97 items (Musca domestica) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	A0A1I8M0I1	ENTH domain-containing protein. (920 aa)
	A0A1I8M0V7	DUF1681 domain-containing protein. (245 aa)
	A0A1I8M2G3	Uncharacterized protein. (1421 aa)
	A0A1I8M2W4	Uncharacterized protein. (523 aa)
	A0A1I8M3G4	MFS domain-containing protein. (596 aa)
	A0A1I8M3S5	AP complex subunit beta. (919 aa)
	A0A1I8M3W7	Receptor protein-tyrosine kinase. (1438 aa)
	A0A1I8M438	Ubiquitin-like domain-containing protein. (128 aa)
	A0A1I8M696	Uncharacterized protein. (1559 aa)
	A0A1I8M6J1	Uncharacterized protein. (4307 aa)
	A0A1I8M6R2	Uncharacterized protein. (811 aa)
	A0A1I8M7H0	Uncharacterized protein. (212 aa)
	A0A1I8M7L1	Uncharacterized protein. (1340 aa)
	A0A1I8M8B0	PID domain-containing protein. (2361 aa)
	A0A1I8M8P4	Uncharacterized protein. (1255 aa)
	A0A1I8M8P8	Ubiquitin-like domain-containing protein. (156 aa)
	A0A1I8M8X1	Clathrin light chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin light chain family. (225 aa)
	A0A1I8MA11	Uncharacterized protein. (476 aa)
	A0A1I8MAC0	MPN domain-containing protein. (359 aa)
	A0A1I8MB05	ENTH domain-containing protein. (210 aa)
	A0A1I8MBG1	Uncharacterized protein. (389 aa)
	A0A1I8MCD2	ENTH domain-containing protein. (802 aa)
	A0A1I8MCW9	CSN8_PSD8_EIF3K domain-containing protein. (173 aa)
	A0A1I8MD82	Uncharacterized protein. (455 aa)
	A0A1I8MDU5	Uncharacterized protein. (911 aa)
	A0A1I8MDU6	Uncharacterized protein. (1313 aa)
	A0A1I8MF77	Uncharacterized protein. (593 aa)
	A0A1I8MF96	Uncharacterized protein. (445 aa)
	A0A1I8MFK0	PCI domain-containing protein. (441 aa)
	A0A1I8MGL2	Arf-GAP domain-containing protein. (228 aa)
	A0A1I8MGS4	KxDL domain-containing protein. (222 aa)
	A0A1I8MH94	UBA domain-containing protein. (376 aa)
	A0A1I8MHY2	Hepatocyte growth factor-regulated tyrosine kinase substrate; Essential role in endosome membrane invagination and formation of multivesicular bodies, MVBs. Required during gastrulation and appears to regulate early embryonic signaling pathways. Inhibits tyrosine kinase receptor signaling by promoting degradation of the tyrosine-phosphorylated, active receptor, potentially by sorting activated receptors into MVBs. The MVBs are then trafficked to the lysosome where their contents are degraded. (826 aa)
	A0A1I8MI26	Uncharacterized protein. (1452 aa)
	A0A1I8MIC1	Uncharacterized protein; Belongs to the synaptobrevin family. (219 aa)
	A0A1I8MII4	G_PROTEIN_RECEP_F1_2 domain-containing protein. (514 aa)
	A0A1I8MJ14	AP-2 complex subunit alpha; Adaptins are components of the adapter complexes which link clathrin to receptors in coated vesicles. (932 aa)
	A0A1I8MJL9	Uncharacterized protein. (682 aa)
	A0A1I8MJN9	Arrestin_N domain-containing protein. (216 aa)
	A0A1I8MJP5	Arrestin_C domain-containing protein. (885 aa)
	A0A1I8MK47	Uncharacterized protein. (310 aa)
	A0A1I8ML98	Uncharacterized protein. (484 aa)
	A0A1I8MM06	G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family. (420 aa)
	A0A1I8MMA0	Uncharacterized protein. (1245 aa)
