37 items (Drosophila willistoni) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	DwilGK15981	RING-type domain-containing protein. (112 aa)
	DwilGK10721	Uncharacterized protein. (1075 aa)
	DwilGK20831	RING-type domain-containing protein. (112 aa)
	DwilGK17325	Skp1_POZ domain-containing protein; Belongs to the SKP1 family. (147 aa)
	DwilGK17326	Uncharacterized protein; Belongs to the SKP1 family. (158 aa)
	DwilGK21732	GK21732. (1310 aa)
	DwilGK21971	GK21971; Belongs to the cullin family. (775 aa)
	DwilGK21342	GK21342; Belongs to the SKP1 family. (161 aa)
	DwilGK22018	GK22018; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (1146 aa)
	DwilGK23940	TGF_BETA_2 domain-containing protein. (603 aa)
	DwilGK15458	Uncharacterized protein; Belongs to the protein kinase superfamily. (353 aa)
	DwilGK15298	Uncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family. (1056 aa)
	DwilGK13170	RING-type domain-containing protein. (121 aa)
	DwilGK22225	Homeobox protein engrailed-like. (591 aa)
	DwilGK18163	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (363 aa)
	DwilGK18258	CULLIN_2 domain-containing protein; Belongs to the cullin family. (775 aa)
	iHog	Interference hedgehog; Mediates response to the active Hedgehog (Hh) protein signal in embryos, functioning upstream or at the level of patched (ptc). Belongs to the immunoglobulin superfamily. IHOG family. (881 aa)
	DwilGK24490	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (325 aa)
	DwilGK16427	RING-type domain-containing protein. (108 aa)
	DwilGK16428	Uncharacterized protein; Belongs to the SKP1 family. (162 aa)
	DwilGK20357	GK20357. (123 aa)
	DwilGK24917	Uncharacterized protein. (1020 aa)
	DwilGK25517	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (337 aa)
	DwilGK22839	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (361 aa)
	DwilGK22559	Uncharacterized protein, isoform B; Belongs to the protein kinase superfamily. (435 aa)
	DwilGK22480	Uncharacterized protein. (837 aa)
	DwilGK22764	G protein-coupled receptor kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. GPRK subfamily. (722 aa)
	DwilGK22408	Uncharacterized protein; Belongs to the SKP1 family. (144 aa)
	DwilGK13114	Uncharacterized protein. (354 aa)
	DwilGK13113	Uncharacterized protein, isoform A; Belongs to the protein kinase superfamily. (354 aa)
	DwilGK13666	Uncharacterized protein. (1397 aa)
	DwilGK13559	Suppressor of fused homolog. (477 aa)
	DwilGK13501	Uncharacterized protein. (512 aa)
	hh	Protein hedgehog C-product; Intercellular signal essential for a variety of patterning events during development. Establishes the anterior-posterior axis of the embryonic segments and patterns the larval imaginal disks. Binds to the patched (ptc) receptor, which functions in association with smoothened (smo), to activate the transcription of target genes wingless (wg), decapentaplegic (dpp) and ptc. In the absence of hh, ptc represses the constitutive signaling activity of smo through fused (fu) (By similarity). The hedgehog protein C-product, which mediates the autocatalytic activity, [...] (469 aa)
	DwilGK23055	Uncharacterized protein; Belongs to the SKP1 family. (154 aa)
	DwilGK18099	RING-type domain-containing protein. (160 aa)
	DwilGK10799	Zf-rbx1 domain-containing protein. (112 aa)

Your Current Organism:

Drosophila willistoni

NCBI taxonomy Id: 7260
Other names: D. willistoni

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structured XML interaction data, according to the 'PSI-MI' data standard

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
DwilGK10721	DwilGK13501	B4MIS4	B4NIQ3	Uncharacterized protein.	Uncharacterized protein.	0.426
DwilGK10721	DwilGK21732	B4MIS4	B4MPM7	Uncharacterized protein.	GK21732.	0.978
DwilGK10721	DwilGK23940	B4MIS4	B4MU02	Uncharacterized protein.	TGF_BETA_2 domain-containing protein.	0.681
DwilGK10799	DwilGK13501	B4NRD7	B4NIQ3	Zf-rbx1 domain-containing protein.	Uncharacterized protein.	0.777
DwilGK10799	DwilGK13666	B4NRD7	B4NHI6	Zf-rbx1 domain-containing protein.	Uncharacterized protein.	0.933
DwilGK10799	DwilGK16428	B4NRD7	B4N250	Zf-rbx1 domain-containing protein.	Uncharacterized protein; Belongs to the SKP1 family.	0.887
DwilGK10799	DwilGK17325	B4NRD7	B4MM20	Zf-rbx1 domain-containing protein.	Skp1_POZ domain-containing protein; Belongs to the SKP1 family.	0.887
DwilGK10799	DwilGK17326	B4NRD7	B4MM22	Zf-rbx1 domain-containing protein.	Uncharacterized protein; Belongs to the SKP1 family.	0.887
DwilGK10799	DwilGK18258	B4NRD7	B4MZ92	Zf-rbx1 domain-containing protein.	CULLIN_2 domain-containing protein; Belongs to the cullin family.	0.816
DwilGK10799	DwilGK21342	B4NRD7	B4MR16	Zf-rbx1 domain-containing protein.	GK21342; Belongs to the SKP1 family.	0.887
DwilGK10799	DwilGK21971	B4NRD7	B4MQZ7	Zf-rbx1 domain-containing protein.	GK21971; Belongs to the cullin family.	0.983
DwilGK10799	DwilGK22408	B4NRD7	B4NG64	Zf-rbx1 domain-containing protein.	Uncharacterized protein; Belongs to the SKP1 family.	0.887
DwilGK10799	DwilGK22480	B4NRD7	B4NFQ5	Zf-rbx1 domain-containing protein.	Uncharacterized protein.	0.536
DwilGK10799	DwilGK23055	B4NRD7	B4NMP0	Zf-rbx1 domain-containing protein.	Uncharacterized protein; Belongs to the SKP1 family.	0.887
DwilGK13113	DwilGK13114	B4NGY9	B4NGY8	Uncharacterized protein, isoform A; Belongs to the protein kinase superfamily.	Uncharacterized protein.	0.912
DwilGK13113	DwilGK13559	B4NGY9	B4NI11	Uncharacterized protein, isoform A; Belongs to the protein kinase superfamily.	Suppressor of fused homolog.	0.821
DwilGK13113	DwilGK13666	B4NGY9	B4NHI6	Uncharacterized protein, isoform A; Belongs to the protein kinase superfamily.	Uncharacterized protein.	0.958
DwilGK13113	DwilGK15298	B4NGY9	B4MWJ5	Uncharacterized protein, isoform A; Belongs to the protein kinase superfamily.	Uncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family.	0.954
DwilGK13113	DwilGK15458	B4NGY9	B4MVA0	Uncharacterized protein, isoform A; Belongs to the protein kinase superfamily.	Uncharacterized protein; Belongs to the protein kinase superfamily.	0.913
DwilGK13113	DwilGK18163	B4NGY9	B4MYV6	Uncharacterized protein, isoform A; Belongs to the protein kinase superfamily.	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	0.411