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DGUA_6G013795 DGUA_6G013795 DGUA_6G016304 DGUA_6G016304 DGUA_6G005489 DGUA_6G005489 DGUA_6G017017 DGUA_6G017017 DGUA_6G006031 DGUA_6G006031 DGUA_6G019333 DGUA_6G019333 DGUA_6G017688 DGUA_6G017688 DGUA_6G016333 DGUA_6G016333 DGUA_6G020523 DGUA_6G020523 DGUA_6G019484 DGUA_6G019484 DGUA_6G015423 DGUA_6G015423 DGUA_6G015236 DGUA_6G015236 DGUA_6G014471 DGUA_6G014471 DGUA_6G008849 DGUA_6G008849 DGUA_6G015209 DGUA_6G015209 DGUA_6G018341 DGUA_6G018341 DGUA_6G014775 DGUA_6G014775 DGUA_6G014850 DGUA_6G014850 DGUA_6G018343 DGUA_6G018343 DGUA_6G018322 DGUA_6G018322 DGUA_6G019485 DGUA_6G019485 DGUA_6G013976 DGUA_6G013976 DGUA_6G007293 DGUA_6G007293 DGUA_6G009411 DGUA_6G009411 DGUA_6G011794 DGUA_6G011794 DGUA_6G004093 DGUA_6G004093 DGUA_6G006660 DGUA_6G006660 DGUA_6G015100 DGUA_6G015100 DGUA_6G017819 DGUA_6G017819 DGUA_6G017061 DGUA_6G017061 DGUA_6G000897 DGUA_6G000897 DGUA_6G002750 DGUA_6G002750 DGUA_6G002523 DGUA_6G002523 DGUA_6G001245 DGUA_6G001245 DGUA_6G017766 DGUA_6G017766 DGUA_6G013280 DGUA_6G013280 DGUA_6G005897 DGUA_6G005897 DGUA_6G000840 DGUA_6G000840 DGUA_6G000694 DGUA_6G000694 DGUA_6G010172 DGUA_6G010172 DGUA_6G007544 DGUA_6G007544 DGUA_6G006619 DGUA_6G006619 DGUA_6G008030 DGUA_6G008030 DGUA_6G010234 DGUA_6G010234 DGUA_6G010173 DGUA_6G010173 DGUA_6G002888 DGUA_6G002888 DGUA_6G007032 DGUA_6G007032 DGUA_6G006736 DGUA_6G006736 DGUA_6G000452 DGUA_6G000452 DGUA_6G002749 DGUA_6G002749 DGUA_6G002711 DGUA_6G002711 DGUA_6G001687 DGUA_6G001687 DGUA_6G000729 DGUA_6G000729
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
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DGUA_6G013795Blast:Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase. (512 aa)
DGUA_6G016304Blast:Dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate. (478 aa)
DGUA_6G005489Pyruvate dehydrogenase E1 component subunit beta; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2. (365 aa)
DGUA_6G017017Succinate--CoA ligase [ADP-forming] subunit beta, mitochondrial; ATP-specific succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of ATP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. (451 aa)
DGUA_6G006031Kinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (713 aa)
DGUA_6G019333Succinate--CoA ligase [ADP/GDP-forming] subunit alpha, mitochondrial; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and specificity for either ATP or GTP is provided by different beta subunits. (341 aa)
DGUA_6G017688Blast:Isocitrate dehydrogenase. (378 aa)
DGUA_6G016333Blast:Malate dehydrogenase, mitochondrial; Belongs to the LDH/MDH superfamily. (336 aa)
DGUA_6G020523Isocitrate dehydrogenase [NAD] subunit, mitochondrial. (354 aa)
DGUA_6G019484Pyruvate dehydrogenase E1 component subunit alpha; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (399 aa)
DGUA_6G015423Blast:Cytoplasmic aconitate hydratase; Belongs to the aconitase/IPM isomerase family. (900 aa)
DGUA_6G015236Blast:Pre-rRNA-processing protein TSR1 homolog. (812 aa)
DGUA_6G014471Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial; Flavoprotein (FP) subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q). (641 aa)
DGUA_6G008849Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial; Iron-sulfur protein (IP) subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q). (354 aa)
DGUA_6G015209Isocitrate dehydrogenase [NADP]; Belongs to the isocitrate and isopropylmalate dehydrogenases family. (448 aa)
DGUA_6G018341Aconitate hydratase, mitochondrial; Belongs to the aconitase/IPM isomerase family. (790 aa)
DGUA_6G014775Succinate--CoA ligase [ADP/GDP-forming] subunit alpha, mitochondrial; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and specificity for either ATP or GTP is provided by different beta subunits. (328 aa)
DGUA_6G014850Blast:Zinc finger MIZ domain-containing protein 1. (1170 aa)