	A0A1I8MQJ6	Uncharacterized protein. (921 aa)
	A0A1I8MQQ0	Uncharacterized protein; Belongs to the G-protein coupled receptor 1 family. (1097 aa)
	A0A1I8MQY1	Uncharacterized protein. (1330 aa)
	A0A1I8MR29	Protein kinase domain-containing protein. (1568 aa)
	A0A1I8MTJ7	Uncharacterized protein. (977 aa)
	A0A1I8MU74	G_PROTEIN_RECEP_F1_2 domain-containing protein. (322 aa)
	A0A1I8MUZ3	Uncharacterized protein. (1409 aa)
	A0A1I8MVC9	G_PROTEIN_RECEP_F1_2 domain-containing protein. (314 aa)
	A0A1I8MVH8	PCI domain-containing protein. (167 aa)
	A0A1I8MVP6	Uncharacterized protein. (333 aa)
	A0A1I8MVV2	C-type lectin domain-containing protein. (731 aa)
	A0A1I8MWM7	Clathrin heavy chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin heavy chain family. (1678 aa)
	A0A1I8MZI6	Uncharacterized protein. (342 aa)
	A0A1I8N043	Uncharacterized protein. (650 aa)
	A0A1I8N3I8	Uncharacterized protein. (412 aa)
	A0A1I8N3N0	Uncharacterized protein; Belongs to the CD36 family. (490 aa)
	A0A1I8N3V9	Uncharacterized protein. (732 aa)
	A0A1I8N4B3	Uncharacterized protein. (1366 aa)
	A0A1I8N4D3	Uncharacterized protein. (783 aa)
	A0A1I8N4P0	Uncharacterized protein. (258 aa)
	A0A1I8N4T2	PCI domain-containing protein. (500 aa)
	A0A1I8N5W3	V-SNARE coiled-coil homology domain-containing protein. (156 aa)
	A0A1I8N6M7	Uncharacterized protein. (686 aa)
	A0A1I8N820	G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family. (880 aa)
	A0A1I8N8D2	V-SNARE coiled-coil homology domain-containing protein. (125 aa)
	A0A1I8N8R3	MPN domain-containing protein. (334 aa)
	A0A1I8N9B6	PCI domain-containing protein. (408 aa)
	A0A1I8NA29	AP complex subunit sigma; Belongs to the adaptor complexes small subunit family. (142 aa)
	A0A1I8NA67	Arrestin_C domain-containing protein. (363 aa)
	A0A1I8NAJ3	Uncharacterized protein. (1368 aa)
	A0A1I8NAS8	UBA domain-containing protein. (411 aa)
	A0A1I8NAY4	Uncharacterized protein. (941 aa)
	A0A1I8NB02	Ubiquitin-like domain-containing protein. (78 aa)
	A0A1I8NB24	MANSC domain-containing protein. (1095 aa)
	A0A1I8NCB5	PID domain-containing protein. (301 aa)
	A0A1I8NCT0	Uncharacterized protein. (1326 aa)
	A0A1I8ND88	Uncharacterized protein. (1175 aa)
	A0A1I8NEB4	Uncharacterized protein. (344 aa)
	A0A1I8NFU7	Uncharacterized protein. (1303 aa)
	A0A1I8NGB8	ANTH domain-containing protein. (126 aa)
	A0A1I8NGG7	Uncharacterized protein. (1345 aa)
	A0A1I8NH46	Uncharacterized protein; Belongs to the G-protein coupled receptor 1 family. (1673 aa)
	A0A1I8NHN7	Uncharacterized protein. (600 aa)
	A0A1I8NI62	Uncharacterized protein. (1351 aa)
	A0A1I8NIC7	Uncharacterized protein. (1456 aa)
	A0A1I8NII3	AAA domain-containing protein. (343 aa)
	A0A1I8NJV0	CSN7a_helixI domain-containing protein. (105 aa)
	T1PCK0_MUSDO	BAR domain protein. (371 aa)
	T1PDM2_MUSDO	MHD domain-containing protein; Belongs to the adaptor complexes medium subunit family. (437 aa)
	T1PE77_MUSDO	Synaptobrevin. (175 aa)
	T1PF02_MUSDO	Arrestin (Or S-antigen). (402 aa)
	T1PGN9_MUSDO	PCI domain protein. (444 aa)
