64 items (Musca domestica) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	A0A1I8MJU2	Uncharacterized protein. (1167 aa)
	A0A1I8M123	Uncharacterized protein. (237 aa)
	A0A1I8M2D0	BZIP domain-containing protein. (449 aa)
	A0A1I8M2V3	RING-type domain-containing protein. (456 aa)
	A0A1I8M3V4	J domain-containing protein. (2431 aa)
	A0A1I8M3W7	Receptor protein-tyrosine kinase. (1438 aa)
	A0A1I8M643	G_PROTEIN_RECEP_F1_2 domain-containing protein. (406 aa)
	A0A1I8M6E8	ORC_WH_C domain-containing protein. (724 aa)
	A0A1I8M849	Phosphatidylinositol 3-kinase catalytic subunit type 3. (959 aa)
	A0A1I8MC85	E2F_TDP domain-containing protein. (839 aa)
	A0A1I8MEW6	Protein kinase domain-containing protein. (1290 aa)
	A0A1I8MF96	Uncharacterized protein. (445 aa)
	A0A1I8MGE8	1,2-dihydroxy-3-keto-5-methylthiopentene dioxygenase; Catalyzes the formation of formate and 2-keto-4- methylthiobutyrate (KMTB) from 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene). (186 aa)
	A0A1I8MH44	Uncharacterized protein. (1533 aa)
	A0A1I8MHJ7	KA1 domain-containing protein. (182 aa)
	A0A1I8MHY2	Hepatocyte growth factor-regulated tyrosine kinase substrate; Essential role in endosome membrane invagination and formation of multivesicular bodies, MVBs. Required during gastrulation and appears to regulate early embryonic signaling pathways. Inhibits tyrosine kinase receptor signaling by promoting degradation of the tyrosine-phosphorylated, active receptor, potentially by sorting activated receptors into MVBs. The MVBs are then trafficked to the lysosome where their contents are degraded. (826 aa)
	A0A1I8MIH1	IPPc domain-containing protein. (355 aa)
	A0A1I8MME5	Receptor protein-tyrosine kinase. (1592 aa)
	A0A1I8MNR0	Beta-TrCP_D domain-containing protein. (99 aa)
	A0A1I8MPE3	Uncharacterized protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1840 aa)
	A0A1I8MQR6	EGF-like domain-containing protein. (281 aa)
	A0A1I8MQX9	Uncharacterized protein. (254 aa)
	A0A1I8MRB5	COesterase domain-containing protein. (1008 aa)
	A0A1I8MRZ3	ORC_WH_C domain-containing protein. (724 aa)
	A0A1I8MTE2	Uncharacterized protein. (498 aa)
	A0A1I8MUY4	Uncharacterized protein. (391 aa)
	A0A1I8MWJ9	G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family. (835 aa)
	A0A1I8MX15	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. Tyr protein kinase family. (1400 aa)
	A0A1I8MYX4	RING-type domain-containing protein. (206 aa)
	A0A1I8MZ76	BTB domain-containing protein. (727 aa)
	A0A1I8N025	Uncharacterized protein. (785 aa)
	A0A1I8N1A7	Nucleoporin_N domain-containing protein. (1395 aa)
	A0A1I8N2R0	Uncharacterized protein. (740 aa)
	A0A1I8N3A7	VIR_N domain-containing protein. (1902 aa)
	A0A1I8N3C6	Uncharacterized protein. (1984 aa)
	A0A1I8N3K4	Rhodanese domain-containing protein. (501 aa)
	A0A1I8N449	Non-specific serine/threonine protein kinase. (1013 aa)
	A0A1I8N4B1	EGF-like domain-containing protein. (194 aa)
	A0A1I8N4M1	Uncharacterized protein. (900 aa)
	A0A1I8N5K7	Uncharacterized protein. (1944 aa)
	A0A1I8N603	Uncharacterized protein. (134 aa)
	A0A1I8N6L2	Uncharacterized protein. (2230 aa)
	A0A1I8N748	DUF667 domain-containing protein. (199 aa)
	A0A1I8N7H3	Protein kinase domain-containing protein. (894 aa)
	A0A1I8N8B8	IPPc domain-containing protein. (508 aa)
	A0A1I8N8F0	Uncharacterized protein. (6040 aa)
	A0A1I8N8K8	Serine/threonine-protein kinase TOR; Belongs to the PI3/PI4-kinase family. (2493 aa)
	A0A1I8NAS8	UBA domain-containing protein. (411 aa)
	A0A1I8NBE5	1,2-dihydroxy-3-keto-5-methylthiopentene dioxygenase; Catalyzes the formation of formate and 2-keto-4- methylthiobutyrate (KMTB) from 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene). (186 aa)
	A0A1I8ND78	WD_REPEATS_REGION domain-containing protein. (524 aa)
	A0A1I8NDM0	F-box domain-containing protein. (752 aa)
	A0A1I8NDP7	Mitogen-activated protein kinase. (371 aa)
	A0A1I8NE79	Uncharacterized protein; Belongs to the PI3/PI4-kinase family. (1076 aa)
	A0A1I8NEI6	Uncharacterized protein. (1222 aa)
	A0A1I8NFS4	Uncharacterized protein. (360 aa)
	A0A1I8NGF6	Uncharacterized protein; Belongs to the DOCK family. (1995 aa)
	A0A1I8NL85	Uncharacterized protein. (119 aa)
	T1P884_MUSDO	Non-specific serine/threonine protein kinase. (522 aa)
	T1P976_MUSDO	Mitogen-activated protein kinase. (380 aa)
	T1PA53_MUSDO	RNA recognition protein. (422 aa)
	T1PBW8_MUSDO	Nucleoplasmin. (148 aa)
	T1PIB6_MUSDO	Autophagy-related protein 13; Belongs to the ATG13 family. Metazoan subfamily. (577 aa)
	T1PJX3_MUSDO	Dual specificity phosphatase. (399 aa)
	T1PPQ4_MUSDO	Nebulin repeat protein. (326 aa)

