47 items (Musca domestica) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	A0A1I8M0T8	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1247 aa)
	A0A1I8M1M3	Kinase; Belongs to the inositol phosphokinase (IPK) family. (1167 aa)
	A0A1I8M351	IPPc domain-containing protein. (691 aa)
	A0A1I8M503	Phosphatidylinositol-4,5-bisphosphate 4-phosphatase; Catalyzes the hydrolysis of phosphatidylinositol-4,5- bisphosphate (PtdIns-4,5-P2) to phosphatidylinositol-4-phosphate (PtdIns-4-P). (270 aa)
	A0A1I8M646	PIPK domain-containing protein. (753 aa)
	A0A1I8M7D1	Uncharacterized protein. (167 aa)
	A0A1I8M7W2	Uncharacterized protein. (1866 aa)
	A0A1I8M849	Phosphatidylinositol 3-kinase catalytic subunit type 3. (959 aa)
	A0A1I8M8C7	Uncharacterized protein; Belongs to the PI3/PI4-kinase family. (1967 aa)
	A0A1I8M8W2	Uncharacterized protein; Belongs to the PI3/PI4-kinase family. (2131 aa)
	A0A1I8M937	Myotubularin phosphatase domain-containing protein. (625 aa)
	A0A1I8MAD6	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1095 aa)
	A0A1I8MB48	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1294 aa)
	A0A1I8MCX1	CDP-diacylglycerol--inositol 3-phosphatidyltransferase. (224 aa)
	A0A1I8MDR5	Uncharacterized protein. (1325 aa)
	A0A1I8MFF1	Uncharacterized protein. (913 aa)
	A0A1I8MFI7	SAC domain-containing protein. (1231 aa)
	A0A1I8MFP5	Uncharacterized protein; Belongs to the PI3/PI4-kinase family. (1825 aa)
	A0A1I8MFZ0	Diacylglycerol kinase. (1712 aa)
	A0A1I8MLG1	Uncharacterized protein. (833 aa)
	A0A1I8MM18	PIPK domain-containing protein. (871 aa)
	A0A1I8MQQ1	Uncharacterized protein. (149 aa)
	A0A1I8MSK8	Inositol-1-monophosphatase. (280 aa)
	A0A1I8MSW0	Uncharacterized protein. (838 aa)
	A0A1I8MUE4	Uncharacterized protein. (551 aa)
	A0A1I8MV79	Uncharacterized protein. (1528 aa)
	A0A1I8MXV0	Uncharacterized protein. (383 aa)
	A0A1I8MZU3	Diacylglycerol kinase. (1375 aa)
	A0A1I8N1X9	Diacylglycerol kinase. (535 aa)
	A0A1I8N294	Kinase; Belongs to the inositol phosphokinase (IPK) family. (443 aa)
	A0A1I8N4D4	Kinase; Belongs to the inositol phosphokinase (IPK) family. (339 aa)
	A0A1I8N5E0	Uncharacterized protein. (773 aa)
	A0A1I8N5Q4	Uncharacterized protein. (2886 aa)
	A0A1I8N884	Uncharacterized protein. (367 aa)
	A0A1I8N8G0	Diacylglycerol kinase. (912 aa)
	A0A1I8NB72	Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (697 aa)
	A0A1I8NCC5	PIPK domain-containing protein. (403 aa)
	A0A1I8NDY6	IPPc domain-containing protein. (805 aa)
	A0A1I8NE79	Uncharacterized protein; Belongs to the PI3/PI4-kinase family. (1076 aa)
	A0A1I8NH55	Kinase; Belongs to the inositol phosphokinase (IPK) family. (671 aa)
	T1P9V2_MUSDO	Phosphatidate cytidylyltransferase; Belongs to the CDS family. (460 aa)
	T1PA60_MUSDO	SacI-like protein. (588 aa)
	T1PE82_MUSDO	Myotubularin Y phosphatase-like protein. (820 aa)
	T1PFJ3_MUSDO	Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (677 aa)
	T1PI58_MUSDO	Inositol-1-monophosphatase. (285 aa)
	T1PI68_MUSDO	Inositol-1-monophosphatase. (285 aa)
	T1PNX0_MUSDO	EF hand protein; Belongs to the calmodulin family. (149 aa)

Your Current Organism:

Musca domestica

NCBI taxonomy Id: 7370
Other names: house fly

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
A0A1I8M0T8	A0A1I8M351	A0A1I8M0T8	A0A1I8M351	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades.	IPPc domain-containing protein.	0.918
A0A1I8M0T8	A0A1I8M646	A0A1I8M0T8	A0A1I8M646	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades.	PIPK domain-containing protein.	0.918
A0A1I8M0T8	A0A1I8M7W2	A0A1I8M0T8	A0A1I8M7W2	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades.	Uncharacterized protein.	0.900
A0A1I8M0T8	A0A1I8M849	A0A1I8M0T8	A0A1I8M849	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades.	Phosphatidylinositol 3-kinase catalytic subunit type 3.	0.900
A0A1I8M0T8	A0A1I8M8C7	A0A1I8M0T8	A0A1I8M8C7	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades.	Uncharacterized protein; Belongs to the PI3/PI4-kinase family.	0.901
A0A1I8M0T8	A0A1I8M8W2	A0A1I8M0T8	A0A1I8M8W2	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades.	Uncharacterized protein; Belongs to the PI3/PI4-kinase family.	0.900
A0A1I8M0T8	A0A1I8M937	A0A1I8M0T8	A0A1I8M937	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades.	Myotubularin phosphatase domain-containing protein.	0.900
A0A1I8M0T8	A0A1I8MAD6	A0A1I8M0T8	A0A1I8MAD6	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades.	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes.	0.954
A0A1I8M0T8	A0A1I8MB48	A0A1I8M0T8	A0A1I8MB48	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades.	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes.	0.914
A0A1I8M0T8	A0A1I8MCX1	A0A1I8M0T8	A0A1I8MCX1	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades.	CDP-diacylglycerol--inositol 3-phosphatidyltransferase.	0.900
A0A1I8M0T8	A0A1I8MDR5	A0A1I8M0T8	A0A1I8MDR5	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades.	Uncharacterized protein.	0.916
A0A1I8M0T8	A0A1I8MFF1	A0A1I8M0T8	A0A1I8MFF1	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades.	Uncharacterized protein.	0.920
A0A1I8M0T8	A0A1I8MFI7	A0A1I8M0T8	A0A1I8MFI7	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades.	SAC domain-containing protein.	0.900
A0A1I8M0T8	A0A1I8MFP5	A0A1I8M0T8	A0A1I8MFP5	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades.	Uncharacterized protein; Belongs to the PI3/PI4-kinase family.	0.904
A0A1I8M0T8	A0A1I8MFZ0	A0A1I8M0T8	A0A1I8MFZ0	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades.	Diacylglycerol kinase.	0.906
A0A1I8M0T8	A0A1I8MM18	A0A1I8M0T8	A0A1I8MM18	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades.	PIPK domain-containing protein.	0.919
A0A1I8M0T8	A0A1I8MSK8	A0A1I8M0T8	A0A1I8MSK8	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades.	Inositol-1-monophosphatase.	0.900
A0A1I8M0T8	A0A1I8MSW0	A0A1I8M0T8	A0A1I8MSW0	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades.	Uncharacterized protein.	0.901
A0A1I8M0T8	A0A1I8MUE4	A0A1I8M0T8	A0A1I8MUE4	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades.	Uncharacterized protein.	0.936
A0A1I8M0T8	A0A1I8MV79	A0A1I8M0T8	A0A1I8MV79	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades.	Uncharacterized protein.	0.903