(25 nodes) Recycling pathway of L1 network (Drosophila willistoni)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	DwilGK24645	AP-2 complex subunit alpha; Adaptins are components of the adapter complexes which link clathrin to receptors in coated vesicles. (944 aa)
	DwilGK20301	Uncharacterized protein. (470 aa)
	DwilGK20124	Uncharacterized protein. (376 aa)
	DwilGK15913	Uncharacterized protein; Belongs to the actin family. (413 aa)
	DwilGK21751	GK21751. (376 aa)
	EndoA	Endophilin-A; Required presynaptically at the neuromuscular junction. Implicated in synaptic vesicle endocytosis. Belongs to the endophilin family. (366 aa)
	DwilGK17345	AP complex subunit beta. (927 aa)
	DwilGK17241	Clathrin light chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin light chain family. (217 aa)
	DwilGK20814	Uncharacterized protein. (502 aa)
	DwilGK20813	Uncharacterized protein. (497 aa)
	DwilGK23361	Protein kinase domain-containing protein. (163 aa)
	DwilGK16883	Uncharacterized protein, isoform A. (644 aa)
	DwilGK17605	Tyrosine-protein kinase. (552 aa)
	DwilGK23336	Uncharacterized protein. (376 aa)
	DwilGK18345	Uncharacterized protein, isoform C. (1640 aa)
	DwilGK12771	AP complex subunit sigma; Belongs to the adaptor complexes small subunit family. (142 aa)
	DwilGK13943	Uncharacterized protein. (376 aa)
	DwilGK25241	Uncharacterized protein, isoform A; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (876 aa)
	DwilGK25278	Clathrin heavy chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin heavy chain family. (1681 aa)
	DwilGK11317	Uncharacterized protein. (504 aa)
	DwilGK11695	MHD domain-containing protein; Belongs to the adaptor complexes medium subunit family. (437 aa)
	DwilGK11462	Uncharacterized protein. (376 aa)
	DwilGK11479	Uncharacterized protein. (459 aa)
	DwilGK11982	Uncharacterized protein. (503 aa)
	DwilGK10683	Uncharacterized protein. (376 aa)

Your Current Organism:

Drosophila willistoni

NCBI taxonomy Id: 7260
Other names: D. willistoni

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
DwilGK10683	DwilGK11462	B4N4G1	B4N9R8	Uncharacterized protein.	Uncharacterized protein.	0.666
DwilGK10683	DwilGK13943	B4N4G1	B4NKE1	Uncharacterized protein.	Uncharacterized protein.	0.962
DwilGK10683	DwilGK23336	B4N4G1	B4NNK7	Uncharacterized protein.	Uncharacterized protein.	0.940
DwilGK11462	DwilGK10683	B4N9R8	B4N4G1	Uncharacterized protein.	Uncharacterized protein.	0.666
DwilGK11462	DwilGK13943	B4N9R8	B4NKE1	Uncharacterized protein.	Uncharacterized protein.	0.932
DwilGK11462	DwilGK21751	B4N9R8	B4MPR6	Uncharacterized protein.	GK21751.	0.929
DwilGK11462	DwilGK23336	B4N9R8	B4NNK7	Uncharacterized protein.	Uncharacterized protein.	0.934
DwilGK11695	DwilGK12771	B4NAD9	B4NKG7	MHD domain-containing protein; Belongs to the adaptor complexes medium subunit family.	AP complex subunit sigma; Belongs to the adaptor complexes small subunit family.	0.999
DwilGK11695	DwilGK17241	B4NAD9	B4MKV2	MHD domain-containing protein; Belongs to the adaptor complexes medium subunit family.	Clathrin light chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin light chain family.	0.905
DwilGK11695	DwilGK17345	B4NAD9	B4NQ71	MHD domain-containing protein; Belongs to the adaptor complexes medium subunit family.	AP complex subunit beta.	0.998
DwilGK11695	DwilGK24645	B4NAD9	B4N0V9	MHD domain-containing protein; Belongs to the adaptor complexes medium subunit family.	AP-2 complex subunit alpha; Adaptins are components of the adapter complexes which link clathrin to receptors in coated vesicles.	0.999
DwilGK11695	DwilGK25241	B4NAD9	B4NEP3	MHD domain-containing protein; Belongs to the adaptor complexes medium subunit family.	Uncharacterized protein, isoform A; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family.	0.672
DwilGK11695	DwilGK25278	B4NAD9	B4NEJ1	MHD domain-containing protein; Belongs to the adaptor complexes medium subunit family.	Clathrin heavy chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin heavy chain family.	0.935
DwilGK11695	EndoA	B4NAD9	Q8I1A6	MHD domain-containing protein; Belongs to the adaptor complexes medium subunit family.	Endophilin-A; Required presynaptically at the neuromuscular junction. Implicated in synaptic vesicle endocytosis. Belongs to the endophilin family.	0.704
DwilGK12771	DwilGK11695	B4NKG7	B4NAD9	AP complex subunit sigma; Belongs to the adaptor complexes small subunit family.	MHD domain-containing protein; Belongs to the adaptor complexes medium subunit family.	0.999
DwilGK12771	DwilGK17241	B4NKG7	B4MKV2	AP complex subunit sigma; Belongs to the adaptor complexes small subunit family.	Clathrin light chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin light chain family.	0.900
DwilGK12771	DwilGK17345	B4NKG7	B4NQ71	AP complex subunit sigma; Belongs to the adaptor complexes small subunit family.	AP complex subunit beta.	0.994
DwilGK12771	DwilGK24645	B4NKG7	B4N0V9	AP complex subunit sigma; Belongs to the adaptor complexes small subunit family.	AP-2 complex subunit alpha; Adaptins are components of the adapter complexes which link clathrin to receptors in coated vesicles.	0.999
DwilGK12771	DwilGK25241	B4NKG7	B4NEP3	AP complex subunit sigma; Belongs to the adaptor complexes small subunit family.	Uncharacterized protein, isoform A; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family.	0.598
DwilGK12771	DwilGK25278	B4NKG7	B4NEJ1	AP complex subunit sigma; Belongs to the adaptor complexes small subunit family.	Clathrin heavy chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin heavy chain family.	0.926