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DGUA_6G006660 DGUA_6G006660 DGUA_6G015100 DGUA_6G015100 DGUA_6G015043 DGUA_6G015043 DGUA_6G017819 DGUA_6G017819 DGUA_6G017061 DGUA_6G017061 DGUA_6G000897 DGUA_6G000897 DGUA_6G008103 DGUA_6G008103 DGUA_6G016363 DGUA_6G016363 DGUA_6G016366 DGUA_6G016366 DGUA_6G001862 DGUA_6G001862 DGUA_6G001851 DGUA_6G001851 DGUA_6G002523 DGUA_6G002523 DGUA_6G006177 DGUA_6G006177 DGUA_6G000928 DGUA_6G000928 DGUA_6G003260 DGUA_6G003260 DGUA_6G000931 DGUA_6G000931 DGUA_6G014087 DGUA_6G014087 DGUA_6G012267 DGUA_6G012267 DGUA_6G006180 DGUA_6G006180 DGUA_6G005476 DGUA_6G005476 DGUA_6G000840 DGUA_6G000840 DGUA_6G000694 DGUA_6G000694 DGUA_6G010872 DGUA_6G010872 DGUA_6G010172 DGUA_6G010172 DGUA_6G007544 DGUA_6G007544 DGUA_6G006619 DGUA_6G006619 DGUA_6G010234 DGUA_6G010234 DGUA_6G010173 DGUA_6G010173 DGUA_6G002888 DGUA_6G002888 DGUA_6G002810 DGUA_6G002810 DGUA_6G007393 DGUA_6G007393 DGUA_6G007032 DGUA_6G007032 DGUA_6G000554 DGUA_6G000554 DGUA_6G002949 DGUA_6G002949 DGUA_6G000452 DGUA_6G000452 DGUA_6G000927 DGUA_6G000927 DGUA_6G015775 DGUA_6G015775 DGUA_6G020523 DGUA_6G020523 DGUA_6G019484 DGUA_6G019484 DGUA_6G020085 DGUA_6G020085 DGUA_6G008584 DGUA_6G008584 DGUA_6G014471 DGUA_6G014471 DGUA_6G008849 DGUA_6G008849 DGUA_6G015040 DGUA_6G015040 DGUA_6G018341 DGUA_6G018341 DGUA_6G014775 DGUA_6G014775 DGUA_6G013795 DGUA_6G013795 DGUA_6G017017 DGUA_6G017017 DGUA_6G016304 DGUA_6G016304 DGUA_6G013472 DGUA_6G013472 DGUA_6G016333 DGUA_6G016333 DGUA_6G017688 DGUA_6G017688 DGUA_6G017359 DGUA_6G017359 DGUA_6G019333 DGUA_6G019333 DGUA_6G013473 DGUA_6G013473 DGUA_6G005489 DGUA_6G005489 DGUA_6G018343 DGUA_6G018343 DGUA_6G018322 DGUA_6G018322 DGUA_6G018311 DGUA_6G018311 DGUA_6G019485 DGUA_6G019485 DGUA_6G010975 DGUA_6G010975 DGUA_6G013976 DGUA_6G013976 DGUA_6G010097 DGUA_6G010097 DGUA_6G013474 DGUA_6G013474 DGUA_6G007293 DGUA_6G007293 DGUA_6G009411 DGUA_6G009411 DGUA_6G015042 DGUA_6G015042 DGUA_6G008104 DGUA_6G008104 DGUA_6G008102 DGUA_6G008102 DGUA_6G011794 DGUA_6G011794
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
DGUA_6G006660Malate dehydrogenase. (339 aa)
DGUA_6G015100Blast:2-oxoglutarate dehydrogenase, mitochondrial. (1018 aa)
DGUA_6G015043Uncharacterized protein. (415 aa)
DGUA_6G017819Succinate dehydrogenase [ubiquinone] cytochrome b small subunit; Membrane-anchoring subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q); Belongs to the CybS family. (184 aa)
DGUA_6G017061Citrate synthase; Belongs to the citrate synthase family. (506 aa)
DGUA_6G000897Blast:Probable isocitrate dehydrogenase. (390 aa)
DGUA_6G008103Blast:Ecdysone-induced protein 75B, isoform A. (383 aa)
DGUA_6G016363Mitochondrial pyruvate carrier; Mediates the uptake of pyruvate into mitochondria. Belongs to the mitochondrial pyruvate carrier (MPC) (TC 2.A.105) family. (158 aa)
DGUA_6G016366Mitochondrial pyruvate carrier; Mediates the uptake of pyruvate into mitochondria. Belongs to the mitochondrial pyruvate carrier (MPC) (TC 2.A.105) family. (148 aa)
DGUA_6G001862Blast:L-lactate dehydrogenase. (689 aa)
DGUA_6G001851Blast:L-lactate dehydrogenase; Belongs to the LDH/MDH superfamily. (356 aa)
DGUA_6G002523RING-type domain-containing protein. (619 aa)
DGUA_6G006177Blast:Probable maleylacetoacetate isomerase 1; Belongs to the GST superfamily. (258 aa)
DGUA_6G000928Malic enzyme. (603 aa)
DGUA_6G003260Ubiquinone biosynthesis protein; Lipid-binding protein involved in the biosynthesis of coenzyme Q, also named ubiquinone, an essential lipid-soluble electron transporter for aerobic cellular respiration. (348 aa)
DGUA_6G000931Blast:NADP-dependent malic enzyme. (615 aa)
DGUA_6G014087Mitochondrial pyruvate carrier; Mediates the uptake of pyruvate into mitochondria. Belongs to the mitochondrial pyruvate carrier (MPC) (TC 2.A.105) family. (140 aa)
DGUA_6G012267Blast:L-2-hydroxyglutarate dehydrogenase, mitochondrial. (468 aa)
DGUA_6G006180Blast:Probable maleylacetoacetate isomerase 2; Belongs to the GST superfamily. (225 aa)
DGUA_6G005476Malic enzyme. (633 aa)
DGUA_6G000840Blast:Probable isocitrate dehydrogenase. (422 aa)
DGUA_6G000694Malate dehydrogenase. (350 aa)
DGUA_6G010872Blast:Protein ultraspiracle. (485 aa)
DGUA_6G010172Blast:Fumarate hydratase, mitochondrial. (493 aa)
DGUA_6G007544Succinate--CoA ligase [GDP-forming] subunit beta, mitochondrial; GTP-specific succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. (422 aa)
DGUA_6G006619Blast:Probable fumarate hydratase, mitochondrial. (469 aa)
