29 items (Musca domestica) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	A0A1I8MXG2	Uncharacterized protein. (179 aa)
	A0A1I8MZ99	Uncharacterized protein. (201 aa)
	A0A1I8N028	Uncharacterized protein. (710 aa)
	A0A1I8MHY2	Hepatocyte growth factor-regulated tyrosine kinase substrate; Essential role in endosome membrane invagination and formation of multivesicular bodies, MVBs. Required during gastrulation and appears to regulate early embryonic signaling pathways. Inhibits tyrosine kinase receptor signaling by promoting degradation of the tyrosine-phosphorylated, active receptor, potentially by sorting activated receptors into MVBs. The MVBs are then trafficked to the lysosome where their contents are degraded. (826 aa)
	A0A1I8N6M7	Uncharacterized protein. (686 aa)
	A0A1I8N968	WD_REPEATS_REGION domain-containing protein. (416 aa)
	A0A1I8NAS8	UBA domain-containing protein. (411 aa)
	A0A1I8NAY4	Uncharacterized protein. (941 aa)
	A0A1I8NED9	Uncharacterized protein. (1428 aa)
	A0A1I8NIC7	Uncharacterized protein. (1456 aa)
	T1P887_MUSDO	Phosphotyrosine interaction domain protein. (457 aa)
	T1PCK0_MUSDO	BAR domain protein. (371 aa)
	T1PFW1_MUSDO	Ras family protein. (190 aa)
	A0A1I8M0I1	ENTH domain-containing protein. (920 aa)
	A0A1I8M3W7	Receptor protein-tyrosine kinase. (1438 aa)
	A0A1I8M438	Ubiquitin-like domain-containing protein. (128 aa)
	A0A1I8M5Q2	Tyrosine-protein phosphatase; Belongs to the protein-tyrosine phosphatase family. Non- receptor class subfamily. (980 aa)
	A0A1I8M7H0	Uncharacterized protein. (212 aa)
	A0A1I8M8P8	Ubiquitin-like domain-containing protein. (156 aa)
	A0A1I8MA11	Uncharacterized protein. (476 aa)
	A0A1I8ME98	Uncharacterized protein. (1048 aa)
	A0A1I8MF96	Uncharacterized protein. (445 aa)
	A0A1I8MJL9	Uncharacterized protein. (682 aa)
	A0A1I8MLJ5	Uncharacterized protein. (227 aa)
	A0A1I8MNF3	Uncharacterized protein. (444 aa)
	A0A1I8MQP9	PH domain-containing protein. (901 aa)
	A0A1I8MRT1	Uncharacterized protein. (1448 aa)
	A0A1I8MUS8	Uncharacterized protein. (1469 aa)
	A0A1I8MV41	Uncharacterized protein. (969 aa)

Your Current Organism:

Musca domestica

NCBI taxonomy Id: 7370
Other names: house fly

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structured XML interaction data, according to the 'PSI-MI' data standard

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

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a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
A0A1I8M0I1	A0A1I8M3W7	A0A1I8M0I1	A0A1I8M3W7	ENTH domain-containing protein.	Receptor protein-tyrosine kinase.	0.978
A0A1I8M0I1	A0A1I8M438	A0A1I8M0I1	A0A1I8M438	ENTH domain-containing protein.	Ubiquitin-like domain-containing protein.	0.604
A0A1I8M0I1	A0A1I8M7H0	A0A1I8M0I1	A0A1I8M7H0	ENTH domain-containing protein.	Uncharacterized protein.	0.869
A0A1I8M0I1	A0A1I8M8P8	A0A1I8M0I1	A0A1I8M8P8	ENTH domain-containing protein.	Ubiquitin-like domain-containing protein.	0.649
A0A1I8M0I1	A0A1I8MA11	A0A1I8M0I1	A0A1I8MA11	ENTH domain-containing protein.	Uncharacterized protein.	0.706
A0A1I8M0I1	A0A1I8MF96	A0A1I8M0I1	A0A1I8MF96	ENTH domain-containing protein.	Uncharacterized protein.	0.539
A0A1I8M0I1	A0A1I8MHY2	A0A1I8M0I1	A0A1I8MHY2	ENTH domain-containing protein.	Hepatocyte growth factor-regulated tyrosine kinase substrate; Essential role in endosome membrane invagination and formation of multivesicular bodies, MVBs. Required during gastrulation and appears to regulate early embryonic signaling pathways. Inhibits tyrosine kinase receptor signaling by promoting degradation of the tyrosine-phosphorylated, active receptor, potentially by sorting activated receptors into MVBs. The MVBs are then trafficked to the lysosome where their contents are degraded.	0.772
A0A1I8M0I1	A0A1I8MJL9	A0A1I8M0I1	A0A1I8MJL9	ENTH domain-containing protein.	Uncharacterized protein.	0.687
A0A1I8M0I1	A0A1I8N6M7	A0A1I8M0I1	A0A1I8N6M7	ENTH domain-containing protein.	Uncharacterized protein.	0.706
A0A1I8M0I1	A0A1I8NAS8	A0A1I8M0I1	A0A1I8NAS8	ENTH domain-containing protein.	UBA domain-containing protein.	0.539
A0A1I8M0I1	A0A1I8NAY4	A0A1I8M0I1	A0A1I8NAY4	ENTH domain-containing protein.	Uncharacterized protein.	0.629
A0A1I8M0I1	A0A1I8NIC7	A0A1I8M0I1	A0A1I8NIC7	ENTH domain-containing protein.	Uncharacterized protein.	0.997
A0A1I8M0I1	T1PCK0_MUSDO	A0A1I8M0I1	T1PCK0	ENTH domain-containing protein.	BAR domain protein.	0.652
A0A1I8M3W7	A0A1I8M0I1	A0A1I8M3W7	A0A1I8M0I1	Receptor protein-tyrosine kinase.	ENTH domain-containing protein.	0.978
A0A1I8M3W7	A0A1I8M5Q2	A0A1I8M3W7	A0A1I8M5Q2	Receptor protein-tyrosine kinase.	Tyrosine-protein phosphatase; Belongs to the protein-tyrosine phosphatase family. Non- receptor class subfamily.	0.609
A0A1I8M3W7	A0A1I8M7H0	A0A1I8M3W7	A0A1I8M7H0	Receptor protein-tyrosine kinase.	Uncharacterized protein.	0.999
A0A1I8M3W7	A0A1I8M8P8	A0A1I8M3W7	A0A1I8M8P8	Receptor protein-tyrosine kinase.	Ubiquitin-like domain-containing protein.	0.575
A0A1I8M3W7	A0A1I8MA11	A0A1I8M3W7	A0A1I8MA11	Receptor protein-tyrosine kinase.	Uncharacterized protein.	0.577
A0A1I8M3W7	A0A1I8ME98	A0A1I8M3W7	A0A1I8ME98	Receptor protein-tyrosine kinase.	Uncharacterized protein.	0.767
A0A1I8M3W7	A0A1I8MF96	A0A1I8M3W7	A0A1I8MF96	Receptor protein-tyrosine kinase.	Uncharacterized protein.	0.992