STRINGSTRING
D0Z67_23355 D0Z67_23355 lipA lipA nadA nadA D0Z67_05475 D0Z67_05475 D0Z67_12435 D0Z67_12435 whiB whiB GCA_000725795_02271 GCA_000725795_02271 whiB-2 whiB-2 nuoI nuoI nuoB nuoB D0Z67_18745 D0Z67_18745 whiB-3 whiB-3 ispH ispH D0Z67_19080 D0Z67_19080 whiB-4 whiB-4 whiB-5 whiB-5 D0Z67_25830 D0Z67_25830 GCA_000725795_03343 GCA_000725795_03343 ispG ispG acnA acnA D0Z67_20485 D0Z67_20485 leuC leuC D0Z67_02980 D0Z67_02980 bioB bioB moaA-2 moaA-2 D0Z67_23300 D0Z67_23300 D0Z67_24825 D0Z67_24825 rlmN rlmN D0Z67_24085 D0Z67_24085 D0Z67_09290 D0Z67_09290 whiB-7 whiB-7 ispG-2 ispG-2 D0Z67_22395 D0Z67_22395 mqnE mqnE mqnC mqnC nuoB-2 nuoB-2 nuoF nuoF D0Z67_16820 D0Z67_16820 nuoI-2 nuoI-2 miaB miaB rimO rimO D0Z67_29365 D0Z67_29365 D0Z67_06835 D0Z67_06835 D0Z67_06765 D0Z67_06765 D0Z67_16315 D0Z67_16315 nth nth whiB-6 whiB-6 D0Z67_23310 D0Z67_23310 thiC thiC D0Z67_13975 D0Z67_13975 purF purF moaA moaA D0Z67_28355 D0Z67_28355 D0Z67_28385 D0Z67_28385 D0Z67_28440 D0Z67_28440 D0Z67_28700 D0Z67_28700 D0Z67_09205 D0Z67_09205
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
D0Z67_23355Unannotated protein. (439 aa)
lipAUnannotated protein; Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives. (321 aa)
nadAUnannotated protein; Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate. (394 aa)
D0Z67_05475Unannotated protein; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. (752 aa)
D0Z67_12435Unannotated protein. (846 aa)
whiBUnannotated protein; Acts as a transcriptional regulator. Probably redox- responsive. The apo- but not holo-form probably binds DNA. (87 aa)
GCA_000725795_02271Unannotated protein. (238 aa)
whiB-2Unannotated protein; Acts as a transcriptional regulator. Probably redox- responsive. The apo- but not holo-form probably binds DNA. (107 aa)
nuoIUnannotated protein; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. (189 aa)
nuoBUnannotated protein; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. (201 aa)
D0Z67_18745Unannotated protein; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family. (595 aa)
whiB-3Unannotated protein; Acts as a transcriptional regulator. Probably redox- responsive. The apo- but not holo-form probably binds DNA. (121 aa)
ispHUnannotated protein; Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis. Belongs to the IspH family. (338 aa)
D0Z67_19080Unannotated protein; Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions. (106 aa)
whiB-4Unannotated protein; Acts as a transcriptional regulator. Probably redox- responsive. The apo- but not holo-form probably binds DNA. (96 aa)
whiB-5Unannotated protein; Acts as a transcriptional regulator. Probably redox- responsive. The apo- but not holo-form probably binds DNA. (85 aa)
D0Z67_25830Unannotated protein; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. (776 aa)
GCA_000725795_03343Unannotated protein. (36 aa)
ispGUnannotated protein; Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME- 2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate. Belongs to the IspG family. (116 aa)
acnAUnannotated protein; Catalyzes the isomerization of citrate to isocitrate via cis- aconitate. (905 aa)
D0Z67_20485Unannotated protein; Belongs to the iron-sulfur dependent L-serine dehydratase family. (455 aa)
leuCUnannotated protein; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. (475 aa)
D0Z67_02980Unannotated protein. (444 aa)
bioBUnannotated protein; Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism; Belongs to the radical SAM superfamily. Biotin synthase family. (396 aa)
moaA-2Unannotated protein; Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate. (329 aa)
D0Z67_23300Unannotated protein; Reduction of activated sulfate into sulfite. Belongs to the PAPS reductase family. CysH subfamily. (236 aa)
D0Z67_24825Unannotated protein. (213 aa)
rlmNUnannotated protein; Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs; Belongs to the radical SAM superfamily. RlmN family. (368 aa)
D0Z67_24085Unannotated protein. (348 aa)
D0Z67_09290Unannotated protein. (536 aa)
whiB-7Unannotated protein; Acts as a transcriptional regulator. Probably redox- responsive. The apo- but not holo-form probably binds DNA. (81 aa)
ispG-2Unannotated protein; Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME- 2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate. Belongs to the IspG family. (148 aa)
D0Z67_22395Unannotated protein; Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family. (442 aa)
mqnEUnannotated protein; Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3-[(1-carboxyvinyl)oxy]benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate. (387 aa)
mqnCUnannotated protein; Radical SAM enzyme that catalyzes the cyclization of dehypoxanthine futalosine (DHFL) into cyclic dehypoxanthine futalosine (CDHFL), a step in the biosynthesis of menaquinone (MK, vitamin K2). (404 aa)
nuoB-2Unannotated protein; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. (184 aa)
nuoFUnannotated protein; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Belongs to the complex I 51 kDa subunit family. (449 aa)
D0Z67_16820Unannotated protein; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. Belongs to the complex I 75 kDa subunit family. (834 aa)
nuoI-2Unannotated protein; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. (209 aa)
miaBUnannotated protein; Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6- (dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine. (498 aa)
rimOUnannotated protein; Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12; Belongs to the methylthiotransferase family. RimO subfamily. (490 aa)
D0Z67_29365Unannotated protein. (308 aa)
D0Z67_06835Unannotated protein; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. (766 aa)
D0Z67_06765Unannotated protein. (232 aa)
D0Z67_16315Unannotated protein. (291 aa)
nthUnannotated protein; DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'- phosphate. (285 aa)
whiB-6Unannotated protein; Acts as a transcriptional regulator. Probably redox- responsive. The apo- but not holo-form probably binds DNA. (112 aa)
D0Z67_23310Unannotated protein; Belongs to the nitrite and sulfite reductase 4Fe-4S domain family. (565 aa)
thiCUnannotated protein; Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction. Belongs to the ThiC family. (601 aa)
D0Z67_13975Unannotated protein. (199 aa)
purFUnannotated protein; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine. (509 aa)
moaAUnannotated protein; Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate. (343 aa)
D0Z67_28355Unannotated protein; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. (766 aa)
D0Z67_28385Unannotated protein; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. (765 aa)
D0Z67_28440Unannotated protein; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. (767 aa)
D0Z67_28700Unannotated protein. (363 aa)
D0Z67_09205Unannotated protein; Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine. Belongs to the anaerobic coproporphyrinogen-III oxidase family. (410 aa)
Your Current Organism:
Streptomyces seoulensis
NCBI taxonomy Id: 73044
Other names: CIP 105312, IFO 16255, IFO 16668, IMSNU 21266, JCM 10116, NBRC 16255, NBRC 16668, S. seoulensis, Streptomyces sp. USC028, Streptomyces sp. USC046, strain IMSNU-1
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