (2757 aa)
	DwilGK16672	Uncharacterized protein. (656 aa)
	DwilGK16830	Uncharacterized protein, isoform A. (394 aa)
	DwilGK17249	DH domain-containing protein. (1470 aa)
	DwilGK17002	Uncharacterized protein, isoform B. (622 aa)
	DwilGK20669	Uncharacterized protein, isoform C. (1700 aa)
	DwilGK10290	Uncharacterized protein. (3770 aa)
	DwilGK10639	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. (1646 aa)
	DwilGK10723	Uncharacterized protein, isoform B; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (1745 aa)
	DwilGK10720	Uncharacterized protein. (224 aa)
	DwilGK10711	PH domain-containing protein. (595 aa)
	DwilGK10680	PH domain-containing protein. (1242 aa)
	DwilGK17655	Uncharacterized protein, isoform B. (996 aa)
	DwilGK13240	Uncharacterized protein, isoform C. (4245 aa)
	DwilGK16406	Spectrin beta chain; Belongs to the spectrin family. (2309 aa)
	DwilGK27107	PH domain-containing protein. (152 aa)

Your Current Organism:

Drosophila willistoni

NCBI taxonomy Id: 7260
Other names: D. willistoni

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
DwilGK10179	DwilGK16096	B4ND71	B4NPZ8	Uncharacterized protein.	Uncharacterized protein.	0.551
DwilGK10599	DwilGK21470	B4N4H5	B4MQ83	Uncharacterized protein, isoform A.	GK21470.	0.657
DwilGK10599	DwilGK22092	B4N4H5	B4MYD4	Uncharacterized protein, isoform A.	FACT complex subunit SSRP1; Component of the FACT complex, a general chromatin factor that acts to reorganize nucleosomes. The FACT complex is involved in multiple processes that require DNA as a template such as mRNA elongation, DNA replication and DNA repair. During transcription elongation the FACT complex acts as a histone chaperone that both destabilizes and restores nucleosomal structure. It facilitates the passage of RNA polymerase II and transcription by promoting the dissociation of one histone H2A-H2B dimer from the nucleosome, then subsequently promotes the reestablishment o [...]	0.999
DwilGK10639	DwilGK10680	B4MIY0	B4MIP6	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family.	PH domain-containing protein.	0.554
DwilGK10639	DwilGK11781	B4MIY0	B4NAU6	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family.	Uncharacterized protein.	0.611
DwilGK10639	DwilGK15708	B4MIY0	B4MRQ5	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family.	Uncharacterized protein.	0.642
DwilGK10639	DwilGK16864	B4MIY0	B4MM26	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family.	Uncharacterized protein, isoform C.	0.441
DwilGK10639	DwilGK18200	B4MIY0	B4MYQ9	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family.	Uncharacterized protein.	0.450
DwilGK10639	DwilGK18264	B4MIY0	B4MZ99	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family.	Uncharacterized protein, isoform C.	0.503
DwilGK10639	DwilGK21918	B4MIY0	B4MQQ2	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family.	GK21918.	0.584
DwilGK10639	DwilGK21935	B4MIY0	B4MQT4	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family.	GK21935.	0.485
DwilGK10639	DwilGK23171	B4MIY0	B4NML4	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family.	PH domain-containing protein.	0.455
DwilGK10680	DwilGK10639	B4MIP6	B4MIY0	PH domain-containing protein.	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family.	0.554
DwilGK10680	DwilGK18055	B4MIP6	B4N6G8	PH domain-containing protein.	DH domain-containing protein.	0.640
DwilGK10680	DwilGK18056	B4MIP6	B4N6G9	PH domain-containing protein.	Uncharacterized protein.	0.640
DwilGK10680	DwilGK25713	B4MIP6	B4NEV8	PH domain-containing protein.	Uncharacterized protein, isoform A; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family.	0.554
DwilGK10720	DwilGK16122	B4MIS2	B4NPZ2	Uncharacterized protein.	Uncharacterized protein.	0.811
DwilGK10849	DwilGK11229	B4N9Z9	B4NB79	RanBD1 domain-containing protein.	Uncharacterized protein.	0.586
DwilGK10849	DwilGK23278	B4N9Z9	B4NN98	RanBD1 domain-containing protein.	RanBD1 domain-containing protein.	0.649
DwilGK10982	DwilGK18264	B4N8R2	B4MZ99	Uncharacterized protein.	Uncharacterized protein, isoform C.	0.442