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surE1 surE1 ADW20717.1 ADW20717.1 ADW20718.1 ADW20718.1 ADW20813.1 ADW20813.1 acoB acoB acoA acoA sucB sucB ADW20922.1 ADW20922.1 ADW21046.1 ADW21046.1 lon1 lon1 ADW21090.1 ADW21090.1 deoD deoD ADW21214.1 ADW21214.1 rocF rocF ADW21282.1 ADW21282.1 gcvT gcvT gcvH gcvH gcvPA gcvPA gcvPB gcvPB ADW21411.1 ADW21411.1 cdd cdd lon2 lon2 hslV hslV dtd dtd ADW21668.1 ADW21668.1 ADW21690.1 ADW21690.1 ADW21822.1 ADW21822.1 ADW21833.1 ADW21833.1 aepA aepA amiD amiD ADW22127.1 ADW22127.1 ADW22128.1 ADW22128.1 pdxT pdxT ADW22286.1 ADW22286.1 surE3 surE3 ADW22393.1 ADW22393.1 lon3 lon3 ftsH1 ftsH1 mtnN mtnN ADW22553.1 ADW22553.1 ftsH2 ftsH2 ADW22663.1 ADW22663.1 ADW22759.1 ADW22759.1 coaBC coaBC gdhA1 gdhA1 ald1 ald1 ADW22868.1 ADW22868.1 ADW22869.1 ADW22869.1 ADW22879.1 ADW22879.1 ald2 ald2 speA speA
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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surE15'/3'-nucleotidase SurE; Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates; Belongs to the SurE nucleotidase family. (249 aa)
ADW20717.1Nucleoside triphosphate pyrophosphohydrolase. (198 aa)
ADW20718.1MutT/nudix family protein; Belongs to the Nudix hydrolase family. (156 aa)
ADW20813.1Isochorismatase hydrolase. (196 aa)
acoB2-oxoisovalerate dehydrogenase, subunit beta; Bckdhe1-beta; branched-chain alpha-keto acid dehydrogenase e1 component beta chain. (324 aa)
acoA2-oxoisovalerate dehydrogenase, subunit alpha; Bckdhe1-alpha; branched-chain alpha-keto acid dehydrogenase e1 component alpha chain. (367 aa)
sucBDihydrolipoyllysine-residue succinyltransferase, E2 component of oxoglutarate dehydrogenase complex; E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2- oxoglutarate to succinyl-CoA and CO(2). (402 aa)
ADW20922.1L-threo-3-hydroxyaspartate dehydratase. (312 aa)
ADW21046.1Chloromuconate cycloisomerase; Belongs to the mandelate racemase/muconate lactonizing enzyme family. (359 aa)
lon1ATP-dependent protease La. (695 aa)
ADW21090.1Conserved hypothetical protein. (123 aa)
deoDPurine nucleoside phosphorylase DeoD-type; PNP. (235 aa)
ADW21214.1dNTP triphosphohydrolase; Belongs to the dGTPase family. Type 2 subfamily. (376 aa)
rocFArginase; Belongs to the arginase family. (327 aa)
ADW21282.1Putative endoribonuclease L-PSP. (124 aa)
gcvTGlycine cleavage system T protein; The glycine cleavage system catalyzes the degradation of glycine. (349 aa)
gcvHGlycine cleavage system H protein; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein. (128 aa)
gcvPAGlycine decarboxylase, subunit 1; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein. (438 aa)
gcvPBGlycine decarboxylase, subunit 2; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. C-terminal subunit subfamily. (474 aa)
ADW21411.1L-threonine 3-dehydrogenase. (343 aa)
cddCytidine deaminase; This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis; Belongs to the cytidine and deoxycytidylate deaminase family. (116 aa)
lon2ATP-dependent protease La; ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short- lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner. (818 aa)
hslVATP-dependent protease HslVU, peptidase subunit; Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery. (180 aa)
dtdD-tyrosyl-tRNA(Tyr) deacylase; An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs. Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS. Acts via tRNA- based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D- aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl- tRNA entities in vivo and helps enforce protein L-homochirality. Belongs to the DTD family. (152 aa)
ADW21668.1Phenol hydroxylase component B. (167 aa)
ADW21690.1Cyclase family protein. (269 aa)
ADW21822.1Gamma-glutamyltranspeptidase. (530 aa)
ADW21833.1Antibiotic biosynthesis monooxygenase. (104 aa)
aepAExoenzymes regulatory protein AepA. (481 aa)
amiDN-acetylmuramoyl-L-alanine amidase. (381 aa)
ADW22127.1Indigoidine synthase A like protein. (92 aa)
ADW22128.1Indigoidine synthase A like protein. (189 aa)
pdxTGlutamine amidotransferase, subunit PdxT; Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS. (188 aa)
ADW22286.1Conserved hypothetical protein. (346 aa)
surE35'/3'-nucleotidase SurE; Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates; Belongs to the SurE nucleotidase family. (244 aa)
ADW22393.1Zinc-dependent dehydrogenase. (370 aa)
lon3ATP-dependent protease La; ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short- lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner. (795 aa)
ftsH1Cell division protein FtsH; Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins; Belongs to the AAA ATPase family. In the central section; belongs to the AAA ATPase family. (617 aa)
mtnNMTA/SAH nucleosidase; Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S-adenosylhomocysteine (SAH/AdoHcy) to adenine and the corresponding thioribose, 5'- methylthioribose and S-ribosylhomocysteine, respectively. Belongs to the PNP/UDP phosphorylase family. MtnN subfamily. (221 aa)
ADW22553.1methylcrotonoyl-CoA carboxylase beta chain; 3-methylcrotonyl-CoA carboxylase non-biotin-containing subunit; 3-methylcrotonyl-CoA:carbon dioxide ligase subunit beta; MCCase subunitbeta; 3-methylcrotonyl-CoA carboxylase 2. (560 aa)
ftsH2Cell division protein FtsH; Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins; Belongs to the AAA ATPase family. In the central section; belongs to the AAA ATPase family. (627 aa)
ADW22663.1N-acetylmuramoyl-L-alanine amidase. (368 aa)
ADW22759.1Conserved protein/domain typically associated with flavoprotein oxygenase, Dim6/ntab family. (159 aa)
coaBCPhosphopantothenoylcysteine decarboxylase/phosphopantothenate--cysteine ligase; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. (396 aa)
gdhA1Glutamate dehydrogenase; GDH; Belongs to the Glu/Leu/Phe/Val dehydrogenases family. (424 aa)
ald1Alanine dehydrogenase; Belongs to the AlaDH/PNT family. (369 aa)
ADW22868.1Delta-1-pyrroline-5-carboxylate dehydrogenase; Belongs to the aldehyde dehydrogenase family. (516 aa)
ADW22869.1Proline dehydrogenase/delta-1-pyrroline-5-carboxylate dehydrogenase. (307 aa)
ADW22879.1Zinc-binding dehydrogenase. (344 aa)
ald2Alanine dehydrogenase; Stage V sporulation protein N. (352 aa)
speAArginine decarboxylase; Catalyzes the biosynthesis of agmatine from arginine. (630 aa)
Your Current Organism:
Thermus scotoductus
NCBI taxonomy Id: 743525
Other names: T. scotoductus SA-01, Thermus scotoductus SA-01, Thermus scotoductus str. SA-01, Thermus scotoductus strain SA-01, Thermus sp. SA-01
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