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DGUA_6G011545 DGUA_6G011545 DGUA_6G001887 DGUA_6G001887 DGUA_6G007032 DGUA_6G007032 DGUA_6G002932 DGUA_6G002932 DGUA_6G001008 DGUA_6G001008 DGUA_6G000101 DGUA_6G000101 DGUA_6G004803 DGUA_6G004803 DGUA_6G004192 DGUA_6G004192 DGUA_6G015040 DGUA_6G015040 DGUA_6G014775 DGUA_6G014775 DGUA_6G016374 DGUA_6G016374 DGUA_6G017017 DGUA_6G017017 DGUA_6G019333 DGUA_6G019333 DGUA_6G016163 DGUA_6G016163 DGUA_6G005389 DGUA_6G005389 DGUA_6G005608 DGUA_6G005608 DGUA_6G010947 DGUA_6G010947 DGUA_6G004064 DGUA_6G004064 DGUA_6G004742 DGUA_6G004742 DGUA_6G015042 DGUA_6G015042 DGUA_6G015255 DGUA_6G015255 DGUA_6G010315 DGUA_6G010315 DGUA_6G017045 DGUA_6G017045 DGUA_6G003958 DGUA_6G003958 DGUA_6G015043 DGUA_6G015043 DGUA_6G014575 DGUA_6G014575 DGUA_6G020047 DGUA_6G020047 DGUA_6G017752 DGUA_6G017752 DGUA_6G001862 DGUA_6G001862 DGUA_6G001851 DGUA_6G001851 DGUA_6G002614 DGUA_6G002614 DGUA_6G018145 DGUA_6G018145 DGUA_6G005661 DGUA_6G005661 DGUA_6G000103 DGUA_6G000103 DGUA_6G012537 DGUA_6G012537 DGUA_6G007544 DGUA_6G007544 DGUA_6G011490 DGUA_6G011490 DGUA_6G010325 DGUA_6G010325
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
DGUA_6G011545Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex. (461 aa)
DGUA_6G001887Blast:Probable enoyl-CoA hydratase, mitochondrial; Belongs to the enoyl-CoA hydratase/isomerase family. (296 aa)
DGUA_6G007032Dihydrolipoyl dehydrogenase. (504 aa)
DGUA_6G002932Blast:Acetyl-CoA carboxylase. (2426 aa)
DGUA_6G0010083-hydroxyisobutyrate dehydrogenase; Belongs to the HIBADH-related family. (324 aa)
DGUA_6G000101Acyl-coenzyme A oxidase; Belongs to the acyl-CoA oxidase family. (675 aa)
DGUA_6G004803Acyl-coenzyme A oxidase; Belongs to the acyl-CoA oxidase family. (725 aa)
DGUA_6G004192Blast:Trifunctional enzyme subunit alpha, mitochondrial; Belongs to the enoyl-CoA hydratase/isomerase family. (787 aa)
DGUA_6G015040L-lactate dehydrogenase; Belongs to the LDH/MDH superfamily. (332 aa)
DGUA_6G014775Succinate--CoA ligase [ADP/GDP-forming] subunit alpha, mitochondrial; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and specificity for either ATP or GTP is provided by different beta subunits. (328 aa)
DGUA_6G0163742-oxoisovalerate dehydrogenase subunit alpha; The branched-chain alpha-keto dehydrogenase complex catalyzes the overall conversion of alpha-keto acids to acyl-CoA and CO(2). It contains multiple copies of three enzymatic components: branched-chain alpha-keto acid decarboxylase (E1), lipoamide acyltransferase (E2) and lipoamide dehydrogenase (E3). (439 aa)
DGUA_6G017017Succinate--CoA ligase [ADP-forming] subunit beta, mitochondrial; ATP-specific succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of ATP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. (451 aa)
DGUA_6G019333Succinate--CoA ligase [ADP/GDP-forming] subunit alpha, mitochondrial; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and specificity for either ATP or GTP is provided by different beta subunits. (341 aa)
DGUA_6G016163Blast:Short-chain specific acyl-CoA dehydrogenase, mitochondrial. (405 aa)
DGUA_6G005389Blast:Probable enoyl-CoA hydratase echA8. (379 aa)
DGUA_6G005608Blast:Probable enoyl-CoA hydratase. (325 aa)
DGUA_6G010947Blast:Acetyl-CoA acetyltransferase, mitochondrial; Belongs to the thiolase-like superfamily. Thiolase family. (412 aa)
DGUA_6G004064Blast:2-oxoisovalerate dehydrogenase subunit beta, mitochondrial. (364 aa)
DGUA_6G004742Blast:Glutaredoxin-like protein C5orf63 homolog. (390 aa)
DGUA_6G015042Uncharacterized protein. (459 aa)
DGUA_6G015255Acetyl-coenzyme A synthetase. (670 aa)
DGUA_6G010315Acyl-coenzyme A oxidase; Belongs to the acyl-CoA oxidase family. (678 aa)
DGUA_6G017045Blast:Short-chain specific acyl-CoA dehydrogenase, mitochondrial. (411 aa)
DGUA_6G003958Acyl-coenzyme A oxidase; Belongs to the acyl-CoA oxidase family. (695 aa)
DGUA_6G015043Uncharacterized protein. (415 aa)
DGUA_6G014575Blast:Acetyl-CoA acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family. (392 aa)
DGUA_6G020047Blast:Probable methylmalonate-semialdehyde dehydrogenase. (520 aa)
DGUA_6G017752Blast:Activating signal cointegrator 1 complex subunit 3. (2203 aa)
DGUA_6G001862Blast:L-lactate dehydrogenase. (689 aa)
DGUA_6G001851Blast:L-lactate dehydrogenase; Belongs to the LDH/MDH superfamily. (356 aa)
DGUA_6G002614Acyl-coenzyme A oxidase; Belongs to the acyl-CoA oxidase family. (669 aa)
DGUA_6G018145Blast:Acyl-CoA synthetase short-chain family member 3, mitochondrial. (675 aa)
DGUA_6G0056613-hydroxyisobutyryl-CoA hydrolase, mitochondrial; Hydrolyzes 3-hydroxyisobutyryl-CoA (HIBYL-CoA), a saline catabolite; Belongs to the enoyl-CoA hydratase/isomerase family. (391 aa)
DGUA_6G000103Acyl-coenzyme A oxidase; Belongs to the acyl-CoA oxidase family. (677 aa)
DGUA_6G012537Blast:Myosin heavy chain, striated muscle. (625 aa)
DGUA_6G007544Succinate--CoA ligase [GDP-forming] subunit beta, mitochondrial; GTP-specific succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. (422 aa)
DGUA_6G011490Blast:Polyamine-modulated factor 1-binding protein 1. (484 aa)
DGUA_6G010325Blast:Histone-lysine N-methyltransferase setd3. (579 aa)
Your Current Organism:
Drosophila guanche
NCBI taxonomy Id: 7266
Other names: D. guanche
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