(5 nodes) Box H/ACA RNP complex network (Musca domestica)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	A0A1I8MBT6	PUA domain-containing protein. (515 aa)
	A0A1I8MP59	WD_REPEATS_REGION domain-containing protein. (621 aa)
	A0A1I8MWB4	H/ACA ribonucleoprotein complex subunit; Required for ribosome biogenesis. Part of a complex which catalyzes pseudouridylation of rRNA. This involves the isomerization of uridine such that the ribose is subsequently attached to C5, instead of the normal N1. Pseudouridine ("psi") residues may serve to stabilize the conformation of rRNAs. (233 aa)
	A0A1I8NHT7	Uncharacterized protein. (64 aa)
	T1PGT4_MUSDO	Ribosomal protein L7Ae/L30e/S12e/Gadd47. (160 aa)

Your Current Organism:

Musca domestica

NCBI taxonomy Id: 7370
Other names: house fly

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
A0A1I8MBT6	A0A1I8MP59	A0A1I8MBT6	A0A1I8MP59	PUA domain-containing protein.	WD_REPEATS_REGION domain-containing protein.	0.983
A0A1I8MBT6	A0A1I8MWB4	A0A1I8MBT6	A0A1I8MWB4	PUA domain-containing protein.	H/ACA ribonucleoprotein complex subunit; Required for ribosome biogenesis. Part of a complex which catalyzes pseudouridylation of rRNA. This involves the isomerization of uridine such that the ribose is subsequently attached to C5, instead of the normal N1. Pseudouridine ("psi") residues may serve to stabilize the conformation of rRNAs.	0.999
A0A1I8MBT6	A0A1I8NHT7	A0A1I8MBT6	A0A1I8NHT7	PUA domain-containing protein.	Uncharacterized protein.	0.998
A0A1I8MBT6	T1PGT4_MUSDO	A0A1I8MBT6	T1PGT4	PUA domain-containing protein.	Ribosomal protein L7Ae/L30e/S12e/Gadd47.	0.999
A0A1I8MP59	A0A1I8MBT6	A0A1I8MP59	A0A1I8MBT6	WD_REPEATS_REGION domain-containing protein.	PUA domain-containing protein.	0.983
A0A1I8MP59	A0A1I8MWB4	A0A1I8MP59	A0A1I8MWB4	WD_REPEATS_REGION domain-containing protein.	H/ACA ribonucleoprotein complex subunit; Required for ribosome biogenesis. Part of a complex which catalyzes pseudouridylation of rRNA. This involves the isomerization of uridine such that the ribose is subsequently attached to C5, instead of the normal N1. Pseudouridine ("psi") residues may serve to stabilize the conformation of rRNAs.	0.962
A0A1I8MP59	A0A1I8NHT7	A0A1I8MP59	A0A1I8NHT7	WD_REPEATS_REGION domain-containing protein.	Uncharacterized protein.	0.942
A0A1I8MP59	T1PGT4_MUSDO	A0A1I8MP59	T1PGT4	WD_REPEATS_REGION domain-containing protein.	Ribosomal protein L7Ae/L30e/S12e/Gadd47.	0.964
A0A1I8MWB4	A0A1I8MBT6	A0A1I8MWB4	A0A1I8MBT6	H/ACA ribonucleoprotein complex subunit; Required for ribosome biogenesis. Part of a complex which catalyzes pseudouridylation of rRNA. This involves the isomerization of uridine such that the ribose is subsequently attached to C5, instead of the normal N1. Pseudouridine ("psi") residues may serve to stabilize the conformation of rRNAs.	PUA domain-containing protein.	0.999
A0A1I8MWB4	A0A1I8MP59	A0A1I8MWB4	A0A1I8MP59	H/ACA ribonucleoprotein complex subunit; Required for ribosome biogenesis. Part of a complex which catalyzes pseudouridylation of rRNA. This involves the isomerization of uridine such that the ribose is subsequently attached to C5, instead of the normal N1. Pseudouridine ("psi") residues may serve to stabilize the conformation of rRNAs.	WD_REPEATS_REGION domain-containing protein.	0.962
A0A1I8MWB4	A0A1I8NHT7	A0A1I8MWB4	A0A1I8NHT7	H/ACA ribonucleoprotein complex subunit; Required for ribosome biogenesis. Part of a complex which catalyzes pseudouridylation of rRNA. This involves the isomerization of uridine such that the ribose is subsequently attached to C5, instead of the normal N1. Pseudouridine ("psi") residues may serve to stabilize the conformation of rRNAs.	Uncharacterized protein.	0.998
A0A1I8MWB4	T1PGT4_MUSDO	A0A1I8MWB4	T1PGT4	H/ACA ribonucleoprotein complex subunit; Required for ribosome biogenesis. Part of a complex which catalyzes pseudouridylation of rRNA. This involves the isomerization of uridine such that the ribose is subsequently attached to C5, instead of the normal N1. Pseudouridine ("psi") residues may serve to stabilize the conformation of rRNAs.	Ribosomal protein L7Ae/L30e/S12e/Gadd47.	0.999
A0A1I8NHT7	A0A1I8MBT6	A0A1I8NHT7	A0A1I8MBT6	Uncharacterized protein.	PUA domain-containing protein.	0.998
A0A1I8NHT7	A0A1I8MP59	A0A1I8NHT7	A0A1I8MP59	Uncharacterized protein.	WD_REPEATS_REGION domain-containing protein.	0.942
A0A1I8NHT7	A0A1I8MWB4	A0A1I8NHT7	A0A1I8MWB4	Uncharacterized protein.	H/ACA ribonucleoprotein complex subunit; Required for ribosome biogenesis. Part of a complex which catalyzes pseudouridylation of rRNA. This involves the isomerization of uridine such that the ribose is subsequently attached to C5, instead of the normal N1. Pseudouridine ("psi") residues may serve to stabilize the conformation of rRNAs.	0.998
A0A1I8NHT7	T1PGT4_MUSDO	A0A1I8NHT7	T1PGT4	Uncharacterized protein.	Ribosomal protein L7Ae/L30e/S12e/Gadd47.	0.999
T1PGT4_MUSDO	A0A1I8MBT6	T1PGT4	A0A1I8MBT6	Ribosomal protein L7Ae/L30e/S12e/Gadd47.	PUA domain-containing protein.	0.999
T1PGT4_MUSDO	A0A1I8MP59	T1PGT4	A0A1I8MP59	Ribosomal protein L7Ae/L30e/S12e/Gadd47.	WD_REPEATS_REGION domain-containing protein.	0.964
T1PGT4_MUSDO	A0A1I8MWB4	T1PGT4	A0A1I8MWB4	Ribosomal protein L7Ae/L30e/S12e/Gadd47.	H/ACA ribonucleoprotein complex subunit; Required for ribosome biogenesis. Part of a complex which catalyzes pseudouridylation of rRNA. This involves the isomerization of uridine such that the ribose is subsequently attached to C5, instead of the normal N1. Pseudouridine ("psi") residues may serve to stabilize the conformation of rRNAs.	0.999
T1PGT4_MUSDO	A0A1I8NHT7	T1PGT4	A0A1I8NHT7	Ribosomal protein L7Ae/L30e/S12e/Gadd47.	Uncharacterized protein.	0.999