(96 nodes) Precatalytic spliceosome network (Musca domestica)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	A0A1I8M387	Uncharacterized protein. (544 aa)
	A0A1I8M457	Uncharacterized protein; Belongs to the DEAD box helicase family. (623 aa)
	A0A1I8M487	TPR_REGION domain-containing protein. (939 aa)
	A0A1I8M5A7	SAM_Exu domain-containing protein. (514 aa)
	A0A1I8M5J8	CPSF_A domain-containing protein. (1225 aa)
	A0A1I8M5M3	Uncharacterized protein. (691 aa)
	T1PGR8_MUSDO	RNA recognition protein. (755 aa)
	T1PHZ3_MUSDO	Zinc-finger double-stranded RNA-binding protein. (678 aa)
	T1PI01_MUSDO	Pre-mRNA processing factor 3 (PRP3). (677 aa)
	T1PJC0_MUSDO	RNA recognition protein. (216 aa)
	T1PMK4_MUSDO	Zinc finger C-x8-C-x5-C-x3-H type. (852 aa)
	T1PNQ1_MUSDO	RNA recognition protein. (357 aa)
	A0A1I8M5P2	RRM domain-containing protein. (503 aa)
	A0A1I8M5X5	Uncharacterized protein. (275 aa)
	A0A1I8M8Y7	Uncharacterized protein. (1157 aa)
	A0A1I8M9J3	SKIP_SNW domain-containing protein. (545 aa)
	A0A1I8MAX0	DZF domain-containing protein. (907 aa)
	A0A1I8MAX5	Uncharacterized protein. (927 aa)
	A0A1I8MCY6	Peptidyl-prolyl cis-trans isomerase; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family. (183 aa)
	A0A1I8MD22	Uncharacterized protein. (785 aa)
	A0A1I8MEL0	Small nuclear ribonucleoprotein Sm D3. (147 aa)
	A0A1I8MG67	Uncharacterized protein. (1489 aa)
	A0A1I8MHE0	Peptidyl-prolyl cis-trans isomerase E; Catalyzes the cis-trans isomerization of proline imidic peptide bonds in proteins; Belongs to the cyclophilin-type PPIase family. PPIase E subfamily. (307 aa)
	A0A1I8MHL3	zf-C2HE domain-containing protein. (187 aa)
	A0A1I8MIN6	RRM domain-containing protein. (413 aa)
	A0A1I8MJ60	Uncharacterized protein. (907 aa)
	A0A1I8MJD7	G-patch domain-containing protein. (992 aa)
	A0A1I8MJW9	Uncharacterized protein. (1267 aa)
	A0A1I8MK54	WD_REPEATS_REGION domain-containing protein. (256 aa)
	A0A1I8MKJ6	G-patch domain-containing protein. (864 aa)
	A0A1I8MKM9	Tudor domain-containing protein. (239 aa)
	A0A1I8MKW2	RRM domain-containing protein. (575 aa)
	A0A1I8MLL7	Uncharacterized protein. (700 aa)
	A0A1I8MM19	SNRNP27 domain-containing protein. (186 aa)
	A0A1I8MM31	Uncharacterized protein. (256 aa)
	A0A1I8MMX9	Matrin-type domain-containing protein. (502 aa)
	A0A1I8MNM3	Uncharacterized protein; Belongs to the DEAD box helicase family. (699 aa)
	A0A1I8MP00	PPIase cyclophilin-type domain-containing protein. (498 aa)
	A0A1I8MPP3	Uncharacterized protein. (624 aa)
	A0A1I8MPP4	Uncharacterized protein. (599 aa)
	A0A1I8MPY7	Uncharacterized protein. (891 aa)
	A0A1I8MQL1	Cwf21 domain-containing protein. (1240 aa)
	A0A1I8MTD7	Uncharacterized protein. (2142 aa)
	A0A1I8MW31	PWI domain-containing protein. (1288 aa)
	A0A1I8MW33	Uncharacterized protein. (125 aa)
	A0A1I8MW62	RRM domain-containing protein. (314 aa)
