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surE1 surE1 nadE nadE pntA pntA pntAB pntAB pntB pntB nadD nadD ADW21050.1 ADW21050.1 surE2 surE2 deoD deoD ADW21405.1 ADW21405.1 nadB nadB nadA nadA nadC nadC ADW21885.1 ADW21885.1 pncB pncB surE3 surE3 cobB-2 cobB-2
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
surE15'/3'-nucleotidase SurE; Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates; Belongs to the SurE nucleotidase family. (249 aa)
nadENAD+ synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source. (281 aa)
pntANAD(P) transhydrogenase, subunit alpha part 1; Nicotinamide nucleotide transhydrogenase subunit alpha; pyridinenucleotide transhydrogenase, subunit alpha. (375 aa)
pntABNAD(P) transhydrogenase, subunit alpha part 2. (100 aa)
pntBNAD(P) transhydrogenase, subunit beta; The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane; Belongs to the PNT beta subunit family. (450 aa)
nadDNicotinate (nicotinamide) nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). (186 aa)
ADW21050.1Competence/damage-inducible protein; Belongs to the CinA family. (394 aa)
surE25'-nucleotidase; Ecto-nucleotidase; Belongs to the 5'-nucleotidase family. (552 aa)
deoDPurine nucleoside phosphorylase DeoD-type; PNP. (235 aa)
ADW21405.1Purine nucleoside phosphorylase I, inosine and guanosine-specific; The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate. (275 aa)
nadBL-aspartate oxidase. (510 aa)
nadAQuinolinate synthetase complex, subunit A; Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate. (307 aa)
nadCNicotinate-nucleotide diphosphorylase; Carboxylating; Belongs to the NadC/ModD family. (286 aa)
ADW21885.1Putative succinate-semialdehyde dehydrogenase. (477 aa)
pncBPutative nicotinate phosphoribosyltransferase; Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate. Belongs to the NAPRTase family. (507 aa)
surE35'/3'-nucleotidase SurE; Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates; Belongs to the SurE nucleotidase family. (244 aa)
cobB-2NAD-dependent deacetylase; Regulatory protein SIR2homolog; Belongs to the sirtuin family. Class III subfamily. (252 aa)
Your Current Organism:
Thermus scotoductus
NCBI taxonomy Id: 743525
Other names: T. scotoductus SA-01, Thermus scotoductus SA-01, Thermus scotoductus str. SA-01, Thermus scotoductus strain SA-01, Thermus sp. SA-01
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