(32 nodes) Negative regulation of transposition network (Drosophila guanche)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	DGUA_6G009231	Staphylococcal nuclease domain-containing protein; Endonuclease that mediates miRNA decay of both protein-free and AGO2-loaded miRNAs. (927 aa)
	DGUA_6G002351	Uncharacterized protein. (374 aa)
	DGUA_6G000317	Blast:Tudor domain-containing protein 7. (1358 aa)
	DGUA_6G002061	RNA-binding protein 8A; Core component of the splicing-dependent multiprotein exon junction complex (EJC) deposited at splice junctions on mRNAs. (165 aa)
	DGUA_6G014311	Blast:Putative ATP-dependent RNA helicase BoYb. (426 aa)
	DGUA_6G014312	Blast:Putative ATP-dependent RNA helicase BoYb. (114 aa)
	DGUA_6G002577	Blast:Protein mago nashi. (147 aa)
	DGUA_6G017779	Blast:Protein vreteno. (702 aa)
	DGUA_6G000954	Blast:Zinc finger CCCH domain-containing protein 13. (674 aa)
	DGUA_6G006700	Blast:Heat shock protein 83. (717 aa)
	DGUA_6G004859	Blast:Apoptotic chromatin condensation inducer in the nucleus. (833 aa)
	DGUA_6G012647	Blast:Tudor and KH domain-containing protein. (575 aa)
	DGUA_6G004089	Blast:Protein argonaute-3; Belongs to the argonaute family. (871 aa)
	DGUA_6G010501	Blast:Histone H1. (181 aa)
	DGUA_6G009668	Blast:Protein argonaute-2. (992 aa)
	DGUA_6G009441	Blast:Nuclear RNA export factor 2. (853 aa)
	DGUA_6G009852	Blast:Histone acetyltransferase KAT2A. (683 aa)
	DGUA_6G019665	Blast:Putative ATP-dependent RNA helicase BoYb. (1136 aa)
	DGUA_6G013445	Blast:Protein piwi; Belongs to the argonaute family. (848 aa)
	DGUA_6G021262	Blast:Histone H1. (179 aa)
	DGUA_6G013078	Blast:tRNA (Cytosine-5-)-methyltransferase; Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family. (349 aa)
	DGUA_6G020014	Uncharacterized protein. (1349 aa)
	DGUA_6G021353	Blast:Protein argonaute-2. (251 aa)
	DGUA_6G013421	Blast:Protein aubergine; Belongs to the argonaute family. (852 aa)
	DGUA_6G016816	Blast:Probable ATP-dependent RNA helicase spindle-E. (1435 aa)
	DGUA_6G004120	Blast:Putative ATP-dependent RNA helicase SoYb. (1425 aa)
	DGUA_6G016380	Blast:RNA-binding protein with serine-rich domain 1. (441 aa)
	DGUA_6G021359	Blast:Histone H1. (114 aa)
	DGUA_6G019023	Blast:Protein vreteno. (705 aa)
	DGUA_6G021358	Blast:Histone H1. (201 aa)
	DGUA_6G020290	Blast:Protein argonaute-2. (767 aa)
	DGUA_6G021250	Blast:Histone H1. (253 aa)

Your Current Organism:

