(46 nodes) Cytoplasmic vesicle membrane network (Plasmodium yoelii)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	PY02704	Arabinogalactan protein. (265 aa)
	PY07558	Developmental protein DG1118. (128 aa)
	PY06693	Uncharacterized protein. (116 aa)
	PY06523	Clathrin coat assembly protein ap50; Belongs to the adaptor complexes medium subunit family. (601 aa)
	PY05987	Coatomer beta' subunit. (816 aa)
	PY05856	Uncharacterized protein. (162 aa)
	PY05852	Vac14_Fig4_bd domain-containing protein. (616 aa)
	PY05156	DNA-directed RNA polymerase beta chain. (863 aa)
	PY04367	Small GTP-binding protein; Belongs to the small GTPase superfamily. SAR1 family. (185 aa)
	PY04230	Adaptin_N domain-containing protein. (851 aa)
	PY04228	V-SNARE domain-containing protein. (213 aa)
	PY04027	Coatomer subunit zeta; The zeta subunit may be involved in regulating the coat assembly and, hence, the rate of biosynthetic protein transport due to its association-dissociation properties with the coatomer complex. (213 aa)
	PY03931	Uncharacterized protein. (185 aa)
	PY03930	WD_REPEATS_REGION domain-containing protein. (1249 aa)
	PY03895	Putative Sec24-like protein. (1396 aa)
	PY03775	WD_REPEATS_REGION domain-containing protein; Belongs to the WD repeat SEC13 family. (426 aa)
	PY03598	Uncharacterized protein. (42 aa)
	PY03532	Mic1 domain-containing protein. (792 aa)
	PY03384	GOP-1-related. (179 aa)
	PY03383	Uncharacterized protein. (929 aa)
	PY03382	Uncharacterized protein. (215 aa)
	PY02848	Uncharacterized protein. (151 aa)
	PY02624	Uncharacterized protein. (117 aa)
	PY02583	Adaptor complexes medium subunit family; Belongs to the adaptor complexes medium subunit family. (667 aa)
	PY02497	Protein transport protein SEC23; Component of the coat protein complex II (COPII) which promotes the formation of transport vesicles from the endoplasmic reticulum (ER). The coat has two main functions, the physical deformation of the endoplasmic reticulum membrane into vesicles and the selection of cargo molecules; Belongs to the SEC23/SEC24 family. SEC23 subfamily. (676 aa)
	PY02496	Protein transport protein SEC23; Component of the coat protein complex II (COPII) which promotes the formation of transport vesicles from the endoplasmic reticulum (ER). The coat has two main functions, the physical deformation of the endoplasmic reticulum membrane into vesicles and the selection of cargo molecules; Belongs to the SEC23/SEC24 family. SEC23 subfamily. (109 aa)
	PY02243	Uncharacterized protein. (162 aa)
	PY02242	CCAAT-box DNA binding protein subunit B. (388 aa)
	PY02241	Uncharacterized protein. (183 aa)
	PY02098	Vps53_N domain-containing protein. (790 aa)
	PY01892	Uncharacterized protein. (300 aa)
	PY01854	Clathrin heavy chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin heavy chain family. (2004 aa)
	PY01725	Uncharacterized protein. (1548 aa)
	PY01701	Clat_adaptor_s domain-containing protein. (63 aa)
	PY01700	Clat_adaptor_s domain-containing protein. (49 aa)
	PY01574	Uncharacterized protein; Belongs to the WD repeat SEC13 family. (597 aa)
	PY01512	Vta1 domain-containing protein. (253 aa)
	PY01387	Uncharacterized protein. (634 aa)
	PY01275	Nuclear protein snf7. (207 aa)
	PY01272	Coatomer beta subunit. (1286 aa)
	PY01094	Uncharacterized protein. (963 aa)
	PY01045	AlphaCop gene product. (1283 aa)
	PY00718	Coatomer subunit gamma; The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin- coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins. (995 aa)
	PY00672	Suppressor protein of bem1/bed5 double mutants; Belongs to the AAA ATPase family. (430 aa)
	PY00471	Coatomer subunit delta; The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin- coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins. (494 aa)
	PY00224	COPI_C domain-containing protein. (50 aa)

