65 items (Musca domestica) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	A0A1I8MQ30	Uncharacterized protein. (119 aa)
	A0A1I8M0P9	Cytochrome b561 domain-containing protein. (352 aa)
	A0A1I8M0V4	V-type proton ATPase subunit a; Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase. (825 aa)
	A0A1I8M0V8	Uncharacterized protein. (865 aa)
	A0A1I8M124	t-SNARE coiled-coil homology domain-containing protein. (108 aa)
	A0A1I8M187	Uncharacterized protein. (2488 aa)
	A0A1I8M503	Phosphatidylinositol-4,5-bisphosphate 4-phosphatase; Catalyzes the hydrolysis of phosphatidylinositol-4,5- bisphosphate (PtdIns-4,5-P2) to phosphatidylinositol-4-phosphate (PtdIns-4-P). (270 aa)
	A0A1I8M5F0	Uncharacterized protein. (141 aa)
	A0A1I8M6E7	Robl_LC7 domain-containing protein. (128 aa)
	A0A1I8M704	Uncharacterized protein. (436 aa)
	A0A1I8M7T0	Uncharacterized protein. (194 aa)
	A0A1I8M849	Phosphatidylinositol 3-kinase catalytic subunit type 3. (959 aa)
	A0A1I8M986	Uncharacterized protein. (395 aa)
	A0A1I8M9F2	Cytochrome b561 domain-containing protein. (295 aa)
	A0A1I8MAP9	Uncharacterized protein. (154 aa)
	A0A1I8MB83	Uncharacterized protein. (407 aa)
	A0A1I8MD39	V-type proton ATPase subunit H; Subunit of the peripheral V1 complex of vacuolar ATPase. Subunit H activates ATPase activity of the enzyme and couples ATPase activity to proton flow. Vacuolar ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells, thus providing most of the energy required for transport processes in the vacuolar system. (471 aa)
	A0A1I8MEI3	Chloride channel protein. (851 aa)
	A0A1I8MFJ1	Uncharacterized protein. (292 aa)
	A0A1I8MFV6	Uncharacterized protein. (356 aa)
	A0A1I8MGL3	Uncharacterized protein. (318 aa)
	A0A1I8MH44	Uncharacterized protein. (1533 aa)
	A0A1I8MJ09	Uncharacterized protein. (131 aa)
	A0A1I8MK19	Uncharacterized protein. (92 aa)
	A0A1I8MLS3	Uncharacterized protein. (387 aa)
	A0A1I8MMH7	Uncharacterized protein. (120 aa)
	A0A1I8MMN2	Uncharacterized protein. (324 aa)
	A0A1I8MMT1	Uncharacterized protein. (259 aa)
	A0A1I8MNJ8	Uncharacterized protein. (326 aa)
	A0A1I8MPU6	Uncharacterized protein. (993 aa)
	A0A1I8MR22	Uncharacterized protein. (686 aa)
	A0A1I8MSZ2	Uncharacterized protein. (690 aa)
	A0A1I8MUE5	WD_REPEATS_REGION domain-containing protein. (781 aa)
	A0A1I8MUR3	Presenilin; Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors. Belongs to the peptidase A22A family. (523 aa)
	A0A1I8MUY4	Uncharacterized protein. (391 aa)
	A0A1I8N340	DAGKc domain-containing protein. (631 aa)
	A0A1I8N3I1	V-type proton ATPase subunit a; Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase. (858 aa)
	A0A1I8N3L5	Uncharacterized protein. (2083 aa)
	A0A1I8N4K1	Uncharacterized protein. (82 aa)
	A0A1I8N4L0	WD_REPEATS_REGION domain-containing protein. (609 aa)
	A0A1I8N637	DUF1624 domain-containing protein. (574 aa)
	A0A1I8N6D5	V-type proton ATPase subunit F; Subunit of the peripheral V1 complex of vacuolar ATPase essential for assembly or catalytic function. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells. (124 aa)
	A0A1I8N822	Uncharacterized protein; Belongs to the small GTPase superfamily. Arf family. (186 aa)
	A0A1I8N8L2	TLDc domain-containing protein. (465 aa)
	A0A1I8N9G7	Uncharacterized protein; Belongs to the CD36 family. (650 aa)
	A0A1I8NB13	V-type proton ATPase subunit a; Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase. (834 aa)
	A0A1I8NBB1	V-type proton ATPase subunit; Vacuolar ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells. (90 aa)
	A0A1I8NCQ4	t-SNARE coiled-coil homology domain-containing protein. (312 aa)