	A0A1I8MW88	Uncharacterized protein. (628 aa)
	A0A1I8MWF9	Uncharacterized protein. (728 aa)
	A0A1I8MWG7	Peptidyl-prolyl cis-trans isomerase; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides. (588 aa)
	A0A1I8MX17	Uncharacterized protein. (331 aa)
	A0A1I8MYP6	Uncharacterized protein. (498 aa)
	A0A1I8MZC3	PPIase cyclophilin-type domain-containing protein. (942 aa)
	A0A1I8MZU4	DUF2040 domain-containing protein. (421 aa)
	A0A1I8N0G8	Uncharacterized protein. (406 aa)
	A0A1I8N0K5	Tr-type G domain-containing protein. (975 aa)
	A0A1I8N190	Peptidyl-prolyl cis-trans isomerase; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family. (178 aa)
	A0A1I8N1W6	FHA domain-containing protein. (408 aa)
	A0A1I8N4U9	KH_dom_type_1 domain-containing protein. (399 aa)
	A0A1I8N5C8	DUF667 domain-containing protein. (250 aa)
	A0A1I8N5D8	Uncharacterized protein. (329 aa)
	A0A1I8N623	CCHC-type domain-containing protein. (770 aa)
	A0A1I8N6I3	Kin17_mid domain-containing protein. (410 aa)
	A0A1I8N703	Uncharacterized protein. (237 aa)
	A0A1I8N748	DUF667 domain-containing protein. (199 aa)
	A0A1I8N7Q3	Uncharacterized protein. (386 aa)
	A0A1I8N8J8	Uncharacterized protein. (546 aa)
	A0A1I8N8S2	Uncharacterized protein. (144 aa)
	A0A1I8N9K0	Histone deacetylase complex subunit SAP18; Involved in the tethering of the SIN3 complex to core histone proteins. (149 aa)
	A0A1I8NAN6	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (394 aa)
	A0A1I8NBW8	CSD_1 domain-containing protein. (334 aa)
	A0A1I8NC98	RRM domain-containing protein. (166 aa)
	A0A1I8NDB1	RRM domain-containing protein. (262 aa)
	A0A1I8NDQ0	Uncharacterized protein. (927 aa)
	A0A1I8NFH5	WW domain-containing protein. (398 aa)
	A0A1I8NGH0	Uncharacterized protein. (344 aa)
	A0A1I8NHP8	MFAP1 domain-containing protein. (475 aa)
	A0A1I8NIN5	Uncharacterized protein. (1245 aa)
	A0A1I8NL64	WD_REPEATS_REGION domain-containing protein. (307 aa)
	tra2	Transformer 2. (232 aa)
	T1P8J3_MUSDO	PRP1 splicing factor. (931 aa)
	T1P8N3_MUSDO	DZF domain protein. (393 aa)
	T1PB52_MUSDO	RNA recognition protein. (334 aa)
	T1PBT6_MUSDO	5-formyltetrahydrofolate cyclo-ligase family. (548 aa)
	T1PCX1_MUSDO	Uncharacterized protein; Belongs to the argonaute family. (900 aa)
	T1PEY7_MUSDO	RNA recognition protein. (341 aa)
	T1PFI3_MUSDO	DEAD/DEAH box helicase; Belongs to the DEAD box helicase family. (611 aa)
	T1PG03_MUSDO	DEAD/DEAH box helicase; Belongs to the DEAD box helicase family. (400 aa)
	T1PG17_MUSDO	Polyadenylate-binding protein; Binds the poly(A) tail of mRNA. Belongs to the polyadenylate-binding protein type-1 family. (642 aa)
	T1PG33_MUSDO	RNA recognition protein. (245 aa)
	T1PGA1_MUSDO	RNA recognition protein. (586 aa)
	A0A1I8M0Y4	J domain-containing protein. (299 aa)
	A0A1I8M231	Uncharacterized protein. (259 aa)
	A0A1I8M2L6	Protein kinase domain-containing protein. (975 aa)
