(35 nodes) SH2 domain superfamily network (Drosophila willistoni)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	DwilGK25739	Uncharacterized protein. (799 aa)
	DwilGK25059	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1281 aa)
	DwilGK24959	Uncharacterized protein. (512 aa)
	DwilGK21551	Tyrosine-protein kinase. (518 aa)
	DwilGK17605	Tyrosine-protein kinase. (552 aa)
	DwilGK17568	Uncharacterized protein. (454 aa)
	DwilGK17294	SH2 domain-containing protein. (393 aa)
	DwilGK17289	SH2 domain-containing protein. (371 aa)
	DwilGK16887	SH2 domain-containing protein. (460 aa)
	DwilGK10660	Uncharacterized protein. (211 aa)
	DwilGK17655	Uncharacterized protein, isoform B. (996 aa)
	DwilGK27508	Transcription elongation factor spt6; Transcription elongation factor that enhances transcription elongation by RNA polymerase II (RNAPII). Belongs to the SPT6 family. (1879 aa)
	DwilGK26975	SH2 domain-containing protein. (244 aa)
	DwilGK27699	SH2 domain-containing protein. (251 aa)
	DwilGK25620	Uncharacterized protein. (1125 aa)
	DwilGK22722	Signal transducer and activator of transcription. (845 aa)
	DwilGK14117	SH2 domain-containing protein. (210 aa)
	DwilGK13611	Uncharacterized protein. (302 aa)
	DwilGK14320	Tyrosine-protein kinase. (730 aa)
	DwilGK13836	SH2 domain-containing protein. (729 aa)
	DwilGK12864	Uncharacterized protein. (769 aa)
	DwilGK18374	Uncharacterized protein. (528 aa)
	DwilGK23191	Uncharacterized protein. (352 aa)
	DwilGK19766	Uncharacterized protein, isoform C. (1472 aa)
	DwilGK20115	Uncharacterized protein, isoform A. (956 aa)
	DwilGK23856	Tyrosine-protein kinase. (606 aa)
	DwilGK15403	Uncharacterized protein. (971 aa)
	DwilGK20085	Uncharacterized protein. (1688 aa)
	DwilGK18209	Uncharacterized protein. (757 aa)
	DwilGK24636	Uncharacterized protein. (539 aa)
	DwilGK16127	Uncharacterized protein. (1523 aa)
	DwilGK17895	Tyrosine-protein kinase. (929 aa)
	DwilGK18041	Uncharacterized protein. (930 aa)
	DwilGK21875	Transcription elongation factor spt6; Transcription elongation factor that enhances transcription elongation by RNA polymerase II (RNAPII). Belongs to the SPT6 family. (1721 aa)
	DwilGK11727	Tyrosine-protein kinase. (1342 aa)

Your Current Organism:

Drosophila willistoni

NCBI taxonomy Id: 7260
Other names: D. willistoni

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structured XML interaction data, according to the 'PSI-MI' data standard

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a flat-file format describing the coordinates and colors of nodes in the network

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
DwilGK10660	DwilGK12864	B4MIT0	B4NJB3	Uncharacterized protein.	Uncharacterized protein.	0.713
DwilGK10660	DwilGK13611	B4MIT0	B4NHJ7	Uncharacterized protein.	Uncharacterized protein.	0.903
DwilGK10660	DwilGK14117	B4MIT0	B4NGS4	Uncharacterized protein.	SH2 domain-containing protein.	0.957
DwilGK10660	DwilGK14320	B4MIT0	B4NIJ3	Uncharacterized protein.	Tyrosine-protein kinase.	0.680
DwilGK10660	DwilGK17568	B4MIT0	B4MMR9	Uncharacterized protein.	Uncharacterized protein.	0.985
DwilGK10660	DwilGK17605	B4MIT0	B4MMY8	Uncharacterized protein.	Tyrosine-protein kinase.	0.698
DwilGK10660	DwilGK17655	B4MIT0	A0A0Q9X8V1	Uncharacterized protein.	Uncharacterized protein, isoform B.	0.944
DwilGK10660	DwilGK17895	B4MIT0	B4N5N3	Uncharacterized protein.	Tyrosine-protein kinase.	0.482
DwilGK10660	DwilGK18041	B4MIT0	B4N6E0	Uncharacterized protein.	Uncharacterized protein.	0.989
DwilGK10660	DwilGK18374	B4MIT0	B4NLM7	Uncharacterized protein.	Uncharacterized protein.	0.927
DwilGK10660	DwilGK20085	B4MIT0	B4MXF9	Uncharacterized protein.	Uncharacterized protein.	0.795
DwilGK10660	DwilGK21551	B4MIT0	B4MPR7	Uncharacterized protein.	Tyrosine-protein kinase.	0.698
DwilGK10660	DwilGK23856	B4MIT0	B4MTJ7	Uncharacterized protein.	Tyrosine-protein kinase.	0.524
DwilGK10660	DwilGK24636	B4MIT0	B4N0U2	Uncharacterized protein.	Uncharacterized protein.	0.774
DwilGK10660	DwilGK25059	B4MIT0	B4NCL7	Uncharacterized protein.	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades.	0.964
DwilGK10660	DwilGK25739	B4MIT0	B4NBW3	Uncharacterized protein.	Uncharacterized protein.	0.982
DwilGK11727	DwilGK14320	B4NAI9	B4NIJ3	Tyrosine-protein kinase.	Tyrosine-protein kinase.	0.672
DwilGK11727	DwilGK17605	B4NAI9	B4MMY8	Tyrosine-protein kinase.	Tyrosine-protein kinase.	0.600
DwilGK11727	DwilGK17895	B4NAI9	B4N5N3	Tyrosine-protein kinase.	Tyrosine-protein kinase.	0.457
DwilGK11727	DwilGK21551	B4NAI9	B4MPR7	Tyrosine-protein kinase.	Tyrosine-protein kinase.	0.589