	T1PM66_MUSDO	Arrestin (Or S-antigen). (477 aa)

Your Current Organism:

Musca domestica

NCBI taxonomy Id: 7370
Other names: house fly

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
A0A1I8M0I1	A0A1I8M0V7	A0A1I8M0I1	A0A1I8M0V7	ENTH domain-containing protein.	DUF1681 domain-containing protein.	0.614
A0A1I8M0I1	A0A1I8M2W4	A0A1I8M0I1	A0A1I8M2W4	ENTH domain-containing protein.	Uncharacterized protein.	0.714
A0A1I8M0I1	A0A1I8M3S5	A0A1I8M0I1	A0A1I8M3S5	ENTH domain-containing protein.	AP complex subunit beta.	0.791
A0A1I8M0I1	A0A1I8M3W7	A0A1I8M0I1	A0A1I8M3W7	ENTH domain-containing protein.	Receptor protein-tyrosine kinase.	0.978
A0A1I8M0I1	A0A1I8M438	A0A1I8M0I1	A0A1I8M438	ENTH domain-containing protein.	Ubiquitin-like domain-containing protein.	0.604
A0A1I8M0I1	A0A1I8M6R2	A0A1I8M0I1	A0A1I8M6R2	ENTH domain-containing protein.	Uncharacterized protein.	0.470
A0A1I8M0I1	A0A1I8M7H0	A0A1I8M0I1	A0A1I8M7H0	ENTH domain-containing protein.	Uncharacterized protein.	0.869
A0A1I8M0I1	A0A1I8M8B0	A0A1I8M0I1	A0A1I8M8B0	ENTH domain-containing protein.	PID domain-containing protein.	0.622
A0A1I8M0I1	A0A1I8M8P4	A0A1I8M0I1	A0A1I8M8P4	ENTH domain-containing protein.	Uncharacterized protein.	0.706
A0A1I8M0I1	A0A1I8M8P8	A0A1I8M0I1	A0A1I8M8P8	ENTH domain-containing protein.	Ubiquitin-like domain-containing protein.	0.649
A0A1I8M0I1	A0A1I8M8X1	A0A1I8M0I1	A0A1I8M8X1	ENTH domain-containing protein.	Clathrin light chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin light chain family.	0.922
A0A1I8M0I1	A0A1I8MA11	A0A1I8M0I1	A0A1I8MA11	ENTH domain-containing protein.	Uncharacterized protein.	0.706
A0A1I8M0I1	A0A1I8MB05	A0A1I8M0I1	A0A1I8MB05	ENTH domain-containing protein.	ENTH domain-containing protein.	0.664
A0A1I8M0I1	A0A1I8MCD2	A0A1I8M0I1	A0A1I8MCD2	ENTH domain-containing protein.	ENTH domain-containing protein.	0.664
A0A1I8M0I1	A0A1I8MD82	A0A1I8M0I1	A0A1I8MD82	ENTH domain-containing protein.	Uncharacterized protein.	0.604
A0A1I8M0I1	A0A1I8MF96	A0A1I8M0I1	A0A1I8MF96	ENTH domain-containing protein.	Uncharacterized protein.	0.539
A0A1I8M0I1	A0A1I8MGL2	A0A1I8M0I1	A0A1I8MGL2	ENTH domain-containing protein.	Arf-GAP domain-containing protein.	0.470
A0A1I8M0I1	A0A1I8MH94	A0A1I8M0I1	A0A1I8MH94	ENTH domain-containing protein.	UBA domain-containing protein.	0.552
A0A1I8M0I1	A0A1I8MHY2	A0A1I8M0I1	A0A1I8MHY2	ENTH domain-containing protein.	Hepatocyte growth factor-regulated tyrosine kinase substrate; Essential role in endosome membrane invagination and formation of multivesicular bodies, MVBs. Required during gastrulation and appears to regulate early embryonic signaling pathways. Inhibits tyrosine kinase receptor signaling by promoting degradation of the tyrosine-phosphorylated, active receptor, potentially by sorting activated receptors into MVBs. The MVBs are then trafficked to the lysosome where their contents are degraded.	0.772
A0A1I8M0I1	A0A1I8MIC1	A0A1I8M0I1	A0A1I8MIC1	ENTH domain-containing protein.	Uncharacterized protein; Belongs to the synaptobrevin family.	0.558