	A0A1I8ND12	FPL domain-containing protein. (1086 aa)
	A0A1I8NHL6	V-type proton ATPase subunit; Vacuolar ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells. (85 aa)
	A0A1I8NID9	SAC domain-containing protein. (869 aa)
	A0A1I8NIP1	V-type proton ATPase subunit a; Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase. (759 aa)
	A0A1I8NK25	Uncharacterized protein. (343 aa)
	T1PAZ3_MUSDO	V-type proton ATPase subunit; Subunit of the integral membrane V0 complex of vacuolar ATPase. Vacuolar ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells, thus providing most of the energy required for transport processes in the vacuolar system. Belongs to the V-ATPase V0D/AC39 subunit family. (350 aa)
	T1PB59_MUSDO	Vacuolar ATP synthase subunit S1 (ATP6S1). (383 aa)
	T1PBL3_MUSDO	Polycystin cation channel. (656 aa)
	T1PC18_MUSDO	Ras family protein. (218 aa)
	T1PDI0_MUSDO	ATP synthase subunit. (227 aa)
	T1PEY4_MUSDO	ATPase family associated protein; Belongs to the AAA ATPase family. (801 aa)
	T1PF56_MUSDO	Vacuolar proton pump subunit B; Non-catalytic subunit of the peripheral V1 complex of vacuolar ATPase; Belongs to the ATPase alpha/beta chains family. (492 aa)
	T1PG42_MUSDO	V-type proton ATPase subunit a; Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase. (830 aa)
	T1PHK5_MUSDO	ATP synthase. (614 aa)
	T1PHX4_MUSDO	ATP synthase subunit C; Belongs to the V-ATPase proteolipid subunit family. (211 aa)
	T1PP66_MUSDO	V-type proton ATPase subunit G; Catalytic subunit of the peripheral V1 complex of vacuolar ATPase (V-ATPase). V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells. (118 aa)
	T1PP69_MUSDO	V-type proton ATPase subunit C; Subunit of the peripheral V1 complex of vacuolar ATPase. Subunit C is necessary for the assembly of the catalytic sector of the enzyme and is likely to have a specific function in its catalytic activity. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells. (389 aa)

Your Current Organism:

Musca domestica

NCBI taxonomy Id: 7370
Other names: house fly

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
A0A1I8M0V4	A0A1I8MD39	A0A1I8M0V4	A0A1I8MD39	V-type proton ATPase subunit a; Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase.	V-type proton ATPase subunit H; Subunit of the peripheral V1 complex of vacuolar ATPase. Subunit H activates ATPase activity of the enzyme and couples ATPase activity to proton flow. Vacuolar ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells, thus providing most of the energy required for transport processes in the vacuolar system.	0.980
A0A1I8M0V4	A0A1I8MGL3	A0A1I8M0V4	A0A1I8MGL3	V-type proton ATPase subunit a; Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase.	Uncharacterized protein.	0.657
A0A1I8M0V4	A0A1I8N3I1	A0A1I8M0V4	A0A1I8N3I1	V-type proton ATPase subunit a; Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase.	V-type proton ATPase subunit a; Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase.	0.913
A0A1I8M0V4	A0A1I8N6D5	A0A1I8M0V4	A0A1I8N6D5	V-type proton ATPase subunit a; Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase.	V-type proton ATPase subunit F; Subunit of the peripheral V1 complex of vacuolar ATPase essential for assembly or catalytic function. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells.	0.930
A0A1I8M0V4	A0A1I8N8L2	A0A1I8M0V4	A0A1I8N8L2	V-type proton ATPase subunit a; Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase.	TLDc domain-containing protein.	0.491