Drosophila guanche

NCBI taxonomy Id: 7266
Other names: D. guanche

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
DGUA_6G000317	DGUA_6G004089	A0A3B0J1V7	A0A3B0JYU3	Blast:Tudor domain-containing protein 7.	Blast:Protein argonaute-3; Belongs to the argonaute family.	0.452
DGUA_6G000317	DGUA_6G013421	A0A3B0J1V7	A0A3B0KDG5	Blast:Tudor domain-containing protein 7.	Blast:Protein aubergine; Belongs to the argonaute family.	0.452
DGUA_6G000317	DGUA_6G013445	A0A3B0J1V7	A0A3B0K6S6	Blast:Tudor domain-containing protein 7.	Blast:Protein piwi; Belongs to the argonaute family.	0.452
DGUA_6G000317	DGUA_6G016816	A0A3B0J1V7	A0A3B0KGQ8	Blast:Tudor domain-containing protein 7.	Blast:Probable ATP-dependent RNA helicase spindle-E.	0.622
DGUA_6G000954	DGUA_6G009441	A0A3B0JQP1	A0A3B0K1B8	Blast:Zinc finger CCCH domain-containing protein 13.	Blast:Nuclear RNA export factor 2.	0.863
DGUA_6G000954	DGUA_6G013421	A0A3B0JQP1	A0A3B0KDG5	Blast:Zinc finger CCCH domain-containing protein 13.	Blast:Protein aubergine; Belongs to the argonaute family.	0.582
DGUA_6G000954	DGUA_6G013445	A0A3B0JQP1	A0A3B0K6S6	Blast:Zinc finger CCCH domain-containing protein 13.	Blast:Protein piwi; Belongs to the argonaute family.	0.838
DGUA_6G002061	DGUA_6G002577	A0A3B0JGF2	A0A3B0JNG1	RNA-binding protein 8A; Core component of the splicing-dependent multiprotein exon junction complex (EJC) deposited at splice junctions on mRNAs.	Blast:Protein mago nashi.	0.999
DGUA_6G002061	DGUA_6G004120	A0A3B0JGF2	A0A3B0KIN9	RNA-binding protein 8A; Core component of the splicing-dependent multiprotein exon junction complex (EJC) deposited at splice junctions on mRNAs.	Blast:Putative ATP-dependent RNA helicase SoYb.	0.475
DGUA_6G002061	DGUA_6G004859	A0A3B0JGF2	A0A3B0JVZ1	RNA-binding protein 8A; Core component of the splicing-dependent multiprotein exon junction complex (EJC) deposited at splice junctions on mRNAs.	Blast:Apoptotic chromatin condensation inducer in the nucleus.	0.776
DGUA_6G002061	DGUA_6G009441	A0A3B0JGF2	A0A3B0K1B8	RNA-binding protein 8A; Core component of the splicing-dependent multiprotein exon junction complex (EJC) deposited at splice junctions on mRNAs.	Blast:Nuclear RNA export factor 2.	0.622
DGUA_6G002061	DGUA_6G014311	A0A3B0JGF2	A0A3B0JJ46	RNA-binding protein 8A; Core component of the splicing-dependent multiprotein exon junction complex (EJC) deposited at splice junctions on mRNAs.	Blast:Putative ATP-dependent RNA helicase BoYb.	0.475
DGUA_6G002061	DGUA_6G014312	A0A3B0JGF2	A0A3B0JJM3	RNA-binding protein 8A; Core component of the splicing-dependent multiprotein exon junction complex (EJC) deposited at splice junctions on mRNAs.	Blast:Putative ATP-dependent RNA helicase BoYb.	0.475
DGUA_6G002061	DGUA_6G016380	A0A3B0JGF2	A0A3B0KJF4	RNA-binding protein 8A; Core component of the splicing-dependent multiprotein exon junction complex (EJC) deposited at splice junctions on mRNAs.	Blast:RNA-binding protein with serine-rich domain 1.	0.991
DGUA_6G002061	DGUA_6G019665	A0A3B0JGF2	A0A3B0K5K6	RNA-binding protein 8A; Core component of the splicing-dependent multiprotein exon junction complex (EJC) deposited at splice junctions on mRNAs.	Blast:Putative ATP-dependent RNA helicase BoYb.	0.475
DGUA_6G002351	DGUA_6G020014	A0A3B0J1C9	A0A3B0K981	Uncharacterized protein.	Uncharacterized protein.	0.703
DGUA_6G002577	DGUA_6G002061	A0A3B0JNG1	A0A3B0JGF2	Blast:Protein mago nashi.	RNA-binding protein 8A; Core component of the splicing-dependent multiprotein exon junction complex (EJC) deposited at splice junctions on mRNAs.	0.999
DGUA_6G002577	DGUA_6G004120	A0A3B0JNG1	A0A3B0KIN9	Blast:Protein mago nashi.	Blast:Putative ATP-dependent RNA helicase SoYb.	0.463
DGUA_6G002577	DGUA_6G004859	A0A3B0JNG1	A0A3B0JVZ1	Blast:Protein mago nashi.	Blast:Apoptotic chromatin condensation inducer in the nucleus.	0.903
DGUA_6G002577	DGUA_6G014311	A0A3B0JNG1	A0A3B0JJ46	Blast:Protein mago nashi.	Blast:Putative ATP-dependent RNA helicase BoYb.	0.463