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rpsE rpsE rpmF rpmF rpsF rpsF rplU rplU metE metE rpmE rpmE rpmG rpmG rpmB rpmB rplQ rplQ rpsD rpsD rpsK rpsK GCA_001059425_00307 GCA_001059425_00307 rpmJ rpmJ rplO rplO rpmD rpmD rpsA rpsA rpmH rpmH rpsU rpsU tig2 tig2 dapF2 dapF2 rpmA rpmA rpmJ-2 rpmJ-2 rpmE2 rpmE2 rpmI rpmI ppa2 ppa2 rplL rplL rplJ rplJ rplA rplA rplK rplK rpsP rpsP argB argB rpsB rpsB yhiN yhiN GCA_001059425_00822 GCA_001059425_00822 rplM rplM rpsI rpsI rplY rplY rpsG rpsG rpsL rpsL rpsJ rpsJ rplC rplC rplD rplD rplW rplW rplB rplB rpsS rpsS rplV rplV rpsC rpsC rplP rplP rpmC rpmC rpsQ rpsQ rplN rplN rplX rplX rplE rplE rpsN rpsN rpsH rpsH rplF rplF rplR rplR
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
rpsEUnannotated protein; Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body. Belongs to the universal ribosomal protein uS5 family. (166 aa)
rpmFUnannotated protein; Belongs to the bacterial ribosomal protein bL32 family. (56 aa)
rpsFUnannotated protein; Binds together with S18 to 16S ribosomal RNA. (125 aa)
rplUUnannotated protein; Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit; Belongs to the bacterial ribosomal protein bS18 family. (76 aa)
metEUnannotated protein; Binds to the 23S rRNA. (149 aa)
rpmEUnannotated protein; Binds the 23S rRNA. (70 aa)
rpmGUnannotated protein; Belongs to the bacterial ribosomal protein bL33 family. (56 aa)
rpmBUnannotated protein; Belongs to the bacterial ribosomal protein bL28 family. (78 aa)
rplQUnannotated protein. (129 aa)
rpsDUnannotated protein; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit. (206 aa)
rpsKUnannotated protein; Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine- Dalgarno cleft in the 70S ribosome; Belongs to the universal ribosomal protein uS11 family. (129 aa)
GCA_001059425_00307Unannotated protein. (118 aa)
rpmJUnannotated protein; Belongs to the bacterial ribosomal protein bL36 family. (37 aa)
rplOUnannotated protein; Binds to the 23S rRNA; Belongs to the universal ribosomal protein uL15 family. (144 aa)
rpmDUnannotated protein. (59 aa)
rpsAUnannotated protein; Binds mRNA; thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence. (548 aa)
rpmHUnannotated protein; Belongs to the bacterial ribosomal protein bL34 family. (44 aa)
rpsUUnannotated protein; Belongs to the bacterial ribosomal protein bS21 family. (71 aa)
tig2Unannotated protein; Binds directly to 16S ribosomal RNA. (87 aa)
dapF2Unannotated protein; This protein binds to 23S rRNA in the presence of protein L20; Belongs to the bacterial ribosomal protein bL21 family. (103 aa)
rpmAUnannotated protein; Belongs to the bacterial ribosomal protein bL27 family. (85 aa)
rpmJ-2Unannotated protein; Belongs to the bacterial ribosomal protein bL36 family. (46 aa)
rpmE2Unannotated protein. (88 aa)
rpmIUnannotated protein; Belongs to the bacterial ribosomal protein bL35 family. (65 aa)
ppa2Unannotated protein; Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit. (117 aa)
rplLUnannotated protein; Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation; Belongs to the bacterial ribosomal protein bL12 family. (123 aa)
rplJUnannotated protein; Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors. Belongs to the universal ribosomal protein uL10 family. (163 aa)
rplAUnannotated protein; Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release. (229 aa)
rplKUnannotated protein; Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. (142 aa)
rpsPUnannotated protein; Belongs to the bacterial ribosomal protein bS16 family. (82 aa)
argBUnannotated protein; This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site. (116 aa)
rpsBUnannotated protein; Belongs to the universal ribosomal protein uS2 family. (240 aa)
yhiNUnannotated protein. (400 aa)
GCA_001059425_00822Unannotated protein. (89 aa)
rplMUnannotated protein; This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly. (142 aa)
rpsIUnannotated protein; Belongs to the universal ribosomal protein uS9 family. (130 aa)
rplYUnannotated protein; This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance. Belongs to the bacterial ribosomal protein bL25 family. (95 aa)
rpsGUnannotated protein; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA; Belongs to the universal ribosomal protein uS7 family. (156 aa)
rpsLUnannotated protein; Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit. (124 aa)
rpsJUnannotated protein; Involved in the binding of tRNA to the ribosomes. Belongs to the universal ribosomal protein uS10 family. (103 aa)
rplCUnannotated protein; One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit. (208 aa)
rplDUnannotated protein; Forms part of the polypeptide exit tunnel. (200 aa)
rplWUnannotated protein; One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome; Belongs to the universal ribosomal protein uL23 family. (100 aa)
rplBUnannotated protein; One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome. Belongs to the universal ribosomal protein uL2 family. (273 aa)
rpsSUnannotated protein; Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA. (91 aa)
rplVUnannotated protein; The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome. (110 aa)
rpsCUnannotated protein; Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation; Belongs to the universal ribosomal protein uS3 family. (235 aa)
rplPUnannotated protein; Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs; Belongs to the universal ribosomal protein uL16 family. (136 aa)
rpmCUnannotated protein; Belongs to the universal ribosomal protein uL29 family. (63 aa)
rpsQUnannotated protein; One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA. (85 aa)
rplNUnannotated protein; Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome; Belongs to the universal ribosomal protein uL14 family. (123 aa)
rplXUnannotated protein; One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit. (103 aa)
rplEUnannotated protein; This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs. (179 aa)
rpsNUnannotated protein; Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site; Belongs to the universal ribosomal protein uS14 family. (101 aa)
rpsHUnannotated protein; One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit; Belongs to the universal ribosomal protein uS8 family. (130 aa)
rplFUnannotated protein; This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center; Belongs to the universal ribosomal protein uL6 family. (177 aa)
rplRUnannotated protein; This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. (117 aa)
Your Current Organism:
Aggregatibacter segnis
NCBI taxonomy Id: 739
Other names: A. segnis, ATCC 33393, CCUG 10787, CCUG 12838, CIP 103292, DSM 21418, Haemophilus segnis, NCTC 10977, strain HK 316, strain HK316
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