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penA penA mrdB_2 mrdB_2 mrdB_1 mrdB_1 mltB_1 mltB_1 rlpA-2 rlpA-2 mpl mpl ftsB ftsB ftsZ ftsZ ftsA ftsA ftsQ ftsQ murC murC murG murG ftsW ftsW murD murD mraY mraY murF murF murE murE ftsI ftsI ftsL ftsL mraW mraW mraZ mraZ
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
penAUnannotated protein; Catalyzes cross-linking of the peptidoglycan cell wall. Belongs to the transpeptidase family. MrdA subfamily. (641 aa)
mrdB_2Unannotated protein; Peptidoglycan polymerase that is essential for cell wall elongation; Belongs to the SEDS family. MrdB/RodA subfamily. (367 aa)
mrdB_1Unannotated protein. (45 aa)
mltB_1Unannotated protein. (326 aa)
rlpA-2Unannotated protein; Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides. (311 aa)
mplUnannotated protein; Reutilizes the intact tripeptide L-alanyl-gamma-D-glutamyl- meso-diaminopimelate by linking it to UDP-N-acetylmuramate. Belongs to the MurCDEF family. Mpl subfamily. (454 aa)
ftsBUnannotated protein; Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. (105 aa)
ftsZUnannotated protein; Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity. (383 aa)
ftsAUnannotated protein; Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring. Belongs to the FtsA/MreB family. (419 aa)
ftsQUnannotated protein; Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly. (250 aa)
murCUnannotated protein; Cell wall formation; Belongs to the MurCDEF family. (484 aa)
murGUnannotated protein; Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II); Belongs to the glycosyltransferase 28 family. MurG subfamily. (355 aa)
ftsWUnannotated protein; Peptidoglycan polymerase that is essential for cell division. Belongs to the SEDS family. FtsW subfamily. (394 aa)
murDUnannotated protein; Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA). Belongs to the MurCDEF family. (427 aa)
mraYUnannotated protein; First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan; Belongs to the glycosyltransferase 4 family. MraY subfamily. (360 aa)
murFUnannotated protein; Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein; Belongs to the MurCDEF family. MurF subfamily. (451 aa)
murEUnannotated protein; Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan. Belongs to the MurCDEF family. MurE subfamily. (494 aa)
ftsIUnannotated protein; Catalyzes cross-linking of the peptidoglycan cell wall at the division septum; Belongs to the transpeptidase family. FtsI subfamily. (584 aa)
ftsLUnannotated protein; Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. (104 aa)
mraWUnannotated protein; Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA. (312 aa)
mraZUnannotated protein; Belongs to the MraZ family. (177 aa)
Your Current Organism:
Aeromonas encheleia
NCBI taxonomy Id: 73010
Other names: A. encheleia, ATCC 51929, Aeromonas eucrenophila subgroup II, Aeromonas sp. DSM 11577, Aeromonas sp. HG11, CECT 4342, CIP 104608, DSM 11577, LMG 16330, LMG:16330, NCTC 12917, strain S181, ten Aeromonas encheleia-like isolates
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