A0A1I8M0V4	A0A1I8NB13	A0A1I8M0V4	A0A1I8NB13	V-type proton ATPase subunit a; Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase.	V-type proton ATPase subunit a; Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase.	0.914
A0A1I8M0V4	A0A1I8NBB1	A0A1I8M0V4	A0A1I8NBB1	V-type proton ATPase subunit a; Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase.	V-type proton ATPase subunit; Vacuolar ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells.	0.760
A0A1I8M0V4	A0A1I8NHL6	A0A1I8M0V4	A0A1I8NHL6	V-type proton ATPase subunit a; Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase.	V-type proton ATPase subunit; Vacuolar ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells.	0.760
A0A1I8M0V4	A0A1I8NIP1	A0A1I8M0V4	A0A1I8NIP1	V-type proton ATPase subunit a; Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase.	V-type proton ATPase subunit a; Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase.	0.907
A0A1I8M0V4	A0A1I8NK25	A0A1I8M0V4	A0A1I8NK25	V-type proton ATPase subunit a; Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase.	Uncharacterized protein.	0.662
A0A1I8M0V4	T1PAZ3_MUSDO	A0A1I8M0V4	T1PAZ3	V-type proton ATPase subunit a; Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase.	V-type proton ATPase subunit; Subunit of the integral membrane V0 complex of vacuolar ATPase. Vacuolar ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells, thus providing most of the energy required for transport processes in the vacuolar system. Belongs to the V-ATPase V0D/AC39 subunit family.	0.993
A0A1I8M0V4	T1PB59_MUSDO	A0A1I8M0V4	T1PB59	V-type proton ATPase subunit a; Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase.	Vacuolar ATP synthase subunit S1 (ATP6S1).	0.965
A0A1I8M0V4	T1PDI0_MUSDO	A0A1I8M0V4	T1PDI0	V-type proton ATPase subunit a; Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase.	ATP synthase subunit.	0.943
A0A1I8M0V4	T1PF56_MUSDO	A0A1I8M0V4	T1PF56	V-type proton ATPase subunit a; Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase.	Vacuolar proton pump subunit B; Non-catalytic subunit of the peripheral V1 complex of vacuolar ATPase; Belongs to the ATPase alpha/beta chains family.	0.936
A0A1I8M0V4	T1PG42_MUSDO	A0A1I8M0V4	T1PG42	V-type proton ATPase subunit a; Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase.	V-type proton ATPase subunit a; Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase.	0.908
A0A1I8M0V4	T1PHK5_MUSDO	A0A1I8M0V4	T1PHK5	V-type proton ATPase subunit a; Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase.	ATP synthase.	0.872
A0A1I8M0V4	T1PHX4_MUSDO	A0A1I8M0V4	T1PHX4	V-type proton ATPase subunit a; Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase.	ATP synthase subunit C; Belongs to the V-ATPase proteolipid subunit family.	0.989
A0A1I8M0V4	T1PP66_MUSDO	A0A1I8M0V4	T1PP66	V-type proton ATPase subunit a; Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase.	V-type proton ATPase subunit G; Catalytic subunit of the peripheral V1 complex of vacuolar ATPase (V-ATPase). V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells.	0.865
A0A1I8M0V4	T1PP69_MUSDO	A0A1I8M0V4	T1PP69	V-type proton ATPase subunit a; Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase.	V-type proton ATPase subunit C; Subunit of the peripheral V1 complex of vacuolar ATPase. Subunit C is necessary for the assembly of the catalytic sector of the enzyme and is likely to have a specific function in its catalytic activity. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells.	0.865
A0A1I8M124	A0A1I8MQ30	A0A1I8M124	A0A1I8MQ30	t-SNARE coiled-coil homology domain-containing protein.	Uncharacterized protein.	0.435