STRINGSTRING
D0Z67_14845 D0Z67_14845 D0Z67_14350 D0Z67_14350 D0Z67_05025 D0Z67_05025 pcrA pcrA D0Z67_19330 D0Z67_19330 D0Z67_19335 D0Z67_19335 D0Z67_19355 D0Z67_19355 D0Z67_20335 D0Z67_20335 D0Z67_25395 D0Z67_25395 D0Z67_03455 D0Z67_03455 sbcD sbcD dinB dinB topA topA polA polA recA recA recQ recQ lexA lexA D0Z67_22110 D0Z67_22110
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
D0Z67_14845Unannotated protein. (485 aa)
D0Z67_14350Unannotated protein. (357 aa)
D0Z67_05025Unannotated protein. (301 aa)
pcrAUnannotated protein. (826 aa)
D0Z67_19330Unannotated protein; Belongs to the helicase family. UvrD subfamily. (1115 aa)
D0Z67_19335Unannotated protein; Belongs to the helicase family. UvrD subfamily. (1137 aa)
D0Z67_19355Unannotated protein. (722 aa)
D0Z67_20335Unannotated protein. (468 aa)
D0Z67_25395Unannotated protein. (567 aa)
D0Z67_03455Unannotated protein. (997 aa)
sbcDUnannotated protein; SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'->5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity; Belongs to the SbcD family. (387 aa)
dinBUnannotated protein; Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII. (466 aa)
topAUnannotated protein; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...] (943 aa)
polAUnannotated protein; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. (888 aa)
recAUnannotated protein; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family. (373 aa)
recQUnannotated protein. (664 aa)
lexAUnannotated protein; Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair. (258 aa)
D0Z67_22110Unannotated protein. (720 aa)
Your Current Organism:
Streptomyces seoulensis
NCBI taxonomy Id: 73044
Other names: CIP 105312, IFO 16255, IFO 16668, IMSNU 21266, JCM 10116, NBRC 16255, NBRC 16668, S. seoulensis, Streptomyces sp. USC028, Streptomyces sp. USC046, strain IMSNU-1
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