(36 nodes) Serine proteases, trypsin family, serine active site, and Carboxypeptidase activation peptide network (Drosophila guanche)

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	DGUA_6G006559	Blast:Platelet binding protein GspB. (319 aa)
	DGUA_6G001584	Blast:Trypsin alpha; Belongs to the peptidase S1 family. (256 aa)
	DGUA_6G001583	Blast:Trypsin alpha; Belongs to the peptidase S1 family. (256 aa)
	DGUA_6G007827	Blast:Carboxypeptidase B. (422 aa)
	DGUA_6G005283	Blast:Chymotrypsin-2; Belongs to the peptidase S1 family. (272 aa)
	DGUA_6G001581	Blast:Trypsin alpha; Belongs to the peptidase S1 family. (272 aa)
	DGUA_6G013726	Blast:Serine proteases 1/2; Belongs to the peptidase S1 family. (276 aa)
	DGUA_6G013581	Metalloendopeptidase. (262 aa)
	DGUA_6G013727	Blast:Serine proteases 1/2; Belongs to the peptidase S1 family. (258 aa)
	DGUA_6G005875	Blast:Serine protease 3; Belongs to the peptidase S1 family. (268 aa)
	DGUA_6G001580	Blast:Trypsin theta; Belongs to the peptidase S1 family. (262 aa)
	DGUA_6G001577	Blast:Trypsin eta. (272 aa)
	DGUA_6G001582	Blast:Trypsin epsilon; Belongs to the peptidase S1 family. (256 aa)
	DGUA_6G014565	Blast:Serine proteases 1/2; Belongs to the peptidase S1 family. (263 aa)
	DGUA_6G003213	Blast:Proprotein convertase subtilisin/kexin type 5. (2982 aa)
	DGUA_6G016233	Blast:Putative serine protease K12H4.7. (448 aa)
	DGUA_6G001579	Blast:Trypsin eta; Belongs to the peptidase S1 family. (262 aa)
	DGUA_6G014983	Blast:Brachyurin; Belongs to the peptidase S1 family. (285 aa)
	DGUA_6G016232	Blast:Putative serine protease K12H4.7. (489 aa)
	DGUA_6G014979	Blast:Serine proteases 1/2; Belongs to the peptidase S1 family. (262 aa)
	DGUA_6G007824	Blast:Carboxypeptidase B. (424 aa)
	DGUA_6G014978	Blast:Serine proteases 1/2; Belongs to the peptidase S1 family. (271 aa)
	DGUA_6G004161	Blast:Zinc carboxypeptidase A 1. (425 aa)
	DGUA_6G010534	Uncharacterized protein. (195 aa)
	DGUA_6G008868	DUF725 domain-containing protein. (217 aa)
	DGUA_6G009913	Blast:Retinoid-inducible serine carboxypeptidase; Belongs to the peptidase S10 family. (446 aa)
	DGUA_6G015674	Aminopeptidase. (972 aa)
	DGUA_6G015673	Aminopeptidase. (944 aa)
	DGUA_6G014976	Blast:Serine proteases 1/2; Belongs to the peptidase S1 family. (281 aa)
	DGUA_6G014975	Blast:Serine proteases 1/2; Belongs to the peptidase S1 family. (273 aa)
	DGUA_6G014566	Blast:Chymotrypsin BI; Belongs to the peptidase S1 family. (333 aa)
	DGUA_6G014977	Blast:Serine proteases 1/2; Belongs to the peptidase S1 family. (272 aa)
	DGUA_6G014984	Blast:Chymotrypsin BI; Belongs to the peptidase S1 family. (316 aa)
	DGUA_6G015672	Blast:Aminopeptidase M1-C. (268 aa)
	DGUA_6G019546	Blast:Trypsin; Belongs to the peptidase S1 family. (270 aa)
	DGUA_6G015951	Blast:Phosphatidylethanolamine-binding protein homolog F40A3.3. (176 aa)

Your Current Organism:

Drosophila guanche

NCBI taxonomy Id: 7266
Other names: D. guanche

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
DGUA_6G001577	DGUA_6G001579	A0A3B0JL90	A0A3B0JSD8	Blast:Trypsin eta.	Blast:Trypsin eta; Belongs to the peptidase S1 family.	0.854
DGUA_6G001577	DGUA_6G001580	A0A3B0JL90	A0A3B0JKL2	Blast:Trypsin eta.	Blast:Trypsin theta; Belongs to the peptidase S1 family.	0.501
DGUA_6G001577	DGUA_6G006559	A0A3B0JL90	A0A3B0J3A6	Blast:Trypsin eta.	Blast:Platelet binding protein GspB.	0.492
DGUA_6G001577	DGUA_6G013581	A0A3B0JL90	A0A3B0JI07	Blast:Trypsin eta.	Metalloendopeptidase.	0.698
DGUA_6G001577	DGUA_6G014979	A0A3B0JL90	A0A3B0JVK4	Blast:Trypsin eta.	Blast:Serine proteases 1/2; Belongs to the peptidase S1 family.	0.524
DGUA_6G001577	DGUA_6G014983	A0A3B0JL90	A0A3B0JSK5	Blast:Trypsin eta.	Blast:Brachyurin; Belongs to the peptidase S1 family.	0.667
DGUA_6G001577	DGUA_6G014984	A0A3B0JL90	A0A3B0KMR4	Blast:Trypsin eta.	Blast:Chymotrypsin BI; Belongs to the peptidase S1 family.	0.665
DGUA_6G001577	DGUA_6G015672	A0A3B0JL90	A0A3B0KRK6	Blast:Trypsin eta.	Blast:Aminopeptidase M1-C.	0.446
DGUA_6G001577	DGUA_6G015674	A0A3B0JL90	A0A3B0K3M7	Blast:Trypsin eta.	Aminopeptidase.	0.446
DGUA_6G001577	DGUA_6G015951	A0A3B0JL90	A0A3B0KVY6	Blast:Trypsin eta.	Blast:Phosphatidylethanolamine-binding protein homolog F40A3.3.	0.407
DGUA_6G001577	DGUA_6G016232	A0A3B0JL90	A0A3B0JTN0	Blast:Trypsin eta.	Blast:Putative serine protease K12H4.7.	0.670
DGUA_6G001577	DGUA_6G016233	A0A3B0JL90	A0A3B0JRZ3	Blast:Trypsin eta.	Blast:Putative serine protease K12H4.7.	0.461
DGUA_6G001577	DGUA_6G019546	A0A3B0JL90	A0A3B0KVN0	Blast:Trypsin eta.	Blast:Trypsin; Belongs to the peptidase S1 family.	0.792
DGUA_6G001579	DGUA_6G001577	A0A3B0JSD8	A0A3B0JL90	Blast:Trypsin eta; Belongs to the peptidase S1 family.	Blast:Trypsin eta.	0.854
DGUA_6G001579	DGUA_6G013581	A0A3B0JSD8	A0A3B0JI07	Blast:Trypsin eta; Belongs to the peptidase S1 family.	Metalloendopeptidase.	0.740
DGUA_6G001579	DGUA_6G014983	A0A3B0JSD8	A0A3B0JSK5	Blast:Trypsin eta; Belongs to the peptidase S1 family.	Blast:Brachyurin; Belongs to the peptidase S1 family.	0.426
DGUA_6G001579	DGUA_6G014984	A0A3B0JSD8	A0A3B0KMR4	Blast:Trypsin eta; Belongs to the peptidase S1 family.	Blast:Chymotrypsin BI; Belongs to the peptidase S1 family.	0.420
DGUA_6G001579	DGUA_6G015672	A0A3B0JSD8	A0A3B0KRK6	Blast:Trypsin eta; Belongs to the peptidase S1 family.	Blast:Aminopeptidase M1-C.	0.531
DGUA_6G001579	DGUA_6G015674	A0A3B0JSD8	A0A3B0K3M7	Blast:Trypsin eta; Belongs to the peptidase S1 family.	Aminopeptidase.	0.531
DGUA_6G001579	DGUA_6G016232	A0A3B0JSD8	A0A3B0JTN0	Blast:Trypsin eta; Belongs to the peptidase S1 family.	Blast:Putative serine protease K12H4.7.	0.553