STRINGSTRING
D0Z67_15450 D0Z67_15450 D0Z67_15350 D0Z67_15350 D0Z67_13800 D0Z67_13800 D0Z67_27840 D0Z67_27840 D0Z67_27910 D0Z67_27910 D0Z67_28355 D0Z67_28355 D0Z67_28385 D0Z67_28385 D0Z67_28440 D0Z67_28440 D0Z67_28640 D0Z67_28640 D0Z67_28705 D0Z67_28705 pfp pfp D0Z67_05475 D0Z67_05475 D0Z67_05470 D0Z67_05470 D0Z67_05350 D0Z67_05350 D0Z67_05265 D0Z67_05265 D0Z67_04965 D0Z67_04965 gpmA gpmA D0Z67_12880 D0Z67_12880 serC serC D0Z67_12495 D0Z67_12495 D0Z67_12435 D0Z67_12435 D0Z67_12185 D0Z67_12185 ppc ppc eno eno fbiB fbiB fbiA fbiA D0Z67_02220 D0Z67_02220 D0Z67_01170 D0Z67_01170 GCA_000725795_02271 GCA_000725795_02271 glyA glyA mdh mdh D0Z67_17720 D0Z67_17720 glpX glpX glyA-2 glyA-2 ackA ackA D0Z67_20245 D0Z67_20245 pfkA pfkA D0Z67_25830 D0Z67_25830 glyA-3 glyA-3 D0Z67_20685 D0Z67_20685 cofC cofC D0Z67_02880 D0Z67_02880 D0Z67_02900 D0Z67_02900 D0Z67_03090 D0Z67_03090 pfkA-2 pfkA-2 serB serB D0Z67_26910 D0Z67_26910 D0Z67_10075 D0Z67_10075 D0Z67_23485 D0Z67_23485 acs acs D0Z67_15915 D0Z67_15915 yvcK yvcK D0Z67_06835 D0Z67_06835 D0Z67_22065 D0Z67_22065 D0Z67_09310 D0Z67_09310
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
D0Z67_15450Unannotated protein; Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis; Belongs to the class II fructose-bisphosphate aldolase family. (340 aa)
D0Z67_15350Unannotated protein. (760 aa)
D0Z67_13800Unannotated protein. (68 aa)
D0Z67_27840Unannotated protein. (362 aa)
D0Z67_27910Unannotated protein. (313 aa)
D0Z67_28355Unannotated protein; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. (766 aa)
D0Z67_28385Unannotated protein; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. (765 aa)
D0Z67_28440Unannotated protein; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. (767 aa)
D0Z67_28640Unannotated protein. (195 aa)
D0Z67_28705Unannotated protein. (488 aa)
pfpUnannotated protein; Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP- PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions. (342 aa)
D0Z67_05475Unannotated protein; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. (752 aa)
D0Z67_05470Unannotated protein. (360 aa)
D0Z67_05350Unannotated protein. (208 aa)
D0Z67_05265Unannotated protein. (228 aa)
D0Z67_04965Unannotated protein. (413 aa)
gpmAUnannotated protein; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate. (253 aa)
D0Z67_12880Unannotated protein. (301 aa)
serCUnannotated protein; Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine; Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily. (372 aa)
D0Z67_12495Unannotated protein. (378 aa)
D0Z67_12435Unannotated protein. (846 aa)
D0Z67_12185Unannotated protein. (371 aa)
ppcUnannotated protein; Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle; Belongs to the PEPCase type 1 family. (914 aa)
enoUnannotated protein; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family. (426 aa)
fbiBUnannotated protein; Bifunctional enzyme that catalyzes the GTP-dependent successive addition of two or more gamma-linked L-glutamates to the L- lactyl phosphodiester of 7,8-didemethyl-8-hydroxy-5-deazariboflavin (F420-0) to form polyglutamated F420 derivatives, and the FMNH2- dependent reduction of dehydro-F420-0 to form F420-0. (433 aa)
fbiAUnannotated protein; Catalyzes the transfer of the phosphoenolpyruvate moiety from enoylpyruvoyl-2-diphospho-5'-guanosine (EPPG) to 7,8-didemethyl-8- hydroxy-5-deazariboflavin (FO) with the formation of dehydro coenzyme F420-0 and GMP. (319 aa)
D0Z67_02220Unannotated protein. (286 aa)
D0Z67_01170Unannotated protein. (670 aa)
GCA_000725795_02271Unannotated protein. (238 aa)
glyAUnannotated protein; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. (485 aa)
mdhUnannotated protein; Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily. MDH type 2 family. (329 aa)
D0Z67_17720Unannotated protein. (392 aa)
glpXUnannotated protein. (343 aa)
glyA-2Unannotated protein; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. (412 aa)
ackAUnannotated protein; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family. (402 aa)
D0Z67_20245Unannotated protein; Involved in acetate metabolism. In the N-terminal section; belongs to the CobB/CobQ family. (696 aa)
pfkAUnannotated protein; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis; Belongs to the phosphofructokinase type A (PFKA) family. Mixed-substrate PFK group III subfamily. (341 aa)
D0Z67_25830Unannotated protein; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. (776 aa)
glyA-3Unannotated protein; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. (422 aa)
D0Z67_20685Unannotated protein; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (533 aa)
cofCUnannotated protein; Guanylyltransferase that catalyzes the activation of phosphoenolpyruvate (PEP) as enolpyruvoyl-2-diphospho-5'-guanosine, via the condensation of PEP with GTP. It is involved in the biosynthesis of coenzyme F420, a hydride carrier cofactor. (216 aa)
D0Z67_02880Unannotated protein. (384 aa)
D0Z67_02900Unannotated protein. (71 aa)
D0Z67_03090Unannotated protein. (120 aa)
pfkA-2Unannotated protein; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis; Belongs to the phosphofructokinase type A (PFKA) family. Mixed-substrate PFK group III subfamily. (341 aa)
serBUnannotated protein. (407 aa)
D0Z67_26910Unannotated protein; Belongs to the glutamate synthase family. (527 aa)
D0Z67_10075Unannotated protein. (315 aa)
D0Z67_23485Unannotated protein. (557 aa)
acsUnannotated protein; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family. (652 aa)
D0Z67_15915Unannotated protein. (276 aa)
yvcKUnannotated protein; Required for morphogenesis under gluconeogenic growth conditions; Belongs to the gluconeogenesis factor family. (363 aa)
D0Z67_06835Unannotated protein; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. (766 aa)
D0Z67_22065Unannotated protein; Belongs to the phosphoglycerate mutase family. (219 aa)
D0Z67_09310Unannotated protein; Belongs to the phosphoglycerate mutase family. (222 aa)
Your Current Organism:
Streptomyces seoulensis
NCBI taxonomy Id: 73044
Other names: CIP 105312, IFO 16255, IFO 16668, IMSNU 21266, JCM 10116, NBRC 16255, NBRC 16668, S. seoulensis, Streptomyces sp. USC028, Streptomyces sp. USC046, strain IMSNU-1
Server load: low (36%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.