Your Current Organism:

Plasmodium yoelii

NCBI taxonomy Id: 73239
Other names: P. yoelii yoelii, Plasmodium yoelii subsp. yoelii, Plasmodium yoelii yoelii

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
PY00224	PY00471	Q7RSX8	Q7RS92	COPI_C domain-containing protein.	Coatomer subunit delta; The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin- coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins.	0.989
PY00224	PY00718	Q7RSX8	Q7RRK1	COPI_C domain-containing protein.	Coatomer subunit gamma; The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin- coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins.	0.988
PY00224	PY01094	Q7RSX8	Q7RQK2	COPI_C domain-containing protein.	Uncharacterized protein.	0.418
PY00224	PY01272	Q7RSX8	Q7RQ31	COPI_C domain-containing protein.	Coatomer beta subunit.	0.965
PY00224	PY01854	Q7RSX8	Q7RNG3	COPI_C domain-containing protein.	Clathrin heavy chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin heavy chain family.	0.580
PY00224	PY01892	Q7RSX8	Q7RNC8	COPI_C domain-containing protein.	Uncharacterized protein.	0.979
PY00224	PY02496	Q7RSX8	Q7RLP4	COPI_C domain-containing protein.	Protein transport protein SEC23; Component of the coat protein complex II (COPII) which promotes the formation of transport vesicles from the endoplasmic reticulum (ER). The coat has two main functions, the physical deformation of the endoplasmic reticulum membrane into vesicles and the selection of cargo molecules; Belongs to the SEC23/SEC24 family. SEC23 subfamily.	0.488
PY00224	PY02497	Q7RSX8	Q7RLP3	COPI_C domain-containing protein.	Protein transport protein SEC23; Component of the coat protein complex II (COPII) which promotes the formation of transport vesicles from the endoplasmic reticulum (ER). The coat has two main functions, the physical deformation of the endoplasmic reticulum membrane into vesicles and the selection of cargo molecules; Belongs to the SEC23/SEC24 family. SEC23 subfamily.	0.488
PY00224	PY02704	Q7RSX8	Q7RL43	COPI_C domain-containing protein.	Arabinogalactan protein.	0.518
PY00224	PY03930	Q7RSX8	Q7RHQ4	COPI_C domain-containing protein.	WD_REPEATS_REGION domain-containing protein.	0.460
PY00224	PY03931	Q7RSX8	Q7RHQ3	COPI_C domain-containing protein.	Uncharacterized protein.	0.460
PY00224	PY04027	Q7RSX8	Q7RHG0	COPI_C domain-containing protein.	Coatomer subunit zeta; The zeta subunit may be involved in regulating the coat assembly and, hence, the rate of biosynthetic protein transport due to its association-dissociation properties with the coatomer complex.	0.978
PY00224	PY05156	Q7RSX8	Q7REA9	COPI_C domain-containing protein.	DNA-directed RNA polymerase beta chain.	0.948
PY00224	PY05987	Q7RSX8	Q7RBZ8	COPI_C domain-containing protein.	Coatomer beta' subunit.	0.989
PY00471	PY00224	Q7RS92	Q7RSX8	Coatomer subunit delta; The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin- coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins.	COPI_C domain-containing protein.	0.989
PY00471	PY00718	Q7RS92	Q7RRK1	Coatomer subunit delta; The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin- coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins.	Coatomer subunit gamma; The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin- coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins.	0.999
PY00471	PY01045	Q7RS92	Q7RQP8	Coatomer subunit delta; The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin- coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins.	AlphaCop gene product.	0.989
PY00471	PY01094	Q7RS92	Q7RQK2	Coatomer subunit delta; The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin- coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins.	Uncharacterized protein.	0.506
PY00471	PY01272	Q7RS92	Q7RQ31	Coatomer subunit delta; The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin- coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins.	Coatomer beta subunit.	0.999
PY00471	PY01574	Q7RS92	Q7RP85	Coatomer subunit delta; The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin- coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins.	Uncharacterized protein; Belongs to the WD repeat SEC13 family.	0.435