	A0A1I8M2N4	Sm domain-containing protein; Associated with the spliceosome snRNP U1, U2, U4/U6 and U5. Belongs to the snRNP Sm proteins family. (88 aa)
	A0A1I8M334	RRM domain-containing protein. (695 aa)
	A0A1I8M381	Uncharacterized protein. (816 aa)

Your Current Organism:

Musca domestica

NCBI taxonomy Id: 7370
Other names: house fly

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
A0A1I8M231	A0A1I8M2L6	A0A1I8M231	A0A1I8M2L6	Uncharacterized protein.	Protein kinase domain-containing protein.	0.620
A0A1I8M231	A0A1I8M2N4	A0A1I8M231	A0A1I8M2N4	Uncharacterized protein.	Sm domain-containing protein; Associated with the spliceosome snRNP U1, U2, U4/U6 and U5. Belongs to the snRNP Sm proteins family.	0.995
A0A1I8M231	A0A1I8M334	A0A1I8M231	A0A1I8M334	Uncharacterized protein.	RRM domain-containing protein.	0.491
A0A1I8M231	A0A1I8M381	A0A1I8M231	A0A1I8M381	Uncharacterized protein.	Uncharacterized protein.	0.748
A0A1I8M231	A0A1I8M387	A0A1I8M231	A0A1I8M387	Uncharacterized protein.	Uncharacterized protein.	0.475
A0A1I8M231	A0A1I8M5J8	A0A1I8M231	A0A1I8M5J8	Uncharacterized protein.	CPSF_A domain-containing protein.	0.996
A0A1I8M231	A0A1I8M9J3	A0A1I8M231	A0A1I8M9J3	Uncharacterized protein.	SKIP_SNW domain-containing protein.	0.987
A0A1I8M231	A0A1I8MAX5	A0A1I8M231	A0A1I8MAX5	Uncharacterized protein.	Uncharacterized protein.	0.986
A0A1I8M231	A0A1I8MCY6	A0A1I8M231	A0A1I8MCY6	Uncharacterized protein.	Peptidyl-prolyl cis-trans isomerase; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family.	0.562
A0A1I8M231	A0A1I8MEL0	A0A1I8M231	A0A1I8MEL0	Uncharacterized protein.	Small nuclear ribonucleoprotein Sm D3.	0.996
A0A1I8M231	A0A1I8MG67	A0A1I8M231	A0A1I8MG67	Uncharacterized protein.	Uncharacterized protein.	0.948
A0A1I8M231	A0A1I8MHE0	A0A1I8M231	A0A1I8MHE0	Uncharacterized protein.	Peptidyl-prolyl cis-trans isomerase E; Catalyzes the cis-trans isomerization of proline imidic peptide bonds in proteins; Belongs to the cyclophilin-type PPIase family. PPIase E subfamily.	0.734
A0A1I8M231	A0A1I8MJ60	A0A1I8M231	A0A1I8MJ60	Uncharacterized protein.	Uncharacterized protein.	0.989
A0A1I8M231	A0A1I8MJW9	A0A1I8M231	A0A1I8MJW9	Uncharacterized protein.	Uncharacterized protein.	0.806
A0A1I8M231	A0A1I8MK54	A0A1I8M231	A0A1I8MK54	Uncharacterized protein.	WD_REPEATS_REGION domain-containing protein.	0.896
A0A1I8M231	A0A1I8MKJ6	A0A1I8M231	A0A1I8MKJ6	Uncharacterized protein.	G-patch domain-containing protein.	0.923
A0A1I8M231	A0A1I8MKM9	A0A1I8M231	A0A1I8MKM9	Uncharacterized protein.	Tudor domain-containing protein.	0.824
A0A1I8M231	A0A1I8MMX9	A0A1I8M231	A0A1I8MMX9	Uncharacterized protein.	Matrin-type domain-containing protein.	0.959
A0A1I8M231	A0A1I8MP00	A0A1I8M231	A0A1I8MP00	Uncharacterized protein.	PPIase cyclophilin-type domain-containing protein.	0.891
A0A1I8M231	A0A1I8MPY7	A0A1I8M231	A0A1I8MPY7	Uncharacterized protein.	Uncharacterized protein.	0.917