DGUA_6G018343Blast:Succinate dehydrogenase cytochrome b560 subunit, mitochondrial. (248 aa)
DGUA_6G018322Blast:Succinate dehydrogenase cytochrome b560 subunit, mitochondrial. (152 aa)
DGUA_6G019485Pyruvate dehydrogenase E1 component subunit alpha; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (526 aa)
DGUA_6G013976Aconitate hydratase, mitochondrial; Belongs to the aconitase/IPM isomerase family. (788 aa)
DGUA_6G007293Blast:2-oxoglutarate dehydrogenase, mitochondrial. (1150 aa)
DGUA_6G009411Blast:Putative methyltransferase NSUN7. (719 aa)
DGUA_6G011794Pyruvate dehydrogenase E1 component subunit alpha; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (408 aa)
DGUA_6G004093Blast:ATP-binding cassette sub-family C member Sur. (2208 aa)
DGUA_6G006660Malate dehydrogenase. (339 aa)
DGUA_6G015100Blast:2-oxoglutarate dehydrogenase, mitochondrial. (1018 aa)
DGUA_6G017819Succinate dehydrogenase [ubiquinone] cytochrome b small subunit; Membrane-anchoring subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q); Belongs to the CybS family. (184 aa)
DGUA_6G017061Citrate synthase; Belongs to the citrate synthase family. (506 aa)
DGUA_6G000897Blast:Probable isocitrate dehydrogenase. (390 aa)
DGUA_6G002750Blast:Phosphoenolpyruvate carboxykinase. (647 aa)
DGUA_6G002523RING-type domain-containing protein. (619 aa)
DGUA_6G001245Succinate dehydrogenase assembly factor 2, mitochondrial; Plays an essential role in the assembly of succinate dehydrogenase (SDH), an enzyme complex (also referred to as respiratory complex II) that is a component of both the tricarboxylic acid (TCA) cycle and the mitochondrial electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit of the SDH catalytic dimer. (158 aa)
DGUA_6G017766Blast:Cytoplasmic aconitate hydratase. (789 aa)
DGUA_6G013280Malate dehydrogenase. (337 aa)
DGUA_6G005897Blast:4-hydroxybutyrate coenzyme A transferase. (476 aa)
DGUA_6G000840Blast:Probable isocitrate dehydrogenase. (422 aa)
DGUA_6G000694Malate dehydrogenase. (350 aa)
DGUA_6G010172Blast:Fumarate hydratase, mitochondrial. (493 aa)
DGUA_6G007544Succinate--CoA ligase [GDP-forming] subunit beta, mitochondrial; GTP-specific succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. (422 aa)
DGUA_6G006619Blast:Probable fumarate hydratase, mitochondrial. (469 aa)
DGUA_6G008030Blast:Probable isocitrate dehydrogenase. (750 aa)
DGUA_6G010234Citrate synthase; Belongs to the citrate synthase family. (521 aa)
DGUA_6G010173Blast:Fumarate hydratase, mitochondrial. (496 aa)
DGUA_6G002888Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial; Flavoprotein (FP) subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q). (661 aa)
DGUA_6G007032Dihydrolipoyl dehydrogenase. (504 aa)
DGUA_6G006736Blast:Bardet-Biedl syndrome 1 protein. (605 aa)
DGUA_6G000452Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial; Iron-sulfur protein (IP) subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q). (297 aa)
DGUA_6G002749Blast:Phosphoenolpyruvate carboxykinase. (639 aa)
DGUA_6G002711Pyruvate carboxylase; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second. (1197 aa)
DGUA_6G001687Succinate dehydrogenase assembly factor 2, mitochondrial; Plays an essential role in the assembly of succinate dehydrogenase (SDH), an enzyme complex (also referred to as respiratory complex II) that is a component of both the tricarboxylic acid (TCA) cycle and the mitochondrial electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit of the SDH catalytic dimer. (157 aa)
DGUA_6G000729ATP-citrate synthase; In the C-terminal section; belongs to the succinate/malate CoA ligase alpha subunit family. (1113 aa)
Your Current Organism:
Drosophila guanche
NCBI taxonomy Id: 7266
Other names: D. guanche
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