Your Current Organism:

Musca domestica

NCBI taxonomy Id: 7370
Other names: house fly

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
A0A1I8M123	A0A1I8M2D0	A0A1I8M123	A0A1I8M2D0	Uncharacterized protein.	BZIP domain-containing protein.	0.677
A0A1I8M123	A0A1I8MC85	A0A1I8M123	A0A1I8MC85	Uncharacterized protein.	E2F_TDP domain-containing protein.	0.794
A0A1I8M123	A0A1I8MTE2	A0A1I8M123	A0A1I8MTE2	Uncharacterized protein.	Uncharacterized protein.	0.598
A0A1I8M123	A0A1I8N3K4	A0A1I8M123	A0A1I8N3K4	Uncharacterized protein.	Rhodanese domain-containing protein.	0.572
A0A1I8M123	A0A1I8NGF6	A0A1I8M123	A0A1I8NGF6	Uncharacterized protein.	Uncharacterized protein; Belongs to the DOCK family.	0.403
A0A1I8M123	T1P884_MUSDO	A0A1I8M123	T1P884	Uncharacterized protein.	Non-specific serine/threonine protein kinase.	0.806
A0A1I8M2D0	A0A1I8M123	A0A1I8M2D0	A0A1I8M123	BZIP domain-containing protein.	Uncharacterized protein.	0.677
A0A1I8M3W7	A0A1I8MF96	A0A1I8M3W7	A0A1I8MF96	Receptor protein-tyrosine kinase.	Uncharacterized protein.	0.992
A0A1I8M3W7	A0A1I8MHY2	A0A1I8M3W7	A0A1I8MHY2	Receptor protein-tyrosine kinase.	Hepatocyte growth factor-regulated tyrosine kinase substrate; Essential role in endosome membrane invagination and formation of multivesicular bodies, MVBs. Required during gastrulation and appears to regulate early embryonic signaling pathways. Inhibits tyrosine kinase receptor signaling by promoting degradation of the tyrosine-phosphorylated, active receptor, potentially by sorting activated receptors into MVBs. The MVBs are then trafficked to the lysosome where their contents are degraded.	0.796
A0A1I8M3W7	A0A1I8MME5	A0A1I8M3W7	A0A1I8MME5	Receptor protein-tyrosine kinase.	Receptor protein-tyrosine kinase.	0.642
A0A1I8M3W7	A0A1I8MQR6	A0A1I8M3W7	A0A1I8MQR6	Receptor protein-tyrosine kinase.	EGF-like domain-containing protein.	0.985
A0A1I8M3W7	A0A1I8N2R0	A0A1I8M3W7	A0A1I8N2R0	Receptor protein-tyrosine kinase.	Uncharacterized protein.	0.996
A0A1I8M3W7	A0A1I8N4B1	A0A1I8M3W7	A0A1I8N4B1	Receptor protein-tyrosine kinase.	EGF-like domain-containing protein.	0.960
A0A1I8M3W7	A0A1I8NAS8	A0A1I8M3W7	A0A1I8NAS8	Receptor protein-tyrosine kinase.	UBA domain-containing protein.	0.927
A0A1I8M3W7	A0A1I8NE79	A0A1I8M3W7	A0A1I8NE79	Receptor protein-tyrosine kinase.	Uncharacterized protein; Belongs to the PI3/PI4-kinase family.	0.814
A0A1I8M3W7	T1P884_MUSDO	A0A1I8M3W7	T1P884	Receptor protein-tyrosine kinase.	Non-specific serine/threonine protein kinase.	0.456
A0A1I8M6E8	A0A1I8N3K4	A0A1I8M6E8	A0A1I8N3K4	ORC_WH_C domain-containing protein.	Rhodanese domain-containing protein.	0.755
A0A1I8M849	A0A1I8MHY2	A0A1I8M849	A0A1I8MHY2	Phosphatidylinositol 3-kinase catalytic subunit type 3.	Hepatocyte growth factor-regulated tyrosine kinase substrate; Essential role in endosome membrane invagination and formation of multivesicular bodies, MVBs. Required during gastrulation and appears to regulate early embryonic signaling pathways. Inhibits tyrosine kinase receptor signaling by promoting degradation of the tyrosine-phosphorylated, active receptor, potentially by sorting activated receptors into MVBs. The MVBs are then trafficked to the lysosome where their contents are degraded.	0.590
A0A1I8M849	A0A1I8N7H3	A0A1I8M849	A0A1I8N7H3	Phosphatidylinositol 3-kinase catalytic subunit type 3.	Protein kinase domain-containing protein.	0.990
A0A1I8M849	A0A1I8NE79	A0A1I8M849	A0A1I8NE79	Phosphatidylinositol 3-kinase catalytic subunit type 3.	Uncharacterized protein; Belongs to the PI3/PI4-kinase family.	0.665