(30 nodes) Phototransduction - fly network (Drosophila willistoni)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	DwilGK23786	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1331 aa)
	DwilGK13605	Uncharacterized protein, isoform B. (531 aa)
	DwilGK23154	Uncharacterized protein, isoform B. (353 aa)
	DwilGK15075	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (72 aa)
	DwilGK15712	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1095 aa)
	DwilGK20857	Uncharacterized protein. (675 aa)
	DwilGK16946	Serine/threonine-protein phosphatase with EF-hands. (748 aa)
	DwilGK16697	Uncharacterized protein. (175 aa)
	DwilGK17474	Arrestin_C domain-containing protein. (401 aa)
	DwilGK21452	GK21452. (158 aa)
	DwilGK21377	G protein-coupled receptor kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. GPRK subfamily. (666 aa)
	DwilGK19414	GK19414; Belongs to the calmodulin family. (148 aa)
	DwilGK21975	GK21975; Belongs to the calmodulin family. (147 aa)
	DwilGK22032	Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (684 aa)
	DwilGK15956	ANK_REP_REGION domain-containing protein; Belongs to the transient receptor (TC 1.A.4) family. (1146 aa)
	DwilGK20124	Uncharacterized protein. (376 aa)
	DwilGK15332	Uncharacterized protein. (2843 aa)
	DwilGK22183	Uncharacterized protein; Belongs to the calmodulin family. (149 aa)
	DwilGK24301	Uncharacterized protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1505 aa)
	DwilGK13039	WD_REPEATS_REGION domain-containing protein. (346 aa)
	DwilGK21094	Uncharacterized protein. (149 aa)
	DwilGK25095	Uncharacterized protein. (152 aa)
	DwilGK10079	Lipase_3 domain-containing protein. (644 aa)
	DwilGK22694	Uncharacterized protein. (149 aa)
	DwilninaE	NinaE. (373 aa)
	DwilGK18987	Uncharacterized protein. (167 aa)
	DwilGK18988	Uncharacterized protein; Belongs to the calmodulin family. (148 aa)
	DwilGK14093	ANK_REP_REGION domain-containing protein; Belongs to the transient receptor (TC 1.A.4) family. (1296 aa)
	DwilGK18470	ANK_REP_REGION domain-containing protein; Belongs to the transient receptor (TC 1.A.4) family. (1153 aa)
	DwilGK15267	Uncharacterized protein. (155 aa)

Your Current Organism:

Drosophila willistoni

NCBI taxonomy Id: 7260
Other names: D. willistoni

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
DwilGK13039	DwilGK14093	B4N3M3	B4NLF0	WD_REPEATS_REGION domain-containing protein.	ANK_REP_REGION domain-containing protein; Belongs to the transient receptor (TC 1.A.4) family.	0.552
DwilGK13039	DwilGK15075	B4N3M3	A0A0Q9X249	WD_REPEATS_REGION domain-containing protein.	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.	0.986
DwilGK13039	DwilGK15712	B4N3M3	A0A0Q9X6K4	WD_REPEATS_REGION domain-containing protein.	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes.	0.917
DwilGK13039	DwilGK15956	B4N3M3	B4MS74	WD_REPEATS_REGION domain-containing protein.	ANK_REP_REGION domain-containing protein; Belongs to the transient receptor (TC 1.A.4) family.	0.659
DwilGK13039	DwilGK17474	B4N3M3	B4MMF8	WD_REPEATS_REGION domain-containing protein.	Arrestin_C domain-containing protein.	0.767
DwilGK13039	DwilGK20857	B4N3M3	B4MJM0	WD_REPEATS_REGION domain-containing protein.	Uncharacterized protein.	0.586
DwilGK13039	DwilGK23154	B4N3M3	A0A0Q9WW81	WD_REPEATS_REGION domain-containing protein.	Uncharacterized protein, isoform B.	0.991
DwilGK13039	DwilGK23786	B4N3M3	A0A0Q9WRM6	WD_REPEATS_REGION domain-containing protein.	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes.	0.940
DwilGK13039	DwilGK24301	B4N3M3	B4MZW1	WD_REPEATS_REGION domain-containing protein.	Uncharacterized protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.	0.449
DwilGK13039	DwilninaE	B4N3M3	B4NGD9	WD_REPEATS_REGION domain-containing protein.	NinaE.	0.975
DwilGK13605	DwilGK15267	A0A0Q9WUI9	B4NPG0	Uncharacterized protein, isoform B.	Uncharacterized protein.	0.465
DwilGK13605	DwilGK15712	A0A0Q9WUI9	A0A0Q9X6K4	Uncharacterized protein, isoform B.	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes.	0.905
DwilGK13605	DwilGK16697	A0A0Q9WUI9	B4ML99	Uncharacterized protein, isoform B.	Uncharacterized protein.	0.767
DwilGK13605	DwilGK17474	A0A0Q9WUI9	B4MMF8	Uncharacterized protein, isoform B.	Arrestin_C domain-containing protein.	0.917
DwilGK13605	DwilGK18987	A0A0Q9WUI9	B4NJB9	Uncharacterized protein, isoform B.	Uncharacterized protein.	0.767
DwilGK13605	DwilGK18988	A0A0Q9WUI9	B4NJC0	Uncharacterized protein, isoform B.	Uncharacterized protein; Belongs to the calmodulin family.	0.767
DwilGK13605	DwilGK19414	A0A0Q9WUI9	B4MR07	Uncharacterized protein, isoform B.	GK19414; Belongs to the calmodulin family.	0.777
DwilGK13605	DwilGK21094	A0A0Q9WUI9	B4N789	Uncharacterized protein, isoform B.	Uncharacterized protein.	0.465
DwilGK13605	DwilGK21452	A0A0Q9WUI9	B4MQB0	Uncharacterized protein, isoform B.	GK21452.	0.767
DwilGK13605	DwilGK21975	A0A0Q9WUI9	B4MR09	Uncharacterized protein, isoform B.	GK21975; Belongs to the calmodulin family.	0.767