DGUA_6G010234Citrate synthase; Belongs to the citrate synthase family. (521 aa)
DGUA_6G010173Blast:Fumarate hydratase, mitochondrial. (496 aa)
DGUA_6G002888Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial; Flavoprotein (FP) subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q). (661 aa)
DGUA_6G002810Blast:Probable hydroxyacid-oxoacid transhydrogenase, mitochondrial. (464 aa)
DGUA_6G007393Blast:Hydroxyacylglutathione hydrolase, mitochondrial. (343 aa)
DGUA_6G007032Dihydrolipoyl dehydrogenase. (504 aa)
DGUA_6G000554Blast:Lactoylglutathione lyase. (178 aa)
DGUA_6G002949Protein-serine/threonine kinase. (423 aa)
DGUA_6G000452Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial; Iron-sulfur protein (IP) subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q). (297 aa)
DGUA_6G000927Blast:NADP-dependent malic enzyme, mitochondrial. (598 aa)
DGUA_6G015775Malic enzyme; Belongs to the malic enzymes family. (832 aa)
DGUA_6G020523Isocitrate dehydrogenase [NAD] subunit, mitochondrial. (354 aa)
DGUA_6G019484Pyruvate dehydrogenase E1 component subunit alpha; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (399 aa)
DGUA_6G020085Blast:Pyruvate dehydrogenase phosphatase regulatory subunit, mitochondrial. (941 aa)
DGUA_6G008584Blast:Beta-lactamase-like protein 2 homolog. (292 aa)
DGUA_6G014471Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial; Flavoprotein (FP) subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q). (641 aa)
DGUA_6G008849Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial; Iron-sulfur protein (IP) subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q). (354 aa)
DGUA_6G015040L-lactate dehydrogenase; Belongs to the LDH/MDH superfamily. (332 aa)
DGUA_6G018341Aconitate hydratase, mitochondrial; Belongs to the aconitase/IPM isomerase family. (790 aa)
DGUA_6G014775Succinate--CoA ligase [ADP/GDP-forming] subunit alpha, mitochondrial; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and specificity for either ATP or GTP is provided by different beta subunits. (328 aa)
DGUA_6G013795Blast:Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase. (512 aa)
DGUA_6G017017Succinate--CoA ligase [ADP-forming] subunit beta, mitochondrial; ATP-specific succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of ATP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. (451 aa)
DGUA_6G016304Blast:Dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate. (478 aa)
DGUA_6G013472Blast:Voltage-dependent anion-selective channel. (282 aa)
DGUA_6G016333Blast:Malate dehydrogenase, mitochondrial; Belongs to the LDH/MDH superfamily. (336 aa)
DGUA_6G017688Blast:Isocitrate dehydrogenase. (378 aa)
DGUA_6G017359Mitochondrial pyruvate carrier; Mediates the uptake of pyruvate into mitochondria. Belongs to the mitochondrial pyruvate carrier (MPC) (TC 2.A.105) family. (107 aa)
DGUA_6G019333Succinate--CoA ligase [ADP/GDP-forming] subunit alpha, mitochondrial; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and specificity for either ATP or GTP is provided by different beta subunits. (341 aa)
DGUA_6G013473Blast:Voltage-dependent anion-selective channel. (300 aa)
DGUA_6G005489Pyruvate dehydrogenase E1 component subunit beta; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2. (365 aa)
DGUA_6G018343Blast:Succinate dehydrogenase cytochrome b560 subunit, mitochondrial. (248 aa)
DGUA_6G018322Blast:Succinate dehydrogenase cytochrome b560 subunit, mitochondrial. (152 aa)
DGUA_6G018311Blast:Acylpyruvase FAHD1, mitochondrial. (220 aa)
DGUA_6G019485Pyruvate dehydrogenase E1 component subunit alpha; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (526 aa)
DGUA_6G010975Blast. (471 aa)
DGUA_6G013976Aconitate hydratase, mitochondrial; Belongs to the aconitase/IPM isomerase family. (788 aa)
DGUA_6G010097Blast:D-2-hydroxyglutarate dehydrogenase, mitochondrial. (525 aa)
DGUA_6G013474Blast:Voltage-dependent anion-selective channel. (342 aa)
DGUA_6G007293Blast:2-oxoglutarate dehydrogenase, mitochondrial. (1150 aa)
DGUA_6G009411Blast:Putative methyltransferase NSUN7. (719 aa)
DGUA_6G015042Uncharacterized protein. (459 aa)
DGUA_6G008104Blast:Ecdysone-induced protein 75B, isoforms C/D. (286 aa)
DGUA_6G008102Blast:Ecdysone-induced protein 75B, isoform B. (1487 aa)
DGUA_6G011794Pyruvate dehydrogenase E1 component subunit alpha; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (408 aa)
Your Current Organism:
Drosophila guanche
NCBI taxonomy Id: 7266
Other names: D. guanche
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