STRINGSTRING
D0Z67_12610 D0Z67_12610 aepY aepY D0Z67_11915 D0Z67_11915 sdhC sdhC D0Z67_18000 D0Z67_18000 D0Z67_17995 D0Z67_17995 D0Z67_17990 D0Z67_17990 mdh mdh sucD sucD sucC sucC D0Z67_17600 D0Z67_17600 D0Z67_17130 D0Z67_17130 fumC fumC D0Z67_18745 D0Z67_18745 ackA ackA D0Z67_20245 D0Z67_20245 D0Z67_25740 D0Z67_25740 D0Z67_25610 D0Z67_25610 acnA acnA D0Z67_02870 D0Z67_02870 D0Z67_03130 D0Z67_03130 D0Z67_26265 D0Z67_26265 GCA_000725795_04080 GCA_000725795_04080 mmsA mmsA D0Z67_10105 D0Z67_10105 D0Z67_23405 D0Z67_23405 D0Z67_23485 D0Z67_23485 D0Z67_23630 D0Z67_23630 D0Z67_10865 D0Z67_10865 acs acs D0Z67_16060 D0Z67_16060 D0Z67_16965 D0Z67_16965 D0Z67_16960 D0Z67_16960 D0Z67_22260 D0Z67_22260 D0Z67_22220 D0Z67_22220 D0Z67_22215 D0Z67_22215 gabT gabT D0Z67_21390 D0Z67_21390
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
D0Z67_12610Unannotated protein; Belongs to the citrate synthase family. (366 aa)
aepYUnannotated protein. (376 aa)
D0Z67_11915Unannotated protein. (298 aa)
sdhCUnannotated protein. (126 aa)
D0Z67_18000Unannotated protein. (157 aa)
D0Z67_17995Unannotated protein. (584 aa)
D0Z67_17990Unannotated protein; Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family. (253 aa)
mdhUnannotated protein; Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily. MDH type 2 family. (329 aa)
sucDUnannotated protein; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. (294 aa)
sucCUnannotated protein; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. (394 aa)
D0Z67_17600Unannotated protein; Belongs to the aldehyde dehydrogenase family. (537 aa)
D0Z67_17130Unannotated protein. (408 aa)
fumCUnannotated protein; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily. (462 aa)
D0Z67_18745Unannotated protein; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family. (595 aa)
ackAUnannotated protein; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family. (402 aa)
D0Z67_20245Unannotated protein; Involved in acetate metabolism. In the N-terminal section; belongs to the CobB/CobQ family. (696 aa)
D0Z67_25740Unannotated protein; Belongs to the monomeric-type IDH family. (739 aa)
D0Z67_25610Unannotated protein; Belongs to the aldehyde dehydrogenase family. (440 aa)
acnAUnannotated protein; Catalyzes the isomerization of citrate to isocitrate via cis- aconitate. (905 aa)
D0Z67_02870Unannotated protein. (457 aa)
D0Z67_03130Unannotated protein. (461 aa)
D0Z67_26265Unannotated protein. (648 aa)
GCA_000725795_04080Unannotated protein. (367 aa)
mmsAUnannotated protein. (500 aa)
D0Z67_10105Unannotated protein; Belongs to the citrate synthase family. (433 aa)
D0Z67_23405Unannotated protein; Belongs to the TPP enzyme family. (580 aa)
D0Z67_23485Unannotated protein. (557 aa)
D0Z67_23630Unannotated protein; Belongs to the malate synthase family. (540 aa)
D0Z67_10865Unannotated protein. (474 aa)
acsUnannotated protein; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family. (652 aa)
D0Z67_16060Unannotated protein; Belongs to the aldehyde dehydrogenase family. (486 aa)
D0Z67_16965Unannotated protein. (642 aa)
D0Z67_16960Unannotated protein. (352 aa)
D0Z67_22260Unannotated protein. (933 aa)
D0Z67_22220Unannotated protein; Belongs to the citrate synthase family. (394 aa)
D0Z67_22215Unannotated protein. (422 aa)
gabTUnannotated protein; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (444 aa)
D0Z67_21390Unannotated protein. (481 aa)
Your Current Organism:
Streptomyces seoulensis
NCBI taxonomy Id: 73044
Other names: CIP 105312, IFO 16255, IFO 16668, IMSNU 21266, JCM 10116, NBRC 16255, NBRC 16668, S. seoulensis, Streptomyces sp. USC028, Streptomyces sp. USC046, strain IMSNU-1
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